19972020

Research output per year

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Personal profile

Research interests

Molecular, imaging and sophisticated viral delivery techniques are used to investigate the coding and non-coding genes that regulate neuronal function. This work includes: (i) identifying the changes in gene expression that occur in neuronal cells exposed to stress or disease causing agent; (ii) developing viral vector systems optimized to study neuronal function; (iii) developing stem cell and induced pluripotent stem cell models of human disease conditions; (iv) how miRNAs and RNA binding proteins influence the expression of genes involved in the control of fundamental neuronal processes.

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Projects

Research Output

  • 85 Article (Academic Journal)
  • 4 Conference Contribution (Conference Proceeding)
  • 1 Conference Paper
  • 1 Conference Poster
  • Open Access
    File
  • 39 Downloads (Pure)

    Dual druggable genome siRNA and compound screening approaches identify novel modulators of parkin recruitment to mitochondria

    Scott, H. L., Buckner, N., Fernandez-Albert, F., Pedone, E., Postiglione, L., Shi, G., Allen, N., Wong, L-F., Magini, L., Marucci, L., O’Sullivan, G., Cole, S., Powell, J., Maycox, P. & Uney, J. B., 7 Jan 2020, In : Journal of Biological Chemistry.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 59 Downloads (Pure)

    Supervised Work

    A Viral Approach to Translatome Profiling of CA1 Neurons During Associative Recognition Memory Formation

    Author: Gaunt, J., 25 Sep 2018

    Supervisor: Uney, J. (Supervisor), Warburton, C. (Supervisor) & Marucci, L. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    Examining the Role of Placental-derived MicroRNA Secretions in Response to Gestational Hypoxia on Foetal Neurodevelopment

    Author: Bignell, A. L., 23 Jan 2020

    Supervisor: Case, C. P. (Supervisor), Perks, C. M. (Supervisor), Uney, J. B. (Supervisor) & Fulga, T. A. (External person) (Supervisor)

    Student thesis: Master's ThesisMaster of Science (MSc)

    File

    Investigating synucleinopathies using translating ribosome affinity purification in cellular Parkinson’s disease models

    Author: Khazim, M., 7 May 2019

    Supervisor: Uney, J. (Supervisor) & Wong, L. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File