Personal profile

Research interests

I am a health economist working in musculoskeletal research affecting millions of patients worldwide.  I collaborate with national and international academic institutions and industry to design and deliver large programmes of research. Recent clinical areas worked on include orthopaedic surgery in trauma and elective hip, knee, and ankles surgery; rheumatology; medical devices; breast cancer; obstetrics; stroke; children with cronic conditions; and evaluation of NHS services delivery.

 

I am chief investigator of HIPPY (Hip Programme Prosthesis Study for the Younger THR patients), an NIHR-funded Programme Grant for Applied Research of circa £3m in collaboration with Ashley Blom (co-CI, Sheffield), Mike Whitehouse (UoB, THS), Mike Reed (Northumbria, NJR), David Sochart (SWLEOC) and research teams at the Musculoskeletal Research Unit, North Bristol Trust, and the Bristol Trials Centre. HIPPY is a programme of studies in evidence synthesis, large linked RWE data analyses, and economic modelling to find out which implants are best for patients under 70 years of age. It includes the largest surgical trial in orthopaedic implants where we will randomise nearly 8,000 elective hip replacement patients under 70 years in circa 100 hospitals across England and Wales.

 

My interests lie in using evidence synthesis methods and "big data"to inform cost-effectiveness models. I led two completed NIHR grants using these methods, lead or co-lead the economic evaluation components in research infrastructure grants such as the contact for analyses of NJR data and the Bristol NICE Technology Asssesment Group, and over 20 other studies based at Bristol, Oxford, Bournemouth, Salisbury, and other organisations across the UK. 

 

I serve in the NIHR Programme Grants for Applied Research research funding committe sub-panel A after serving two terms in the NIHR Research for Patient Benefit  - Southwest regional advisory panel. I provide advice to NICE and INFARMED (NICE equivalent in Portugal) appraising submissions of medicines for approval in the English and Portuguese NHS.

 

I supervise three PhD students, lead the Evidence-Based Practice in Medicine helical theme lead for the undergraduate medical programme MB21, co-lead of the Quantitative methods for economic evaluation and policy analysis module of MSc Health Economics and Policy Analysis, and contribute to teaching in several other MSc and CPD short courses delivered at Bristol and abroad. 

 

I have a PhD in Economics, having studied economic theory and finance in post-graduate programmes in the USA and Portugal. My dissertation looked at economic growth models and tested the endogenous influence of population growth on economic growth in 202 countries.

External positions

Health economics expert, INFARMED

2021 → …

Regional Advisory Panel member, NIHR - RFPB

2017 → …

Structured keywords and research groupings

  • PolicyBristolMethodologiesAndDataAnalysis
  • Health Economics
  • Economic evaluation alongside trials
  • Trial methodology
  • Evidence synthesis
  • Cost-effectiveness modelling
  • National Joint Registry

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