Professor Jonathan P Clayden

MA, PhD, CChem, FRSC

  • BS8 1TS

1992 …2020

Research output per year

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Research Output

1992

Asymmetric epoxidations and kinetic resolutions of $-hydroxy allylic phosphine oxides

Clayden, J., Collington, E. W. & Warren, S., 1 Nov 1992, In : Tetrahedron Letters. 33, 46, p. 7043-7046 4 p.

Research output: Contribution to journalArticle (Academic Journal)

Asymmetric epoxidations and kinetic resolutions of δ-hydroxy allylic phosphine oxides

Clayden, J., Collington, E. W. & Warren, S., 10 Nov 1992, In : Tetrahedron Letters. 33, 46, p. 7043-7046 4 p.

Research output: Contribution to journalArticle (Academic Journal)

6 Citations (Scopus)

The synthesis of $-hydroxy allylic phosphine oxides by palladium(II)-catalysed allylic transposition

Clayden, J., Collington, E. W. & Warren, S., 1 Nov 1992, In : Tetrahedron Letters. 33, 46, p. 7039-7042 4 p.

Research output: Contribution to journalArticle (Academic Journal)

The synthesis of δ-hydroxy allylic phosphine oxides by palladium(II)-catalysed allylic transposition

Clayden, J., Collington, E. W. & Warren, S., 10 Nov 1992, In : Tetrahedron Letters. 33, 46, p. 7039-7042 4 p.

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)
1993

Alkenyl Oxazolidinones by Stereoselective Epoxidation of Delta-Hydroxy Allylic Phosphine Oxides - Synthesis of Any Isomer (Rr, Rs, Sr or Ss, E or Z) Bearing 1,4-Related Chiral Centers Across a Double-Bond

Clayden, J., COLLINGTON, E. W., LAMONT, R. B. & WARREN, S., 1993, In : Tetrahedron Letters. 34, 13, p. 2203-2206 4 p.

Research output: Contribution to journalArticle (Academic Journal)

Alkenyl oxazolidinones by stereoselective epoxidation of δ-hydroxy allylic phosphine oxides: Synthesis of any isomer (RR, RS, SR or SS; E or Z) bearing 1,4-related chiral centres across a double bond

Clayden, J., Collington, E. W., Lamount, R. B. & Warren, S., 26 Mar 1993, In : Tetrahedron Letters. 34, 13, p. 2203-2206 4 p.

Research output: Contribution to journalArticle (Academic Journal)

32 Citations (Scopus)

ortho-Substituted unsymmetrical biaryls from aryl tert-butyl sulfones

Clayden, J. & Julia, M., 1993, In : Journal of the Chemical Society: Chemical Communications. 22, p. 1682-1683 2 p.

Research output: Contribution to journalArticle (Academic Journal)

36 Citations (Scopus)

Stereochemical control (E/Z and syn/anti) by the diphenylphosphinoyl group in the synthesis of allylic alcohols by allylic rearrangement and by 1,4-diastereoselective reduction of enones

Clayden, J., Collington, E. W., Elliott, J., Martin, S. J., McElroy, A. B., Warren, S. & Waterson, D., 1993, In : Journal of the Chemical Society, Perkin Transactions 1. 16, p. 1849-1859 11 p.

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)

Stereocontrolled synthesis of R or S E or Z unsaturated α-amino acids by enantio- and diastereoselective epoxidation of δ-hydroxy allylic phosphine oxides

Clayden, J., Collington, E. W. & Warren, S., 19 Feb 1993, In : Tetrahedron Letters. 34, 8, p. 1327-1330 4 p.

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)

The Synthesis of Delta-Hydroxy Allylic Phosphine Oxides by Palladium(Ii)-Catalyzed Allylic Acetate Transposition

Clayden, J. & Warren, S., 1993, In : Journal of the Chemical Society, Perkin Transactions 1. 23, p. 2913-2923 11 p.

Research output: Contribution to journalArticle (Academic Journal)

The synthesis of δ-hydroxy allylic phosphine oxides by palladium(II)-catalysed allylic acetate transposition

Clayden, J. & Warren, S., 1 Dec 1993, In : Journal of the Chemical Society, Perkin Transactions 1. 23, p. 2913-2923 11 p.

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)
26 Citations (Scopus)

Asymmetric epoxidation and kinetic resolution of allylic phosphine oxides

Clayden, J. & Warren, S., 1994, In : Journal of the Chemical Society, Perkin Transactions 1. 19, p. 2811-2823 13 p.

Research output: Contribution to journalArticle (Academic Journal)

18 Citations (Scopus)

Diastereoselective epoxidation of allylic phosphine oxides

Clayden, J., Collington, E. W., Egert, E., McElroy, A. B. & Warren, S., 1994, In : Journal of the Chemical Society, Perkin Transactions 1. 19, p. 2801-2810 10 p.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

Homoallylic alcohols from samarium diiodide-mediated coupling of allylic sulfones with carbonyl compounds

Clayden, J. & Julia, M., 1994, In : Journal of the Chemical Society: Chemical Communications. 19, p. 2261-2262 2 p.

Research output: Contribution to journalArticle (Academic Journal)

17 Citations (Scopus)
1995

Carbenoids from Primary Alkyl Chlorides by Heteroatom-Assisted Metallation

Clayden, J. & Julia, M., 1 Jan 1995, In : SYNLETT. 1995, 01, p. 103-104 2 p.

Research output: Contribution to journalArticle (Academic Journal)

Diastereoisomeric atropisomers from the addition of lithiated N,N-dialkyl-l-naphthamides to aldehydes

Bowles, P., Clayden, J. & Tomkinson, M., 11 Dec 1995, In : Tetrahedron Letters. 36, 50, p. 9219-9222 4 p.

Research output: Contribution to journalArticle (Academic Journal)

44 Citations (Scopus)
48 Citations (Scopus)
1996

Asymmetric induction using atropisomers: Diastereoselective additions to 2-acyl-1-naphthamides

Clayden, J., Westlund, N. & Wilson, F. X., 29 Jul 1996, In : Tetrahedron Letters. 37, 31, p. 5577-5580 4 p.

Research output: Contribution to journalArticle (Academic Journal)

51 Citations (Scopus)

Stereocontrol

Clayden, J. & Warren, S., 16 Feb 1996, In : Angewandte Chemie - International Edition. 35, 3, p. 241-270 30 p.

Research output: Contribution to journalArticle (Academic Journal)

161 Citations (Scopus)
1997

Atroposelectivity in the reactions of laterally lithiated tertiary amides

Clayden, J. & Pink, J. H., 7 Apr 1997, In : Tetrahedron Letters. 38, 14, p. 2561-2564 4 p.

Research output: Contribution to journalArticle (Academic Journal)

42 Citations (Scopus)

Atroposelectivity in the reactions of ortholithiated aromatic tertiary amides with aldehydes

Bowles, P., Clayden, J., Helliwell, M., McCarthy, C., Tomkinson, M. & Westlund, N., 7 Sep 1997, In : Journal of the Chemical Society, Perkin Transactions 1. 17, p. 2607-2616 10 p.

Research output: Contribution to journalArticle (Academic Journal)

81 Citations (Scopus)

Configurational stability and stereospecificity in the reactions of amide-stabilised organolithiums: A non-stereospecific tin-lithium exchange

Clayden, J. & Pink, J. H., 7 Apr 1997, In : Tetrahedron Letters. 38, 14, p. 2565-2568 4 p.

Research output: Contribution to journalArticle (Academic Journal)

44 Citations (Scopus)

Diastereoselective reactions of optically active γ-substituted vinyl phosphine oxides

Clayden, J., Nelson, A. & Warren, S., 12 May 1997, In : Tetrahedron Letters. 38, 19, p. 3471-3474 4 p.

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)

Non-biaryl atropisomers: New classes of chiral reagents, auxiliaries, and ligands?

Clayden, J., 16 May 1997, In : Angewandte Chemie - International Edition. 36, 9, p. 949-951 3 p.

Research output: Contribution to journalArticle (Academic Journal)

145 Citations (Scopus)

Remote stereocontrol using rotationally restricted amides: (1,5)-Asymmetric induction

Clayden, J., Darbyshire, M., Pink, J. H., Westlund, N. & Wilson, F. X., 8 Dec 1997, In : Tetrahedron Letters. 38, 49, p. 8587-8590 4 p.

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)
1998

(S)-2-(Dibenzylamino)-3-phenylpropanal as a chiral auxiliary: A new strategy for the asymmetric synthesis of 2-substituted alcohols

Clayden, J., McCarthy, C. & Cumming, J. G., 24 Apr 1998, In : Tetrahedron: Asymmetry. 9, 8, p. 1427-1440 14 p.

Research output: Contribution to journalArticle (Academic Journal)

21 Citations (Scopus)

Anionic cyclisations of an N-benzyl naphthamide: A route to benzo[e]isoindolones

Ahmed, A., Clayden, J. & Rowley, M., 7 Feb 1998, In : Chemical Communications. 3, p. 297-298 2 p.

Research output: Contribution to journalArticle (Academic Journal)

65 Citations (Scopus)

Anion translocation in organolithiums: A mechanism for the lithiation and cyclisation of tertiary naphthamides

Ahmed, A., Clayden, J. & Rowley, M., 20 Aug 1998, In : Tetrahedron Letters. 39, 34, p. 6103-6106 4 p.

Research output: Contribution to journalArticle (Academic Journal)

52 Citations (Scopus)

Barriers to rotation about the chiral axis of tertiary aromatic amides

Ahmed, A., Bragg, R. A., Clayden, J., Lai, L. W., McCarthy, C., Pink, J. H., Westlund, N. & Yasin, S. A., 22 Oct 1998, In : Tetrahedron. 54, 43, p. 13277-13294 18 p.

Research output: Contribution to journalArticle (Academic Journal)

171 Citations (Scopus)

Concerted rotation in a tertiary aromatic amide: Towards a simple molecular gear

Clayden, J. & Pink, J. H., 3 Aug 1998, In : Angewandte Chemie - International Edition. 37, 13-14, p. 1937-1939 3 p.

Research output: Contribution to journalArticle (Academic Journal)

98 Citations (Scopus)

Conformationally interlocked amides: Remote asymmetric induction by mechanical transfer of stereochemical information

Clayden, J., Pink, J. H. & Yasin, S. A., 1 Jan 1998, In : Tetrahedron Letters. 39, 1-2, p. 105-108 4 p.

Research output: Contribution to journalArticle (Academic Journal)

64 Citations (Scopus)

Controlling the regioselectivity of lithiation using kinetic isotope effects: Deuterium as a protecting group for carbon

Clayden, J., Pink, J. H., Westlund, N. & Wilson, F. X., 12 Nov 1998, In : Tetrahedron Letters. 39, 46, p. 8377-8380 4 p.

Research output: Contribution to journalArticle (Academic Journal)

43 Citations (Scopus)
5 Citations (Scopus)

Stereocontrol with rotationally restricted amides

Clayden, J., Aug 1998, In : SYNLETT. 8, p. 810-816 7 p.

Research output: Contribution to journalArticle (Academic Journal)

92 Citations (Scopus)
1999

1,3,4,5-Tetrahydroazepin-2-ones by dearomatising anionic cyclisation of N-allyl-1-naphthamides

Ahmed, A., Clayden, J. & Rowley, M., 1999, In : SYNLETT. 12, p. 1954-1956 3 p.

Research output: Contribution to journalArticle (Academic Journal)

28 Citations (Scopus)

Bonded peri-interactions govern the rate of racemisation of atropisomeric 8-substituted 1-naphthamides

Clayden, J., McCarthy, C. & Helliwell, M., 21 Oct 1999, In : Chemical Communications. 20, p. 2059-2060 2 p.

Research output: Contribution to journalArticle (Academic Journal)

51 Citations (Scopus)

Dearomatising cyclisations of lithiated N-benzylbenzamides

Ahmed, A., Clayden, J. & Yasin, S. A., 7 Feb 1999, In : Chemical Communications. 3, p. 231-232 2 p.

Research output: Contribution to journalArticle (Academic Journal)

51 Citations (Scopus)

Diastereoisomeric atropisomers of peri-substituted naphthamides: Synthesis, stereoselectivity and stability

Clayden, J., Westlund, N. & Wilson, F. X., 5 Nov 1999, In : Tetrahedron Letters. 40, 45, p. 7883-7887 5 p.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

Diastereoselective ortholithiation and conformational control in stereospecific dearomatising anionic cyclisations

Bragg, R. A. & Clayden, J., 26 Nov 1999, In : Tetrahedron Letters. 40, 48, p. 8327-8331 5 p.

Research output: Contribution to journalArticle (Academic Journal)

26 Citations (Scopus)
87 Citations (Scopus)

Perilithiation and the synthesis of 8-substituted-1-naphthamides

Clayden, J., Frampton, C. S., McCarthy, C. & Westlund, N., 3 Dec 1999, In : Tetrahedron. 55, 49, p. 14161-14184 24 p.

Research output: Contribution to journalArticle (Academic Journal)

50 Citations (Scopus)

Stereospecific formation of tetrasubstituted centres from trisubstituted centres during dearomatising anionic cyclisations

Bragg, R. A. & Clayden, J., 26 Nov 1999, In : Tetrahedron Letters. 40, 48, p. 8323-8326 4 p.

Research output: Contribution to journalArticle (Academic Journal)

34 Citations (Scopus)

Synthesis of atropisomeric 2-(1-aminoalkyl)-1-naphthamides by stereoselective addition of organolithiums to a 2-imino-1-naphthamide

Clayden, J., Westlund, N. & Wilson, F. X., 23 Apr 1999, In : Tetrahedron Letters. 40, 17, p. 3329-3330 2 p.

Research output: Contribution to journalArticle (Academic Journal)

21 Citations (Scopus)

Synthesis of atropisomeric diamides with remotely related stereogenic axes by stereoselective additions to imines

Clayden, J., Westlund, N. & Wilson, F. X., 23 Apr 1999, In : Tetrahedron Letters. 40, 17, p. 3331-3334 4 p.

Research output: Contribution to journalArticle (Academic Journal)

26 Citations (Scopus)
2000

Atropisomeric amides as chiral, ligands: Using (-)-sparteine-directed enantioselective silylation to control the conformation of a stereogenic axis

Clayden, J., Johnson, P., Pink, J. H. & Helliwell, M., 20 Oct 2000, In : Journal of Organic Chemistry. 65, 21, p. 7033-7040 8 p.

Research output: Contribution to journalArticle (Academic Journal)

125 Citations (Scopus)