Professor Dek N Woolfson

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• Active

  Generalised Photocatalysis by Enzymes

  Woolfson, D. N.

  1/12/22 → 30/11/27

  Project: Research

• Mechanism and design of a pH sensor at the organelle-cytoskeleton interface

  Woolfson, D. N.

  1/02/22 → 31/01/25

  Project: Research

• Coiled-coil Technology for Regulating Intracellular Protein-protein Interactions

  Woolfson, D. N.

  1/10/21 → 31/03/25

  Project: Research

• 19-BBSRC-NSF/BIO. Leveraging synthetic biology to probe the rules of cell morphogenesis.

  Woolfson, D. N.

  22/02/21 → 21/02/26

  Project: Research

• Molecular Photonic Breadboards

  Woolfson, D. N.

  1/09/20 → 31/08/25

  Project: Research

• Finished

  BBI Internationalisatoin Programme 2022/23

  Woolfson, D. N.

  1/11/22 → 31/10/23

  Project: Research

• BrisEngBio

  Woolfson, D. N.

  31/01/22 → 30/01/24

  Project: Research

• BrisEngBio

  Woolfson, D. N.

  31/01/22 → 30/01/24

  Project: Research

• BrisEngBio

  Woolfson, D. N.

  31/01/22 → 30/01/24

  Project: Research

• 8083 BrisEngBio - Exemplar Project 1

  Woolfson, D. N.

  31/01/22 → 30/01/24

  Project: Research

• BrisEngBio

  Woolfson, D. N.

  31/01/22 → 30/01/24

  Project: Research

• BrisEngBio

  Woolfson, D. N.

  31/01/22 → 30/01/24

  Project: Research, Parent

• CuPiD: A European Network in Computational Protein Design

  Woolfson, D. N.

  1/07/21 → 30/06/24

  Project: Research

• NovoFold: De novo protein discovery as a tool for understanding the folding conundrum

  Woolfson, D. N.

  3/01/19 → 2/01/21

  Project: Research, Parent

• Design and in vivo assembly of switchable protein-protein interactions for transcription regulation

  Woolfson, D. N.

  1/12/18 → 30/11/22

  Project: Research

  • Coiled Coil 100%
  • Protein Tertiary Structure 50%
  • Static Electricity 25%
  • X-Ray Crystallography 25%
  • Homotetramer 25%

• BBSRC FTMA2 BB/S507891/1 Innovation Placement - Prof Dek Woolfson

  Woolfson, D. N.

  1/11/18 → 31/03/20

  Project: Research

• BADASS: Barrel Array Diagnostics And SenSing

  Woolfson, D. N.

  1/06/18 → 30/11/19

  Project: Research

  • Coiled Coil 100%
  • Protein Data Bank 50%
  • Small Molecule 50%
  • Solution and Solubility 33%
  • Protein Structure 25%

• Rational computational protein design in ISAMBARD: new approaches, folds and functions

  Woolfson, D. N.

  1/05/18 → 30/04/23

  Project: Research

  • Dynamics 100%
  • Virtual Reality 100%
  • Coiled Coil 66%
  • Molecular Dynamics 66%
  • Open Source 44%

• University of Bristol SEDGLEY UKRI Innovation Fellowships: BBSRC Flexible Talent Mobility Accounts

  Woolfson, D. N.

  1/11/17 → 31/03/19

  Project: Research, Parent

• BrisSynBio Flexible Talent Mobility Award

  Woolfson, D. N.

  1/11/17 → 31/03/19

  Project: Research

• 8083 *CLOSED* BBSRC FTMA Woolfson

  Woolfson, D. N.

  1/08/16 → 31/03/19

  Project: Research

• 8083 BBSRC BRIS SYN BIO

  Woolfson, D. N.

  1/08/16 → 30/07/19

  Project: Research

  • Coiled Coil 100%
  • Bacterial Microcompartment 57%
  • Structural Detail 42%
  • Nanoparticles 42%
  • Excitation Energy 42%

• 8043 EPSRC VIA LEEDS EP/N013573/1 (closed)

  Woolfson, D. N.

  1/02/16 → 31/01/22

  Project: Research

  • Protein-Protein Interaction 100%
  • Alanine 91%
  • Coiled Coil 80%
  • Mutagenesis 40%
  • Energy Transfer 20%

• Developing libraries for orthosteric inhibition of protein-protein interactions by mimicry of hot-spot constellations.

  Woolfson, D. N.

  1/02/16 → 31/01/22

  Project: Research

• BrisSynBio / SAGE Vaccines

  Woolfson, D. N.

  13/10/14 → 30/09/21

  Project: Research

  • Enzyme 100%
  • Self-Assembling Peptide 66%
  • C-Terminus 66%
  • Dynamics 66%
  • Chimeric Protein 66%

• Development of supramolecular assemblies for enhancing cellular productivity and the synthesis of fine chemicals and biotheraputics.

  Woolfson, D. N., Cryan, M. J. & Verkade, P.

  1/10/14 → 30/09/19

  Project: Research, Parent

  • Enzyme 100%
  • Coiled Coil 66%
  • Structural Detail 50%
  • Nanoparticles 50%
  • Nanomaterial 50%

• BrisSynBio: Bristol Centre for Synthetic Biology

  Woolfson, D. N.

  31/07/14 → 30/07/19

  Project: Research

  • Farnesol 100%

• BrisSynBio supplementary funding 2021/22

  Woolfson, D. N.

  31/07/14 → 31/01/20

  Project: Research, Parent

  • 310 Helix 100%
  • Subcellular Localization 100%
  • De Novo Design 100%
  • Protein Assembly 50%
  • Basic Peptide 50%

• BrisSynBio: Bristol Centre for Synthetic Biology

  Woolfson, D. N.

  31/07/14 → 31/03/22

  Project: Research

  • Protocell 100%
  • Anabolism 91%
  • Enzyme 74%
  • Coiled Coil 63%
  • Protein-Protein Interaction 48%

• BrisSynBio: Bristol Centre for Synthetic Biology

  Woolfson, D. N.

  31/07/14 → 30/07/19

  Project: Research

  • Mammalian Cell 100%
  • Serial Analysis of Gene Expression 100%
  • Internalization 100%
  • Nanoparticle 100%
  • Cages 100%

• BrisSynBio: Bristol Centre for Synthetic Biology

  Woolfson, D. N.

  1/07/14 → 30/06/19

  Project: Research

  • Enzyme 100%
  • C-Terminus 66%
  • Dynamics 66%
  • Chimeric Protein 66%
  • Nanocage 66%

• SAGEs: Self-assembled peptide-based cages for the presentation, encapsulation and delivery of bioactive molecules to cells in culture

  Woolfson, D. N.

  1/01/14 → 31/12/17

  Project: Research, Parent

  • Enzyme 100%
  • C-Terminus 100%
  • Chimeric Protein 100%
  • Virion 100%
  • Solution and Solubility 66%

• SynbiCITE - Innovation and knowledge Centre in Synthetic Biology

  Woolfson, D. N.

  1/10/13 → 30/09/18

  Project: Research

• Protein-Protein Interaction Inhibitors.

  Woolfson, D. N.

  1/05/13 → 1/09/13

  Project: Research

  • Coiled Coil 100%
  • Protein-Protein Interaction 100%

• Hexaporins: the rational design of transmembrane channels.

  Woolfson, D. N.

  15/08/12 → 14/08/15

  Project: Research

  • Protein Design 100%
  • Coiled Coil 75%
  • Protein Structure 75%
  • Conformation 45%
  • Amino Acids 45%

• Hexaporins: the rational design of transmembrane channels.

  Woolfson, D. N.

  15/08/12 → 14/08/15

  Project: Research, Parent

  • Mammalian Cell 100%
  • Serial Analysis of Gene Expression 100%
  • Internalization 100%
  • Nanoparticle 100%
  • Cages 100%

• Electron Delocalization in Peptides and Proteins

  Woolfson, D. N.

  1/10/11 → 1/10/14

  Project: Research

  • Coiled Coil 100%
  • Static Electricity 63%
  • Protein Structure 44%
  • Peptide Sequence 30%
  • Solution and Solubility 30%

• alpha-Helical peptide hydrogels as instructive scaffolds for 3D cell culture and tissue engineering

  Woolfson, D. N.

  1/11/10 → 1/05/14

  Project: Research

  • Microtubule Associated Protein 2 100%
  • Cell Culture 100%
  • Arginylglycylaspartylserine 100%
  • Tissue Repair 100%
  • Glial Fibrillary Acidic Protein 100%

• A BIOMOLECULAR-DESIGN APPROACH IN SYNTHETIC BIOLOGY: TOWARDS SYNTHETIC CYTOSKELETONS

  Woolfson, D. N.

  1/07/09 → 1/07/13

  Project: Research

  • Coiled Coil 100%
  • Self Assembly 50%
  • Biological Product 50%
  • Protocell 25%

• SYNTHETIC COMPONENTS NETWORK: TOWARDS SYNTHETIC BIOLOGY FROM THE BOTTOM UP

  Woolfson, D. N.

  1/01/09 → 1/07/12

  Project: Research

  • Leucine 100%
  • Protein Structure 100%
  • Helix Bundle 50%
  • Crystal Structure 50%
  • X Ray 50%

• CONSUMABLES

  Woolfson, D. N.

  1/01/08 → 1/04/11

  Project: Research

• DECORATING SELF-ASSEMBLED NANO-TO-MESOSCALE PEPTIDE FIBRES WITH FUNCTIONAL PROTEINS AND PROTEIN COMPLEXES

  Woolfson, D. N.

  1/10/07 → 1/10/11

  Project: Research

  • Biomaterial 100%
  • Electron Microscopy 66%
  • Self Assembly 50%
  • Nanometre 33%
  • Fiber System 33%

• EXPLORING THE DESIGN, CHARACTERISATION AND POTENTIAL APPLICATIONS OF A-HELIX-BASED PEPTIDE HYDROGELS

  Woolfson, D. N.

  2/07/07 → 2/07/08

  Project: Research

• TOWARDS BETTER PREDICTIONS, DESIGNS AND ENGINEERING OF COILED-COIL PROTEIN-PROTEIN INTERACTIONS

  Woolfson, D. N.

  2/01/06 → 2/01/09

  Project: Research

• TOWARDS BETTER PREDICTIONS, DESIGNS AND ENGINEERING OF COILED-COIL PROTEIN-PROTEIN INTERACTIONS w RA0402

  Woolfson, D. N.

  2/01/06 → 2/01/07

  Project: Research

• SYSTEMATIC ANALYSIS OF HOW SEQUENCE AFFECTS ALPHA TO BETA STRUCTURAL SWITCHING

  Woolfson, D. N.

  17/10/05 → 17/05/06

  Project: Research

• SYSTEMATIC ANALYSIS OF HOW SEQUENCE AFFECTS ALPHA TO BETA STRUCTURAL SWITCHING w. RA0408

  Woolfson, D. N.

  17/10/05 → 17/10/06

  Project: Research

• COMBINING STEM CELLS, SELF-ASSEMBLING-PEPTIDE SCAFFOLDS AND NOVEL BIOREACTORS IN CARTILAGE ENGINEERING

  Woolfson, D. N.

  1/08/05 → 1/05/07

  Project: Research

• EXPLORING THE NANOSCALE STRUCTURE AND ASSEMBLY OF A DESIGNED PROTEIN FIBRE

  Woolfson, D. N.

  1/08/05 → 1/06/07

  Project: Research

• EXPLORING THE NANOSCALE STRUCTURE AND ASSEMBLY OF A DESIGNED PROTEIN FIBRE with RA0417

  Woolfson, D. N.

  1/08/05 → 1/08/06

  Project: Research