Personal profile

Research interests

My research focuses on the structure-function relationships in voltage-gated potassium channels. In particular, I examine the effects of arrhythmia-associated genetic variants on the biophysics of delayed rectifying currents in the human heart.

I use a variety of techniques, including patch-clamp electrophysiology, mutagenesis and biochemical methods to interrogate these mutations and determine their functional consequences.

I am also interested in the intracellular trafficking and membrane recycling of ion channels and how this relates to disease.

Research Groups and Themes

  • Bristol Heart Institute

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