Miss Grace Young

Research Output

Research Output per year

2015 2020

• 26 Article (Academic Journal)
• 1 Conference Contribution (Conference Proceeding)
• 1 Other contribution

Research Output per year

Research Output per year

Search results

• 2020

  Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT

  Hamdy, F. C., Donovan, J. L., Lane, J. A., Mason, M., Metcalfe, C., Holding, P., Wade, J., Noble, S., Garfield, K., Young, G., Davis, M., Peters, T. J., Turner, E. L., Martin, R. M., Oxley, J., Robinson, M., Staffurth, J., Walsh, E., Blazeby, J., Bryant, R. & 16 others, Bollina, P., Catto, J., Doble, A., Doherty, A., Gillatt, D., Gnanapragasam, V., Hughes, O., Kockelbergh, R., Kynaston, H., Paul, A., Paez, E., Powell, P., Prescott, S., Rosario, D., Rowe, E. & Neal, D., 28 Jul 2020, (Accepted/In press) In : Health technology assessment (Winchester, England). 24, 37, p. 1-176 176 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Prostatectomy
  • Prostatic Neoplasms
  • Radiotherapy
  • Confidence Intervals
  • Prostate-Specific Antigen
  51 Downloads (Pure)

• Diagnostic Assessment of Lower Urinary Tract Symptoms in Men Considering Prostate Surgery: A Noninferiority Randomised Controlled Trial of Urodynamics in 26 Hospitals

  Drake, M. J., Lewis, A. L., Young, G., Abrams, P. H., Blair, P. S., Chapple, C., Glazener, C., Horwood, J. P., McGrath, J., Noble, S. M., Taylor, G. & Lane, J. A., 1 Nov 2020, In : European Urology. 78, 5, p. 701-710 10 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Lower Urinary Tract Symptoms
  • Urodynamics
  • Prostate
  • Randomized Controlled Trials
  • Urinary Bladder Neck Obstruction

• Drainage, Irrigation And Fibrinolytic Therapy (Drift) For Post-Haemorrhagic Ventricular Dilatation: 10-Year Follow-Up Of A Randomised Controlled Trial

  Luyt, K., Jary, S. L., Lea, C. L., Young, G. J., Odd, D. E., Miller, H. E., Kmita, G., Williams, C., Blair, P. S., Hollingworth, W., Morgan, M., Smith-Collins, A. P., Walker-Cox, S., Aquilina, K., Pople, I. & Whitelaw, A. G., 4 Jul 2020, In : Archives of Disease in Childhood: Fetal and Neonatal Edition. 8 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Thrombolytic Therapy
  • Drainage
  • Dilatation
  • Randomized Controlled Trials
  • Hemorrhage
  23 Downloads (Pure)

• Economic evaluation of the OSAC randomised controlled trial: oral corticosteroids for non-asthmatic adults with acute lower respiratory tract infection in primary care

  Moure-Fernandez, A., Hollinghurst, S., Carroll, F. E., Downing, H., Young, G., Brookes, S., May, M., Hay, A. D. & al., E., 18 Feb 2020, In : BMJ Open. 10, 2, 8 p., e033567.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Respiratory Tract Infections
  • Cost-Benefit Analysis
  • Adrenal Cortex Hormones
  • Primary Health Care
  • Randomized Controlled Trials
  51 Downloads (Pure)

• Grading severity and bother using the IPSS and ICIQ-MLUTS scores in men seeking lower urinary tract symptoms therapy

  Ito, H., Young, G., Lewis, A. L., Blair, P. S., Cotterill, N., Lane, A. A., Sakamaki, K., Drake, M. J. & Abrams, P., 29 May 2020, In : The Journal of urology.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Lower Urinary Tract Symptoms
  • Prostate
  • Quality of Life
  • Patient Reported Outcome Measures
  • ROC Curve

• Oral prednisolone for acute lower respiratory tract infection in clinically unrecognised asthma: an exploratory analysis of the Oral Steroids for Acute Cough (OSAC) randomised trial

  Hawkey, S., Young, G. J., Little, P., Moore, M. & Hay, A. D., 3 Nov 2020, In : British Journal of General Practice Open. 13 p., bjgpopen20X101099.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Prednisolone
  • Cough
  • Respiratory Tract Infections
  • Asthma
  • Steroids
  13 Downloads (Pure)

• Ten-year mortality, disease progression and treatment-related side-effects in men with localised prostate cancer from the ProtecT randomised controlled trial according to treatment received

  Neal, D. E., Metcalfe, C., Donovan, J. L., Lane, J. A., Davis, M. J., Young, G. J., Dutton, S. J., Walsh, E. I., Martin, R. M., Peters, T. J., Turner, E. L., Mason, M., Bollina, P., Catto, J., Doherty, A., Gillatt, D., Gnanapragasam, V., Holding, P., Hughes, O., Kockelbergh, R. & 9 others, Kynaston, H., Oxley, J., Paul, A., Paez, E., Rosario, D. J., Rowe, E., Staffurth, J., Altman, D. G. & Hamdy, F. C., 1 Mar 2020, In : European Urology. 77, 3, p. 320-330 11 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Disease Progression
  • Prostatic Neoplasms
  • Randomized Controlled Trials
  • Mortality
  • Radiotherapy
  401 Downloads (Pure)

• The Cost-Effectiveness of Transurethral resection of the prostate versus Thulium laser transurethral vaporesection of the prostate in the UNBLOCS randomised controlled trial for benign prostatic obstruction

  Noble, S. M., Ahern, A. M., Worthington, J. M., Hashim, H., Taylor, H. J., Young, G., Sara, B., Abrams, P. H., Johnson, L., Khan, R., Page, T., Swami, S. & Lane, J. A., 10 Aug 2020, In : BJU International. 9 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Thulium
  • Transurethral Resection of Prostate
  • Cost-Benefit Analysis
  • Lasers
  • Randomized Controlled Trials
  16 Downloads (Pure)

• The ProtecT trial: analysis of the patient cohort, baseline risk stratification and disease progression

  Bryant, R. J., Oxley, J., Young, G. J., Lane, J. A., Metcalfe, C., Davis, M., Turner, E. L., Martin, R. M., Goepel, J. R., Varma, M., Griffiths, D. F., Grigor, K., Mayer, N., Warren, A. Y., Bhattarai, S., Dormer, J., Mason, M., Staffurth, J., Walsh, E., Rosario, D. J. & 16 others, F Catto, J. W., Neal, D. E., Donovan, J. L., Hamdy, F. C., Bollina, P., Doble, A., Doherty, A., Gillatt, D., Gnanapragasam, V., Hughes, O., Kockelbergh, R., Kynaston, H., Paul, A., Paez, E., Rowe, E. & the ProtecT Study Group, 12 Feb 2020, In : BJU International. 9 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Disease Progression
  • Prostatic Neoplasms
  • Cohort Studies
  • Therapeutics
  • Prostatectomy
  76 Downloads (Pure)

• Thulium laser transurethral VApoResection of the Prostate (ThuVARP) versus TransUrethral Resection of the Prostate (TURP) in men with lower urinary tract symptoms or urinary retention secondary to benign prostatic obstruction: A randomised controlled trial

  Hashim, H., Worthington, J., Abrams, P., Young, G., Taylor, H., Noble, S. M., Brookes, S. T., Cotterill, N., Page, T., Swami, K. S. & Lane, J. A., 4 Jul 2020, In : The Lancet. 396, 10243, p. 50-61 12 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Thulium
  • Transurethral Resection of Prostate
  • Lower Urinary Tract Symptoms
  • Urinary Retention
  • Lasers
  17 Downloads (Pure)

• Thulium laser transurethral vaporesection versus transurethral resection of the prostate for benign prostatic obstruction: the UNBLOCS RCT

  Worthington, J. M., Lane, J. A., Taylor, H. J., Young, G., Noble, S. M., Abrams, P. H., Ahern, A. M., Brookes, S. T., Cotterill, N., Johnson, L., Khan, R., Moure-Fernandez, A., Page, T., Swami, K. S. & Hashim, H., 10 Sep 2020, In : Health Technology Assessment. 24, 41

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Thulium
  • Transurethral Resection of Prostate
  • Lasers
  • Prostate
  • Confidence Intervals
  12 Downloads (Pure)

• Urodynamics tests for the diagnosis and management of bladder outlet obstruction in men: the UPSTREAM non-inferiority RCT

  Lewis, A. L., Young, G. J., Selman, L. E., Rice, C., Clement, C., Ochieng, C. A., Abrams, P., Blair, P. S., Chapple, C., Glazener, C. M. A., Horwood, J., McGrath, J. S., Noble, S., Taylor, G. T., Lane, J. A. & Drake, M. J., 9 Sep 2020, In : Health Technology Assessment. 24, 42, p. 1-154 154 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Urinary Bladder Neck Obstruction
  • Urodynamics
  • Underactive Urinary Bladder
  • Random Allocation
  • Prostate
  19 Downloads (Pure)
• 2019

  Anaesthetic–analgesic ear drops to reduce antibiotic consumption in children with acute otitis media: the CEDAR RCT

  Hay, A. D., Downing, H., Francis, N. A., Young, G. J., Clement, C., Harris, S. D., Ahern, A., Schofield, B., Thomas, T. E., Horwood, J., Blair, P. S., Hollingworth, W., Wilson, V., Metcalfe, C., Stoddart, P., Nunez, D., Lyttle, M. D., Little, P. & Moore, M. V., 3 Jul 2019, In : Health Technology Assessment. 23, 34, p. 1-48 48 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Otitis Media
  • Ear
  • Anti-Bacterial Agents
  • Child
  • Pain
  1 Citation (Scopus)

  188 Downloads (Pure)

• Clinical and Patient-reported Outcome Measures in Men Referred for Consideration of Surgery to Treat Lower Urinary Tract Symptoms: Baseline Results and Diagnostic Findings of the Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM)

  Lewis, A. L., Young, G. J., Abrams, P., Blair, P. S., Chapple, C., Glazener, C. M. A., Horwood, J., McGrath, J. S., Noble, S., Taylor, G. T., Ito, H., Belal, M., Davies, M. C., Dickinson, A. J., Foley, C. L., Foley, S., Fulford, S., Gammal, M. M., Garthwaite, M., Harris, M. R. E. & 23 others, Ilie, P. C., Jones, R., Sabbagh, S., Mason, R. G., McLarty, E., Mishra, V., Mom, J., Morley, R., Natale, S., Nitkunan, T., Page, T., Payne, D., Rashid, T. G., Saeb-Parsy, K., Sandhu, S. S., Simoes, A., Singh, G., Sullivan, M., Tempest, H. V., Viswanath, S., Walker, R. M. H., Lane, J. A. & Drake, M. J., 1 May 2019, In : European Urology Focus. 5, 3, p. 340-350 11 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Lower Urinary Tract Symptoms
  • Urodynamics
  • Patient Reported Outcome Measures
  • Prostate
  • Nocturia
  11 Citations (Scopus)

  110 Downloads (Pure)

• Factors associated with trial recruitment, preferences, and treatments received were elucidated in a comprehensive cohort study

  Donovan, J., Opmeer, B., Young, G., Mills, N., Martin, R., Lane, J. A., Metcalfe, C., Peters, TJ., Davis, M., Turner, E., Walsh, E., Neal, D., Hamdy, F. C. & the ProtecT Study Group, 1 Sep 2019, In : Journal of Clinical Epidemiology. 113, p. 200-213 14 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Cohort Studies
  • Prostatic Neoplasms
  • Random Allocation
  • Patient Preference
  • boldenone undecylenate
  1 Citation (Scopus)

  170 Downloads (Pure)

• Ten-year follow-up of a randomised trial of drainage, irrigation and fibrinolytic therapy (DRIFT) in infants with post-haemorrhagic ventricular dilatation

  Luyt, K., Jary, S., Lea, C., Young, G. J., Odd, D., Miller, H., Kmita, G., Williams, C., Blair, P. S., Fernández, A. M., Hollingworth, W., Morgan, M., Smith-Collins, A., Thai, N. J., Walker-Cox, S., Aquilina, K., Pople, I. & Whitelaw, A., 1 Feb 2019, In : Health Technology Assessment. 23, 4, p. 1-116 116 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Thrombolytic Therapy
  • Drainage
  • Dilatation
  • Confidence Intervals
  • Cost-Benefit Analysis
  10 Citations (Scopus)

  257 Downloads (Pure)
• 2018

  A prospective cohort and extended comprehensive-cohort design provided insights about the generalizability of a pragmatic trial: the ProtecT prostate cancer trial

  Donovan, J. L., Young, G. J., Walsh, E. I., Metcalfe, C., Lane, J. A., Martin, R. M., Tazewell, M. K., Davis, M., Peters, T. J., Turner, E. L., Mills, N., Khazragui, H., Khera, T. K., Neal, D. E., Hamdy, F. C., Bollina, P., Catto, J., Doble, A., Doherty, A., Gillatt, D. & 13 others, Gnanapragasam, V., Holding, P., Hughes, O., Kockelbergh, R., Kynaston, H., Mason, M., Oxley, J., Paul, A., Paez, E., Rosario, D. J., Rowe, E., Staffurth, J. & the ProtecT Study Group, 1 Apr 2018, In : Journal of Clinical Epidemiology. 96, p. 35-46 12 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Pragmatic Clinical Trials
  • Prostatic Neoplasms
  • Randomized Controlled Trials
  • Prostate-Specific Antigen
  • Prospective Studies
  6 Citations (Scopus)

  341 Downloads (Pure)

• Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial

  Martin, R., Donovan, J., Turner, E., Metcalfe, C., Young, G., Walsh, E., Lane, J. A., Noble, S., Oliver, S., Evans, S., Sterne, J., Holding, P. N., Ben-Shlomo, Y., Brindle, P., Williams, N., Hill, E., Ng, S. Y., Davis, J., Tazewell, M., Hughes, L. J. & 7 others, Davies, C., Thorn, J., Down, L., Davey Smith, G., Neal, D., Hamdy, F. & The CAP Trial Group, 6 Mar 2018, In : JAMA - Journal of the American Medical Association. 319, 9, p. 883-895 13 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Prostatic Neoplasms
  • Randomized Controlled Trials
  • Mortality
  • Control Groups
  • General Practice
  135 Citations (Scopus)

  528 Downloads (Pure)
• 2017

  Cross-sectional study evaluating data quality of the National Cancer Registration and Analysis Service (NCRAS) prostate cancer registry data using the Cluster randomised trial of PSA testing for Prostate cancer (CAP)

  Merriel, S. W. D., Turner, E., Walsh, E., Young, G., Metcalfe, C., Hounsome, L., Tudge, I., Donovan, J., Hamdy, F., Neal, D. & Martin, R., Nov 2017, In : BMJ Open. 7, 11, 6 p., e015994.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Data Accuracy
  • Registries
  • Prostatic Neoplasms
  • Cross-Sectional Studies
  • Neoplasms
  4 Citations (Scopus)

  198 Downloads (Pure)

• Effect of Oral Prednisolone on Symptom Duration and Severity in Nonasthmatic Adults With Acute Lower Respiratory Tract Infection: A Randomized Clinical Trial

  Hay, A. D., Little, P., Harnden, A., Thompson, M., Wang, K., Kendrick, D., Orton, E., Brookes, S. T., Young, G. J., May, M., Hollinghurst, S., Carroll, F. E., Downing, H., Timmins, D., Lafond, N., El-Gohary, M. & Moore, M., 22 Aug 2017, In : JAMA - Journal of the American Medical Association. 318, 8, p. 721-730 10 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Prednisolone
  • Respiratory Tract Infections
  • Cough
  • Randomized Controlled Trials
  • Minimal Clinically Important Difference
  20 Citations (Scopus)

  208 Downloads (Pure)

• Informed consent in randomised controlled trials: development and preliminary evaluation of a measure of Participatory and Informed Consent (PIC)

  Wade, J., Elliott, D., Avery, K., Gaunt, D., Young, G., Barnes, R., Paramasivan, S., Campbell, B., Blazeby, J., Birtle, A., Stein, R. C., Beard, D., Halliday, A. W. & Donovan, J., 17 Jul 2017, In : Trials. 18, 13 p., 327.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Informed Consent
  • Appointments and Schedules
  • Randomized Controlled Trials
  • Reproducibility of Results
  • Patient Participation
  5 Citations (Scopus)

  351 Downloads (Pure)

• Prostate Specific Antigen (PSA) testing of men in UK general practice: a 10-year longitudinal cohort study

  Young, G., Harrison, S., Turner, E., Walsh, E., Oliver, S., Ben-Shlomo, Y., Evans, S., Lane, J. A., Neal, D., Hamdy, F., Donovan, J., Martin, R. & Metcalfe, C., Oct 2017, In : BMJ Open. 7, 10, 11 p., e017729.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Prostate-Specific Antigen
  • General Practice
  • Longitudinal Studies
  • Cohort Studies
  • Prostatic Neoplasms
  13 Citations (Scopus)

  66 Downloads (Pure)

• Statistical analysis plan for the Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM)

  Young, G., Lewis, A., Lane, J. A., Winton, H., Drake, M. & Blair, P., 3 Oct 2017, In : Trials. 18, 7 p., 455.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Urodynamics
  • Prostate
  • Lower Urinary Tract Symptoms
  • Random Allocation
  • Registries
  8 Citations (Scopus)

  304 Downloads (Pure)
• 2016

  Patient-reported outcomes in the ProtecT randomised trial of clinically localised prostate cancer treatments: study design and baseline urinary, bowel and sexual function and quality of life

  Lane, A., Metcalfe, C., Young, G., Peters, TJ., Blazeby, J., Avery, K., Dedman, DJ., Down, L., Mason, MD., Neal, DE., Hamdy, FC. & Donovan, J., Dec 2016, In : BJU International. 118, 6, p. 869-879 11 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Patient Reported Outcome Measures
  • Prostatic Neoplasms
  • Quality of Life
  • Prostate-Specific Antigen
  • Anxiety
  33 Citations (Scopus)

  274 Downloads (Pure)
• 2015

  Evaluating informed consent during trial recruitment consultations: development and preliminary evaluation of a new method

  Wade, J., Townsend, D., Gaunt, D., Avery, K., Young, G. & Donovan, J., 16 Nov 2015, In : Trials. 16, Suppl 2, 1 p., P118.

  Research output: Contribution to journal › Article (Academic Journal)

• Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM) for diagnosis and management of bladder outlet obstruction in men: study protocol for a randomised controlled trial

  Bailey, K., Abrams, P. H., Blair, P. S., Chapple, C., Glazener, C. M. A., Horwood, J. P., Lane, A., McGrath, J., Noble, S. M., Pickard, R., Taylor, G., Young, G. J., Drake, M. & Lewis, A. L., 10 Dec 2015, In : Trials. 16, 21 p., 567.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Urinary Bladder Neck Obstruction
  • Urodynamics
  • Prostate
  • Randomized Controlled Trials
  • National Health Programs
  29 Citations (Scopus)

  368 Downloads (Pure)