Personal profile
Research interests
Golam Khandaker is Professor of Psychiatry at Bristol Medical School, Head of Immunopsychiatry and Experimental Medicine Programme at the MRC Integrative Epidemiology Unit, and Honorary Consultant Psychiatrist at the Avon and Wiltshire Mental Health Parthership NHS Trust. Golam's research focuses on identifying and validating novel immunological mechanisms and potential treatment targets for major psychiatric disorders particularly depression and schizophrenia using epidemiological cohort studies, genetic analysis, and early-phase clinical trials. The key impetus for this work is to move immunotherapies closer to psychiatric practice through innovative translational research. He is also interested in life-course epidemiology of mental disorders, physical and psychiatric multimorbidity especially aetiology, early detection, and prevention of cardiometabolic disease in people with schiozophrenia and depression, and use of routine clinical data for health research.
External positions
Wellcome Trust Clinical Fellow, University of Cambridge
1 Jan 2017 → 31 Dec 2021
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Collaborations and top research areas from the last five years
Research output
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Neurodevelopmental copy number variants increase risk of internalising and cardiometabolic multimorbidity: findings from UK Biobank
Katzourou, I. K., LINC consortium, Barroso, I., Clayton, J., Khandaker, G., Stow, D., Timpson, N. J., Tsang, R., Underwood, J., Wood, M., Kirov, G., Walters, J., Owen, M. J., Holmans, P. & van den Bree, M. B. M., 26 Feb 2026, (Accepted/In press) In: American Journal of Human Genetics.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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The genetic architecture of postoperative delirium after major surgery and its relationship with non-postoperative neurocognitive conditions: A genome-wide association study
Armstrong, R., Yousefi, P. D., Gibbison, B., Khandaker, G. & Gaunt, T. R., 2 Mar 2026, In: PLOS Medicine. 23, 3, 15 p., e1004963.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Antidepressant prescribing trends for autistic adults with and without intellectual disabilities in England from 1997 to 2023, a population-based cohort study
Sadik, A. A. S., Khandaker, G., Pardinas, A., Madley-Dowd, P. C. & Rai, D., 29 Jul 2025.Research output: Contribution to conference › Conference Poster
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The South Wales and South West England Mental Health Platform Hub
Khandaker, G. (Principal Investigator)
1/04/24 → 31/03/29
Project: Research
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CHECKPOINT: Finding immune and metabolic pathways to severe mental illness
Khandaker, G. (Principal Investigator)
1/04/24 → 31/03/29
Project: Research
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8073 MRC IEU - Tim Larsen consumables
Khandaker, G. (Principal Investigator)
18/09/23 → 1/10/27
Project: Research
Datasets
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Postoperative complications GWAS summary statistics
Armstrong, R. (Creator), Yousefi, P. (Contributor), Gibbison, B. (Contributor), Khandaker, G. (Contributor) & Gaunt, T. (Contributor), University of Bristol, 20 Mar 2026
DOI: 10.5523/bris.2qwk57ww5i25420f0sm64r7r3f, http://data.bris.ac.uk/data/dataset/2qwk57ww5i25420f0sm64r7r3f
Dataset
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Postoperative delirium GWAS summary statistics
Armstrong, R. (Creator), Yousefi, P. (Contributor), Gibbison, B. (Contributor), Khandaker, G. (Contributor) & Gaunt, T. (Contributor), University of Bristol, 19 Feb 2026
DOI: 10.5523/bris.1m83zai2e26yq2lro3tixz9kqq, http://data.bris.ac.uk/data/dataset/1m83zai2e26yq2lro3tixz9kqq
Dataset