Helena J M Smartt

2024

Efficacy of propofol-supplemented cardioplegia on biomarkers of organ injury in patients having cardiac surgery using cardiopulmonary bypass: a statistical analysis plan for the ProMPT-2 randomised controlled trial

Smartt, H., Angelini, G. D., Gibbison, B. & Rogers, C. A., 29 Feb 2024, In: Trials. 25, 1, 153.

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Open Access

2023

Efficacy of propofol-supplemented cardioplegia on biomarkers of organ injury in patients having cardiac surgery using cardiopulmonary bypass: A protocol for a randomised controlled study (ProMPT2)

Heys, R., Angelini, G. D., Joyce, K., Smartt, H., Culliford, L., Maishman, R., de Jesus, S. E., Emanueli, C., Suleiman, M.-S., Punjabi, P., Rogers, C. A. & Gibbison, B., 16 Feb 2023, (E-pub ahead of print) In: Perfusion.

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Open Access

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1 Citation (Scopus)

76 Downloads (Pure)

Warm versus cold blood cardioplegia in paediatric congenital heart surgery: a randomized trial

Stoica, S. C., Smartt, H. J. M., Heys, R. L., Sheehan, K., Walker-Smith, T. A. F., Parry, A., Beringer, R. M., Ttofi, I., Evans, R. N., Dabner, L. S., Ghorbel, M., Lansdowne, W., Reeves, B. C., Angelini, G. D., Rogers, C. A. & Caputo, M., 1 Apr 2023, In: European Journal of Cardio-Thoracic Surgery. 63, 4, 10 p., ezad041.

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Open Access

2022

Outcome Monitoring After Cardiac Surgery (OMACS): a single-centre prospective cohort study of cardiac surgery patients

Walker-Smith, T. A. F., Joyce, K. P., Maishman, R. L., Smartt, H. J. M., Hopkins, E. J., Brierley, R. C. M., Reeves, B. C., Rogers, C. A., Angelini, G. D. & Culliford, L. A., 19 Dec 2022, In: BMJ Open. 12, 12, 6 p., e063268.

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1 Citation (Scopus)

43 Downloads (Pure)

The effects of multimedia information on recruitment and retention in a children’s cardiac surgery trial: a randomised controlled SWAT (study within a trial) [version 1; peer review: awaiting peer review]

Knapp, P., Heys, R., Dabner, L., Sheehan, K., Smartt, H., Walker-Smith, T., Rogers, C. A., Stoica, S., Roche, J., Moe-Byrne, T., Martin-Kerry, J. M., Sheridan, R., Coleman, E., Higgins, S. & Steven, H., 21 Mar 2022, In: F1000Research.

Research output: Contribution to journal › Article (Academic Journal)

Open Access

2 Citations (Scopus)

2021

Cost-effectiveness of the i-gel supraglottic airway device compared to tracheal intubation during out-of-hospital cardiac arrest: Findings from the AIRWAYS-2 randomised controlled trial

A. Stoke, E., Lazaroo, M. J., Clout, M. J., Rogers, C. A., J. brett, S., Black, S., UK, S. W. A. S. N. F. T., Nolan, J. P., Reeves, B. C., Robinson, M., Scott, L. J., Smartt, H. J. M., Taylor, J., Thomas, M. A., Voss, S., UK, U. O. T. W. O. E. G. C. & UK, O. N. B. R. C., Oct 2021, In: Resuscitation. 167, p. 1-9 9 p.

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5 Citations (Scopus)

186 Downloads (Pure)

2020

Impact of rapid microbial identification on clinical outcomes in bloodstream infection: the RAPIDO randomized trial.

Macgowan, A. P., Grier, S., Stoddart, M., Reynolds, R. A., Rogers, C. A., Pike, K. E., Smartt, H. J. M., Wilcox, M., Wilson, P., Kelsey, M., Steer, J., Gould, F. K., Perry, J. D., Howe, R. & Wootton, M., 24 Jan 2020, (Accepted/In press) In: Clinical Microbiology and Infection.

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16 Citations (Scopus)

Randomized Trial of the i-gel Supraglottic Airway Device Versus Tracheal Intubation During Out of Hospital Cardiac Arrest (AIRWAYS-2): Patient Outcomes at Three and Six Months

Benger, J. R., Lazaroo, M. J., Clout, M. J., Voss, S., Black, S., J. brett, S., Kirby, K., Nolan, J. P., Reeves, B. C., Robinson , M., Scott, L. J., Smartt, H. J. M., South, A., Taylor, J., Thomas, M. A., Wordsworth, S. & Rogers, C. A., 1 Dec 2020, In: Resuscitation. 157, p. P74-82 9 p.

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10 Citations (Scopus)

85 Downloads (Pure)

2018

Effect of a strategy of supraglottic airway device versus tracheal intubation during out-of-hospital cardiac arrest on functional outcome: the AIRWAYS-2 randomized clinical trial

Benger, J., Kirby, K., Black, S., Brett, S., Clout, M., Lazaroo, M., Nolan, J., Reeves, B., Robinson, M., Scott, L., Smartt, H., South, A., Stokes, E. A., Taylor, J., Thomas, M., Voss, S., Wordsworth , S. & Rogers, C., 28 Aug 2018, In: JAMA - Journal of the American Medical Association. 320, 8, p. 779-791 13 p.

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288 Citations (Scopus)

358 Downloads (Pure)

2017

Home-based Reach-to-Grasp training for people after stroke is feasible: A pilot randomised controlled trial

Turton, A. J., Cunningham, P., Van Wijck, F., Smartt, H. J. M., Rogers, C. A., Sackley, C. M., Jowett, S., Wolf, S. L., Wheatley, K. & Van Vliet, P., Jul 2017, In: Clinical Rehabilitation. 31, 7, p. 891-903 13 p.

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15 Citations (Scopus)

291 Downloads (Pure)

2013

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk

Petherick, K. J., Williams, A. C., Lane, J. D., Ordóñez-Morán, P., Huelsken, J., Collard, T. J., Smartt, H. J., Batson, J., Malik, K., Paraskeva, C. & Greenhough, A., 4 Jun 2013, In: EMBO Journal. 32, 13, p. 1903 - 1916 14 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

253 Citations (Scopus)

LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: implications for targeting adenoma stem cells with NSAIDs

Al-Kharusi, M. R. A., Smartt, H. J. M., Greenhough, A., Collard, T. J., Emery, E. D., Williams, A. C. & Paraskeva, C., 2013, In: Carcinogenesis.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

60 Citations (Scopus)

2012

BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis

Southern, S. L., Collard, T. J., Urban, B. C., Skeen, V. R., Smartt, H. J., Hague, A., Oakley, F., Townsend, P. A., Perkins, N. D., Paraskeva, C. & Williams, A. C., 2012, In: Oncogene. 31, 22, p. 2761-2772 12 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

26 Citations (Scopus)

β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: a role in the chemopreventive efficacy of aspirin?

Smartt, H. J. M., Greenhough, A., Ordóñez-Morán , P., Al Kharusi, M. R. A., Collard, T. J., Mariadason, J., Huelsken, J., Williams, A. C. & Paraskeva, C., 23 Oct 2012, In: British Journal of Cancer. 107, 9, p. 1514-1517

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10 Citations (Scopus)

2011

B-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells

Smartt, H., Greenhough, A., Ordonez-Moran, P., Talero, E., Wallam, C., Parry, L., Al-Kharusi, M., Roberts, H., Mariadason, J., Clarke, A., Huelsken, J., Williams, A. & Paraskeva, C., Sept 2011, In: Gut. 61, 9, p. 1306-1314

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47 Citations (Scopus)

Colon tumour cells increase PGE2 by regulating COX-2 and 15-PGDH to promote survival during the microenvironmental stress of glucose deprivation

Roberts, H., Smartt, H., Greenhough, A., Moore, A., Williams, A. & Paraskeva, C., 2011, In: Carcinogenesis. In Press

Research output: Contribution to journal › Article (Academic Journal) › peer-review

2009

The COX-2/PGE2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

Greenhough, A., Smartt, H., Moore, A., Roberts, H., Williams, A., Paraskeva, C. & Kaidi, A., Jan 2009, In: Carcinogenesis. 30, p. 377 - 386 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

1069 Citations (Scopus)

2007

Insulin-like growth factor binding protein (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-κB

Williams, A., Smartt, H., H-Zadeh, A., MacFarlane, M., Paraskeva, C. & Collard, T., Jan 2007, In: Cell Death and Differentiation. 14 (1), p. 137 - 145 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

59 Citations (Scopus)

2005

Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis

Hague, A., Hicks, D., Hasan, F., Smartt, H., Cohen, G., Paraskeva, C. & MacFarlane, M., Feb 2005, In: British Journal of Cancer. 92 (4), p. 736 - 742 7 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

39 Citations (Scopus)

Dr Helena J M Smartt

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