Professor Gianni D Angelini

M.D.(Sienna), M.Ch.(Wales), F.R.C.S.(Glas), FETCS

  • BS2 8HW

1992 …2020

Research output per year

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Research Output

2018

Predictors of survival in octogenarians after mitral valve surgery for degenerative disease: The Mitral Surgery in Octogenarians study

Chivasso, P., Bruno, V. D., Farid, S., Malvindi, P. G., Modi, A., Benedetto, U., Ciulli, F., Abu-Omar, Y., Caputo, M., Angelini, G. D., Livesey, S. & Vohra, H. A., Apr 2018, In : Journal of Thoracic and Cardiovascular Surgery. 155, 4, p. 1474-1482.e2 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
6 Citations (Scopus)
170 Downloads (Pure)

Preoperative renal impairment and off-pump coronary artery bypass grafting: The jury is still out

Zakkar, M. & Angelini, G. D., Sep 2018, In : Journal of Thoracic and Cardiovascular Surgery. 156, 3, p. 974-975 2 p.

Research output: Contribution to journalEditorial (Academic Journal)

1 Citation (Scopus)

Primary repair versus surgical and transcatheter palliation in infants with tetralogy of Fallot

Dorobantu, D. M., Mahani, A. S., Sharabiani, M. T. A., Pandey, R., Angelini, G. D., Parry, A. J., Tulloh, R. M. R., Martin, R. P. & Stoica, S. C., Nov 2018, In : Heart. 104, 22, p. 1864-1870 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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6 Citations (Scopus)
231 Downloads (Pure)

Propensity-matched analysis of outcomes after mitral valve surgery between trainees and consultants (institutional report)

Bruno, V. D., Chivasso, P., Hayat, A., Marsico, R., Benedetto, U., Caputo, M., Ascione, R., Angelini, G. D., Ciulli, F. & Vohra, H. A., 1 Mar 2018, In : Interactive Cardiovascular and Thoracic Surgery. 26, 3, p. 443-447 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
210 Downloads (Pure)

Prophylactic corticosteroids for paediatric heart surgery with cardiopulmonary bypass

Gibbison, B., Villalobos Lizardi, J. C., Avilés Martínez, K. I., Fudulu, D. P., Medina Andrade, M. A., Pérez-Gaxiola, G., Schadenberg, A. W. L., Stoica, S. C., Lightman, S. L., Angelini, G. D. & Reeves, B. C., 30 Aug 2018, In : Cochrane Database of Systematic Reviews. 2018, 8, 14 p., CD013101.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
110 Downloads (Pure)

Radial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery

Gaudino, M., Benedetto, U., Angelini, G. D. & RADIAL Investigators, 31 May 2018, In : New England Journal of Medicine. 378, 22, p. 2069-2077 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
387 Downloads (Pure)

Safety of Perioperative Aprotinin Administration During Isolated Coronary Artery Bypass Graft Surgery: Insights From the ART (Arterial Revascularization Trial)

Benedetto, U., Altman, D. G., Gerry, S., Gray, A., Lees, B., Angelini, G. D., Flather, M., Taggart, D. P. & On behalf of the ART (Arterial Revascularization Trial) Investigators, 6 Mar 2018, In : Journal of the American Heart Association. 7, 5, 15 p., e007570.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
207 Downloads (Pure)

Statistical primer: Propensity score matching and its alternatives

Benedetto, U., Head, S. J., Angelini, G. D. & Blackstone, E. H., 1 Jun 2018, In : European Journal of Cardio-Thoracic Surgery. 53, 6, p. 1112-1117 6 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
29 Citations (Scopus)
176 Downloads (Pure)

Surgery for Young Adults With Aortic Valve Disease not Amenable to Repair

Zakkar, M., Bruno, V. D., Visan, A. C., Curtis, S., Angelini, G., Lansac, E. & Stoica, S., 2 Mar 2018, In : Frontiers in Surgery. 5, 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
146 Downloads (Pure)

Transplantation of allogeneic pericytes improves myocardial vascularization and reduces interstitial fibrosis in a swine model of reperfused acute myocardial infarction

Alvino, V. V., Fernandez-Jimenez, R., Rodriguez-Arabaolaza, I., Slater, S., Mangialardi, G., Avolio, E., Spencer, H., Culliford, L., Hassan, S., Sueiro Ballesteros, L., Herman, A., Ayaon-Albarran, A., Galan-Arriola, C., Sanchez-Gonzalez, J., Hennessey, H., Delmege, C., Ascione, R., Emanueli, C., Angelini, G., Ibanez, B. & 1 others, Madeddu, P., Jan 2018, In : Journal of the American Heart Association. 7, 2, 43 p., e006727.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
11 Citations (Scopus)
285 Downloads (Pure)

Vasopressors During Cardiopulmonary Resuscitation. A Network Meta-Analysis of Randomized Trials.

Belletti, A., Benedetto, U., Putzu, A., Martino, E. A., Biondi-Zoccai, G., Angelini, G. D., Zangrillo, A. & Landoni, G., 1 May 2018, In : Critical Care Medicine. 46, 5, p. e443-e451 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
180 Downloads (Pure)
2017

Activation and inflammation of the venous endothelium in vein graft disease

Ward, A. O., Caputo, M., Angelini, G. D., George, S. J. & Zakkar, M., 24 Aug 2017, In : Atherosclerosis.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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12 Citations (Scopus)
298 Downloads (Pure)
Open Access
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4 Citations (Scopus)
211 Downloads (Pure)
Open Access
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181 Downloads (Pure)

Corticosteroids in septic shock: a systematic review and network meta-analysis

Gibbison, B., Lopez-Lopez, J. A., Higgins, J., Miller, T., Angelini, G., Lightman, S. & Annane, D., 28 Mar 2017, In : Critical Care. 21, 1, 3 p., 78.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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43 Citations (Scopus)
327 Downloads (Pure)

Diagnostic and therapeutic medical devices for safer blood management in cardiac surgery; systematic reviews, observational studies and randomised controlled trials

Murphy, GJ., Mumford, A., Rogers, C. A., Wordsworth, S., Stokes, E., Verheyden, V., Kumar, T., Harris, J. M., Clayton, G. L., Ellis, L. A., Plummer, Z., Dott, W., Serrano, GF., Wozniak, M., Nath, M., Sterne, J., Angelini, G. & Reeves, B., 1 Sep 2017, In : Health Services and Delivery Research. 5, 17, 454 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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355 Downloads (Pure)

Erratum to: Methods for evaluating medical tests and biomarkers

STREAMLINE COLON Investigators, 30 Mar 2017, In : Diagnostic and Prognostic Research. 1, p. 11

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
19 Downloads (Pure)

How safe is it to train residents to perform coronary surgery with multiple arterial grafting? Nineteen years of training at a single institution

Benedetto, U., Caputo, M., Gaudino, M., Vohra, H., Chivasso, P., Bryan, A. & Angelini, G. D., Apr 2017, In : Seminars in Thoracic and Cardiovascular Surgery. 29, 1, p. 12-22 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
265 Downloads (Pure)

Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis

Beltrami, C., Besnier, M., Shantikumar, S., Shearn, A. I. U., Rajakaruna, C., Laftah, A., Sessa, F., Spinetti, G., Petretto, E., Angelini, G. D. & Emanueli, C., 1 Mar 2017, In : Molecular Therapy. 25, 3, p. 679–693 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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62 Citations (Scopus)
428 Downloads (Pure)

Is the right internal thoracic artery superior to saphenous vein for grafting the right coronary artery? A propensity score based analysis

Benedetto, U., Caputo, M., Gaudino, M., Mariscalco, G., Bryan, A. & Angelini, G. D., 22 May 2017, In : Journal of Thoracic and Cardiovascular Surgery. 154, 4, p. 1269-1275.e5 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
8 Citations (Scopus)
191 Downloads (Pure)

Long-term survival after off-pump versus on-pump coronary artery bypass graft surgery. Does completeness of revascularization play a role?

Benedetto, U., Caputo, M., Patel, N. N., Fiorentino, F., Bryan, A. & Angelini, G. D., 9 May 2017, In : International Journal of Cardiology. 246, p. 32-36 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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9 Citations (Scopus)
207 Downloads (Pure)
Open Access
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9 Citations (Scopus)
226 Downloads (Pure)

Minimally invasive aortic valve replacement in high risk patient groups

Fudulu, D., Lewis, H., Benedetto, U., Caputo, M., Angelini, G. D. & Vohra, H., 11 Jun 2017, In : Journal of Thoracic Disease. 25 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
10 Citations (Scopus)
252 Downloads (Pure)

Modulating MicroRNAs in Cardiac Surgery Patients: Novel Therapeutic Opportunities?

Biglino, G., Caputo, M., Rajakaruna, C., Angelini, G., van Rooij, E. & Emanueli, C., Feb 2017, In : Pharmacology and Therapeutics. 170, p. 192-204 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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8 Citations (Scopus)
268 Downloads (Pure)

Myocardial Infarction With Nonobstructed Coronary Arteries: Impact of CMR Early After Presentation

Dastidar, A. G., Rodrigues, J. C. L., Johnson, T. W., De Garate, E., Singhal, P., Baritussio, A., Scatteia, A., Strange, J., Nightingale, A. K., Angelini, G. D., Baumbach, A., Delgado, V. & Bucciarelli-Ducci, C., 18 Jan 2017, In : JACC: Cardiovascular Imaging.

Research output: Contribution to journalEditorial (Academic Journal)

Near-patient coagulation testing to predict bleeding after cardiac surgery: a cohort study

Mumford, A. D., Harris, J., Plummer, Z., Lee, K., Verheyden, V., Reeves, B. C., Rogers, C. A., Angelini, G. D. & Murphy, G. J., Oct 2017, In : Research and Practice in Thrombosis and Haemostasis. 1, 2, p. 242-251 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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258 Downloads (Pure)

Off- vs. on-pump coronary artery bypass graft surgery on hospital outcomes in 134,117 octogenarians

Benedetto, U., Angelini, G. D., Caputo, M., Feldman, D. N., Kim, L. K., Lau, C., Di Franco, A., Girardi, L. N. & Gaudino, M., 1 Dec 2017, In : Journal of Thoracic Disease. 9, 12, p. 5085-5092 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
5 Citations (Scopus)

Optimal Sampling Frequency of Serum Cortisol Concentrations After Cardiac Surgery

Powell, B., Nason, G. P., Angelini, G. D., Lightman, S. L. & Gibbison, B., Oct 2017, In : Critical Care Medicine. 45, 10, p. e1103-e1104 2 p.

Research output: Contribution to journalComment/debate (Academic Journal)

Open Access
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5 Citations (Scopus)
254 Downloads (Pure)

Out of Hospital Cardiac Arrest Survivors with Inconclusive Coronary Angiogram: Impact of Cardiovascular Magnetic Resonance on Clinical Management and Decision-Making

Baritussio, A., Zorzi, A., Ghosh Dastidar, A., Susana, A., Mattesi, G., Rodrigues, J. C. L., Biglino, G., Scatteia, A., De Garate, E., Strange, J., Cacciavillani, L., Iliceto, S., Nisbet, A., Angelini, G. D., Corrado, D., Perazzolo Marra, M. & Bucciarelli-Ducci, C., Jul 2017, In : Resuscitation. 116, p. 91-97 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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5 Citations (Scopus)
181 Downloads (Pure)

Randomized trial of near-infrared spectroscopy for personalized optimization of cerebral tissue oxygenation during cardiac surgery

Rogers, C. A., Stoica, S., Ellis, L., Stokes, E. A., Wordsworth, S., Dabner, L., Clayton, G., Downes, R., Nicholson, E., Bennett, S., Angelini, G. D., Reeves, B. C. & Murphy, G. J., 2017, In : British Journal of Anaesthesia. 119, 3, p. 384-393 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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31 Citations (Scopus)
242 Downloads (Pure)

Remote ischemic preconditioning triggers changes in autonomic nervous system activity: implications for cardioprotection

Abdul-Ghani, S., Fleishman, A. N., Khaliulin, I., Meloni, M., Angelini, G. D. & Suleiman, M-S., 13 Feb 2017, In : Physiological Reports. 5, 3

Research output: Contribution to journalArticle (Academic Journal)

Open Access
10 Citations (Scopus)

Right internal thoracic artery or radial artery? A propensity matched comparison on the second best arterial conduit

Benedetto, U., Caputo, M., Gaudino, M., Marsico, R., Rajakaruna, C., Bryan, A. & Angelini, G. D., Jan 2017, In : Journal of Thoracic and Cardiovascular Surgery. 153, 1, p. 79–88.e4 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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13 Citations (Scopus)
242 Downloads (Pure)
Open Access
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1 Citation (Scopus)
408 Downloads (Pure)

The adipokine leptin modulates adventitial pericyte functions by autocrine and paracrine signalling

Riu, F., Slater, S. C., Garcia, E. J., Rodriguez-Arabaolaza, I., Alvino, V., Avolio, E., Mangialardi, G., Cordaro, A., Satchell, S., Zebele, C., Caporali, A., Angelini, G. & Madeddu, P., 14 Jul 2017, In : Scientific Reports. 7, 13 p., 5443.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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5 Citations (Scopus)
397 Downloads (Pure)

The effect of vasoactive drugs on mortality in patients with severe sepsis and septic shock: A network meta-analysis of randomized trials

Belletti, A., Benedetto, U., Biondi-Zoccai, G., Leggieri, C., Silvani, P., Angelini, G. D., Zangrillo, A. & Landoni, G., Feb 2017, In : Journal of Critical Care. 37, p. 91-98 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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16 Citations (Scopus)
272 Downloads (Pure)

The effects of preoperative volume replacement in diabetic patients undergoing coronary artery bypass grafting surgery: protocol for a randomised controlled trial (VeRDiCT trial)

Clout, M., Harris, T. L., Rogers, C., Culliford, L., Taylor, J., Angelini, G., Narayan, P., Reeves, B., Hillier, J., Ashton, K., Sarkar, K. & Ascione, R., 19 Jun 2017, In : JMIR Research Protocols. 6, 6, 10 p., e119.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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176 Downloads (Pure)
2016
Open Access
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17 Citations (Scopus)
414 Downloads (Pure)

Aortic stenosis: diagnosis and management

Zakkar, M., Bryan, A. J. & Angelini, G. D., 19 Oct 2016, In : BMJ. 355, 9 p., i5425.

Research output: Contribution to journalArticle (Academic Journal)

11 Citations (Scopus)

Aortic Valve Replacement and the Ross Operation in Children and Young Adults

Sharabiani, M. T. A., Dorobantu, D. M., Mahani, A. S., Turner, M., Peter Tometzki, A. J., Angelini, G. D., Parry, A. J., Caputo, M. & Stoica, S. C., 21 Jun 2016, In : Journal of the American College of Cardiology. 67, 24, p. 2858-2870 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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44 Citations (Scopus)
202 Downloads (Pure)

Are lower levels of red blood cell transfusion more cost-effective than liberal levels after cardiac surgery? Findings from the TITRe2 randomised controlled trial

Stokes, E. A., Wordsworth, S., Bargo, D., Pike, K., Rogers, C. A., Brierley, R. C. M., Angelini, G. D., Murphy, G. J., Reeves, B. C. & TITRe2 Investigators, Aug 2016, In : BMJ Open. 6, 8, 10 p., e011311.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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10 Citations (Scopus)
287 Downloads (Pure)
Open Access
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20 Citations (Scopus)
181 Downloads (Pure)

A Role for the Long Noncoding RNA SENCR in Commitment and Function of Endothelial Cells

Boulberdaa, M., Scott, E., Ballantyne, M., Garcia, R., Descamps, B., Angelini, G. D., Brittan, M., Hunter, A., McBride, M., McClure, J., Miano, J. M., Emanueli, C., Mills, N. L., Mountford, J. C. & Baker, A. H., May 2016, In : Molecular Therapy. 24, 5, p. 978-990 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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76 Citations (Scopus)
291 Downloads (Pure)

A time-series study of percutaneous closure of patent foramen ovale: premature adoption?

Lew, K. N., Angelini, G. D. & Hollingworth, W., Jan 2016, In : Open Heart. 3, 1, 9 p., e000313.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
162 Downloads (Pure)

Chronic hypoxia downregulates ZO-2 expression in children with cyanotic congenital heart defect

Jenkins, E. L., Caputo, M., Angelini, G. D. & Ghorbel, M., Jun 2016, In : ESC Heart Failure. 3, 2, p. 131-137 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
198 Downloads (Pure)

Coronary Artery-Bypass-Graft Surgery Increases the Plasma Concentration of Exosomes Carrying a Cargo of Cardiac MicroRNAs: An Example of Exosome Trafficking Out of the Human Heart with Potential for Cardiac Biomarker Discovery

Emanueli, C., Shearn, A. I. U., Laftah, A., Fiorentino, F., Reeves, B. C., Beltrami, C., Mumford, A., Clayton, A., Gurney, M., Shantikumar, S. & Angelini, G. D., 29 Apr 2016, In : PLoS ONE. 11, 4, 21 p., e0154274.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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43 Citations (Scopus)
348 Downloads (Pure)

Coronary surgery is superior to drug eluting stents in multivessel disease. Systematic review and meta-analysis of contemporary randomized controlled trials

Benedetto, U., Gaudino, M., Ng, C., Biondi-Zoccai, G., D'Ascenzo, F., Frati, G., Girardi, L. N., Angelini, G. D. & Taggart, D. P., 1 May 2016, In : International Journal of Cardiology. 210, p. 19-24 6 p.

Research output: Contribution to journalArticle (Academic Journal)

18 Citations (Scopus)

Current outcomes of off-pump versus on-pump coronary artery bypass grafting: evidence from randomized controlled trials

Fudulu, D., Benedetto, U., Pecchinenda, G. G., Chivasso, P., Bruno, V. D., Rapetto, F., Bryan, A. & Angelini, G. D., 14 Nov 2016, In : Journal of Thoracic Disease. 8, Suppl 10, p. S758-S771 14 p.

Research output: Contribution to journalArticle (Academic Journal)

12 Citations (Scopus)

Early Reoperations in a 5-Year National Cohort of Pediatric Patients With Congenital Heart Disease

Fiorentino, F., Stickley, J., Dorobantu, D., Pandey, R., Angelini, G., Barron, D. & Stoica, S., Apr 2016, In : Annals of Thoracic Surgery. 101, 4, p. 1522-9 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Impact of multiple arterial grafts in off-pump and on-pump coronary artery bypass surgery

Benedetto, U., Caputo, M., Angelini, G., Bryan, A., Gaudino, M. & Mariscalco, G., 16 Nov 2016, In : Journal of Thoracic and Cardiovascular Surgery. 153, 2, p. 300-309 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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6 Citations (Scopus)
249 Downloads (Pure)

Impact of off-pump coronary artery bypass grafting on survival: current best available evidence

Chivasso, P., Guida, G. A., Fudulu, D., Bruno, V. D., Marsico, R., Sedmakov, H., Zakkar, M., Rapetto, F., Bryan, A. J. & Angelini, G. D., 1 Nov 2016, In : Journal of Thoracic Disease. 8, Suppl 10, p. S808-S817 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
6 Citations (Scopus)
124 Downloads (Pure)