Photo of Jennifer R Bailey

Dr Jennifer R Bailey

PhD, BSc (Hons)

  • BS40 5DU

20072020

Research output per year

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Personal profile

Research interests

The focus of my research is inflammatory bowel disease (IBD), in particular factors which cause the development of inflammation-induced fibrosis and therapeutic anti-inflammatory agents. There are two arms to my work:

1) An iron-responsive probiotic. This project is developing an iron and stress-responsive probiotic for use in treating inflammatory bowel disease in animals and humans. Work is ongoing to further assess the anti-inflammatory properties of this probiotic and determine how these can best be harnessed to treat disease.

 

Science Yoghurt

 

2) The role of IL-13 in the development of fibrotic strictures in Crohn's disease. IL-13 is known to have a role in fibrosis. I have found it to be increased in the intestines of Crohn's disease patients and have identified a novel population of cells, showing some characteristics of innate lymphoid cells, which are able to produce IL-13 and are abundant in fibrotic intestinal muscle. Work is ongoing to further characterise these cells and assess their potential as a therapeutic target.

 

 ILC Pure

 

Further information about Dr Jenny Bailey can be found here.

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Projects

Research Output

  • 9 Article (Academic Journal)
  • 1 Conference Poster
  • 1 Patent

Dietary putrescine supplementation reduces faecal abundance of Clostridium perfringens and markers of inflammation in captive azure-winged magpies

Harrold, D., Saunders, R. A. & Bailey, J. R., 6 Feb 2020, (Accepted/In press) In : Journal of Zoo and Aquarium Research.

Research output: Contribution to journalArticle (Academic Journal)

  • The Mycotoxin Deoxynivalenol Significantly Alters the Function and Metabolism of Bovine Kidney Epithelial Cells In Vitro

    Bailey, J. R., Breton, J., Panic, G., Cogan, T. A., Bailey, M., Swann, J. & Lee, M. RF., 20 Sep 2019, In : Toxins. 11, 10, 13 p., 554.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 162 Downloads (Pure)

    Editorial: Factors Promoting Development of Fibrosis in Crohn's Disease

    Bailey, J., 26 Sep 2017, In : Frontiers in Medicine. 4, p. 160

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
    208 Downloads (Pure)