20012020

Research output per year

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Research Output

2020

A Bayesian predictive approach for dealing with pseudoreplication

Lazic, S. E., Mellor, J. R., Ashby, M. C. & Munafo, M. R., 11 Feb 2020, In : Scientific Reports. 10, 10 p., 2366 (2020).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
48 Downloads (Pure)
Open Access
File
52 Downloads (Pure)

Interneuron-specific plasticity at parvalbumin and somatostatin inhibitory synapses onto CA1 pyramidal neurons shapes hippocampal output

Udakis, M., Pedrosa, V., Chamberlain, S. E. L., Clopath, C. & Mellor, J. R., 31 Jul 2020, (Accepted/In press) In : Nature Communications.

Research output: Contribution to journalArticle (Academic Journal)

2019

Neuromodulation of hippocampal long-term synaptic plasticity

Palacios-Filardo, J. & Mellor, J., Feb 2019, In : Current Opinion in Neurobiology. 54, p. 37-43 7 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
17 Citations (Scopus)
269 Downloads (Pure)
2018

Convergent Metabotropic Signaling Pathways Inhibit SK Channels to Promote Synaptic Plasticity in the Hippocampus

Tigaret, C. M., Chamberlain, S. E. L., Sadowski, J. H. L., Hall, J., Ashby, M. & Mellor, J., 24 Oct 2018, In : Journal of Neuroscience. 38, 43, p. 9252-9262 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
174 Downloads (Pure)

Cortactin regulates endo-lysosomal sorting of AMPARs via direct interaction with GluA2 subunit

Parkinson, G. T., Chamberlain, S. E. L., Jaafari, N., Turvey, M. R., Mellor, J. & Hanley, J., 7 Mar 2018, In : Scientific Reports. 8, 1, 17 p., 4155.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
7 Citations (Scopus)
257 Downloads (Pure)
2017

Acetylcholine modulates gamma frequency oscillations in the hippocampus by activation of muscarinic M1 receptors

Betterton, R. T., Broad, L. M., Tsaneva-Atanasova, K. & Mellor, J. R., 18 Jun 2017, In : European Journal of Neuroscience.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
8 Citations (Scopus)
321 Downloads (Pure)

Coordinated acetylcholine release in prefrontal cortex and hippocampus is associated with arousal and reward on distinct timescales

Teles Grilo Ruivo, L. M., Baker, K., Conway, M., Kinsley, P., Gilmour, G., Phillips, K., Isaac, J. T. R., Lowry, J. & Mellor, J., 24 Jan 2017, In : Cell Reports. 18, 4, p. 905–917 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
40 Citations (Scopus)
291 Downloads (Pure)
2016

Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus

Dennis, S., Pasqui, F., Colvin, E. M., Sanger, H., Mogg, A. J., Felder, C. C., Broad, L. M., Fitzjohn, S., Isaac, J. T. R. & Mellor, J., Jan 2016, In : Cerebral Cortex. 26, 1, p. 414-426 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
66 Citations (Scopus)
342 Downloads (Pure)

Assessment of Methods for the Intracellular Blockade of GABAA Receptors

Atherton, L., Burnell, E. & Mellor, J., 8 Aug 2016, In : PLoS ONE. 11, 8, 22 p., e0160900.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
267 Downloads (Pure)

Control of Ca2+ influx and calmodulin activation by SK-channels in dendritic spines

Griffith, T. J. O., Tsaneva-Atanasova, K. & Mellor, J., 27 May 2016, In : PLoS Computational Biology. 12, 5, 19 p., e1004949.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
14 Citations (Scopus)
255 Downloads (Pure)

Coordinated activation of distinct Ca2+ sources and metabotropic glutamate receptors encodes Hebbian synaptic plasticity

Tigaret, C. M., Olivo, V., Sadowski, J. H. L., Ashby, M. C. & Mellor, J. R., 13 Jan 2016, In : Nature Communications. 7, 14 p., 10289.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
31 Citations (Scopus)
269 Downloads (Pure)

Neuromodulation of the feedforward dentate gyrus-CA3 microcircuit

Prince, L., Bacon, T. J., Tigaret, C. & Mellor, J., 17 Oct 2016, In : Frontiers in Synaptic Neuroscience. 8, 16 p., 32.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
11 Citations (Scopus)
314 Downloads (Pure)

Sharp-wave ripples orchestrate the induction of synaptic plasticity during reactivation of place cell firing patterns in the hippocampus

Sadowski, J. H. L., Jones, M. & Mellor, J. R., 1 Mar 2016, In : Cell Reports. 14, 8, p. 1916-1929 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
51 Citations (Scopus)
511 Downloads (Pure)
2015

A spatiotemporal model of spine calcium dynamics in the hippocampus

Griffith, T., Tsaneva-Atanasova, K. & Mellor, J., 18 Jul 2015.

Research output: Contribution to conferenceConference Poster

Clathrin-independent trafficking of AMPA receptors

Glebov, O. O., Tigaret, C. M., Mellor, J. R. & Henley, J. M., 25 Mar 2015, In : Journal of Neuroscience. 35, 12, p. 4830-6 7 p.

Research output: Contribution to journalArticle (Academic Journal)

31 Citations (Scopus)

Memory trace replay: The shaping of memory consolidation by neuromodulation

Atherton, L. A., Duprett, D. & Mellor, J. R., 1 Sep 2015, In : Trends in Neurosciences. 38, 9, p. 560-570 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
66 Citations (Scopus)
395 Downloads (Pure)

Spike-Timing Dependent Plasticity (STDP), Biophysical Models

Griffith, T., Tsaneva-Atanasova, K. & Mellor, J., 24 Mar 2015, Encyclopedia of Computational Neuroscience.

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

2013

Cholinergic modulation of hippocampal network function

Teles-Grilo Ruivo, L. M. & Mellor, J. R., 2013, Frontiers in Synaptic Neuroscience, 5, 2.

Research output: Contribution to specialist publicationArticle (Specialist Publication)

92 Citations (Scopus)

Homeostatic synaptic scaling is regulated by protein SUMOylation (vol 287, pg 22781, 2012)

Craig, T. J., Jaafari, N., Petrovic, M. M., Jacobs, S. C., Rubin, P. P., Mellor, J. R. & Henley, J. M., 8 Feb 2013, In : Journal of Biological Chemistry. 288, 6, p. 4208-4208 1 p.

Research output: Contribution to journalArticle (Academic Journal)

Long-Term Depression of Synaptic Kainate Receptors Reduces Excitability by Relieving Inhibition of the Slow Afterhyperpolarization

Chamberlain, S. E. L., Sadowski, J. H. L., Teles-Grilo Ruivo, L. M., Atherton, L. A. & Mellor, J. R., 29 May 2013, In : Journal of Neuroscience. 33, 22, p. 9536-9545 10 p.

Research output: Contribution to journalArticle (Academic Journal)

14 Citations (Scopus)

The Small GTPase Arf1 Modulates Arp2/3-Mediated Actin Polymerization via PICK1 to Regulate Synaptic Plasticity

Rocca, D. L., Amici, M., Antoniou, A., Blanco Suarez, E., Halemani, N., Murk, K., McGarvey, J., Jaafari, N., Mellor, J. R., Collingridge, G. L. & Hanley, J. G., 24 Jul 2013, In : Neuron. 79, 2, p. 293-307 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
57 Citations (Scopus)
726 Downloads (Pure)

Wavelet Transform-Based De-Noising for Two-Photon Imaging of Synaptic Ca2+ Transients

Tigaret, C. M., Tsaneva-Atanasova, K. T., Collingridge, G. L. & Mellor, J. R., 2013, In : Biophysical Journal. 104, p. 1006-1017

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)
2012

Inhibition of post-synaptic Kv7/KCNQ/M channels facilitates long-term potentiation in the hippocampus

Petrovic, M. M., Nowacki, J., Olivo, V., Tsaneva-Atanasova, K., Randall, A. D. & Mellor, J. R., Feb 2012, In : PLoS ONE. 7, 2, p. 1 - 10 10 p.

Research output: Contribution to journalArticle (Academic Journal)

19 Citations (Scopus)

SUMOylation and phosphorylation of GluK2 regulate kainate receptor trafficking and synaptic plasticity

Chamberlain, S. E. L., Gonzalez, M. I., Wilkinson, K. A., Konopacki, F. A., Kantamneni, S., Henley, J. M. & Mellor, J. R., Jun 2012, In : Nature Neuroscience. 15, 6, p. 845-852 8 p.

Research output: Contribution to journalArticle (Academic Journal)

64 Citations (Scopus)
2011

Agonist-induced PKC phosphorylation regulates GluK2 SUMOylation and kainate receptor endocytosis

Konopacki, F. A., Jaafari, N., Rocca, D., Wilkinson, K. A., Chamberlain, S. E. L., Rubin, P., Kantamneni, S., Mellor, J. R. & Henley, JM., Dec 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 49, p. 19772 - 19777 6 p.

Research output: Contribution to journalArticle (Academic Journal)

48 Citations (Scopus)

Oxygen/glucose deprivation induces a reduction in synaptic AMPA receptors on hippocampal CA3 neurons mediated by mGluR1 and A3 receptors

Dennis, SH., Jaafari, N., Cimarosti, H., Hanley, JG., Henley, JM. & Mellor, JR., 17 Aug 2011, In : Journal of Neuroscience. 31, 33, p. 11941 - 11952 12 p.

Research output: Contribution to journalArticle (Academic Journal)

39 Citations (Scopus)

PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity

Nakamura, Y., Wood, C. L., Patton, A. P., Jaafari, N., Henley, J. M., Mellor, J. R. & Hanley, J. G., Feb 2011, In : EMBO Journal. 30 , 4, p. 719 - 730 12 p.

Research output: Contribution to journalArticle (Academic Journal)

71 Citations (Scopus)

Ripples Make Waves: Binding Structured Activity and Plasticity in Hippocampal Networks

Sadowski, JHL., Jones, MW. & Mellor, JR., 2011, In : Neural Plasiticity. 2011, p. 1 - 11 11 p.

Research output: Contribution to journalArticle (Academic Journal)

25 Citations (Scopus)
2010

A Ca2+-based Computational Model for NMDA Receptor-Dependent Synaptic Plasticity at Individual Postsynaptic Spines in the Hippocampus

Rackham, OJL., Tsaneva-Atanasova, KT., Ganesh, AJ. & Mellor, JR., Jul 2010, In : Frontiers in Synaptic Neuroscience. 2, p. 1 - 12 12 p.

Research output: Contribution to journalArticle (Academic Journal)

A Ca 2+-based computational model for NMDA receptordependent synaptic plasticity at individual post-synaptic spines in the hippocampus

Rackham, O. J. L., Tsaneva-Atanasova, K., Ganesh, A. & Mellor, J. R., 1 Dec 2010, In : Frontiers in Synaptic Neuroscience. JUL, Article 31.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

Dentate Gyrus Granule Cell Firing Patterns Can Induce Mossy Fiber Long-Term Potentiation In Vitro

Mistry, R., Dennis, S., Frerking, M. & Mellor, JR., 2010, In : Hippocampus. 21, p. 1157 - 1168 12 p.

Research output: Contribution to journalArticle (Academic Journal)

22 Citations (Scopus)

Facilitation of Long-Term Potentiation by Muscarinic M1 Receptors is mediated by inhibition of SK channels

Buchanan, KA., Petrovic, M., Chamberlain, SEL., Marrion, NV. & Mellor, JR., 9 Dec 2010, In : Neuron. 68, 5, p. 948 - 963 16 p.

Research output: Contribution to journalArticle (Academic Journal)

122 Citations (Scopus)

The activity requirements for spike timing-dependent plasticity in the hippocampus

Bucanan, KA. & Mellor, JR., 2010, In : Frontiers in Synaptic Neuroscience. 2, p. 1 - 5 5 p.

Research output: Contribution to journalArticle (Academic Journal)

38 Citations (Scopus)
2009

Hippocampal place cell firing patterns can induce long-term synaptic plasticity in vitro

Isaac, JTR., Buchanan, KA., Muller, RL. & Mellor, JR., 27 May 2009, In : Journal of Neuroscience. 29, 21, p. 6840 - 6850 11 p.

Research output: Contribution to journalArticle (Academic Journal)

64 Citations (Scopus)

PICK1-mediated glutamate receptor subunit 2 (GluR2) trafficking contributes to cell death in oxygen/glucose deprived hippocampal neurons

Dixon, R. M., Mellor, J. R. & Hanley, J. G., May 2009, In : Journal of Biological Chemistry. 284, 21, p. 14230 - 14235 6 p.

Research output: Contribution to journalArticle (Academic Journal)

47 Citations (Scopus)
2008

Bidirectional activity-dependent plasticity of membrane potential and the influence on spiking in rat hippocampal dentate granule cells

Mistry, RB. & Mellor, JR., Feb 2008, In : Neuropharmacology. 54(2), p. 290 - 299 10 p.

Research output: Contribution to journalArticle (Academic Journal)

2007

SUMOylation regulates kainate-receptor-mediated synaptic transmission

Martin, SAR., Nishimune, A., Mellor, JR. & Henley, JM., May 2007, In : Nature. 447 (7142), p. 321 - 325 5 p.

Research output: Contribution to journalArticle (Academic Journal)

197 Citations (Scopus)

The development of synaptic plasticity induction rules and the requirement for postsynaptic spikes in rat hippocampal CA1 pyramidal neurones

Buchanan, KA. & Mellor, JR., Dec 2007, In : Journal of Physiology. 585(Pt 2), p. 429 - 445 12 p.

Research output: Contribution to journalArticle (Academic Journal)

37 Citations (Scopus)
2006

Synaptic plasticity of kainate receptors

Mellor, JR., Nov 2006, In : Biochemical Society Transactions. 34(5), p. 949 - 951 3 p.

Research output: Contribution to journalArticle (Academic Journal)

11 Citations (Scopus)
2004

Kainate Receptor Trafficking: Physiological Roles and Molecular Mechanisms

Isaac, JTR., Mellor, JR., Hurtado, D. & Roche, KW., 2004, In : Pharmacology and Therapeutics. 104, p. 163 - 172

Research output: Contribution to journalArticle (Academic Journal)

40 Citations (Scopus)
2001

Synaptically released neurotransmitter fails to desensitize postsynaptic GABAA receptors in cerebellar cultures

Mellor, JR. & Randall, AD., May 2001, In : Journal of Neurophysiology. 85 (5), p. 1847 - 1857 11 p.

Research output: Contribution to journalArticle (Academic Journal)