Professor Julian F R Paton

B.Sc.(Birm.), Ph.D.(Lond.)

  • BS8 1TD

19992020

Research output per year

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Research Output

2020

Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow

Marina, N., Christie, I. N., Korsak, A., Doronin, M., Brazhe, A., Hosford, P. S., Wells, J. A., Sheikhbahaei, S., Humoud, I., Paton, J. F. R., Lythgoe, M. F., Semyanov, A., Kasparov, S. & Gourine, A. V., 9 Jan 2020, In : Nature Communications. 11, 1, 9 p., 131 (2020).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
65 Downloads (Pure)

Efficacy of Electrical Baroreflex Activation Is Independent of Peripheral Chemoreceptor Modulation

Heusser, K., Thöne, A., Lipp, A., Menne, J., Beige, J., Reuter, H., Hoffmann, F., Halbach, M., Eckert, S., Wallbach, M., Koziolek, M., Haarmann, H., Joyner, M. J., Paton, J. F. R., Diedrich, A., Haller, H., Jordan, J. & Tank, J., 1 Jan 2020, In : Hypertension. 75, 1, p. 257-264 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Enhancing respiratory sinus arrhythmia increases cardiac output in rats with left ventricular dysfunction

O'Callaghan, E. L., Lataro, R. M., Roloff, E. L., Chauhan, A. S., Salgado, H. C., Duncan, E., Nogaret, A. & Paton, J. F. R., 1 Feb 2020, In : Journal of Physiology. 598, 3, p. 455-471 17 p.

Research output: Contribution to journalArticle (Academic Journal)

2 Citations (Scopus)

Increased apelin receptor gene expression in the subfornical organ of spontaneously hypertensive rats.

Griffiths, P. R., Lolait, S. J., Bijabhai, A., O'Carroll-Lolait, A., Paton, J. F. R. & O'Carroll, A-M., 21 Apr 2020, In : PLoS ONE.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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34 Downloads (Pure)
Open Access
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36 Downloads (Pure)

Retrograde Blood Flow in the Internal Jugular Veins of Humans With Hypertension May Have Implications for Cerebral Arterial Blood Flow

Rodrigues, J. C. L., Strelko, G., Warnert, E. A., Burchell, A. E., Neumann, S., Radcliffe, L., Harris, A. D., Chant, B. J., Bowles, R., Nightingale, A. K., Wise, R. G., Paton, J. F. R. & Hart, E. C. J., 10 Mar 2020, In : European Radiology.

Research output: Contribution to journalArticle (Academic Journal)

The antidotes atropine and pralidoxime distinctively recover cardiorespiratory components impaired by acute poisoning with chlorpyrifos in rats

Felippe, I. S. A., Müller, C. J. T., Siqueira, A. A., dos Santos, L., Cavadino, A., Paton, J. F. R., Beijamini, V. & Sampaio, K. N., 15 Jan 2020, In : Toxicology and Applied Pharmacology. 389, 11 p., 114879.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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44 Downloads (Pure)
2019

Centrally acting adrenomedullin in the long-term potentiation of sympathetic vasoconstrictor activity induced by intermittent hypoxia in rats

Zoccal, D. B., Colombari, D. S. A., Colombari, E., Flor, K. C., da Silva, M. P., Costa-Silva, J. H., Machado, B. H., Moraes, D. J. A., Murphy, D. & Paton, J. F. R., 1 Sep 2019, In : Experimental Physiology. 104, 9, p. 1371-1383 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
17 Downloads (Pure)

Cerebral Blood Flow Response to Simulated Hypovolemia in Essential Hypertension: A Magnetic Resonance Imaging Study

Neumann, S., Burchell, A. E., Rodrigues, J. C. L., Lawton, C. B., Burden, D., Underhill, M., Kobetić, M. D., Adams, Z. H., Brooks, J. C. W., Nightingale, A. K., Paton, J. F. R., Hamilton, M. C. K. & Hart, E. C., 1 Dec 2019, In : Hypertension. 74, 6, p. 1391-1398 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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89 Downloads (Pure)

Inflammatory pathways are central to posterior cerebrovascular artery remodelling prior to the onset of congenital hypertension

Walas, D., Nowicki-Osuch, K., Alibhai, D. R., von Linstow Roloff, E., Coghill, J. A., Waterfall, C. M. & Paton, J. F. R., 1 Sep 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, p. 1803-1817 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1 Citation (Scopus)
235 Downloads (Pure)

Intermittent Exposure to Chlorpyrifos Differentially Impacts Neuroreflex Control of Cardiorespiratory Function in Rats

Batista, T. J., Minassa, V. S., Aitken, A. V., Jara, B. T., Felippe, I. S. A., Beijamini, V., Paton, J. F. R., dos Santos, L. & Sampaio, K. N., 1 Dec 2019, In : Cardiovascular Toxicology. 19, 6, p. 548-564 17 p.

Research output: Contribution to journalArticle (Academic Journal)

On the presence and functional significance of sympathetic premotor neurons with collateralized spinal axons in the rat

Farmer, D. G. S., Pracejus, N., Dempsey, B., Turner, A., Bokiniec, P., Paton, J. F. R., Pickering, A. E., Burguet, J., Andrey, P., Goodchild, A. K., McAllen, R. M. & McMullan, S., 1 Jul 2019, In : Journal of Physiology. 597, 13, p. 3407-3423 17 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
13 Downloads (Pure)

Optimal solid state neurons

Abu-Hassan, K., Taylor, J. D., Morris, P. G., Donati, E., Bortolotto, Z. A., Indiveri, G., Paton, J. F. R. & Nogaret, A., 3 Dec 2019, In : Nature Communications. 10, 13 p., 5309 (2019).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1 Citation (Scopus)
102 Downloads (Pure)

Renal Denervation Update From the International Sympathetic Nervous System Summit: JACC State-of-the-Art Review

Kiuchi, M. G., Esler, M. D., Fink, G. D., Osborn, J. W., Banek, C. T., Böhm, M., Denton, K. M., DiBona, G. F., Everett, T. H., Grassi, G., Katholi, R. E., Knuepfer, M. M., Kopp, U. C., Lefer, D. J., Lohmeier, T. E., May, C. N., Mahfoud, F., Paton, J. F. R., Schmieder, R. E., Pellegrino, P. R. & 2 others, Sharabi, Y. & Schlaich, M. P., 18 Jun 2019, In : Journal of the American College of Cardiology. 73, 23, p. 3006-3017 27 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
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8 Citations (Scopus)
5 Downloads (Pure)

Repaired coarctation of the aorta, persistent arterial hypertension and the selfish brain

Rodrigues, J. C. L., Jaring, M. F. R., Werndle, M. C., Mitrousi, K., Lyen, S. M., Nightingale, A. K., Hamilton, M. C. K., Curtis, S. L., Manghat, N. E., Paton, J. F. R. & Hart, E. C., 7 Nov 2019, In : Journal of Cardiovascular Magnetic Resonance. 21, 10 p., 68 (2019) .

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1 Citation (Scopus)
87 Downloads (Pure)

Th17 responses to pneumococcus in blood and adenoidal cells in children

Oliver, E. H., Pope, C., Clarke, E., Langton Hewer, C., Ogunniyi, A. D., Paton, J. C., Mitchell, T., Malley, R. & Finn, A., Feb 2019, In : Clinical and Experimental Immunology. 195, 2, p. 213-225 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
102 Downloads (Pure)
2018

Antihypertensive Treatment Fails to Control Blood Pressure During Exercise

Chant, B., Bakali, M., Hinton, T., Burchell, A. E., Nightingale, A. K., Paton, J. F. R. & Hart, E. C., 1 Jul 2018, In : Hypertension. 72, 1, p. 102-109 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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11 Citations (Scopus)
264 Downloads (Pure)

Blockade of rostral ventrolateral medulla apelin receptors does not attenuate arterial pressure in SHR and L-NAME-induced hypertensive rats

Griffiths, P., Lolait, S., Pearce, L., McBryde, F., Paton, J. & O'Carroll, A-M., 24 Oct 2018, In : Frontiers in Physiology. 9, 16 p., 1488.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
178 Downloads (Pure)

Differences in autonomic innervation to the vertebrobasilar arteries in spontaneously hypertensive and Wistar rats

Roloff, E. V. L., Walas, D., Moraes, D. J. A., Kasparov, S. & Paton, J. F. R., 15 Aug 2018, In : Journal of Physiology. 596, 16, p. 3505-3529 25 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
120 Downloads (Pure)

Hypothalamic paraventricular nucleus neuronal nitric oxide synthase activity is a major determinant of renal sympathetic discharge in conscious Wistar rats

McBryde, F., Liu, B., Roloff, E., Kasparov, S. & Paton, J., 19 Jan 2018, In : Experimental Physiology. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
223 Downloads (Pure)

Left ventricular extracellular volume fraction and atrioventricular interaction in hypertension

Rodrigues, J. C. L., Erdei, T., Dastidar, A. G., Szantho, G., Burchell, A. E., Ratcliffe, L. E. K., Hart, E. C., Nightingale, A. K., Paton, J. F. R., Manghat, N. E. & Hamilton, M. C. K., 19 Sep 2018, In : European Radiology. 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1 Citation (Scopus)
169 Downloads (Pure)

Locus Coeruleus as a vigilance centre for active inspiration and expiration in rats

Magalhaes, K., Spiller, P., Da Silva, M. P., Kuntze, L., Paton, J., Machado, B. & Moraes, D. JA., 23 Oct 2018, In : Scientific Reports. 8, 1, 14 p., 15654.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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8 Citations (Scopus)
271 Downloads (Pure)

Neuroreflex control of cardiovascular function is impaired after acute poisoning with chlorpyrifos, an organophosphorus insecticide: Possible short and long term clinical implications

Cunha, A. F., Felippe, I. S. A., Ferreira-Junior, N. C., Resstel, L. B. M., Guimarães, D. A. M., Beijamini, V., Paton, J. F. R. & Sampaio, K. N., 1 Apr 2018, In : Toxiocology. 398-399, p. 13-22 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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5 Citations (Scopus)
212 Downloads (Pure)

Noctural dipping status and left ventricular hypertrophy: A cardiac magnetic resonance imaging study

Rodrigues, J. C. L., Amadu, A. M., Ghosh Dastidar, A., Harries, I., Burchell, A. E., Ratcliffe, L. E. K., Hart, E. C., Hamilton, M. C. K., Paton, J. F. R., Nightingale, A. K. & Manghat, N. E., Apr 2018, In : Journal of Clinical Hypertension. 20, 4, p. 784-793 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
196 Downloads (Pure)

The effects of aging on biosynthetic processes in the rat hypothalamic osmoregulatory neuroendocrine system

Greenwood, M. P., Greenwood, M., Romanova, E. V., Mecawi, A. S., Paterson, A., Sarenac, O., Japundžić-Žigon, N., Antunes-Rodrigues, J., Paton, J. F. R., Sweedler, J. V. & Murphy, D., 1 May 2018, In : Neurobiology of Aging. 65, p. 178-191 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
186 Downloads (Pure)

The Kölliker-Fuse orchestrates the timing of expiratory abdominal nerve bursting

Barnett, W. H., Jenkin, S. E. M., Milsom, W. K., Paton, J., Abdala, A. P., Molkov, Y. I. & Zoccal, D., Feb 2018, In : Journal of Neurophysiology. 119, 2, p. 401-412 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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14 Citations (Scopus)
228 Downloads (Pure)

Variable role of carotid bodies in cardiovascular responses to exercise, hypoxia and hypercapnia in spontaneously hypertensive rats

Pijacka, W., Katayama, P. L., Salgado, H. C., Lincevicius, G. S., Campos, R. R., McBryde, F. D. & Paton, J. F. R., 1 Aug 2018, In : Journal of Physiology. 596, 15, p. 3201-3216 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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8 Citations (Scopus)
224 Downloads (Pure)
2017

Cardiac magnetic resonance imaging provides a new insight in hypertensive heart disease – a reply

Rodrigues, J., Rohan, S., Ghosh Dastidar, A., Trickey, A., Szantho, G., Ratcliffe, L., Burchell, A., Hart, E., Bucciarelli-Ducci, C., Hamilton, M. C. K., Nightingale, A., Paton, J., Manghat, N. E. & Maclver, D., 7 Mar 2017, In : Journal of Clinical Hypertension. 19, 3, p. 335–336 2 p.

Research output: Contribution to journalLetter (Academic Journal)

Open Access
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138 Downloads (Pure)

Cardiovascular autonomic regulation, inflammation and pain in rheumatoid arthritis

Adlan, A. M., Veldhuijzen van Zanten, J. J. C. S., Lip, G. Y. H., Paton, J. F. R., Kitas, G. D. & Fisher, J. P., 13 Sep 2017, In : Autonomic Neuroscience: Basic and Clinical.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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7 Citations (Scopus)
212 Downloads (Pure)

Carotid body resection for sympathetic modulation in systolic heart failure – results from first-in-man study

Niewinski, P., Janczak, D., Rucinski, A., Tubek, S., Engelman, Z. J., Piesiak, P., Jazwiec, P., Banasiak, W., Fudim, M., Sobotka, P. A., Javaheri, S., Hart, E. C. J., Paton, J. F. R. & Ponikowski, P., Mar 2017, In : European Journal of Heart Failure. 19, 3, p. 391–400 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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41 Citations (Scopus)
297 Downloads (Pure)

Cerebral Aβ40 and systemic hypertension

Tayler, H. M., Palmer, J. C., Thomas, T. L., Kehoe, P. G., Paton, J. F. R. & Love, S., 7 Aug 2017, In : Journal of Cerebral Blood Flow and Metabolism. 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
284 Downloads (Pure)

Chemoreception and neuroplasticity in respiratory circuits

Barnett, W. H., Abdala, A. P., Paton, J. F. R., Rybak, I. A., Zoccal, D. B. & Molkov, Y. I., Jan 2017, In : Experimental Neurology. 287 Part 2, p. 153-164 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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27 Citations (Scopus)
260 Downloads (Pure)

Comprehensive First-Line Magnetic Resonance Imaging in Hypertension: Experience From a Single-Center Tertiary Referral Clinic

Burchell, A. E., Rodrigues, J. C. L., Charalambos, M., Ratcliffe, L. E. K., Hart, E. C., Paton, J. F. R., Baumbach, A., Manghat, N. E. & Nightingale, A. K., Jan 2017, In : Journal of Clinical Hypertension. 19, 1, p. 13–22 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
235 Downloads (Pure)

Cooperative Oxygen Sensing by the Kidney and Carotid Body in Blood Pressure Control

Patinha, D., Pijacka, W., Paton, J. & Koeners, M., 4 Oct 2017, In : Frontiers in Physiology. 8, 13 p., 752.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
252 Downloads (Pure)

Descending systems direct development of key spinal motor circuits

Smith, C. C., Paton, J., Chakrabarty, S. & Ichiyama, R. M., 28 Jun 2017, In : Journal of Neuroscience. 37, 26, p. 6372-6387 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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14 Citations (Scopus)
269 Downloads (Pure)

ECG strain pattern in hypertension is associated with myocardial cellular expansion and diffuse interstitial fibrosis: a multi-parametric cardiac magnetic resonance study

Rodrigues, J. C. L., Amadu, A. M., Ghosh Dastidar, A., McIntyre, B., Szantho, G. V., Lyen, S., Godsave, C., Ratcliffe, L. E. K., Burchell, A. E., Hart, E. C., Hamilton, M. C. K., Nightingale, A. K., Paton, J. F. R., Manghat, N. E. & Bucciarelli-Ducci, C., Apr 2017, In : European Heart Journal - Cardiovascular Imaging. 18, 4, p. 441-450 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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14 Citations (Scopus)
214 Downloads (Pure)

Electrocardiographic detection of hypertensive left atrial enlargement in the presence of obesity: re-calibration against cardiac magnetic resonance

Rodrigues, J. C. L., Erdei, T., Ghosh Dastidar, A., McIntyre, B., Burchell, A. E., Ratcliffe, L. E. K., Hart, E. C. J., Hamilton, M. C. K., Paton, J. F. R., Nightingale, A. K. & Manghat, N. E., Mar 2017, In : Journal of Human Hypertension. 31, 3, p. 212–219 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
315 Downloads (Pure)

Evaluating the carotid bodies and renal nerves as therapeutic targets for hypertension

McBryde, F., Hart, E., Ramchandra, R. & Paton, J., 1 May 2017, In : Autonomic Neuroscience: Basic and Clinical. 204, p. 126-130 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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6 Citations (Scopus)
284 Downloads (Pure)

Hypertensive heart disease versus hypertrophic cardiomyopathy: multi-parametric cardiovascular magnetic resonance discriminators when end-diastolic wall thickness ≥ 15 mm

Rodrigues, J. C. L., Rohan, S., Ghosh Dastidar, A., Harries, I., Lawton, C. B., Ratcliffe, L. E., Burchell, A. E., Hart, E. C., Hamilton, M. C. K., Paton, J. F. R., Nightingale, A. K. & Manghat, N. E., Mar 2017, In : European Radiology. 27, 3, p. 1125-1135 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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13 Citations (Scopus)
360 Downloads (Pure)

Increased sympathetic nerve activity and reduced cardiac baroreflex sensitivity in rheumatoid arthritis

Adlan, A. M., Paton, J. F. R., Lip, G. Y. H., Kitas, G. D. & Fisher, J. P., 1 Feb 2017, In : Journal of Physiology. 595, 3, p. 967-981 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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18 Citations (Scopus)
228 Downloads (Pure)

Intracranial mechanisms for preserving brain blood flow in health and disease

McBryde, F. D., Malpas, S. C. & Paton, J., Jan 2017, In : Acta Psychologica. 219, 1, p. 274-287 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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24 Citations (Scopus)
323 Downloads (Pure)

Renal Denervation Reduces Pulmonary Vascular Remodeling and Right Ventricular Diastolic Stiffness in Experimental Pulmonary Hypertension

da Silva Gonçalves Bos, D., Happé, C., Schalij, I., Pijacka, W., Paton, J. F. R., Guignabert, C., Tu, L., Thuillet, R., Bogaard, H-J., van Rossum, A. C., Vonk-Noordegraaf, A., de Man, F. S. & Handoko, M. L., Feb 2017, In : JACC: Basic to Translational Science. 2, 1, p. 22–35 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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12 Citations (Scopus)
300 Downloads (Pure)

Role of ventral medullary catecholaminergic neurons for respiratory modulation of sympathetic outflow in rats

Moraes, D. J. A., Bonagamba, L. G. H., Da Silva, M. P., Paton, J. F. R. & Machado, B. H., 4 Dec 2017, In : Scientific Reports. 7, 16 p., 16883.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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6 Citations (Scopus)
208 Downloads (Pure)

The human ventilatory response to stress: rate or depth?

Tipton, M. J., Harper, A., Paton, J. F. R. & Costello, J. T., Sep 2017, In : Journal of Physiology. 595, 17, p. 5729-5752 24 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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33 Citations (Scopus)
234 Downloads (Pure)

Vasopressin V1a receptors mediate the hypertensive effects of [Pyr1]apelin-13 in the rat rostral ventrolateral medulla

Griffiths, P., Lolait, S., Harris, L., Paton, J. & O'Carroll, A-M., Jun 2017, In : Journal of Physiology. 595, 11, p. 3303-3318 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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9 Citations (Scopus)
250 Downloads (Pure)
2016

Appeasing the carotid body after chronic intermittent hypoxia

Paton, J. F. R., 1 Aug 2016, In : Hypertension. 68, 2, p. 315-317 3 p.

Research output: Contribution to journalEditorial (Academic Journal)

Open Access
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2 Citations (Scopus)
226 Downloads (Pure)

Autonomic and neuroendocrine dysfunction in chronic disease

Paton, J., Mar 2016, In : Journal of Physiology. 594, 6, p. 1579-1580 2 p.

Research output: Contribution to journalEditorial (Academic Journal)

Brainstem Sources of Cardiac Vagal Tone and Respiratory Sinus Arrhythmia

Farmer, D. G. S., Dutschmann, M., Paton, J., Pickering, A. E. & McAllen, R., 15 Dec 2016, In : Journal of Physiology. 594, 24, p. 7249-7265 17 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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31 Citations (Scopus)
308 Downloads (Pure)