Professor Emma Raven

BSci (Leic.), PhD(N'cle)

  • BS8 1TS

20092020

Research output per year

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Personal profile

Research interests

The work of my research is to understand the catalytic activity and biological function in heme containing enzymes. Heme is the prosthetic group found in a number of biologically important proteins (from haemoglobin to catalases) which have a diverse range of biological functions including electron transfer, transportation of gases and chemical catalysis. Our work is focused in three main areas: peroxidases, dioxygenases and the role of heme in the cell. We use kinetic and spectroscopic methods to understand the mechanism and function of heme enzymes, and we collaborate with structural biologists (Prof Peter Moody, University of Leicester) to provide a structural framework for our experiments.

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Projects

Research Output

Heme peroxidase—Trapping intermediates by cryo neutron crystallography

Kwon, H., Schrader, T. E., Ostermann, A., Blakeley, M. P., Raven, E. L. & Moody, P. C. E., 2020, Methods in Enzymology. Elsevier Academic Press Inc, p. 379-389 11 p. (Methods in Enzymology; vol. 634).

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

  • Rewiring the “Push-Pull” Catalytic Machinery of a Heme Enzyme Using an Expanded Genetic Code

    Ortmayer, M., Fisher, K., Basran, J., Wolde-Michael, E. M., Heyes, D. J., Levy, C., Lovelock, S. L., Anderson, J. L. R., Raven, E. L., Hay, S., Rigby, S. E. J. & Green, A. P., 21 Feb 2020, In : ACS Catalysis. 10, 4, p. 2735-2746 12 p.

    Research output: Contribution to journalArticle (Academic Journal)

  • Visualizing the protons in a metalloenzyme electron proton transfer pathway

    Kwon, H., Basran, J., Devos, J. M., Suardiaz Del Rio, R., Van Der Kamp, M. W., Mulholland, A. J., Schrader, T. E., Ostermann, A., Blakeley, M. P., Moody, P. C. E. & Raven, E., 9 Mar 2020, In : Proceedings of the National Academy of Sciences of the United States of America.

    Research output: Contribution to journalArticle (Academic Journal)

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    Activities

    • 1 Visiting an external academic institution

    SPring 8, Japan Synchrotron Radiat Res Inst

    Emma Raven (Visiting researcher)

    5 Jun 2019

    Activity: Visiting an external institution typesVisiting an external academic institution