Research output per year
Research output per year
Research output
- 28 results
Search results
-
2022
Pro-opiomelanocortin neurons in the nucleus of the solitary tract mediate endorphinergic endogenous analgesia in mice
Patra, P., Tench, B. L., Hitrec, T., Holmes, F. E., Drake, R. A. R., Cerritelli, S., Spanswick, D. & Pickering, A. E., 18 Oct 2022, (E-pub ahead of print) In: PAIN.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile3 Citations (Scopus)205 Downloads (Pure) -
2017
Targeted disruption of the orphan receptor Gpr151 does not alter pain-related behaviour despite a strong induction in dorsal root ganglion expression in a model of neuropathic pain
Holmes, F. E., Kerr, N. C. H., Vanderplank, P. A., McArdle, C. & Wynick, D., 1 Jan 2017, In: Molecular and Cellular Neuroscience. 78, p. 35-40 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile16 Citations (Scopus)414 Downloads (Pure) -
2015
Galanin is an autocrine myelin and oligodendrocyte trophic signal induced by leukemia inhibitory factor
Gresle, M. M., Butzkueven, H., Perreau, V. M., Jonas, A., Xiao, J., Thiem, S., Holmes, F. E., Doherty, W., Soo, P.-Y., Binder, M. D., Akkermann, R., Jokubaitis, V. G., Cate, H. S., Marriott, M. P., Gundlach, A. L., Wynick, D. & Kilpatrick, T. J., Jun 2015, In: Glia. 63, 6, p. 1005-1020 16 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile12 Citations (Scopus)455 Downloads (Pure) -
Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity
Lang, R., Gundlach, A. L., Holmes, F. E., Hobson, S., Wynick, D., Hökfelt, T. & Kofler, B., Jan 2015, In: Pharmacological Reviews. 67, 1, p. 118-175 58 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile244 Citations (Scopus)983 Downloads (Pure) -
The generation of knock-in mice expressing fluorescently tagged galanin receptors 1 and 2
Kerr, N. C. H., Holmes, F. E., Hobson, S.-A., Vanderplank, P., Leard, A. D., Balthasar, N. & Wynick, D., Sept 2015, In: Molecular and Cellular Neuroscience. 68, p. 258-271 14 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile13 Citations (Scopus)755 Downloads (Pure) -
2012
Galanin-expression and galanin-dependent sensory neurons are not required for itch
Holmes, F. E., Vanderplank, P. & Wynick, D., 2012, In: Molecular Pain. 8, p. 87Research output: Contribution to journal › Article (Academic Journal) › peer-review
6 Citations (Scopus) -
2011
Axotomy-induced miR-21 promotes axon growth in adult dorsal root ganglion neurons
Strickland, I., Holmes, F., Richards, L., Wynick, D., Uney, J. & Wong, L., 10 Aug 2011, In: PLoS ONE. 6, 8, p. e23423 - e23423 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
147 Citations (Scopus) -
Endogenous Galanin Protects Mouse Hippocampal Neurons Against Amyloid Toxicity in vitro via Activation of Galanin Receptor-2
Elliott-Hunt, C. R., Holmes, F., Hartley, D. M., Perez, S., Mufson, E. J. & Wynick, D., 2011, In: Journal of Alzheimer's disease : JAD. 25(3), p. 455 - 462 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
31 Citations (Scopus) -
Galanin negatively modulates opiate withdrawal via galanin receptor 1
Holmes, F., Armenaki, A., Lismaa, T., Einstein, E., Shine, J., Picciotto, M., Wynick, D. & Zachariou, V., Oct 2011, In: Psychopharmacology.Research output: Contribution to journal › Article (Academic Journal) › peer-review
13 Citations (Scopus) -
2010
Characterisation of the nociceptive phenotype of suppressible galanin overexpressing transgenic mice
Pope, R., Holmes, F., Kerr, N. & Wynick, D., Oct 2010, In: Molecular Pain. 6Research output: Contribution to journal › Article (Academic Journal) › peer-review
13 Citations (Scopus) -
The expression of ELK transcription factors in adult DRG: Novel isoforms, antisense transcripts and upregulation by nerve damage
Kerr, N., Pintzas, A., Holmes, F., Hobson, S., Pope, R., Wallace, M., Wasylyk, C., Wasylyk, B. & Wynick, D., 2010, In: Molecular and Cellular Neuroscience. 44, p. 165 - 177Research output: Contribution to journal › Article (Academic Journal) › peer-review
18 Citations (Scopus) -
2008
Galanin acts as a trophic factor to the central and peripheral nervous systems
Hobson, S., Bacon, A., Elliott-Hunt, C., Holmes, F., Kerr, N., Pope, R., Vanderplank, P. & Wynick, D., 2008, In: Cellular and Molecular Life Sciences. 65, p. 1806 - 1812Research output: Contribution to journal › Article (Academic Journal) › peer-review
51 Citations (Scopus) -
Intra-neural administration of fractalkine attenuates neuropathic pain-related behaviour
Holmes, F., Arnott, N., Vanderplank, P., Kerr, N., Longbrake, E., Popovich, P., Imai, T., Combadiere, C., Murphy, P. & Wynick, D., 2008, In: Journal of Neurochemistry. 106, p. 640 - 649Research output: Contribution to journal › Article (Academic Journal) › peer-review
37 Citations (Scopus) -
Novel mRNA isoforms of the sodium channels Na(v)1.2, Na(v)1.3 and Na(v)1.7 encode predicted two-domain, truncated proteins
Kerr, N., Holmes, F. & Wynick, D., 2008, In: Neuroscience. 155, p. 797 - 808Research output: Contribution to journal › Article (Academic Journal) › peer-review
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2007
Characterization of an enhancer region of the galanin gene that directs expression to the dorsal root ganglion and confers responsiveness to axotomy
Bacon, A., Kerr, N., Holmes, F., Gaston, K. & Wynick, D., Jun 2007, In: Journal of Neuroscience. 27 (24), p. 6573 - 6580 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
27 Citations (Scopus) -
The sodium channel Nav1.5a is the predominant isoform expressed in adult mouse dorsal root ganglia and exhibits distinct inactivation properties from the full-length Nav1.5 channel
Kerr, N., Gao, Z., Holmes, F., Hobson, S., Hancox, J., Wynick, D. & James, A., Jun 2007, In: Molecular and Cellular Neuroscience. 35 (2), p. 283 - 291 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
28 Citations (Scopus) -
2006
Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain-like behaviour
Hobson, S., Holmes, F., Kerr, N., Pope, R. & Wynick, D., Nov 2006, In: Journal of Neurochemistry. 99 (3), p. 1000 - 1010 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
80 Citations (Scopus) -
2005
Use of genetically engineered transgenic mice to investigate the role of galanin in the peripheral nervous system after injury
Holmes, F., Mahoney, S. & Wynick, D., 2005, In: Neuropeptides. 39(3), p. 191 - 199 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
54 Citations (Scopus) -
2004
Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat
Kerr, N., Holmes, F. & Wynick, D., Jun 2004, In: Journal of Biological Chemistry. 279 (23), p. 24826 - 24833 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
47 Citations (Scopus) -
2003
The second galanin receptor GalR2 plays a key role in neurite outgrowth from adult sensory neurons
Mahoney, S., Hosking, R., Farrant, S., Holmes, F., Jacoby, A., Shine, J., Iismaa, T., Scott, M., Schmidt, R. & Wynick, D., Jan 2003, In: Journal of Neuroscience. 23 (2), p. 416 - 421 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
129 Citations (Scopus) -
Transgenic overexpression of galanin in the dorsal root ganglia modulates pain-related behavior
Holmes, F., Bacon, A., Pope, R., Vanderplank, P., Kerr, N., Sukumaran, M., Pachnis, V. & Wynick, D., 13 May 2003, In: Proceedings of the National Academy of Sciences of the United States of America. 100 (10), p. 6180 - 6185 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
67 Citations (Scopus) -
2002
Phenotypic analysis of Galr1 knockout mice reveals a role for GALR1 galanin receptor in modulating seizure activity but not nerve regeneration
Jacoby, A., Holmes, F., Hort, Y., Shine, J. & Iismaa, T., 2002, In: Letters in Peptide Science. 8, p. 139 - 146Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Transgenic over-expression of galanin in injured primary sensory neurons
Bacon, A., Holmes, F., Small, C., Ghatei, M., Mahoney, S., Bloom, S. & Wynick, D., Nov 2002, In: NeuroReport. 13 (16), p. 2129 - 2132 4 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
24 Citations (Scopus) -
2000
Galanin-like peptide (GALP) is expressed in rat hypothalamus and pituitary, but not in DRG
Kerr, N., Holmes, F. & Wynick, D., 2000, In: NeuroReport. 11, p. 3909 - 3913 17.Research output: Contribution to journal › Article (Academic Journal) › peer-review
68 Citations (Scopus) -
Galanin regulates the post-natal survival of a sub-set of basal forebrain cholinergic neurons
O'Meara, G., Coumis, U., Ma, S., Kehr, J., Mahoney, S., Bacon, A., Allen, S., Holmes, F., Kahl, U., Wang, F., Kearns, I., Ove-Ogren, S., Dawbarn, D., Mufson, E., Davies, C., Dawson, G. & Wynick, D., 2000, In: Proceedings of the National Academy of Sciences of the United States of America. 97, p. 11569 - 11574Research output: Contribution to journal › Article (Academic Journal) › peer-review
106 Citations (Scopus) -
Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity
Holmes, F., Mahoney, S., King, V., Bacon, A., Kerr, N., Pachnis, V., Curtis, R., Priestley, J. & Wynick, D., 2000, In: Proceedings of the National Academy of Sciences of the United States of America. 97, p. 11563 - 11568Research output: Contribution to journal › Article (Academic Journal) › peer-review
185 Citations (Scopus) -
1998
Galanin regulates prolactin release and lactotroph proliferation
Wynick, D., Small, C., Bacon, A., Holmes, F., Norman, M., Ormandy, C., Kilic, E., Kerr, N., Ghatei, M., Talamantes, F., Bloom, S. & Pachnis, V., 1998, In: Proceedings of the National Academy of Sciences of the United States of America. 95, p. 12671 - 12676Research output: Contribution to journal › Article (Academic Journal) › peer-review
180 Citations (Scopus) -
1995
Trophic control of survival and proliferation in cultured rat embryo forebrain germinal cells by α-adrenoreceptors
Brennan, H., Muxworthy, A., Vignes, A., Pabbathi, V., Holmes, F. & Haynes, L., 1995, In: Journal of Physiology. 487Research output: Contribution to journal › Article (Academic Journal) › peer-review