Research Output per year
Research Output
2020
A heterodimeric SNX4:SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly
Anton, Z., Betin, V. M. S., Simonetti, B., Traer, C. J., Attar, N., Cullen, P. J. & Lane, J. D., 15 Jul 2020, In : Journal of Cell Science. 133, 14, 38 p., jcs246306.Research output: Contribution to journal › Article (Academic Journal)
Open Access
File
A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons
Stathakos, P., Jiménez Moreno, N., Crompton, L. A., Nistor, P. A., Badger, J. L., Barbuti, P. A., Kerrigan, T. L., Randall, A. D., Caldwell, M. A. & Lane, J. D., 23 Jan 2020, (Accepted/In press) In : Autophagy.Research output: Contribution to journal › Article (Academic Journal)
2019
DNA damage signalling from the placenta to foetal blood as a potential mechanism for childhood leukaemia initiation
Mansell, E., Zareian, N., Malouf, C., Kapeni, C., Brown, N., Badie, C., Baird, D., Lane, J. D., Ottersbach, K., Blair, A. & Case, C. P., 13 Mar 2019, In : Scientific Reports. 9, 1, 17 p., 4370.Research output: Contribution to journal › Article (Academic Journal)
Open Access
File
Imaging Autophagy in hiPSC-Derived Midbrain Dopaminergic Neuronal Cultures for Parkinson’s Disease Research
Stathakos, P., Jimenez Moreno, N., Crompton, L., Nistor, P., Caldwell, M. & Lane, J., 5 Jan 2019, Autophagy. Humana Press, p. 257-280 23 p. (Methods in Molecular Biology).Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
Open Access
File
Mathematical Modeling Highlights the Complex Role of AKT in TRAIL-Induced Apoptosis of Colorectal Carcinoma Cells
Anderson, M. W., Moss, J., Szalai, R. & Lane, J., 22 Feb 2019, In : iScience. 12, p. 182-193 36 p.Research output: Contribution to journal › Article (Academic Journal)
Open Access
File
2018
Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes
Hawkins, S. J., Crompton, L. A., Sood, A., Saunders, M., Boyle, N. T., Buckley, A., Minogue, A. M., McComish, S. F., Jiménez-Moreno, N., Cordero-Llana, O., Stathakos, P., Gilmore, C. E., Kelly, S., Lane, J. D., Case, C. P. & Caldwell, M. A., 2 Apr 2018, In : Nature Nanotechnology. p. 427-433 7 p.Research output: Contribution to journal › Article (Academic Journal)
Open Access
File
Transautophagy: Research and Translation of Autophagy Knowledge
Lane, J., Albertini, M., Proikas-Cezanne, T., Engedal, N. & Zerovnik, E., 16 May 2018, In : Oxidative medicine and cellular longevity. 2018, 3 p.Research output: Contribution to journal › Editorial (Academic Journal)
2017
Induced Pluripotent Stem Cell Neuronal Models for the Study of Autophagy Pathways in Human Neurodegenerative Disease
Jimenez Moreno, N., Stathakos, P., Caldwell, M. A. & Lane, J., Sep 2017, In : Cells. 6, 3, 27 p., 24.Research output: Contribution to journal › Article (Academic Journal)
Open Access
File
Self-eating on demand: autophagy in cancer and cancer therapy
Lane, J. D. & Agostinis, P., 7 Dec 2017, In : Frontiers in Oncology. 7, DEC, 3 p., 302.Research output: Contribution to journal › Editorial (Academic Journal)
Open Access
File
Signalling mechanisms in autophagy: an introduction to the issue
Lane, J., 12 Dec 2017, In : Essays in Biochemistry.Research output: Contribution to journal › Editorial (Academic Journal)
Open Access
2015
Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells
Morgan, R. G., Molnar, E., Jones, R. F., Collard, T. J., Lane, J. D., Greenhough, A., Paraskeva, C. & Williams, A. C., 17 Feb 2015, In : British Journal of Cancer. 112, 4, p. 714-719 6 p.Research output: Contribution to journal › Article (Academic Journal)
Open Access
File
Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells
MacVicar, T., Mannack, L., Lees, R. M. & Lane, J., Jun 2015, In : International Journal of Molecular Sciences. p. 13356-13380 25 p.Research output: Contribution to journal › Special issue (Academic Journal)
The autophagosome: current understanding of formation and maturation
Mannack, L. V. J. & Lane, J. D., 16 Feb 2015, In : Research and Reports in Biochemistry. 2015, 5, p. 39-58 20 p.Research output: Contribution to journal › Review article (Academic Journal)
Open Access
File
USP30 deubiquitylates mitochondrial Parkin substrates and restricts apoptotic cell death
Liang, J-R., Lane, J., Mayor, U., Clague, M. & Urbe, S., 4 Mar 2015, In : EMBO Reports. 10 p.Research output: Contribution to journal › Article (Academic Journal)
2014
Impaired OMA1 dependent OPA1 cleavage and reduced DRP1 fission activity combine to prevent mitophagy in OXPHOS dependent cells
MacVicar, T. & Lane, J. D., 2014, In : Journal of Cell Science. p. 2313-2325 15.Research output: Contribution to journal › Article (Academic Journal)
Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions
Curtis, D. J., Sood, A., Phillips, T. E. J., Leinster, V. H. L., Nishiguchi, A., Coyle, C., Lacharme-Lora, L., Beaumont, O., Kemp, H., Goodall, R., Cornes, L., Giugliano, M., Barone, R. A., Matsusaki, M., Akashi, M., Tanaka, H. Y., Kano, M., McGarvey, J., Halemani, N. D., Simon, K. & 17 others, , 10 May 2014, In : Experimental Neurology.Research output: Contribution to journal › Article (Academic Journal)
2013
Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk
Petherick, K. J., Williams, A. C., Lane, J. D., Ordóñez-Morán, P., Huelsken, J., Collard, T. J., Smartt, H. J., Batson, J., Malik, K., Paraskeva, C. & Greenhough, A., 4 Jun 2013, In : EMBO Journal. 32, 13, p. 1903 - 1916 14 p.Research output: Contribution to journal › Article (Academic Journal)
Autophagy facilitates organelle clearance during differentiation of human erythroblasts: Evidence for a role for ATG4 paralogs during autophagosome maturation
Betin, V. M. S., Singleton, B. K., Parsons, S. F., Anstee, D. J. & Lane, J. D., Jun 2013, In : Autophagy. 9, 6, p. 881-893 13 p.Research output: Contribution to journal › Article (Academic Journal)
Influence of particle size and reactive oxygen species on cobalt chrome nanoparticle-mediated genotoxicity
Raghunathan, V. K., Devey, M., Hawkins, S., Hails, L., Davis, S. A., Mann, S., Chang, I. T., Ingham, E., Malhas, A., Vaux, D. J., Lane, J. D. & Case, C. P., May 2013, In : Biomaterials. 34, 14, p. 3559-3570 12 p.Research output: Contribution to journal › Article (Academic Journal)
SIRT3: A Central Regulator of Mitochondrial Adaptation in Health and Disease
Weir, H. J. M., Lane, J. D. & Balthasar, N., 2013, In : Genes & Cancer. 4, 3-4, p. 118-24Research output: Contribution to journal › Article (Academic Journal)
2012
A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress
Betin, VMS., MacVicar, TDB., Parsons, SF., Anstee, DJ. & Lane, JD., Apr 2012, In : Autophagy. 8(4), 13 p.Research output: Contribution to journal › Article (Academic Journal)
CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer's disease
Weir, H. J. M., Murray, T. K., Kehoe, P. G., Love, S., Verdin, E. M., O'Neill, M. J., Lane, J. D. & Balthasar, N., 6 Nov 2012, In : PLoS ONE. 7, 11, p. e48225 7 p., ARTN e48225.Research output: Contribution to journal › Article (Academic Journal)
Maturing reticulocytes internalize plasma membrane in glycophorin A-containing vesicles that fuse with autophagosomes before exocytosis
Griffiths, R. E., Kupzig, S., Cogan, N., Mankelow, T. J., Betin, V. M. S., Trakarnsanga, K., Massey, E. J., Lane, J. D., Parsons, S. F. & Anstee, D. J., 28 Jun 2012, In : Blood. 119, 26, p. 6296-6306 11 p.Research output: Contribution to journal › Article (Academic Journal)
The ins and outs of human reticulocyte maturation Autophagy and the endosome/exosome pathway
Griffiths, R. E., Kupzig, S., Cogan, N., Mankelow, T. J., Betin, V. M. S., Trakarnsanga, K., Massey, E. J., Parsons, S. F., Anstee, D. J. & Lane, J. D., Jul 2012, In : Autophagy. 8, 7, p. 1150-1151 2 p.Research output: Contribution to journal › Editorial (Academic Journal)
2010
Alternative macroautophagy
Klionsky, DJ. & Lane, JD., Feb 2010, In : Autophagy. 6, 2, p. 201 - 201 1 p.Research output: Contribution to journal › Article (Academic Journal)
Caspase cleavage of the Golgi stacking factor GRASP65 is required for Fas/CD95-mediated apoptosis
Cheng, JPX., Betin, VMS., Weir, H., Shelmani, GMA., Moss, DK. & Lane, JD., 2010, In : Nature. 1Research output: Contribution to journal › Article (Academic Journal)
Organelle dynamics and membrane trafficking in apoptosis and autophagy
Cheng, JPX. & Lane, JD., Nov 2010, In : Histology and Histopathology. 25 (11), p. 1457 - 1472 17 p.Research output: Contribution to journal › Article (Academic Journal)
10
Citations
(Scopus)
The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells
Patsos, HA., Greenhough, A., Hicks, DJ., Al kharusi, M., Collard, TJ., Lane, JD., Paraskeva, C. & Williams, AC., Jul 2010, In : International Journal of Oncology. 37 (5), p. 187 - 193 7 p.Research output: Contribution to journal › Article (Academic Journal)
2009
Alternative macroauotophagy
Klionsky, DJ. & Lane, JD., Feb 2009, In : Autophagy. 6 (2), p. 201 - 201 1 p.Research output: Contribution to journal › Article (Academic Journal)
Atg4D at the interface between autophagy and apoptosis
Betin, VMS. & Lane, JD., Oct 2009, In : Autophagy. 5 (7), p. 1057 - 1059 3 p.Research output: Contribution to journal › Article (Academic Journal)
Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondiral targetting and apoptosis
Betin, V. M. S. & Lane, J. D., Jul 2009, In : Journal of Cell Science. 122 , 14, p. 2554 - 2566 13 p.Research output: Contribution to journal › Article (Academic Journal)
Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase
Moss, DK., Wilde, A. & Lane, JD., Mar 2009, In : Journal of Cell Science. 122 (5), p. 644 - 655 12 p.Research output: Contribution to journal › Article (Academic Journal)
Nanoparticles can cause DNA damage across a cellular barrier
Bhabra, G., Sood, A., Fisher, B., Cartwright, L., Saunders, M. W., Evans, W. H., Surprenant, A., Lopez-Castejon, G., Mann, S., Davis, S. A., Hails, L. A., Ingham, E., Verkade, P., Lane, J., Heesom, K., Newson, R. & Case, C. P., Dec 2009, In : Nature Nanotechnology. 4, 12, p. 876 - 883 8 p.Research output: Contribution to journal › Article (Academic Journal)
2008
The cytoskeleton and the control of organelle dynamics in the apoptotic execution phase
Betin, VMS. & Lane, JD., 2008, The Eukaryotic Cell Cycle (SEB Experimental Biology Series, 59). Bryant, JA. & Francis, D. (eds.). Taylor & Francis Group, p. 267 - 283 17 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
1
Citation
(Scopus)
2006
A novel role for microtubules in apoptotic chromatin dynamics and cellular fragmentation
Moss, DK., Betin, VM., Malesinski, SD. & Lane, JD., Jun 2006, In : Journal of Cell Science. 119 (11), p. 2362 - 2374 13 p.Research output: Contribution to journal › Article (Academic Journal)
Microtubules: forgotten players in the apoptotic execution phase
Moss, DK. & Lane, JD., Jul 2006, In : Trends in Cell Biology. 16(7), p. 330 - 338 9 p.Research output: Contribution to journal › Article (Academic Journal)
40
Citations
(Scopus)
Transmitted light imaging
Lane, JD. & Stebbings, H., 2006, Methods Express: Cell Imaging. Stephens, D. (ed.). Chapter 4 ed. Scion Publishing Limited, p. 73 - 93 11 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
2005
Active relocation of chromatin and endoplasmic reticulum into blebs in late apoptic cells
Lane, JD., Allen, VJ. & Woodman, PG., Sep 2005, In : Journal of Cell Science. 118 (17), p. 4059 - 4071 13 p.Research output: Contribution to journal › Article (Academic Journal)
The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2
Patsos, HA., Hicks, DJ., Dobson, RRH., Greenhough, A., Woodman, N., Lane, JD., Williams, AC. & Paraskeva, C., Dec 2005, In : Gut. 54 (12), p. 1741 - 1750 10 p.Research output: Contribution to journal › Article (Academic Journal)
2004
Caspase-mediated cleavage of syntaxin 5 and giantin accompanies inhibition of secretory traffic during apoptosis
Lowe, M., Lane, JD., Woodman, PG. & Allan, VJ., 2004, In : Journal of Cell Science. 117, p. 1139 - 1150Research output: Contribution to journal › Article (Academic Journal)
60
Citations
(Scopus)
2002
Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis
Lane, JD., Lucocq, J., Pryde, J., Barr, FA., Woodman, PG., Allan, VJ. & Lowe, M., Feb 2002, In : Journal of Cell Biology. 156 (3), p. 495 - 509 15 p.Research output: Contribution to journal › Article (Academic Journal)
2001
Apoptotic cleavage of cytoplasmic dynein intermediate chain and p150Glued stops dynein-dependent membrane motility
Lane, JD., Maïlys, AS., Vergnolle, MAS., Woodman, PG. & Allan, VJ., Jun 2001, In : Journal of Cell Biology. 153 (7), p. 1415 - 1426 12 p.Research output: Contribution to journal › Article (Academic Journal)