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Professor Jan FrayneB.Sc.(Nott.), Ph.D.(Bristol)

Professor in Molecular Cell Biology

11 - 20 out of 71Page size: 10
  1. 2016
  2. Published

    Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants

    Perkins, A., Xu, X., Higgs, D., Patrinos, G. P., Arnaud, L., Bieker, J. J., Philipsen, S. & KLF1 Consensus Workgroup, 14 Apr 2016, In : Blood. 127, 15, p. 1856-1862 7 p.

    Research output: Contribution to journalArticle

  3. 2014
  4. Published

    Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL

    Trakarnsanga, K., Wilson, M. C., Lau, W. W. Y., Singleton, B. K., Parsons, S. F., Sakuntanaga, P., Kurita, R., Nakamura, Y., Anstee, D. J. & Frayne, J., 2014, In : Haematologica. Aug 8. pii: haematol.2014.110155.

    Research output: Contribution to journalArticle

  5. Published

    Qualitative and Quantitative Comparison of the Proteome of Erythroid Cells Differentiated from Human iPSCs and Adult Erythroid Cells by Multiplex TMT Labelling and NanoLC-MS/MS

    Trakarnsanga, K., Wilson, M. C., Griffiths, R. E., Toye, A. M., Carpenter, L., Heesom, K. J., Parsons, S. F., Anstee, D. J. & Frayne, J., 2014, In : PLoS ONE. 9, 7, p. e100874

    Research output: Contribution to journalArticle

  6. 2013
  7. Published

    Epididymal specific, selenium-independent GPX5 protects cells from oxidative stress-induced lipid peroxidation and DNA mutation

    Taylor, A., Robson, A., Houghton, B. C., Jepson, C. A., Ford, W. C. L. & Frayne, J., Sep 2013, In : Human Reproduction. 28, 9, p. 2332-2342 11 p.

    Research output: Contribution to journalArticle

  8. 2012
  9. Published

    Blood group phenotypes resulting from mutations in erythroid transcription factors.

    Singleton, B. K., Frayne, J. & Anstee, D. J., Nov 2012, In : Current Opinion in Hematology. 19, 6, p. 486-493 8 p.

    Research output: Contribution to journalArticle

  10. 2011
  11. Published

    Mutations in the second zinc finger of human EKLF reduce promoter affinity but give rise to benign and disease phenotypes

    Singleton, BK., Lau, W., Fairweather, VS., Burton, NM., Wilson, MC., Parsons, SF., Richardson, BM., Trakarnsanga, K., Brady, RL., Anstee, DJ. & Frayne, J., Jul 2011, In : Blood. 118, p. 3137 - 3145 9 p.

    Research output: Contribution to journalArticle

  12. Published

    Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS

    Chaikuad, A., Shafqat, N., Al-Mokhtar, R., Cameron, G., Clarke, AR., Brady, RL., Oppermann, U., Frayne, J. & Yue, WW., Apr 2011, In : Biochemical Journal. 435 (2), p. 401 - 409 11 p.

    Research output: Contribution to journalArticle

  13. 2009
  14. Published

    A Novel EKLF Mutation in a Patient with Dyserythropoietic Anemia: The First Association of EKLF with Disease in Man.

    Singleton, B. K., Fairweather, V. S. S., Lau, W., Parsons, S. F., Burton, N. M., Frayne, J., Brady, R. L. & Anstee, D. J., 20 Nov 2009, In : Blood. 114, 22, p. 72-72 1 p.

    Research output: Contribution to journalArticle

  15. Published

    Analysis of the differential proteome of human erythroblasts during in vitro erythropoiesis by 2-D DIGE

    Richardson, BM., Heesom, KJ., Parsons, SF., Anstee, DJ. & Frayne, J., Sep 2009, In : Proteomics - Clinical applications. 3 (9), p. 1123 - 1134 12 p.

    Research output: Contribution to journalArticle

  16. Published

    Structure of insoluble rat sperm glyceraldehyde-3-phosphate dehydrogenase (GAPDH) via heterotetramer formation with Escherichia coli GAPDH reveals target for contraceptive design

    Frayne, J., Taylor, A., Cameron, G. & Hadfield, AT., Aug 2009, In : Journal of Biological Chemistry. 284 (34), p. 22703 - 22712 10 p.

    Research output: Contribution to journalArticle