Research output per year
Research output per year
Personal profile
Research interests
I am a senior biomedical scientist focusing on research in ocular immunology, immunoaging, and therapeutics, particularly gene therapy for chronic retinal diseases and associated metabolic disturbances. My research centers on uncovering the immune mechanisms behind age-related degenerative eye conditions and developing innovative therapeutic strategies to prevent or reverse disease progression. I have a track record of leading collaborative research and actively mentoring students at all levels and emerging scientists.
I also contribute to the scientific community as a reviewer for major funding bodies such as the MRC, and as a peer reviewer for leading journals, including Science Advances, Molecular Therapy, Autophagy, Journal of Neuroinflammation, Frontiers in Immunology, Frontiers in Cell and Developmental Biology, International Immunopharmacology, Investigative Ophthalmology & Visual Science, and iScience. Additionally, I serve as a topic editor for Frontiers in Immunology and Cells.
Keywords
- ageing
- innate immunity
- chronic inflammation
- autophagy
- cellular senescence
- induced pluripotent stem cells
- metabolism
- mitochondria
- macular degeneration
- diabetic retinopathy
- uveitis
- gene therapy
- small molecule therapy
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Age-Associated Decline in Autophagy Pathways in Retinal Pigment Epithelium and Protective Effects of Topical Trehalose in Light-induced Outer Retinal Degeneration in Mice
Cox, K., Shi, G., Read, N., Ou, K., Liu, Z., Wu, J., Cendanawati, S., Powell, J. L. B., Nicholson, L., Dick, A. D. & Liu, J., 18 Jan 2025Research output: Other contribution
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Marine bromophenols suppressed choroidal neovascularization by targeting HUWE1 through NF-κb signaling pathway
Ou, K., Li, Y., Wang, Y., Liu, J., Luo, Y., Jiang, J., Dan, J., Tang, D., Chen, Z. & Wu, J., 1 Feb 2024, In: International Journal of Biological Macromolecules. 257, Part 1, 128620.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
On implications of somatostatin in diabetic retinopathy
Fang, Y., Wang, Q., Li, Y., Zeng, L., Liu, J. & Ou, K., 1 Sept 2024, In: Neural Regeneration Research. 19, 9, p. 1984-1990 7 p.Research output: Contribution to journal › Review article (Academic Journal) › peer-review
Open Access1 Citation (Scopus)
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Combination therapy for dry AMD: targeting systemic and local inflammation synergistically with oral metformin and subretinal IRAK3 gene delivery
Liu, J. (Principal Investigator)
6/01/25 → 5/01/26
Project: Research
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Regulating systemic and local inflammation to shape high-fat diet-altered neuroretinal immune privilege
Liu, J. (Principal Investigator)
5/02/24 → 4/02/28
Project: Research
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A novel dual-target gene therapy for safe and efficacious treatment of chronic non-infectious uveitis
Liu, J. (Co-Investigator)
1/02/24 → 1/02/26
Project: Research
Datasets
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Data from: Fossil embryos from the Middle and Late Cambrian period of Hunan, south China
Dong, X.-P. (Contributor), Donoghue, P. C. J. (Contributor), Cheng, H. (Contributor) & Liu, J.-B. (Contributor), Dryad, 30 Oct 2012
DOI: 10.5061/dryad.f3050, http://datadryad.org/stash/dataset/doi:10.5061/dryad.f3050
Dataset
Activities
- 1 Participation in workshop, seminar, course
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Global Sustainable Farming Systems Workshop
Liu, J. (Participant)
28 May 2013 → 29 May 2013Activity: Participating in or organising an event types › Participation in workshop, seminar, course