Professor Jan Frayne

B.Sc.(Nott.), Ph.D.(Bristol)

  • BS8 1TD

1992 …2020

Research output per year

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Research Output

  • 62 Article (Academic Journal)
  • 8 Conference Contribution (Conference Proceeding)
  • 1 Chapter in a book
1992

Binding of a biotinylated oxytocin ligand in the rat testis

Frayne, J. & Nicholson, HD., 1992, In : Journal of Reproduction and Fertility Abstract Series. 10, p. 30 - 30 1 p.

Research output: Contribution to journalArticle (Academic Journal)

1993

Selective destruction of germ cells alters the concentrations of oxytocin in the interstitial and tubular fluid of the rat

Greenfield, H., Frayne, J. & Nicholson, HD., 1993, In : Journal of Reproduction and Fertility Abstract Series. Abs.Ser.11, p. 61 - 62 1 p.

Research output: Contribution to journalArticle (Academic Journal)

1994

Effects of LH and cell density on oxytocin production by isolated leydig cells in vitro

Frayne, J. & Nicholson, HD., 1994, Unknown. p. 39 - 39 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Evidence that testicular oxytocin is regulated by pachytene spermatocytes

Nicholson, HD. & Frayne, J., 1994, British Andrology Society.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Immunolocalisation of oxytocin in the epidymis of the rat

Harris, GC., Frayne, J. & Nicholson, HD., 1994, British Andrology Society.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

MHC Class 11 positive cells and T cells in the equine endometrium throughout the oestrous cycle

Frayne, J. & Stokes, CR., 1994, In : Veterinary Immunology and Immunopathology. 41, p. 55 - 72 17 p.

Research output: Contribution to journalArticle (Academic Journal)

17 Citations (Scopus)

Regulation of oxytocin production by purified adult rat leydig cells in vitro: effects of LH, testosterone and lipoproteins

Frayne, J. & Nicholson, HD., 1994, In : Journal of Endocrinology. 143, p. 325 - 332 7 p.

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)

The effect of germ cell complement on the presence of oxytocin in the interstitial and seminiferous tubule fluid of the rat testis

Nicholson, HD., Greenfield, HM. & Frayne, J., 1994, In : Journal of Endocrinology. 143, p. 471 - 478 7 p.

Research output: Contribution to journalArticle (Academic Journal)

17 Citations (Scopus)

The effect of oxytocin and a specific oxytocin antagonist on testosterone production by adult rat leydig cells in vitro

Frayne, J., Havard, NA. & Nicholson, HD., 1994, Unknown. Vol. 13. p. 34 - 35 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

1995

Detection of tetanus toxoid-specific memory T cells in equine lymph nodes but not in peripheral blood.

Frayne, J. & Stokes, C. R., 1995, In : Research in Veterinary Science. 59, 1, p. 79-81

Research output: Contribution to journalArticle (Academic Journal)

5 Citations (Scopus)

Effect of oxytocin on testosterone production by isolated rat Leydig cells is mediated via a specific oxytocin receptor

Frayne, J. & Nicholson, HD., 1995, In : Biology of Reproduction. 52, p. 1268 - 1273

Research output: Contribution to journalArticle (Academic Journal)

46 Citations (Scopus)

Evidence that testicular oxytocin is regulated by pachytene spermatocytes

Frayne, J. & Nicholson, HD., 1995, In : International Journal of Andrology. 18

Research output: Contribution to journalArticle (Academic Journal)

Immunolocalisation of oxytocin in the epididymis of the rat

Harris, GC., Frayne, J. & Nicholson, HD., 1995, In : International Journal of Andrology. 18

Research output: Contribution to journalArticle (Academic Journal)

The presence of testicular oxytocin is regulated by the spermatogenic cycle

Frayne, J. & Nicholson, HD., 1995, In : Journal of Reproduction and Fertility Abstract Series. 15, p. 54 - 54 1 p.

Research output: Contribution to journalArticle (Academic Journal)

1996

Effects of oxytocin on sperm transport in the pubertal rat

Frayne, J., Townsend, D. & Nicholson, HD., 1996, In : Journal of Reproduction and Fertility. 107, p. 299 - 306

Research output: Contribution to journalArticle (Academic Journal)

25 Citations (Scopus)

Epididymal oxytocin in the rat: its origin and control

Harris, GC., Frayne, J. & Nicholson, HD., 1996, In : International Journal of Andrology. 19, p. 278 - 286

Research output: Contribution to journalArticle (Academic Journal)

Epididymal oxytocin in the rat: its origin and regulation

Harris, GC. & Frayne, J., 1996, In : International Journal of Andrology. 19, p. 278 - 286

Research output: Contribution to journalArticle (Academic Journal)

21 Citations (Scopus)
1997

Cloning, sequencing and characterisation of rat fertilinβ

McLaughlin, EA., Barker, HL., Frayne, J., Ford, WCL., Jones, R. & Hall, L., 1997, In : Journal of Reproduction and Fertility Abstract Series. 19, p. 17 - 17 1 p.

Research output: Contribution to journalArticle (Academic Journal)

Cloning, sequencing and characterisation of rat fertilin β

McLaughlin, EA., Barker, HL., Frayne, J., Ford, WCL., Jones, R. & Hall, L., 1997, Unknown. Vol. 19. p. 28 - 28 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Cloning and sequence analysis of rat fertilin α and β-developmental expression, procesing and immunolocalisation

McLaughlin, EA., Frayne, J., Barker, HL., Jury, JA., Jones, R., Ford, WCL. & Hall, L., 1997, In : Molec. Hum. Reprod. 3, p. 801 - 809

Research output: Contribution to journalArticle (Academic Journal)

Rat MDC family of proteins: Sequence analysis, tissue distribution and expression in prepubertal and adult rat testis

Frayne, J., Jury, JA., Barker, HL. & Hall, L., 1997, In : Molecular Reproduction and Development. 48, p. 159 - 167

Research output: Contribution to journalArticle (Academic Journal)

34 Citations (Scopus)

Species differences in the distribution of oxytocin receptors in the male reproductive tract

Nicholson, HD. & Frayne, J., 1997, Montreal, Quebec. Plenum, p. 140 - 140 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

The distribution of oxytocin receptors in the human and monkey male reproductive tracts

Frayne, J., Mokete, M. & Nicholson, HD., 1997, Unknown. p. 38 - 38 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

The human fertilin α gene is non-functiona; implications for its proposed role in fertilisation

Jury, JA., Frayne, J. & Hall, L., 1997, In : Biochemical Journal. 321, p. 577 - 581

Research output: Contribution to journalArticle (Academic Journal)

1998

Expression of extracellular glutathione peroxidase type 5(GPX5) in the rat male reproductive tract

Williams, KM., Frayne, J. & Hall, L., 1998, In : Molecular Human Reproduction. 4, p. 841 - 848

Research output: Contribution to journalArticle (Academic Journal)

46 Citations (Scopus)

Expression of extracellular superoxide dismutase in the human male reproductive tract, detected using antisera raised against a recombinant protein

Williams, KM., Frayne, J., McLaughlin, EA. & Hall, L., 1998, In : Molecular Human Reproduction. 4, p. 235 - 242

Research output: Contribution to journalArticle (Academic Journal)

27 Citations (Scopus)

Expression of human epididymal glutathione peroxidase in the male reproductive tract.

K, W., Frayne, J. & Hall, L., Feb 1998, In : Boden Conference, Sydney, Australia, February 1998.

Research output: Contribution to journalArticle (Academic Journal)

71 Citations (Scopus)

Macaque MDC family of proteins: sequence analysis, tissue distribution and proteolytic processing in the male reproductive tract

Frayne, J., Jury, JA., Barker, HL., Perry, ACF., Jones, R. & Hall, L., 1998, In : Molec. Human Reprod. 4, p. 429 - 437

Research output: Contribution to journalArticle (Academic Journal)

26 Citations (Scopus)

Processing of macaque MDC proteins during epididymal transit

Frayne, J., Jury, JA., Barker, HL. & Hall, L., 1998, In : Boden Conference, Sydney, Australia, February 1998.

Research output: Contribution to journalArticle (Academic Journal)

Sequence analysis and characterisation of the rat orthologue of the TNF a converting enzyme (TACE)

Beaumont, AJ., Jury, JA., Frayne, J., Devos, R., Van Der Hayden, J., Jeffrey, L., Price, GJ. & Hall, L., 1998, Biochem Society 667th Annual Meeting, Leicester.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

42 Citations (Scopus)
42 Citations (Scopus)

The majority of human glutathione peroxidase type 5 (GPX5) transcripts are incorrectly spliced: implications for the role of GPX5 in the male reproductive tract

Hall, L., Williams, K., Perry, ACF., Frayne, J. & Jury, JA., 1998, In : Biochemical Journal. 333, p. 5 - 9

Research output: Contribution to journalArticle (Academic Journal)

61 Citations (Scopus)

The MDC family of proteins and their processing during epididymal transit

Frayne, J., Jury, JA., Barker, H. & Hall, L., 1998, In : Journal of Reproduction and Fertility. Suppl 53, p. 149 - 155

Research output: Contribution to journalArticle (Academic Journal)

19 Citations (Scopus)
1999

Effect of synthetic peptides on sperm binding and sperm-egg fusion in the mouse: identity of the putative integrin-binding motif

McLaughlin, EA., Frayne, J., Bloomberg, G. & Hall, L., 1999, In : Journal of Reproduction and Fertility Abstract Series. Abstract Series No 24, p. 8 - 9

Research output: Contribution to journalArticle (Academic Journal)

Localisation of phosphatidylethanolamine-binding protein in the brain and other tissues of the rat

Frayne, J., Ingram, CD., Love, S. & Hall, L., 1999, In : Cell and Tissue Research. 298, p. 415 - 423

Research output: Contribution to journalArticle (Academic Journal)

52 Citations (Scopus)

Mammalian sperm-egg recognition: does fertilin β have a major role to play?

Frayne, J. & Hall, L., 1999, In : BioEssays. 21, p. 183 - 187

Research output: Contribution to journalArticle (Academic Journal)

17 Citations (Scopus)

Non-functional fertility genes in humans: contributory factors in reduced male fertility?

Hall, L. & Frayne, J., 1999, In : Human Fertility. 2, p. 36 - 41

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)

The potential use of sperm antigens as targets for immunocontraception; past, present and future

Hall, L. & Frayne, J., 1999, In : Journal of Reproductive Immunology. 43, p. 1 - 33

Research output: Contribution to journalArticle (Academic Journal)

44 Citations (Scopus)

Transcripts encoding the sperm surface protein tMDC II are non-functional in the human

Frayne, J., Dimsey, EAC., Jury, JA. & Hall, L., 1999, In : Biochemical Journal. 341, p. 771 - 775

Research output: Contribution to journalArticle (Academic Journal)

17 Citations (Scopus)
2001
22 Citations (Scopus)
2002
39 Citations (Scopus)

Fertilin

Hall, L. & Frayne, J., 2002, Wiley Encyclopedia of Molecular Medicine. Creighton, TE. (ed.). John Wiley & Sons, Inc, p. 1265 - 1268

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

Human tMDC III: a sperm protein with a potential role in oocyte recognition

Frayne, J., Hurd, EAC. & Hall, L., Sep 2002, In : Molecular Human Reproduction. 8 (9), p. 817 - 822 6 p.

Research output: Contribution to journalArticle (Academic Journal)

14 Citations (Scopus)