Projects per year
Personal profile
Research interests
My research involves statistical genetics of complex traits and disorders using mainly genome-wide association data from the Avon Longitudinal Study of Parents and Children (ALSPAC) and collaborating with other groups to achieve large-scale analyses. In addition, I am involved in investigating gene-environment interactions utilizing the rich dataset of environmental factors collected for ALSPAC participants.
I am especially interested in the genetic basis of sex differences in complex disorders, the role of sex chromosomes in sexually dimorphic traits and disorders and developing methods to incorporate sex chromosomes in genome-wide association studies.
The phenotypes that I am interested in include sexually dimorphic psychiatric disorders, such as ADHD, autism, schizophrenia and depression as well as obesity and BMI.
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Projects
- 1 Finished
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Using genetic data to identify early determinants and causal environmental risk factors for Alzheimer’s disease
Anderson, E. L., Stergiakouli , E., Howe, L. D. & Ben-Shlomo, Y.
12/05/16 → 1/10/19
Project: Research
Research Output
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A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank
Leppert, B., Millard, L. A. C., Riglin, L., Davey Smith, G., Thapar, A., Tilling, K. M., Walton, E. & Stergiakouli, E., 11 May 2020, In : PLoS Genetics. 16, 5, 20 p., e1008185.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile -
ADHD and depression: investigating a causal explanation
Riglin, L., Leppert, B., Dardani, C., Thapar, A., Rice, F., O'Donovan, M. C., Davey Smith, G., Stergiakouli, E., Tilling, K. M. & Thapar, A., 6 Apr 2020, In : Psychological Medicine. p. 1 - 8 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile -
ADHD genetic liability and physical health outcomes - A two-sample Mendelian randomization study
Leppert, B., Riglin, L., Wootton, R. E., Dardani, C., Thapar, A., Staley, J. R., Tilling, K. M., Davey Smith, G., Thapar, A. & Stergiakouli, E., 14 Aug 2020, (Accepted/In press) In : American Journal of Epidemiology.Research output: Contribution to journal › Article (Academic Journal) › peer-review