1991 …2020

Research output per year

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Research Output

  • 63 Article (Academic Journal)
  • 2 Chapter in a book
  • 1 Conference Contribution (Conference Proceeding)
2020

Raftlin is recruited by neuropilin-1 to the activated VEGFR2 complex to control proangiogenic signaling

Bayliss, A., Sundararaman, A., Granet, C. & Mellor, H., 9 Apr 2020, In : Angiogenesis. 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
14 Downloads (Pure)
2019

Characterization of the polarized endothelial secretom

Wei, H., Sundararaman, A., Dickson, E. J., Rennie-Campbell, L., Cross, E., Heesom, K. J. & Mellor, H., 20 Aug 2019, In : FASEB Journal. 11 p.

Research output: Contribution to journalArticle (Academic Journal)

File
94 Downloads (Pure)
2018

Direct Activation of NADPH Oxidase 2 by 2-Deoxyribose-1-Phosphate Triggers Nuclear Factor Kappa B-Dependent Angiogenesis

Vara, D., Watt, J. M., Fortunato, T. M., Mellor, H., Burgess, M., Wicks, K., Mace, K., Reeksting, S., Lubben, A., Wheeler-Jones, C. P. D. & Pula, G., 10 Jan 2018, In : Antioxidants and Redox Signaling. 28, 2, p. 110-130 21 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
12 Citations (Scopus)
207 Downloads (Pure)

Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression

Gurevich, D., Severn, C., Twomey, C., Greenhough, A., Cash, J., Toye, A., Mellor, H. & Martin, P., 2 Jul 2018, In : EMBO Journal. 37, 13, 23 p., e97786.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
25 Citations (Scopus)
288 Downloads (Pure)
2017

The tumor suppressor RhoBTB1 controls Golgi integrity and breast cancer cell invasion through METTL7B

McKinnon, C. & Mellor, H., 20 Feb 2017, In : BMC Cancer. 17, 9 p., 145.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
10 Citations (Scopus)
247 Downloads (Pure)
2016

In Vitro Coculture Assays of Angiogenesis

Richards, M. D. & Mellor, H., 2016, Angiogenesis Protocols. Martin, S. G. & Hewett, P. W. (eds.). Springer, p. 159-166 8 p. (Methods in Molecular Biology; vol. 1430).

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

2015

Platelet Rho GTPases-a focus on novel players, roles and relationships

Goggs, R., Williams, C. M., Mellor, H. & Poole, A. W., 15 Mar 2015, In : Biochemical Journal. 466, 3, p. 431-42 12 p.

Research output: Contribution to journalArticle (Academic Journal)

27 Citations (Scopus)

The coculture organotypic assay of angiogenesis

Allen, J. L. & Mellor, H., 2015, In : Methods in Molecular Biology. 1214, p. 265-70 6 p.

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)

The Formin FMNL3 Controls Early Apical Specification in Endothelial Cells by Regulating the Polarized Trafficking of Podocalyxin

Richards, M. D., Hetheridge, C. L. & Mellor, H., 31 Aug 2015, In : Current Biology. 27, 17, p. 2325-2331 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
14 Citations (Scopus)
269 Downloads (Pure)

The Rif GTPase regulates cytoskeletal signaling from plexinA4 to promote neurite retraction

Fan, L., Yan, H., Pellegrin, S., Morigen, N. V. & Mellor, H., 17 Mar 2015, In : Neuroscience Letters. 590, p. 178-83 6 p.

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)
2013

RhoG regulates platelet granule secretion and thrombus formation in mice

Goggs, R., Harper, M. T., Pope, R. J., Savage, J. S., Williams, C. M., Mundell, S. J., Heesom, K. J., Bass, M., Mellor, H. & Poole, A. W., 8 Oct 2013, In : Journal of Biological Chemistry.

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)

RNA interference approaches to examine Golgi function in animal cell culture

Miller, V. J., McKinnon, C. M., Mellor, H. & Stephens, D. J., 2013, In : Methods in Cell Biology. 118, p. 15-34 20 p.

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)

The small GTPase Rif is dispensable for platelet filopodia generation in mice.

Goggs, R. A. N., Savage, J. S., Mellor, H. & Poole, A. W., 2013, In : PLoS ONE. 8, 1

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)
2012

The formin FMNL3 is a cytoskeletal regulator of angiogenesis

Hetheridge, C., Scott, A. N., Swain, R. K., Copeland, J. W., Higgs, H. N., Bicknell, R. & Mellor, H., Mar 2012, In : Journal of Cell Science. 125, 6, p. 1420-8 9 p.

Research output: Contribution to journalArticle (Academic Journal)

32 Citations (Scopus)

The small Rho GTPase Rif and actin cytoskeletal remodelling

Fan, L. & Mellor, H., Feb 2012, In : Biochemical Society Transactions. 40, 1, p. 268-72 5 p.

Research output: Contribution to journalArticle (Academic Journal)

15 Citations (Scopus)
2011

Site recognition and substrate screens for PKN family proteins

Collazos, A., Michael, N., Whelan, R. D. H., Kelly, G., Mellor, H., Pang, L. C. H., Totty, N. & Parker, P. J., 2011, In : International Journal of Biochemistry and Cell Biology. 438, 3, p. 535-43 9 p.

Research output: Contribution to journalArticle (Academic Journal)

14 Citations (Scopus)

Uses of the in vitro endothelial-fibroblast organotypic co-culture assay in angiogenesis research

Hetheridge, C., Mavria, G. & Mellor, H., 2011, In : Biochemical Society Transactions. 39, 6, p. 1597-600 4 p.

Research output: Contribution to journalArticle (Academic Journal)

33 Citations (Scopus)
2010

RhoBTB proteins in cancer

McKinnon, CM. & Mellor, H., 2010, Rho GTPases and Cancer. New York: Springer, p. 111-121

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

The role of formins in filopodia formation

Mellor, H., Feb 2010, In : Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1803, 2, p. 191-200 10 p.

Research output: Contribution to journalArticle (Academic Journal)

The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells

Fan, L., Pellegrin, S., Scott, A. & Mellor, H., Apr 2010, In : Journal of Cell Science. 123 , 8, p. 1247 - 1252 6 p.

Research output: Contribution to journalArticle (Academic Journal)

26 Citations (Scopus)
2009

VEGFR1 (Flt1) regulates Rab4 recycling to control fibronectin polymerization and endothelial vessel branching

Jones, MC., Caswell, PT., Moran-Jones, K., Roberts, M., Barry, ST., Gampel, A., Mellor, H. & Norman, JC., Jun 2009, In : Traffic. 10 (6), p. 754 - 766 13 p.

Research output: Contribution to journalArticle (Academic Journal)

32 Citations (Scopus)

VEGF receptor trafficking in angiogenesis

Scott, A. & Mellor, H., Dec 2009, In : Biochemical Society Transactions. 37, Pt 6, p. 1184-8 5 p.

Research output: Contribution to journalArticle (Academic Journal)

34 Citations (Scopus)
2008

Escherichia coli isolated from bovine mastitis invade mammary cells by a modified endocytic pathway

Passey, S., Bradley, A. & Mellor, H., Jul 2008, In : Veterinary Microbiology. 130 (1-2), p. 151 - 164 14 p.

Research output: Contribution to journalArticle (Academic Journal)

18 Citations (Scopus)

Farnesyltransferase inhibitors target multiple endothelial cell functions in angiogenesis

Scott, A. N., Hetheridge, C., Reynolds, A. R., Nayak, V., Hodivala-Dilke, K. & Mellor, H., Dec 2008, In : Angiogenesis. 11 , 4, p. 337 - 346 10 p.

Research output: Contribution to journalArticle (Academic Journal)

6 Citations (Scopus)

Rho GTPase activation assays

Pellegrin, S. & Mellor, H., 2008, In : Current Protocols in Cell Biology. Unit 14.8

Research output: Contribution to journalArticle (Academic Journal)

23 Citations (Scopus)

The atypical Rho GTPase RhoBTB2 is required for expression of the chemokine CXCL14 in normal and cancerous epithelial cells

McKinnon, C. M., Lygoe, K. A., Skelton, L., Mitter, R. & Mellor, H., Nov 2008, In : Oncogene. 27 , 54, p. 6856 - 6865 10 p.

Research output: Contribution to journalArticle (Academic Journal)

28 Citations (Scopus)
2007

Actin stress fibres

Pellegrin, S. & Mellor, H., Oct 2007, In : Journal of Cell Science. 120(20), p. 3491 - 3499 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Scanning electron microscopy of cell surface morphology

Passey, S., Pellegrin, S. & Mellor, H., Dec 2007, In : Current Protocols in Cell Biology. Chapter 4, p. Unit4.17

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

Up-Regulation of Myometrial RHO Effector Proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) Phosphorylation in Human Pregnancy Is Associated with Increased GTP-RHOA in Spontaneous Preterm Labor

Lartey, JP., Smith, MP., Pawade, J., Strachan, BK., Mellor, H. & López Bernal, A., Jun 2007, In : Biology of Reproduction. 76 (6), p. 971 - 982 12 p.

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)
2006

Expression of RND proteins in human myometrium

Lartey, J., Gampel, A., Pawade, J., Mellor, H. & Bernal, A. L., Sep 2006, In : Biology of Reproduction. 75, 3, p. 452 - 461 10 p.

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)

VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment

Gampel, A., Moss, L., Jones, M. C., Brunton, V., Norman, J. C. & Mellor, H., 15 Oct 2006, In : Blood. 108, 8, p. 2624 - 2631 8 p.

Research output: Contribution to journalArticle (Academic Journal)

130 Citations (Scopus)
2005

Lipids, Rafts and Traffic / Chapter 19 / Translocation of the cell-penetrating Tat peptide across artificial bilayers and into living cells

Curnow, P., Mellor, H., Stephens, DJ., Lorch, M. & Booth, PJ., 2005, Biochemical Society Symposium. Vol. 72. p. 199 - 209 11 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

7 Citations (Scopus)

The Rho family GTPase Rif induces filopodia through mDia2

Pellegrin, S. & Mellor, H., 26 Jan 2005, In : Current Biology. 15, 2, p. 129 - 133 5 p.

Research output: Contribution to journalArticle (Academic Journal)

195 Citations (Scopus)
2004

Cell motility: Golgi signalling shapes up to ship out

Mellor, H., 2004, In : Current Biology. 14, p. R434 - R435 2 p.

Research output: Contribution to journalArticle (Academic Journal)

31 Citations (Scopus)

Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase

Wherlock, M., Gampel, A., Futter, C. & Mellor, H., 1 Jul 2004, In : Journal of Cell Science. 117 (15), p. 3221 - 3231 11 p.

Research output: Contribution to journalArticle (Academic Journal)

90 Citations (Scopus)

RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane

Sandilands, E., Cans, C., Fincham, VJ., Brunton, VG., Mellor, H., Prendergast, GC., Norman, JC., Superti-Furga, G. & Frame, MC., 2004, In : Developmental Cell. 7, p. 855 - 869 15 p.

Research output: Contribution to journalArticle (Academic Journal)

198 Citations (Scopus)

S1P and LPA trigger schwann cell actin changes and migration

Barber, SC., Mellor, H., Gampel, A. & Scolding, NJ., Jun 2004, In : European Journal of Neuroscience. 19 (12), p. 3142 - 3150 9 p.

Research output: Contribution to journalArticle (Academic Journal)

33 Citations (Scopus)

Sorting Nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high-curvature membranes and 3-phosphoinositides

Carlton, J., Bunjy, M., Peter, BJ., Oorschot, VMJ., Rutherford, A., Mellor, H., Klumperman, J., McMahon, HT. & Cullen, PJ., Oct 2004, In : Current Biology. 14 (20), p. 1791 - 1800 10 p.

Research output: Contribution to journalArticle (Academic Journal)

311 Citations (Scopus)

What is in a filopodium? Starfish versus hedgehogs

Passey, S., Pellegrin, S. & Mellor, H., 2004, In : Biochemical Society Transactions. 32, p. 1115 - 1117 3 p.

Research output: Contribution to journalArticle (Academic Journal)

23 Citations (Scopus)
2003

Regulation of endocytic traffic by Rho GTPases

Qualmann, B. & Mellor, H., 2003, In : Biochemical Journal. 371, p. 233 - 241

Research output: Contribution to journalArticle (Academic Journal)

99 Citations (Scopus)

Synergistic roles for the Map and Tir effector molecules in mediating uptake of enteropathogenic Escherichia coli (EPEC) into non-phagocytic cells

Jepson, MA., Pellegrin, S., Peto, L., Banbury, DN., Leard, AD., Mellor, H. & Kenny, B., Nov 2003, In : Cellular Microbiology. 5 (11), p. 773 - 783 11 p.

Research output: Contribution to journalArticle (Academic Journal)

55 Citations (Scopus)
2002

Co-ordinate regulation of distinct host cell signalling pathway by multifunctional enteropathogenic Escherichia coli effector molecules

Kenny, B., Ellis, S., Leard, AD., Warawa, J., Mellor, H. & Jepson, MA., May 2002, In : Molecular Microbiology. 44 (4), p. 1095 - 1107 13 p.

Research output: Contribution to journalArticle (Academic Journal)

131 Citations (Scopus)

Functional coupling of rat metabotropic glutamate 1a receptors to phospholipase D in CHO cells: involvement of extracellular Ca2+, protein kinase C, tyrosine kinase and Rho-A

Kanumilli, S., Toms, NJ., Venkateswarlu, K., Mellor, H. & Roberts, PJ., Jan 2002, In : Neuropharmacology. 42 (1), p. 1 - 8 8 p.

Research output: Contribution to journalArticle (Academic Journal)

16 Citations (Scopus)

Identification and characterization of a novel activated RhoB binding protein containing a PDZ domain whose expression is specifically modulated in thyroid cells by cAMP

Mircescu, H., Steuve, S., Savonet, V., Degraef, C., Mellor, H., Dumont, JE., Maenhaut, C. & Pirson, I., 2002, In : European Journal of Biochemistry. 269, p. 6241 - 6249

Research output: Contribution to journalArticle (Academic Journal)

14 Citations (Scopus)

Small interfering RNAs as a tool to assign Rho GTPase exchange-factor function in vivo

Gampel, A. & Mellor, H., Sep 2002, In : Biochemical Journal. 366 (2), p. 393 - 398 6 p.

Research output: Contribution to journalArticle (Academic Journal)

38 Citations (Scopus)
126 Citations (Scopus)

The Rho GTPase family: a Racs to Wrchs story

Wherlock, MD. & Mellor, H., 2002, In : Journal of Cell Science. 115, p. 239 - 240

Research output: Contribution to journalArticle (Academic Journal)

98 Citations (Scopus)
2001

Cell cycle-dependent phosphorylation of the translational repressor eIF-4E binding protein-1 (4E-BP1)

Heesom, KJ., Gampel, A., Mellor, H. & Denton, RM., 4 Sep 2001, In : Current Biology. 11, 17, p. 1374-1379 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Cell cycle-dependent phosphorylation of the translational repressor elF-4E binding protein-1 (4E-BP1)

Heesom, KJ., Gampel, A., Mellor, H. & Denton, RM., 4 Sep 2001, In : Current Biology. 11 (17), p. 1374 - 1379 6 p.

Research output: Contribution to journalArticle (Academic Journal)

111 Citations (Scopus)

Modular phosphoinositide-binding domains - their role in signalling and membrane trafficking

Cullen, PJ., Cozier, GE., Banting, GS. & Mellor, H., 2001, In : Current Biology. 11(R), p. 882 - 893

Research output: Contribution to journalArticle (Academic Journal)

145 Citations (Scopus)