Research output per year
Research output per year
Research output
- 1 - 50 out of 87 results
Search results
-
2023
AZD5438 a GSK-3a/b and CDK inhibitor is antiapoptotic modulates mitochondrial activity and protects human neurons from mitochondrial toxins
Shi, G., Scott, H., Azhar, N. I. F. M., Gialeli, A., Clennell, B., Lee, K. S., Hurcombe, J., Whitcomb, D., Coward, R., Wong, L.-F., Cordero-Llana, O. & Uney, J. B., 23 May 2023, In: Scientific Reports. 13, 1, 13 p., 8334 (2023).Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access5 Citations (Scopus) -
The miRNA transcriptome of cerebrospinal fluid in preterm infants reveals the signaling pathways that promote reactive gliosis following cerebral hemorrhage
Gialeli, A., Spaull, R., Plösch, T., Uney, J. B., Cordero Llana, O. & Heep, A., 18 Sept 2023, In: Frontiers in Molecular Neuroscience. 16, 1211373.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access2 Citations (Scopus) -
2020
Abnormal scaffold attachment factor 1 expression and localisation in spinocerebellar ataxias and huntington’s chorea
Buckner, N., Kemp, K. C., Scott, H. L., Shi, G., Rivers, C. A., Gialeli, A., Wong, L.-F., Cordero Llana, O., Allen, N., Wilkins, A. & Uney, J. B., 1 Nov 2020, In: Brain Pathology. 15 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile4 Citations (Scopus)140 Downloads (Pure) -
A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria
Scott, H. L., Buckner, N., Fernandez-Albert, F., Pedone, E., Postiglione, L., Shi, G., Allen, N., Wong, L.-F., Magini, L., Marucci, L., O’Sullivan, G., Cole, S., Powell, J., Maycox, P. & Uney, J. B., 6 Mar 2020, In: Journal of Biological Chemistry. 295, p. 3285-3300 16 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile10 Citations (Scopus)283 Downloads (Pure) -
CREB transcription in the medial prefrontal cortex regulates the formation of long-term associative recognition memory
Barker, G. R., Wong, L. F., Uney, J. B. & Warburton, E. C., 1 Feb 2020, In: Learning and Memory. 27, 2, p. 45-51 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile8 Citations (Scopus)328 Downloads (Pure) -
2019
Exosomes populate the cerebrospinal fluid of preterm infants with post-haemorrhagic hydrocephalus
Spaull, R., McPherson, B., Gialeli, A., Clayton, A., Uney, J., Heep, A. & Cordero-Llana, Ó., Apr 2019, In: International Journal of Developmental Neuroscience. 73, p. 59-65 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile37 Citations (Scopus)174 Downloads (Pure) -
Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function
Hurcombe, J. A., Hartley, P., Lay, A. C., Ni, L., Bedford, J. J., Leader, J. P., Singh, S., Murphy, A., Scudamore, C. L., Marquez, E., Barrington, A. F., Pinto, V., Marchetti, M., Wong, L.-F., Uney, J., Saleem, M. A., Mathieson, P. W., Patel, S., Walker, R. J. & Woodgett, J. R. & 3 others, , 24 Jan 2019, (E-pub ahead of print) In: Nature Communications. 10, 1, 17 p., 403.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile57 Citations (Scopus)610 Downloads (Pure) -
shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth
Haynes, H. R., Scott, H. L., Killick-Cole, C. L., Shaw, G., Brend, T., Hares, K. M., Redondo, J., Kemp, K. C., Ballesteros, L. S., Herman, A., Cordero-Llana, O., Singleton, W. G., Mills, F., Batstone, T., Bulstrode, H., Kauppinen, R. A., Wurdak, H., Uney, J. B., Short, S. C. & Wilkins, A. & 1 others, , 1 Apr 2019, In: Journal of Pathology. 247, 4, p. 422-434 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile18 Citations (Scopus)447 Downloads (Pure) -
2017
Contrasting roles for DNA methyltransferases and histone deacetylases in single-item and associative recognition memory
Scott, H., Smith, A. E., Barker, G. R., Uney, J. B. & Warburton, E. C., 6 Mar 2017, In: Neuroepigenetics. 9, 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile12 Citations (Scopus)465 Downloads (Pure) -
Loss of MicroRNA-7 Regulation Leads to α-Synuclein Accumulation and Dopaminergic Neuronal Loss In Vivo
McMillan, K. J., Murray, T. K., Bengoa-Vergniory, N., Cordero-Llana, O., Cooper, J., Buckley, A., Wade-Martins, R., Uney, J. B., O'Neill, M. J., Wong, L. F. & Caldwell, M. A., 4 Oct 2017, In: Molecular Therapy. 25, 10, p. 2404-2414 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile122 Citations (Scopus)379 Downloads (Pure) -
Recognition memory-induced gene expression in the perirhinal cortex: A transcriptomic analysis
Scott, H., Rogers, M. F., Scott, H. L., Campbell, C., Warburton, E. C. & Uney, J. B., 15 Jun 2017, In: Behavioural Brain Research. 328, p. 1-12 12 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile7 Citations (Scopus)559 Downloads (Pure) -
Separate elements of episodic memory subserved by distinct hippocampal-prefrontal connections
Barker, G., Banks, P., Scott, H., Wong, L.-F., Bashir, Z., Uney, J., Warburton, C., Banks, P. J. & Scott Ralph, G., Feb 2017, In: Nature Neuroscience. 20, 2, p. 242–250 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile86 Citations (Scopus)805 Downloads (Pure) -
Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury
Carwardine, D., Prager, J., Neeves, J., Muir, E. M., Uney, J., Granger, N. & Wong, L.-F., 11 Dec 2017, In: PLoS ONE. 12, 12, p. e0188967Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile20 Citations (Scopus)307 Downloads (Pure) -
2016
MiR-132 Is Upregulated by Ischemic Preconditioning of Cultured Hippocampal Neurons and Protects them from Subsequent OGD Toxicity
Keasey, M. P., Scott, H. L., Bantounas, I., Uney, J. B. & Kelly, S., Jul 2016, In: Journal of Molecular Neuroscience. 59, 3, p. 404-410 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
20 Citations (Scopus) -
The increasing diversity of functions attributed to the SAFB family of RNA/DNA binding proteins
Norman, M., Rivers, C., Lee, Y. B., Idris, J. & Uney, J., Dec 2016, In: Biochemical Journal. 473, 23, p. 4271-4288 18 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile34 Citations (Scopus)560 Downloads (Pure) -
2015
Enhanced efficacy of the CDNF/MANF family by combined intranigral overexpression in the 6-OHDA rat model of Parkinson's disease
Cordero-Llana, Ó., Houghton, B. C., Rinaldi, F., Taylor, H., Yáñez-Muñoz, R. J., Uney, J. B., Wong, L.-F. & Caldwell, M. A., 1 Feb 2015, In: Molecular Therapy. 23, 2, p. 244-54 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
73 Citations (Scopus) -
iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function
Rivers, C. A., Idris, J., Scott, H. L., Rogers, M. F., Lee, Y.-B., Gaunt, J. R., Phylactou, L., Curk, T., Campbell, I. C. G., Ule, J., Norman, M. R. & Uney, J. B., 22 Dec 2015, In: BMC Biology. 13, 1, 15 p., 111.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile20 Citations (Scopus)425 Downloads (Pure) -
2014
Cross-regulation of Connexin43 and β-catenin influences differentiation of human neural progenitor cells.
Rinaldi, F., Hartfield, E., Crompton, L. A., Badger, J., Glover, C., Kelly, C., Rosser, A., Uney, J. B. & Caldwell, M. A., 23 Jan 2014, In: Cell Death and Disease.Research output: Contribution to journal › Article (Academic Journal) › peer-review
43 Citations (Scopus) -
miR-186 inhibits muscle cell differentiation through myogenin regulation
Antoniou, A., Mastroyiannopoulos, N. P., Uney, J. B. & Phylactou, L. A., 14 Feb 2014, In: Journal of Biological Chemistry. 289, 7, p. 3923-35 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
65 Citations (Scopus) -
2013
Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A
Szemes, M., Dallosso, A. R., Melegh, Z. B., Curry, T. J., Li, Y., Rivers, C. A., Uney, J. B., Magdefrau, A.-S., Schwiderski, K., Park, J., Brown, K. W., Shandilya, J., Roberts, S. G. E. & Malik, K. T. A., 1 Jan 2013, In: Human Molecular Genetics. 22, 1, p. 74-83Research output: Contribution to journal › Article (Academic Journal) › peer-review
32 Citations (Scopus) -
Twist reverses muscle cell differentiation through transcriptional down-regulation of myogenin
Mastroyiannopoulos, N. P., Antoniou, A. A., Koutsoulidou, A., Uney, J. B. & Phylactou, L. A., 3 Dec 2013, In: Bioscience Reports. 33, 6Research output: Contribution to journal › Article (Academic Journal) › peer-review
24 Citations (Scopus) -
2012
Down-regulation of myogenin can reverse terminal muscle cell differentiation
Mastroyiannopoulos, N., Nicolaou, P., Anayasa, M., Uney, J. & Phylactou, L., 3 Jan 2012, In: PLoS ONE. 7(1), p. e29896 - e29896 1 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
62 Citations (Scopus) -
MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex
Scott, H. L., Tamagnini, F., Narduzzo, K. E., Howarth, J. L., Bok-Lee, Y., Wong, L.-F., Brown, M. W., Warburton, E. C., Bashir, Z. I. & Uney, J. B., Oct 2012, In: European Journal of Neuroscience. 36, 7, p. 2941-8Research output: Contribution to journal › Article (Academic Journal) › peer-review
118 Citations (Scopus) -
MiR-3120 is a mirror microRNA that targets heat shock cognate protein 70 and auxilin messenger RNAs and regulates clathrin vesicle uncoating
Scott, H., Howarth, J., Lee, Y. B., Wong, L.-F., Bantounas, I., Phylactou, L., Verkade, P. & Uney, J. B., 27 Apr 2012, In: Journal of Biological Chemistry. 287, 18, p. 14726-14733 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
40 Citations (Scopus) -
Spatially controlling neuronal adhesion on CVD diamond
May, P. W., Regan, E. M., Taylor, A., Uney, J. B., Dick, A. D. & McGeehan, J. P., 2012, In: Diamond and Related Materials. 23, p. 100 5 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
37 Citations (Scopus) -
2011
Axotomy-induced miR-21 promotes axon growth in adult dorsal root ganglion neurons
Strickland, I., Holmes, F., Richards, L., Wynick, D., Uney, J. & Wong, L., 10 Aug 2011, In: PLoS ONE. 6, 8, p. e23423 - e23423 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
151 Citations (Scopus) -
Connexin 36 expression regulates neuronal differentiation from neural progenitor cells
Hartfield, E., Rinaldi, F., Glover, C., Wong, L., Caldwell, M. & Uney, J., Mar 2011, In: PLoS ONE. 9;6(3), p. e14746 - e14746 1 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
43 Citations (Scopus) -
Endogenous TWIST expression and differentiation are opposite during human muscle development
Koutsoulidou, A., Mastroyiannopoulos, N., Furling, D., Uney, J. & Phylactou, L., Dec 2011, In: Muscle and Nerve. 44(6), p. 984 - 986 3 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
6 Citations (Scopus) -
Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle
Koutsoulidou, A., Mastroyiannopoulos, N., Furling, D., Uney, J. B. & Phylactou, L., 7 Jun 2011, In: BMC Developmental Biology. 11, 9 p., 34.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile151 Citations (Scopus)279 Downloads (Pure) -
Fusion between human mesenchymal stem cells and rodent cerebellar Purkinje cells
Kemp, K., Gordon, D., Wraith, D., Mallam, E., Hartfield, E., Uney, J., Wilkins, A. & Scolding, N., Feb 2011, In: Neuropathology and Applied Neurobiology. 37, p. 166 - 178Research output: Contribution to journal › Article (Academic Journal) › peer-review
67 Citations (Scopus) -
Spatially controlling neuronal adhesion and inflammatory reactions on implantable diamond
Regan, E. M., Taylor, A., May, P. W., Uney, J. B., Dick, A. D. & McGeehan, J. P., Dec 2011, In: IEEE Journal of Emerging and Selected Topics in Circuits and Systems. 1 , 4, p. 557 - 565 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile9 Citations (Scopus)541 Downloads (Pure) -
2010
BAG-1 enhances cell-cell adhesion, reduces proliferation and induces chaperone-independent suppression of hepatocyte growth factor-induced epidermal keratinocyte migration
Hinitt, C., Wood, J., Lee, S., Williams, A., Howarth, J., Glover, C., Uney, J. & Hague, A., 1 Aug 2010, In: Experimental Cell Research. 316, 13, p. 2042 - 2060 19 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
11 Citations (Scopus) -
Differential patterning of neuronal, glial and neural progenitor cells on phosphorus-doped and UV irradiated diamond-like carbon
Regan, E., Uney, J., Dick, A., Zhang, Y., Nunez-Yanez, J., McGeehan, J., Claeyssens, F. & Kelly, S., Jan 2010, In: Biomaterials. 31, 2, p. 207 - 215 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
41 Citations (Scopus) -
Human mesenchymal stem cells infiltrate the spinal cord, reduce demyelination, and localize to white matter lesions in experimental autoimmune encephalomyelitis
Gordon, D., Pavlovska, G., Uney, J., Wraith, D. & Scolding, N., Nov 2010, In: Journal of Neuropathology and Experimental Neurology. 69, 11, p. 1087 - 1095 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
79 Citations (Scopus) -
The Application of Ribozymes and DNAzymes in Muscle and Brain
Mastroyiannopoulos, N. P., Uney, J. B. & Phylactou, L. A., Aug 2010, In: Molecules. 15, 8, p. 5460-5472 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile12 Citations (Scopus)217 Downloads (Pure) -
Using viral vectors as gene transfer tools (Cell Biology and Toxicology Special Issue: ETCS-UK 1 day meeting on genetic manipulation of cells)
Howarth, J., Lee, Y. & Uney, J., Feb 2010, In: Cell Biology and Toxicology. 26 (1), p. 1 - 20Research output: Contribution to journal › Article (Academic Journal) › peer-review
66 Citations (Scopus) -
2009
HSP70 interacting protein prevents the accumulation of inclusions in polyglutamine disease
Howarth, J., Glover, C. & Uney, J., Feb 2009, In: Journal of Neurochemistry. 108, p. 945 - 951 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
25 Citations (Scopus) -
Identifying neural progenitor cells in the adult brain
Kelly, S., Caldwell, M., Keasey, M., Cooke, J. & Uney, J., 2009, In: Methods in Molecular Biology. 549, p. 217 - 230Research output: Contribution to journal › Article (Academic Journal) › peer-review
1 Citation (Scopus) -
Prolyl oligopeptidase binds to GAP-43 and functions without its peptidase activity
Di Daniel, E., Glover, C., Grot, E., Chan, M., Sanderson, T., White, J., Ellis, C., Gallagher, K., Uney, J., Thomas, J., Maycox, P. & Mudge, A., Jul 2009, In: Molecular and Cellular Neuroscience. 41 (3), p. 373 - 382Research output: Contribution to journal › Article (Academic Journal) › peer-review
85 Citations (Scopus) -
Twist-1 regulates the miR-199a/214 cluster during development
Lee, Y., Bantounas, I., Lee, D., Phylactou, L., Caldwell, M. & Uney, J., Jan 2009, In: Nucleic Acids Research. 37, 1, p. 123 - 128 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
197 Citations (Scopus) -
2008
Arteriolar genesis and angiogenesis induced by endothelial nitric oxide synthase overexpression results in a mature vasculature
Benest, A. V., Stone, O. A., Millar, W. H., Glover, C. J., Uney, J., Baker, A. H., Harper, S. J. & Bates, D., Aug 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 8, p. 1462 - 1468 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
36 Citations (Scopus) -
Enhanced green fluorescent protein-expressing human mesenchymal stem cells retain neural marker expression
Gordon, D., Glover, C. P., Merrison, A. M., Uney, J. B. & Scolding, N. J., Jan 2008, In: Journal of Neuroimmunology. 193, 1-2, p. 59-67 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
14 Citations (Scopus) -
Expression of long-term depression underlies visual recognition memory
Griffiths, S., Scott, H., Glover, C., Bienemann, A., Ghorbel, M., Uney, J., Brown, M., Warburton, E. & Bashir, Z., 24 Apr 2008, In: Neuron. 58, 2, p. 186 - 194 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
133 Citations (Scopus) -
Hsp 70 Suppresses Apoptosis In Sympathetic Neurons By Preventing the Activation Of C-Jun
Bienemann, A., Lee, Y., Howarth, J. & Uney, J., Jan 2008, In: Journal of Neurochemistry. 104, p. 271 - 278 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
28 Citations (Scopus) -
Human mesenchymal stem cells abrogate experimental allergic encephalomyelitis after intraperitoneal injection and with sparse CNS infiltration
Gordon, D., Pavlovska, G., Glover, C., Uney, J., Wraith, D. & Scolding, N., Dec 2008, In: Neuroscience Letters. 448, p. 71 - 73 3 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
99 Citations (Scopus) -
Patterned growth of neuronal cells on modified diamond-like carbon substrates
Kelly, S., Regan, E., Uney, J., Dick, A., McGeehan, J., The Bristol Biochip, G., Mayer, E. & Claeyssens, F., Jun 2008, In: Biomaterials. 29, 17, p. 2573 - 2580 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
59 Citations (Scopus) -
The effect of myotonic dystrophy transcript levels and location on muscle differentiation
Mastroyiannopoulos, N. P., Chrysanthou, E., Kyriakides, T. C., Uney, J. B., Mahadevan, M. S. & Phylactou, L. A., 12 Dec 2008, In: Biochemical and Biophysical Research Communications. 377, 2, p. 526-31 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
7 Citations (Scopus) -
Twist induces reversal of myotube formation
Hjiantoniou, E., Anayasa, M., Nicolaou, P., Bantounas, I., Saito, M., Iseki, S., Uney, J. B. & Phylactou, L. A., Feb 2008, In: Differentiation. 76, 2, p. 182-92 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
31 Citations (Scopus) -
2007
A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis
Chan, C. W., Lee, Y. B., Uney, J., Flynn, A., Tobias, J. H. & Norman, M., Nov 2007, In: International Journal of Biochemistry and Cell Biology. 407, 3, p. 355 - 362 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
27 Citations (Scopus) -
Hsp40 Molecules That Target to the Ubiquitin-proteasome System Decrease Inclusion Formation in Models of Polyglutamine Disease
Howarth, J., Kelly, S., Keasey, M., Glover, C., Lee, Y., Mitrophanous, K., Gallo, J., Chapple, J., Cheetham, M. & Uney, J., Jun 2007, In: Molecular Therapy. 15 (6), p. 1100 - 1105 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
89 Citations (Scopus)