Dr Jian Liu

Search results

• 2021

  Cellular senescence in the aging retina and developments of senotherapies for age-related macular degeneration

  Lee, K. S., Lin, S., Copland, D. A., Dick, A. D. & Liu, J., 22 Jan 2021, In: Journal of Neuroinflammation. 18, 1, 32.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

• Quantitative Assessment of Experimental Ocular Inflammatory Disease

  Bradley, L. J., Ward, A., Hsue, M. C. Y., Liu, J., Copland, D. A., Dick, A. D. & Nicholson, L. B., 18 Jun 2021, In: Frontiers in Immunology. 12, 630022.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Eye Diseases 100%
  • Uveitis 52%
  • Inflammation 42%
  • Mite Infestations 38%
  • Artificial Intelligence 33%
  7 Downloads (Pure)
• 2020

  Treatment of diabetic retinopathy through neuropeptide Y-mediated enhancement of neurovascular microenvironment

  Ou, K., Copland, D. A., Theodoropoulou, S., Mertsch, S., Liu, J., Li, Y., Schrader, S., Liu, L. & Dick, A. D., 6 Mar 2020, In: Journal of Cellular and Molecular Medicine. 13 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Neuropeptide Y 100%
  • Diabetic Retinopathy 91%
  • Neuroglia 46%
  • Retinal Ganglion Cells 39%
  • Apoptosis 32%
  42 Downloads (Pure)

• Treatment with interleukin-33 is non-toxic and protects retinal pigment epithelium in an ageing model of outer retinal degeneration

  Clare, A. J., Copland, D. A., Nicholson, L. B., Liu, J., Neal, C. R., Moss, S., Dick, A. D. & Theodoropoulou, S., 20 Oct 2020, (E-pub ahead of print) In: Journal of Cellular and Molecular Medicine. 5 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Interleukin-33 100%
  • Retinal Degeneration 88%
  • Retinal Pigment Epithelium 82%
  • Macular Degeneration 38%
  • High Fat Diet 36%
  11 Downloads (Pure)
• 2019

  Corrigendum to "Restoring retinal neurovascular health via substance P" [Exp. Cell Res. (2019)]

  Ou, K., Mertsch, S., Theodoropoulou, S., Wu, J., Liu, J., Copland, D. A., Schrader, S., Liu, L. & Dick, A. D., 15 Sep 2019, In: Experimental Cell Research. 382, 2, 1 p., 111482.

  Research output: Contribution to journal › Comment/debate (Academic Journal) › peer-review

  • Substance P 100%
  • Health 46%

• Müller Cells Stabilize Microvasculature through Hypoxic Preconditioning.

  Ou, K., Mertsch, S., Theodoropoulou, S., Wu, J., Liu, J., Copland, D., Scott, L., Dick, A., Schrader, S. & Liu, L., 2019, In: Cellular Physiology and Biochemistry. 52, 4, p. 668-680 13 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Capillary Permeability 100%
  • Microvessels 91%
  • Endothelial Cells 67%
  • Vascular Endothelial Growth Factor A 52%
  • Smegmamorpha 46%
  116 Downloads (Pure)

• Restoring retinal neurovascular health via substance P

  Ou, K., Mertsch, S., Theodoropoulou, S., Wu, J., Liu, J., Copland, D., Schrader, S., Liu, L. & Dick, A., 15 Jul 2019, In: Experimental Cell Research. 380, 2, p. 115-123 9 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Substance P 100%
  • Retinal Ganglion Cells 86%
  • Vascular Endothelial Growth Factor A 64%
  • Capillary Permeability 61%
  • Aspartic Acid 58%
  6 Citations (Scopus)

  357 Downloads (Pure)
• 2018

  A Perspective of AMD Through the Eyes of Immunology

  Copland, D. A., Theodoropoulou, S., Liu, J. & Dick, A. D., 20 Jul 2018, In: Investigative Ophthalmology and Visual Science. 59, 4, p. AMD83-AMD92

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Allergy and Immunology 100%
  • Eye 57%
  • Inflammation 37%
  • Cellular Senescence 34%
  • Macular Degeneration 33%
  22 Citations (Scopus)
• 2017

  Evaluation of recombinant factor C assay for the detection of divergent lipopolysaccharide structural species and comparison with Limulus amebocyte lysate-based assays and a human monocyte activity assay

  Abate, W., Sattar, A. A., Liu, J., Conway, M. E. & Jackson, S. K., 12 Jul 2017, In: Journal of Medical Microbiology. 66, 7, p. 888-897 10 p., 000510.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • endotoxin binding proteins 100%
  • Horseshoe Crabs 92%
  • Human Activities 66%
  • Lipopolysaccharides 57%
  • Monocytes 55%
  15 Citations (Scopus)

  292 Downloads (Pure)

• Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study

  Wang, Y., Tian, G-B., Zhang, R., Shen, Y., Tyrrell, J. M., Huang, X., Zhou, H., Lei, L., Li, H-Y., Doi, Y., Fang, Y., Ren, H., Zhong, L-L., Shen, Z., Zeng, K-J., Wang, S., Liu, J-H., Wu, C., Walsh, T. R. & Shen, J., 1 Apr 2017, In: Lancet Infectious Diseases. 17, 4, p. 390-399 10 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Molecular Epidemiology 100%
  • Enterobacteriaceae 95%
  • Epidemiologic Studies 70%
  • China 70%
  • Escherichia coli 59%
• 2016

  Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis

  Liu, J., Copland, D. A., Theodoropoulou, S., Chiu, H. A. A., Barba, M. D., Mak, K. W., Mack, M., Nicholson, L. B. & Dick, A. D., 5 Feb 2016, In: Scientific Reports. 6, 15 p., 20639.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Inflammasomes 100%
  • Retinal Pigment Epithelium 93%
  • Macrophage Activation 92%
  • Autophagy 79%
  • Macrophages 39%
  39 Citations (Scopus)

  285 Downloads (Pure)

• Interleukin-33 regulates tissue remodelling and inhibits angiogenesis in the eye

  Theodoropoulou, S., Copland, D. A., Liu, J., Wu, J., Gardner, P. J., Ozaki, E., Doyle, S. L., Campbell, M. & Dick, A. D., 16 Dec 2016, In: Journal of Pathology. 241, 1, p. 45–56 12 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Interleukin-33 100%
  • Macular Degeneration 61%
  • Eye 44%
  • Retinal Pigment Epithelium 33%
  • Interleukin-1 Receptor-Like 1 Protein 25%
  33 Citations (Scopus)

  372 Downloads (Pure)

• Pleiotropic action of CpG-ODN on endothelium and macrophages attenuates angiogenesis through distinct pathways

  Wu, J., Su, W., Powner, M. B., Liu, J., Copland, D. A., Fruttiger, M., Madeddu, P., Dick, A. D. & Liu, L., 25 Aug 2016, In: Scientific Reports. 6, 15 p., 31873.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  Open Access

  File

  • Guanine Nucleotides 100%
  • Oligodeoxyribonucleotides 97%
  • Cytosine 96%
  • Endothelium 71%
  • Macrophages 56%
  10 Citations (Scopus)

  427 Downloads (Pure)
• 2015

  Activated adult microglia influence retinal progenitor cell proliferation and differentiation toward recoverin-expressing neuron-like cells in a co-culture model

  Xu, Y., Balasubramaniam, B., Copland, D. A., Liu, J., Armitage, M. J. & Dick, A. D., 14 Feb 2015, In: Graefe's Archive for Clinical and Experimental Ophthalmology.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Recoverin 100%
  • Microglia 63%
  • Coculture Techniques 61%
  • Cell Differentiation 50%
  • Stem Cells 45%
  9 Citations (Scopus)

• IL-4 Regulates Specific Arg-1(+) Macrophage sFlt-1-Mediated Inhibition of Angiogenesis

  Wu, W-K., Georgiadis, A., Copland, D. A., Liyanage, S., Luhmann, U. F. O., Robbie, S. J., Liu, J., Wu, J., Bainbridge, J. W., Bates, D. O., Ali, R. R., Nicholson, L. B. & Dick, A. D., 12 Jun 2015, In: American Journal of Pathology.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Vascular Endothelial Growth Factor Receptor-1 100%
  • Interleukin-4 70%
  • Inhibition (Psychology) 56%
  • Macrophages 53%
  • Choroidal Neovascularization 40%
  25 Citations (Scopus)

• Role of interleukin 33/ST2 axis in the immune-mediated pathogenesis of age-related macular degeneration

  Theodoropoulou, S., Copland, D. A., Liu, J. & Dick, A. D., 26 Feb 2015, In: Lancet. 385, Supplement 1, p. S97

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Interleukin-33 100%
  • Macular Degeneration 76%
  • Retinal Pigment Epithelium 55%
  • Mast Cells 46%
  • Toll-Like Receptors 39%
• 2013

  CD200R signaling inhibits pro-angiogenic gene expression by macrophages and suppresses choroidal neovascularization

  Horie, S., Robbie, S. J., Liu, J., Wu, W-K., Ali, R. R., Bainbridge, J. W., Nicholson, L. B., Mochizuki, M., Dick, A. D. & Copland, D. A., 2013, In: Scientific Reports. 3, p. 3072

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Choroidal Neovascularization 100%
  • Macrophages 56%
  • Gene Expression 48%
  • Dinoprostone 33%
  • Phenotype 27%
  28 Citations (Scopus)

• Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice

  Liu, J., Copland, D. A., Horie, S., Wu, W-K., Chen, M., Xu, Y., Paul Morgan, B., Mack, M., Xu, H., Nicholson, L. B. & Dick, A. D., 2013, In: PLoS ONE. 8, 8, p. e72935

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Arginase 100%
  • arginase 99%
  • angiogenesis 93%
  • Retinal Pigments 93%
  • Retinal Pigment Epithelium 87%
  66 Citations (Scopus)
• 2012

  Dog Ownership during Pregnancy, Maternal Activity, and Obesity: A Cross-Sectional Study

  Westgarth, C., Liu, J., Heron, J., Ness, A., Bundred, P., Gaskell, RM., German, AJ., McCune, S. & Dawson, S., Jan 2012, In: PLoS ONE. 7

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • ownership 100%
  • Ownership 98%
  • cross-sectional studies 93%
  • obesity 86%
  • dogs 61%
  15 Citations (Scopus)

• Persistent inflammation subverts thrombospondin-1-induced regulation of retinal angiogenesis and is driven by CCR2 ligation

  Chen, MZ., Copland, DA., Zhao, J., Liu, J., Forrester, J., Dick, AD. & Xu, H., Jan 2012, In: American Journal of Pathology. 180, 1, p. 235-45 11 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Thrombospondin 1 100%
  • Ligation 65%
  • Arginase 48%
  • Retina 48%
  • Inflammation 44%
  43 Citations (Scopus)

• Therapeutic dosing of fingolimod (FTY720) prevents cell infiltration, rapidly suppresses ocular inflammation, and maintains the blood-ocular barrier

  Copland, D. A., Liu, J., Schewitz-Bowers, L. P., Brinkmann, V., Anderson, K., Nicholson, L. B. & Dick, A. D., Feb 2012, In: American Journal of Pathology. 180, 2, p. 672 - 681 10 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Fingolimod Hydrochloride 100%
  • Eye 44%
  • Inflammation 42%
  • Multiple Sclerosis 23%
  • Lysosphingolipid Receptors 12%
  36 Citations (Scopus)
• 2011

  Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness

  Sood, A., Salih, S., Roh, D., Lacharme Lora, L., Parry, M. C., Hardiman, B., Keehan, R., Grummer, R., Winterhager, E., Gokhale, P. J., Andrews, P. W., Abbott, C., Forbes, K., Westwood, M., Aplin, J. D., Ingham, E., Papageorgiou, I., Berry, M., Liu, J., Dick, A. D. & 19 others, Garland, R. J., Williams, N., Singh, R., Simon, A. K., Lewis, M., Ham, J., Roger, L., Baird, D. M., Crompton, L. A., Caldwell, M. A., Swalwell, H., Birch-Machin, M., Lopez-Castejon, G., Randall, A., Lin, H., Suleiman, M-S., Evans, W. H., Newson, R. & Case, C. P., Dec 2011, In: Nature Nanotechnology. 6, 12, p. 824 - 833 9 p.

  Research output: Contribution to journal › Article (Academic Journal) › peer-review

  • Cytokines 100%
  • DNA 61%
  • Nanoparticles 60%
  • deoxyribonucleic acid 54%
  • damage 42%
  83 Citations (Scopus)
• 2005

  Global Interconnect Analysis

  Nurmi, T., Liu, J., Pamunuwa, D., Ahonen, T., Zheng, L-R., Isoaho, J. & Tenhunen, H., 2005, Interconnect-Centric Design for Advanced SoC and NoC. Nurmi, J., Tenhunen, H., Isoaho, J. & Jantsch, A. (eds.). Springer US, p. 55-84 30 p.

  Research output: Chapter in Book/Report/Conference proceeding › Other chapter contribution
  1 Citation (Scopus)