Professor Julian P Hamilton-Shield

M.B.,Ch.B., M.D.(Bristol), M.R.C.P., FRCPCH

  • BS2 8AE

20002020

Research output per year

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Research Output

  • 125 Article (Academic Journal)
  • 9 Conference Contribution (Conference Proceeding)
  • 2 Letter (Academic Journal)
  • 2 Review article (Academic Journal)

3-Hydroxyisobutyrate aciduria and mutations in the ALDH6A1 gene coding for methylmalonate semialdehyde dehydrogenase

Sass, JO., Walter, M., Shield, JPH., Atherton, AM., Garg, U., Scott, D., Woods, CG. & Smith, LD., Aug 2011, In : Journal of Inherited Metabolic Disease.

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)

6q24 transient neonatal diabetes

Temple, IK. & Shield, JPH., Sep 2010, In : Reviews in Endocrine and Metabolic Disorders. 11(3), p. 199 - 204 6 p.

Research output: Contribution to journalArticle (Academic Journal)

46 Citations (Scopus)

Abnormal liver function in children with metabolic syndrome from a UK-based obesity clinic

Wei, C., Ford, A., Hunt, LP., Crowne, E. & Shield, JPH., Nov 2010, In : Archives of Disease in Childhood. 96(11), p. 1003 - 1007 4 p.

Research output: Contribution to journalArticle (Academic Journal)

19 Citations (Scopus)

Activating Mutations in the Gene Encoding the ATP-Sensitive Potassium-Channel Subunit Kir6.2 and Permanent Neonatal Diabetes

Gloyn, AL., Pearson, ER., Antcliff, JF., Proks, P., Bruining, GJ., Slingerland, AS., Howard, N., Srinivasan, S., Silva, JMCL., Molnes, J., Edghill, EL., Frayling, TM., Temple, IK., Mackay, D., Shield, JPH., Sumnik, Z., van Rhijn, A., Wales, JKH., Clark, P., Gorman, S. & 5 others, Aisenberg, J., Ellard, S., Njølstad, PR., Ashcroft, FM. & Hattersley, AT., 29 Apr 2004, In : New England Journal of Medicine. 350 (18), p. 1838 - 1849 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Adipogenesis and IGF-I

Holly, JMP., Sabin, M., Perks, CM. & Shield, JPH., Mar 2006, In : Metabolic Syndrome and Related Disorders. 4 (1), p. 43 - 50 8 p.

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)

Adolescent experiences of anti-obesity drugs

White, B., Jamieson, L., Clifford, S., Hamilton-Shield, J. P., Christie, D., Smith, F., Wong, I. C. K. & Viner, R. M., 20 May 2015, In : Clinical Obesity. 5, 3, p. 116-26 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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259 Downloads (Pure)

Adolescents’ views and experiences of treatments for Type 2 diabetes: a qualitative study.

Turner, K. M., Percival, J., Dunger, D., Olbers, T., Barrett, T. & Hamilton-Shield, J. P., 2014, In : Diabetic Medicine. p. Epub ahead of print 1 p., 25186101.

Research output: Contribution to journalArticle (Academic Journal)

5 Citations (Scopus)

Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT): urinary screening and baseline biochemical and cardiovascular assessments

Marcovecchio, M. L., Woodside, J., Jones, T., Daneman, D., Neil, A., Prevost, T., Dalton, R. N., Deanfield, J., Dunger, D. B., Acerini, C., Anand, B., Barrett, T., Birrell, V., Campbell, F., Ackland, F., Cheetham, T., Cooper, C., Doughty, I., Dutta, A., Edge, J. & 25 others, Shield, J. P. H., Heywood, J., Leech, N., Mann, N., Parker, R., Rayman, G., Robinson, J. M., Russell-Taylor, M., Sankar, V., Thalange, N., Wilson, M., Bergman, P., Rodda, C., Cameron, F., Cotterill, A., Couper, J., Davis, E., Donaghue, K., Craig, M., King, B., Verge, C., Mahmud, F., Clarson, C., Curtis, J. & Sochett, E., 2014, In : Diabetes Care. 37, 3, p. 805-13 9 p.

Research output: Contribution to journalArticle (Academic Journal)

43 Citations (Scopus)

A double heterozygote for familial hypercholesterolaemia and familial defective apolipoprotein B-100

Taylor, A., Bayly, G., Patel, K., Yarram, L., Williams, M., Hamilton-Shield, J., Humphries, S. E. & Norbury, G., Sep 2010, In : Annals of Clinical Biochemistry. 47, Pt 5, p. 487-90 4 p.

Research output: Contribution to journalArticle (Academic Journal)

12 Citations (Scopus)

A maternal hypomethylation syndrome presenting as transient neonatal diabetes mellitus

Mackay, DM., Boonen, SE., Clayton-Smith, J., Goodship, J., Hahnemann, JM., Kant, SG., Njolsted, P., Robin, NH., Robinson, DO., Siebert, R., Shield, JPH., White, HE. & Temple, IK., Sep 2006, In : Human Genetics. 120 (2), p. 262 - 269 8 p.

Research output: Contribution to journalArticle (Academic Journal)

126 Citations (Scopus)

A recurrent mitochondrial p.Trp22Arg NDUFB3 variant causes a distinctive facial appearance, short stature and a mild biochemical and clinical phenotype

Alston, C. L., Howard, C., Oláhová, M., Hardy, S. A., He, L., Murray, P. G., O'Sullivan, S., Doherty, G., Hamilton-Shield, J. P., Hargreaves, I. P., Monavari, A. A., Knerr, I., McCarthy, P. W., Morris, A. A. M., Thorburn, D. R., Prokisch, H., Clayton, P., McFarland, R., Hughes, J., Crushell, E. & 1 others, Taylor, R. W., Sep 2016, In : Journal of Medical Genetics. 53, 9, p. 634-641 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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11 Citations (Scopus)
237 Downloads (Pure)
Open Access
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215 Downloads (Pure)

A respiratory chain disorder presenting as developemental delay and hypoglycaemia with adrenal insufficiency

Sabin, MA., Crowne, EC., Heales, S., Hargreaves, IP., Land, J., Sharples, P. & Hamilton-Shield, JP., 2002, European Society of Paediatric Endocrinology. Vol. 58. p. 149 - 149 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

A Respiratory Chain Disorder Presenting as Developmental Delay and Hypoglycaemia with Adrenal Insufficiency

Sabin, MA., Crowne, EC., Heales, S., Hargreaves, IP., Land, J., Sharples, PM. & Hamilton-Shield, J. P., 2002, 41st Annual Meeting of the European Society for Paediatric Endocrinology. Vol. 58 (S2). p. 149 - 149 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Assessment of childhood obesity in secondary care: OSCA consensus statement. A review

Viner, RM., White, B., Barrett, T., Candy, DC., Gibson, P., Gregory, JW., Matyka, K., Ong, K., Roche, E., Rudolf, MC., Shaikh, G., Shield, JPH. & Wales, JK., Jun 2012, In : Archives of Disease in Childhood: Education and Practice Edition. 97(3), p. 98 - 105

Research output: Contribution to journalArticle (Academic Journal)

Associations between physical activity and asthma, eczema and obesity in children aged 12–16: an observational cohort study

Jago, R., Salway, R., Ness, A. R., Shield, J. P. H., Ridd, M. & Henderson, J., 20 Jan 2019, In : BMJ Open. 9, 1, 8 p., e024858.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1 Citation (Scopus)
203 Downloads (Pure)

A systematic review and meta-analysis estimating the population prevalence of comorbidities in children and adolescents aged 5 to 18 years

Sharma, V., Coleman, S., Nixon, J., Sharples, L., Hamilton-Shield, J., Rutter, H. & Bryant, M., 3 Sep 2019, In : Obesity Reviews. 20, 10, p. 1341-1349 9 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
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11 Citations (Scopus)
202 Downloads (Pure)

Attitudes to Exercise and Diabetes in Young People with Type 1 Diabetes Mellitus: A Qualitative Analysis

Ryninks, K., Sutton, E., Thomas, E., Jago, R., Hamilton-Shield, J. P. & Burren, C. P., 14 Oct 2015, In : PLoS ONE. 12 p.

Research output: Contribution to journalArticle (Academic Journal)

10 Citations (Scopus)

Barriers engaging families and GPs in childhood weight management strategies

Banks, J., Shield, JPH. & Sharp, D., Aug 2011, In : British Journal of General Practice. 61, p. 492 - 497 6 p.

Research output: Contribution to journalArticle (Academic Journal)

10 Citations (Scopus)
4 Citations (Scopus)

Body composition after allogeneic hematopoietic cell transplantation / total body irradiation in children and young people: a restricted systematic review

Lorenc, A., Shield, J. P. H., Perry, R. E., Stevens, M. & CTYA HSCT Adipose and Muscle late effects working group, 18 Jul 2020, In : Journal of Cancer Survivorship. 19 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Downloads (Pure)

Bone marrow transplantation correcting beta-galactosidase activity does not influence neurological outcome in juvenile GM1-gangliosidosis

Hamilton-Shield, JP., Stone, J. & Steward, CG., 2005, In : Journal of Inherited Metabolic Disease. 28, p. 797 - 798 2 p.

Research output: Contribution to journalArticle (Academic Journal)

Can foster care ever be justified for weight management?

Williams, GM., Bredow, M. T., Barton, J., Pryce, R. & Hamilton-Shield, J. P., 2013, In : Archives of Disease in Childhood.

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)

Cardiovascular risk factors in obese children and their association with insulin resistance

Sabin, M. A., Crowne, EC. & Hamilton-Shield, JP., 2003, 22nd Joint Meeting of the British Endocrine Societies. Vol. 5. p. 92 - 92 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Challenges in delivering a cooking-from-scratch community programme for childhood obesity

Lorenc, A., Cooke, H., McCarthy, H., Birch, L., Hamilton-Shield, J. & Thompson, E., Sep 2017, In : Archives of Disease in Childhood. 102, 9, p. 877-878 2 p.

Research output: Contribution to journalLetter (Academic Journal)

Open Access
File
242 Downloads (Pure)

Changing eating behaviours to treat childhood obesity in the community using Mandolean: The Community Mandolean randomised controlled trial (ComMando) - A pilot study

Hamilton-Shield, J., Goodred, J., Powell, L. A., Thorn, J., Banks, J. P., Hollinghurst, S., Montgomery, A., Turner, K. & Sharp, D., Jul 2014, In : Health Technology Assessment. 18, 47, p. 1-75 75 p.

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)

Characterisation of a physiologically relevant model to investigate the differentiation of children's subcutaneous and visceral adipose tissue and the influences of TNFalpha and IGF-I

Grohmann, M., Holly, JMP., Hamilton-Shield, J. P., Crowne, E. & Stewart, CE., 2004, In : Journal of Lipid Research. 46, p. 93 - 103 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Characterisation of morbidity in a UK, hospital-based, obesity clinic

Sabin, M., Ford, AL., Holly, J. M. P., Hunt, L., Crowne, E. & Shield, JPH., 2006, In : Archives of Disease in Childhood. 91, 2, p. 126 - 130 5 p.

Research output: Contribution to journalArticle (Academic Journal)

36 Citations (Scopus)

Characteristics of children who do not attend their hospital appointments, and GPs’ response: a mixed methods study in primary and secondary care

French, L., Shield, J. P. H., Turner, K., Goldsworthy, L., Morley, H. & Sharp, D., Jul 2017, In : British Journal of General Practice. 67, 660, p. 483-489 7 p.

Research output: Contribution to journalArticle (Academic Journal)

5 Citations (Scopus)

Childhood obesity and type II diabetes

Sabin, MA., Crowne, EC. & Hamilton-Shield, J. P., 2002, In : Nursing Times. 98, p. 49 - 50 19.

Research output: Contribution to journalArticle (Academic Journal)

Children eat their school lunch too quickly: an exploratory study of the effect on food intake

Zandian, M., Ioakimidis, I., Bergstrom, J., Brodin, U., Bergh, C., Leon, M., Hamilton-Shield, J. P. & Sodersten, P., 14 May 2012, In : BMC Public Health. 12, 8 p., 351.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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18 Citations (Scopus)
203 Downloads (Pure)
16 Citations (Scopus)

Clinical and Molecular Characterisation of 300 patients with Congenital Hyperinsulinism

Kapoor, R. R., Flanagan, S. E., Arya, V. B., Hamilton-Shield, J. P., Ellard, S. & Hussain, K., 2013, In : European Journal of Endocrinology.

Research output: Contribution to journalArticle (Academic Journal)

106 Citations (Scopus)

Clinical and Molecular Characterisation Of Hyperinsulinaemic Hypoglycaemia In Infants Born Small-For-Gestational Age

Arya, V. B., Flanagan, S. E., Kumaran, A., Hamilton-Shield, J. P., Ellard, S., Hussain, K. & Kapoor, R. R., Jul 2013, In : Archives of Disease in Childhood: Fetal and Neonatal Edition. 98, 4, p. F356-F359 4 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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24 Citations (Scopus)
311 Downloads (Pure)

Clinical heterogeneity in patients with FOXP3 mutations presenting with permanent neonatal diabetes

Rubio-Cabezas, O., Minton, JA., Caswell, R., Shield, JPH., Deiss, D., Sumnik, Z., Cayssials, A., Herr, M., Loew, A., Lewis, V., Ellard, S. & Hattersley, AT., Jan 2009, In : Diabetes Care. 32(1), p. 111 - 116 6 p.

Research output: Contribution to journalArticle (Academic Journal)

77 Citations (Scopus)

Clinical measures of adiposity and percentage fat loss: which measure most accurately reflects fat loss and what should we aim for?

Hunt, LP., Ford, AL., Sabin, M., Crowne, E. & Shield, JPH., 2007, In : Archives of Disease in Childhood. 92, p. 399 - 403 4 p.

Research output: Contribution to journalArticle (Academic Journal)

45 Citations (Scopus)

Clinical presentation of 6q24 transient neonatal diabetes mellitus (6q24 TNDM) and genotype-phenotype correlation in an international cohort of patients

Louise E, D., S, K., A, L., E, H., L, H., SE, F., S, E. (ed.), AT, H., Hamilton-Shield, J. P., S, E., DJ, M. & IK, T., Apr 2013, In : Diabetologia. 56, 4, p. 758–762 5 p.

Research output: Contribution to journalArticle (Academic Journal)

67 Citations (Scopus)

Cognitive behavioural therapy stabilises glycaemic control in adolescents with type 1 diabetes-Outcomes from a randomised control trial

Wei, C., Allen, R. J., Tallis, P. M., Ryan, F. J., Hunt, L. P., Shield, J. P. H. & Crowne, E. C., 17 Apr 2017, In : Pediatric Diabetes.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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5 Citations (Scopus)
326 Downloads (Pure)

Commentary: The safety of early enteral feeding in children with acute pancreatitis

Shield, J. P. H. & Cusick, E. L., 12 Aug 2020, In : Pediatrics. e2020007211.

Research output: Contribution to journalArticle (Academic Journal)

Continuing rise of Type 2 diabetes incidence in children and young people in the UK

Candler, T. P., Mahmoud, O., Lynn, R. M., Majbar, A. A., Barrett, T. G. & Shield, J. P. H., 1 Jun 2018, In : Diabetic Medicine. 35, 6, p. 737-744 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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22 Citations (Scopus)
191 Downloads (Pure)

Control of Body Weight by Eating Behavior in Children

Zandian, M., Bergh, C., Ioakimidis, I., Esfandiari, M., Shield, J., Lightman, S., Leon, M. & Södersten, P., 19 Oct 2015, In : Frontiers in Pediatrics. 3, 6 p., 89.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
271 Downloads (Pure)

Cost and effectiveness of treatment options for childhood obesity

Hollinghurst, S. P., Hunt, L. P., Banks, J. P., Sharp, D. J. & Hamilton-Shield, J. P., 2013, In : International Journal of Pediatric Obesity.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

Deliberate sulphonylurea poisoning mimicking hyperinsulinaemia of infancy

Owen, L., Hamilton-Shield, J. P. & Ellis, M. E., May 2000, In : Archives of Disease in Childhood. 82, 5, p. 392-393 2 p.

Research output: Contribution to journalArticle (Academic Journal)

18 Citations (Scopus)

Depot-specific effects of fatty acids on lipid accumulation in children's adipocytes

Sabin, M., Crowne, E., Stewart, CEH., Hunt, LP., Welsh, G., Turner, SJ., Grohmann, M., Holly, JMP. & Shield, JP., Jul 2007, In : Biochemical and Biophysical Research Communications. 361 (2), p. 356 - 361 6 p.

Research output: Contribution to journalArticle (Academic Journal)

12 Citations (Scopus)

Diazoxide-responsive hyperinsulinemic hypoglycemia caused by HNF4A gene mutations

Flanagan, SE., Kapoor, RR., Mali, G., Cody, D., Murphy, N., Schwahn, B., Sianhanidou, T., Banerjee, I., Akcay, T., Rubio-Cabezas, O., Shield, JPH., Hussain, K. & Ellard, S., May 2010, In : European Journal of Endocrinology. 162(5), p. 987 - 992 6 p.

Research output: Contribution to journalArticle (Academic Journal)

82 Citations (Scopus)

Dietary interventions for managing glucose abnormalities in cystic fibrosis: a systematic review protocol

Birch, L., Lithander, F. E., Hewer, S. L., Harriman, K., Hamilton-Shield, J. & Perry, R., 18 Jul 2018, In : Systematic Reviews. 7, 6 p., 98.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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6 Citations (Scopus)
254 Downloads (Pure)

Early-Onset, Coexisting Autoimmunity and Decreased HLA-Mediated Susceptibility Are the Characteristics of Diabetes in Down Syndrome

Aitken, R. J., Mehers, K. L., Williams, A. J. K., Brown, J. L., Bingley, P. J., Holl, R. W., Rohrer, T. P., Schober, E., Abdul-Rasoul, M. M., Hamilton-Shield, J. P. & Gillespie, K. M., May 2013, In : Diabetes Care. 36, 5, p. 1181-1185 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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16 Citations (Scopus)
248 Downloads (Pure)

European Medicines Agency withdrawal for sibutramine

Galhardo, J., Davis, N., Matthai, S. & Shield, JPH., Oct 2010, In : Archives of Disease in Childhood. 95(10), p. 856 - 856 1 p.

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)