20062020

Research output per year

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Research Output

2020

Hypertension, Antihypertensive Use and the Delayed-Onset of Huntington's Disease

Steventon, J. J., Rosser, A. E., Hart, E. & Murphy, K., 4 Feb 2020, In : Movement Disorders. 7, 3, 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
17 Downloads (Pure)
Open Access
File
8 Downloads (Pure)

Retrograde Blood Flow in the Internal Jugular Veins of Humans With Hypertension May Have Implications for Cerebral Arterial Blood Flow

Rodrigues, J. C. L., Strelko, G., Warnert, E. A., Burchell, A. E., Neumann, S., Radcliffe, L., Harris, A. D., Chant, B. J., Bowles, R., Nightingale, A. K., Wise, R. G., Paton, J. F. R. & Hart, E. C. J., 10 Mar 2020, In : European Radiology.

Research output: Contribution to journalArticle (Academic Journal)

2019

Cerebral Blood Flow Response to Simulated Hypovolemia in Essential Hypertension: A Magnetic Resonance Imaging Study

Neumann, S., Burchell, A. E., Rodrigues, J. C. L., Lawton, C. B., Burden, D., Underhill, M., Kobetić, M. D., Adams, Z. H., Brooks, J. C. W., Nightingale, A. K., Paton, J. F. R., Hamilton, M. C. K. & Hart, E. C., 1 Dec 2019, In : Hypertension. 74, 6, p. 1391-1398 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
79 Downloads (Pure)

Repaired coarctation of the aorta, persistent arterial hypertension and the selfish brain

Rodrigues, J. C. L., Jaring, M. F. R., Werndle, M. C., Mitrousi, K., Lyen, S. M., Nightingale, A. K., Hamilton, M. C. K., Curtis, S. L., Manghat, N. E., Paton, J. F. R. & Hart, E. C., 7 Nov 2019, In : Journal of Cardiovascular Magnetic Resonance. 21, 10 p., 68 (2019) .

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
78 Downloads (Pure)
2018

Antihypertensive Treatment Fails to Control Blood Pressure During Exercise

Chant, B., Bakali, M., Hinton, T., Burchell, A. E., Nightingale, A. K., Paton, J. F. R. & Hart, E. C., 1 Jul 2018, In : Hypertension. 72, 1, p. 102-109 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
10 Citations (Scopus)
244 Downloads (Pure)

Left ventricular extracellular volume fraction and atrioventricular interaction in hypertension

Rodrigues, J. C. L., Erdei, T., Dastidar, A. G., Szantho, G., Burchell, A. E., Ratcliffe, L. E. K., Hart, E. C., Nightingale, A. K., Paton, J. F. R., Manghat, N. E. & Hamilton, M. C. K., 19 Sep 2018, In : European Radiology. 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
142 Downloads (Pure)

Noctural dipping status and left ventricular hypertrophy: A cardiac magnetic resonance imaging study

Rodrigues, J. C. L., Amadu, A. M., Ghosh Dastidar, A., Harries, I., Burchell, A. E., Ratcliffe, L. E. K., Hart, E. C., Hamilton, M. C. K., Paton, J. F. R., Nightingale, A. K. & Manghat, N. E., Apr 2018, In : Journal of Clinical Hypertension. 20, 4, p. 784-793 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
183 Downloads (Pure)
Open Access
File
228 Downloads (Pure)
2017

Autonomic control of body temperature and blood pressure: influences of female sex hormones

Charkoudian, N., Hart, E. C. J., Barnes, J. N. & Joyner, M. J., 1 Jun 2017, In : Clinical Autonomic Research. 27, 3, p. 149-155 7 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
26 Citations (Scopus)
397 Downloads (Pure)

Cardiac magnetic resonance imaging provides a new insight in hypertensive heart disease – a reply

Rodrigues, J., Rohan, S., Ghosh Dastidar, A., Trickey, A., Szantho, G., Ratcliffe, L., Burchell, A., Hart, E., Bucciarelli-Ducci, C., Hamilton, M. C. K., Nightingale, A., Paton, J., Manghat, N. E. & Maclver, D., 7 Mar 2017, In : Journal of Clinical Hypertension. 19, 3, p. 335–336 2 p.

Research output: Contribution to journalLetter (Academic Journal)

Open Access
File
131 Downloads (Pure)

Carotid body resection for sympathetic modulation in systolic heart failure – results from first-in-man study

Niewinski, P., Janczak, D., Rucinski, A., Tubek, S., Engelman, Z. J., Piesiak, P., Jazwiec, P., Banasiak, W., Fudim, M., Sobotka, P. A., Javaheri, S., Hart, E. C. J., Paton, J. F. R. & Ponikowski, P., Mar 2017, In : European Journal of Heart Failure. 19, 3, p. 391–400 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
41 Citations (Scopus)
275 Downloads (Pure)

Comprehensive First-Line Magnetic Resonance Imaging in Hypertension: Experience From a Single-Center Tertiary Referral Clinic

Burchell, A. E., Rodrigues, J. C. L., Charalambos, M., Ratcliffe, L. E. K., Hart, E. C., Paton, J. F. R., Baumbach, A., Manghat, N. E. & Nightingale, A. K., Jan 2017, In : Journal of Clinical Hypertension. 19, 1, p. 13–22 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
218 Downloads (Pure)

ECG strain pattern in hypertension is associated with myocardial cellular expansion and diffuse interstitial fibrosis: a multi-parametric cardiac magnetic resonance study

Rodrigues, J. C. L., Amadu, A. M., Ghosh Dastidar, A., McIntyre, B., Szantho, G. V., Lyen, S., Godsave, C., Ratcliffe, L. E. K., Burchell, A. E., Hart, E. C., Hamilton, M. C. K., Nightingale, A. K., Paton, J. F. R., Manghat, N. E. & Bucciarelli-Ducci, C., Apr 2017, In : European Heart Journal - Cardiovascular Imaging. 18, 4, p. 441-450 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
12 Citations (Scopus)
199 Downloads (Pure)

Electrocardiographic detection of hypertensive left atrial enlargement in the presence of obesity: re-calibration against cardiac magnetic resonance

Rodrigues, J. C. L., Erdei, T., Ghosh Dastidar, A., McIntyre, B., Burchell, A. E., Ratcliffe, L. E. K., Hart, E. C. J., Hamilton, M. C. K., Paton, J. F. R., Nightingale, A. K. & Manghat, N. E., Mar 2017, In : Journal of Human Hypertension. 31, 3, p. 212–219 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
299 Downloads (Pure)

Evaluating the carotid bodies and renal nerves as therapeutic targets for hypertension

McBryde, F., Hart, E., Ramchandra, R. & Paton, J., 1 May 2017, In : Autonomic Neuroscience: Basic and Clinical. 204, p. 126-130 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
260 Downloads (Pure)

Hypertensive heart disease versus hypertrophic cardiomyopathy: multi-parametric cardiovascular magnetic resonance discriminators when end-diastolic wall thickness ≥ 15 mm

Rodrigues, J. C. L., Rohan, S., Ghosh Dastidar, A., Harries, I., Lawton, C. B., Ratcliffe, L. E., Burchell, A. E., Hart, E. C., Hamilton, M. C. K., Paton, J. F. R., Nightingale, A. K. & Manghat, N. E., Mar 2017, In : European Radiology. 27, 3, p. 1125-1135 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
13 Citations (Scopus)
339 Downloads (Pure)

Recording sympathetic nerve activity in conscious humans and other mammals: guidelines and the road to standardization

Hart, E. C., Head, G. A., Carter, J. R., Wallin, B. G., May, C. N., Hamza, S. M., Hall, J. E., Charkoudian, N. & Osborn, J. W., 15 May 2017, In : AJP - Heart and Circulatory Physiology. 312, 5, p. H1031-H1051 21 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
42 Citations (Scopus)
184 Downloads (Pure)
2016

Comprehensive characterisation of hypertensive heart disease left ventricular phenotypes

Paton, J., Rodrigues, J., Hart, E. & Bucciarelli-Ducci, C., Oct 2016, In : Heart. 102, 20, p. 1671-1679 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
35 Citations (Scopus)
204 Downloads (Pure)

Controversies Surrounding Renal Denervation: Lessons Learned From Real-World Experience in Two United Kingdom Centers

Burchell, A. E., Chan, K., Ratcliffe, L. E. K., Hart, E. C., Saxena, M., Collier, D. J., Jain, A. K., Mathur, A., Knight, C. J., Caulfield, M. J., Paton, J. F. R., Nightingale, A. K., Lobo, M. D. & Baumbach, A., 4 Jun 2016, In : Journal of Clinical Hypertension. 18, 6, p. 585-592 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
254 Downloads (Pure)

Is High Blood Pressure Self-Protection for the Brain?

Warnert, E. A., Rodrigues, J. C., Burchell, A. E., Neumann, S., Ratcliffe, L. E., Manghat, N. E., Harris, A. D., Adams, Z. H., Nightingale, A. K., Wise, R. G., Paton, J. F. & Hart, E. C., Dec 2016, In : Circulation Research. 119, 12, p. e140-e151 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
35 Citations (Scopus)
244 Downloads (Pure)

Prevalence and predictors of asymmetric hypertensive heart disease: insights from cardiac and aortic function with cardiovascular magnetic resonance

Rodrigues, J. C. L., Amadu, A. M., Dastidar, A. G., Hassan, N., Lyen, S. M., Lawton, C. B., Ratcliffe, L. E., Burchell, A. E., Hart, E. C., Hamilton, M. C. K., Paton, J. F. R., Nightingale, A. K. & Manghat, N. E., Dec 2016, In : European Heart Journal - Cardiovascular Imaging. 17, 12, 9 p., jev329.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
9 Citations (Scopus)
203 Downloads (Pure)

Purinergic receptors in the carotid body as a new drug target for controlling hypertension

Pijacka, W., Moraes, D. J. D. A., Ratcliffe, L. E. K., Nightingale, A. K., Hart, E. C. J., da Silva, M., Machado, B., McBryde, F. D., Abdala Sheikh, A. P., Ford, A. & Paton, J. F. R., Oct 2016, In : Nature Medicine. 22, 10, p. 1151-1159 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
63 Citations (Scopus)
218 Downloads (Pure)

Quantifying sympathetic neuro-haemodynamic transduction at rest in humans: Insights into sex, ageing and blood pressure control

Briant, L. J. B., Burchell, A. E., Ratcliffe, L. E. K., Charkoudian, N., Nightingale, A. K., Paton, J. F. R., Joyner, M. J. & Hart, E. C., 1 Sep 2016, In : Journal of Physiology. 594, 17, p. 4753-4768 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
27 Citations (Scopus)
249 Downloads (Pure)

The effect of obesity on electrocardiographic detection of hypertensive left ventricular hypertrophy: Recalibration against cardiac magnetic resonance

Rodrigues, J. C. L., McIntyre, B., Dastidar, A. G., Lyen, S. M., Ratcliffe, L. E., Burchell, A. E., Hart, E. C., Bucciarelli-Ducci, C., Hamilton, M. C. K., Paton, J. F. R., Nightingale, A. K. & Manghat, N. E., 1 Mar 2016, In : Journal of Human Hypertension. 30, 3, p. 197-203 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
7 Citations (Scopus)
270 Downloads (Pure)

The relationship between left ventricular wall thickness, myocardial shortening and ejection fraction in hypertensive heart disease: insights from cardiac magnetic resonance: LVH independently augments EF in hypertension

Rodrigues, J. C. L., Rohan, S., Dastidar, A. G., Trickey, A., Szantho, G., Ratcliffe, L. E. K., Burchell, A. E., Hart, E. C., Bucciarelli-Ducci, C., Hamilton, M. C. K., Nightingale, A. K., Paton, J. F. R., Manghat, N. E. & MacIver, D. H., Nov 2016, In : Journal of Clinical Hypertension. 18, 11, p. 1119-1127 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
11 Citations (Scopus)
182 Downloads (Pure)

Unilateral Carotid Body Resection in Resistant Hypertension: A Safety and Feasibility Trial

Narkiewicz, K., Ratcliffe, L., Hart, E., Briant, L., Chrostowska, M., Wolf, J., Szyndler, A., Hering, D., Abdala Sheikh, A. A., Manghat, N. E., Burchell, A., Durant, C., Lobos, M. D., Sobotka, P. A., Patel, N., Leiter, J. C., Engelman, Z. J., Nightingale, A. & Paton, J., Aug 2016, In : Journal of the American College of Cardiology. 1, 5, p. 313-324 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
50 Citations (Scopus)
211 Downloads (Pure)
2015

Are systolic function and ejection fraction interchangeable? New insights from cardiovascular magnetic resonance and in-vivo validation of mathematical models of LV function

Rodrigues, J. C., Rohan, S., Dastidar, A. G., Burchell, A. E., Ratcliffe, L. E., Hart, E. C., Nightingale, A. K., Paton, J. F., Bucciarelli-Ducci, C., Hamilton, M., Manghat, N. E. & MacIver, D. H., 3 Feb 2015, In : Journal of Cardiovascular Magnetic Resonance. 17, 1, p. 1-2 2 p., P325.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
202 Downloads (Pure)

Improving the poor diagnostic accuracy of the ECG at detecting prognostically significant left ventricular hypertrophy in hypertensive patients

Rodrigues, J. C., McIntyre, B., Dastidar, A. G., Burchell, A. E., Ratcliffe, L. E., Hart, E. C., Paton, J. F., Bucciarelli-Ducci, C., Hamilton, M., Nightingale, A. K. & Manghat, N. E., 3 Feb 2015, In : Journal of Cardiovascular Magnetic Resonance. 17(Suppl 1), 2 p., P234.

Research output: Contribution to journalSpecial issue (Academic Journal)

Open Access
File
197 Downloads (Pure)

Insights from cardiovascular magnetic resonance imaging supporting the selfish brain hypothesis of arterial hypertension

Rodrigues, J. C., Hart, E. C., Hassan, N., Williams, M., Burchell, A. E., Ratcliffe, L. E., Nightingale, A. K., Paton, J. F. & Manghat, N. E., 3 Feb 2015, In : Journal of Cardiovascular Magnetic Resonance. 17, p. 1-2 2 p., P405.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
200 Downloads (Pure)

Neural control of the circulation: how sex and age differences interact in humans

Joyner, M. J., Barnes, J. N., Hart, E. C., Wallin, B. G. & Charkoudian, N., 1 Jan 2015, In : Comprehensive Physiology. 5, 1, p. 193-215 23 p.

Research output: Contribution to journalArticle (Academic Journal)

41 Citations (Scopus)

Oral Contraceptive Use, Muscle Sympathetic Nerve Activity, and Systemic Hemodynamics in Young Women

Harvey, R. E., Hart, E. C., Charkoudian, N., Curry, T. B., Carter, J. R., Fu, Q., Minson, C. T., Joyner, M. J. & Barnes, J. N., Sep 2015, In : Hypertension. 66, 3, p. 590-7 8 p.

Research output: Contribution to journalArticle (Academic Journal)

28 Citations (Scopus)

Phenotyping patterns of left ventricular remodeling and hypertrophy in systemic hypertension by cardiac magnetic resonance (CMR)

Rodrigues, J. C., Lyen, S., Dastidar, A. G., Hassan, N., Burchell, A. E., Ratcliffe, L. E., Hart, E. C., Bucciarelli-Ducci, C., Hamilton, M., Paton, J. F., Nightingale, A. K. & Manghat, N. E., 3 Feb 2015, In : Journal of Cardiovascular Magnetic Resonance. 17, P323, p. 1-2 2 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
189 Downloads (Pure)

Should we screen for intracranial aneurysms (IAs) in systemic hypertension at the time of cardiac magnetic resonance (CMR)?

Rodrigues, J. C., Hassan, N., Williams, M., Burchell, A. E., Ratcliffe, L. E., Hamilton, M., Hart, E. C., Nightingale, A. K., Paton, J. F. & Manghat, N. E., 3 Feb 2015, In : Journal of Cardiovascular Magnetic Resonance. 17, 1, p. 1-2 2 p., P411.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
197 Downloads (Pure)

Sympathetic regulation of blood pressure in normotension and hypertension: When sex matters

Briant, L. J. B., Charkoudian, N. & Hart, E. C., 18 Dec 2015, In : Experimental Physiology.

Research output: Contribution to journalArticle (Academic Journal)

31 Citations (Scopus)

The major cerebral arteries proximal to the Circle of Willis contribute to cerebrovascular resistance in humans

Warnert, E. A., Hart, E. C., Hall, J. E., Murphy, K. & Wise, R. G., 20 Nov 2015, In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticle (Academic Journal)

17 Citations (Scopus)
2014

Aging enhances autonomic support of blood pressure in women

Barnes, J. N., Hart, E. C., Curry, T. B., Nicholson, W. T., Eisenach, J. H., Wallin, B. G., Charkoudian, N. & Joyner, M. J., Feb 2014, In : Hypertension. 63, 2, p. 303-8 6 p.

Research output: Contribution to journalArticle (Academic Journal)

53 Citations (Scopus)

CrossTalk opposing view: Which technique for controlling resistant hypertension? Carotid chemoreceptor denervation/modulation

Ratcliffe, L. E. K., Pijacka, W., McBryde, F. D., Abdala, A. P., Moraes, D. J., Sobotka, P. A., Hart, E. C., Narkiewicz, K., Nightingale, A. K. & Paton, J. F. R., 15 Sep 2014, In : Journal of Physiology. 592, Pt 18, p. 3941-4 4 p.

Research output: Contribution to journalArticle (Academic Journal)

8 Citations (Scopus)

Deep brain stimulation for the treatment of resistant hypertension

O'Callaghan, E. L., McBryde, F. D., Burchell, A. E., Ratcliffe, L. E. K., Nicolae, L., Gillbe, I., Carr, D., Hart, E. C., Nightingale, A. K., Patel, N. K. & Paton, J. F. R., Nov 2014, In : Current Hypertension Reports. 16, 11, p. 493

Research output: Contribution to journalArticle (Academic Journal)

11 Citations (Scopus)

Dissociation between blood pressure and heart rate response to hypoxia after bilateral carotid body removal in men with systolic heart failure

Niewinski, P., Janczak, D., Rucinski, A., Tubek, S., Engelman, Z. J., Jazwiec, P., Banasiak, W., Sobotka, P. A., Hart, E. C. J., Paton, J. F. R. & Ponikowski, P., Mar 2014, In : Experimental Physiology. 99, 3, p. 552-61 10 p.

Research output: Contribution to journalArticle (Academic Journal)

30 Citations (Scopus)

Forearm vasodilator responses to a β-adrenergic receptor agonist in premenopausal and postmenopausal women

Harvey, R. E., Barnes, J. N., Charkoudian, N., Curry, T. B., Eisenach, J. H., Hart, E. C. & Joyner, M. J., 1 Jun 2014, In : Physiological Reports. 2, 6

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

Rebuttal from L. E. K. Ratcliffe, W. Pijacka, F. D. McBryde, A. P. Abdala, D. J. Moraes, P. A. Sobotka, E. C. Hart, K. Narkiewicz, A. K. Nightingale and J. F. R. Paton

Ratcliffe, L. E. K., Pijacka, W., McBryde, F. D., Abdala, A. P., Moraes, D. J., Sobotka, P. A., Hart, E. C., Narkiewicz, K., Nightingale, A. K. & Paton, J. F. R., 15 Sep 2014, In : Journal of Physiology. 592, Pt 18, p. 3949-50 2 p.

Research output: Contribution to journalArticle (Academic Journal)

Sympathetic nerve activity and peripheral vasodilator capacity in young and older men

Hart, E. C., Wallin, B. G., Barnes, J. N., Joyner, M. J. & Charkoudian, N., Mar 2014, In : AJP - Heart and Circulatory Physiology. 306, 6, p. H904-9

Research output: Contribution to journalArticle (Academic Journal)

17 Citations (Scopus)

Sympathetic neural regulation of blood pressure: influences of sex and aging

Hart, E. C. J. & Charkoudian, N., Jan 2014, In : Physiology (Bethesda, Md.). 29, 1, p. 8-15 8 p.

Research output: Contribution to journalArticle (Academic Journal)

66 Citations (Scopus)
2013

Carotid body removal for treatment of chronic systolic heart failure

Niewiński, P., Janczak, D., Rucinski, A., Jazwiec, P., Sobotka, P. A., Engelman, Z. J., Fudim, M., Tubek, S., Jankowska, E. A., Banasiak, W., Hart, E. C. J., Paton, J. F. R. & Ponikowski, P., 3 Oct 2013, In : International Journal of Cardiology. 168, 3, p. 2506-9 4 p.

Research output: Contribution to journalArticle (Academic Journal)

64 Citations (Scopus)

Chemohypersensitivity and autonomic modulation of venous capacitance in the pathophysiology of acute decompensated heart failure

Burchell, A. E., Sobotka, P. A., Hart, E. C., Nightingale, A. K. & Dunlap, M. E., Jun 2013, In : Current Heart Failure Reports. 10, 2, p. 139-46 8 p.

Research output: Contribution to journalArticle (Academic Journal)

19 Citations (Scopus)

Erratum: The carotid body as a therapeutic target for the treatment of sympathetically mediated diseases (Hypertension (2013) 61 (5-13))

Paton, J. F. R., Sobotka, P. A., Fudim, M., Engelman, Z. J., Hart, E. C. J., McBryde, F. D., Abdala, A. P., Marina, N., Gourine, A. V., Lobo, M., Patel, N., Burchell, A., Ratcliffe, L. & Nightingale, A., Feb 2013, In : Hypertension. 61, 2

Research output: Contribution to journalComment/debate (Academic Journal)

Relationship between sympathetic nerve activity and aortic wave reflection characteristics in postmenopausal women

Hart, E. C., Charkoudian, N., Joyner, M. J., Barnes, J. N., Curry, T. B. & Casey, D. P., Sep 2013, In : Menopause. 20, 9, p. 967-72 6 p.

Research output: Contribution to journalArticle (Academic Journal)

16 Citations (Scopus)

Response to role of the carotid body in obesity-related sympathoactivation

Paton, J. F. R., Sobotka, P. A., Fudim, M., Engelman, Z. J., Hart, E. C. J., McBryde, F. D., Abdala, A. P., Marina, N., Gourine, A. V., Lobo, M., Patel, N., Burchell, A., Ratcliffe, L. & Nightingale, A., Jun 2013, In : Hypertension. 61, 6, p. e58

Research output: Contribution to journalLetter (Academic Journal)

2 Citations (Scopus)