Professor Julian P Hamilton-Shield

M.B.,Ch.B., M.D.(Bristol), M.R.C.P., FRCPCH

  • BS2 8AE

20002020

Research output per year

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Research Output

  • 125 Article (Academic Journal)
  • 9 Conference Contribution (Conference Proceeding)
  • 2 Letter (Academic Journal)
  • 2 Review article (Academic Journal)
Article (Academic Journal)

Gut microbiome analysis by post: Evaluation of the optimal method to collect stool samples from infants within a national cohort study

Williams, G. M., Leary, S. D., Ajami, N. J., Chipper Keating, S., Petrosin, J. F., Hamilton-Shield, J. P. & Gillespie, K. M., 12 Jun 2019, In : PLoS ONE. 14, 6, 11 p., e0216557.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
153 Downloads (Pure)

High birth weight in a suburban hospital in Cameroon: An analysis of the clinical cut-off, prevalence, predictors and adverse outcomes

Choukem, S. P., Njim, T., Atashili, J., Hamilton-Shield, J. P. & Mbu, R., 29 Jun 2016, In : BMJ Open. 6, 6, 7 p., 011517.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
9 Citations (Scopus)
219 Downloads (Pure)

High intensity interval running enhances measures of physical fitness but not metabolic measures of cardiovascular disease risk in healthy adolescents

Buchan, DS., Ollis, S., Young, JD., Cooper, SM., Hamilton-Shield, J. P. & Baker, JS., 24 May 2013, In : BMC Public Health. 13, 12 p., 498.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
33 Citations (Scopus)
259 Downloads (Pure)

How does physical activity and fitness influence glycaemic control in young people with type 1 diabetes?

Cuenca-García, M., Jago, R., Hamilton-Shield, J. P. & Burren, C. P., Oct 2012, In : Diabetic Medicine. 29, 10, p. 369-376

Research output: Contribution to journalArticle (Academic Journal)

26 Citations (Scopus)
Open Access
File
3 Citations (Scopus)
214 Downloads (Pure)

Hypercholesterolaemia in children guidelines review

Baumer, JH. & Shield, JPH., Jun 2009, In : Archives of Disease in Childhood: Education and Practice Edition. 94(3), p. 84 - 86 3 p.

Research output: Contribution to journalArticle (Academic Journal)

5 Citations (Scopus)

Hypercholesterolaemia screening in Type 1 Diabetes: a difference of opinion

Candler, T., Mahmoud, O., Edge, J. & Hamilton-Shield, J., Jul 2017, In : Diabetic Medicine. 34, 7, p. 983-986 4 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
213 Downloads (Pure)

Hyperglycaemia confers resistance to chemotherapy on breast cancer cells: the role of fatty acid synthase

Zeng, L., Biernacka, K., Holly, JMP., Jarrett, CE., Morrison, A., Morgan, A., Winters, ZE., Foulstone, EJ., Hamilton-Shield, J. P. & Perks, CM., 1 Jun 2010, In : Endocrine-Related Cancer. 17, 2, p. 539 - 551 13 p.

Research output: Contribution to journalArticle (Academic Journal)

81 Citations (Scopus)

Hyperglycaemia-induced chemo-resistance in breast cancer cells: role of the estrogen receptor

Zeng, L., Zielinska, H. A., Arshad, A., Hamilton-Shield, J. P., Bahl, A., Holly, J. M. P. & Perks, C. M., 1 Feb 2016, In : Endocrine-Related Cancer. 23, 2, p. 125-134 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
11 Citations (Scopus)
222 Downloads (Pure)

Hyperinsulinaemic hypoglycaemia and diabetes mellitus due to dominant ABCC8/KCNJ11 mutations

Kapoor, RR., Flanagan, SE., James, CT., McKiernan, J., Thomas, AM., Harmer, SC., Hamilton-Shield, J. P., Tinker, A., Ellard, S. & Hussain, K., Oct 2011, In : Diabetologia. 54, 10, p. 2575-2583 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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36 Citations (Scopus)
242 Downloads (Pure)

Hyperinsulinism-hyperammonaemia syndrome: novel mutations in the GLUD1 gene and genotype-phenotype correlations

Kapoor, RR., Flanagan, SE., Fulton, P., Chakrapani, A., Chadefaux, B., Ben-Omran, T., Banerjee, I., Shield, JPH., Ellard, S. & Hussain, K., Nov 2009, In : European Journal of Endocrinology. 161(5), p. 731 - 735 5 p.

Research output: Contribution to journalArticle (Academic Journal)

64 Citations (Scopus)
19 Citations (Scopus)

Incidence and Clinical Associations of Childhood Acute Pancreatitis

Majbar, A., Cusick, E., Johnson, P., Lynn, R., Hunt, L. & Hamilton-Shield, J., 17 Aug 2016, In : Pediatrics. 138, 3, 9 p., e 20161198.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
12 Citations (Scopus)
254 Downloads (Pure)

Insulin and BMI as predictors of adult type 2 diabetes mellitus

Sabin, M. A., Magnussen, C. G., Juonala, M., Hamilton-Shield, J. P., Kähönen, M., Lehtimäki, T., Rönnemaa, T., Koskinen, J., Loo, B. M., Knip, M., Hutri-Kähönen, N., Viikari, J. S. A., Dwyer, T. & Raitakari, O. T., 1 Jan 2015, In : Pediatrics. 135, 1, p. e144-e151

Research output: Contribution to journalArticle (Academic Journal)

26 Citations (Scopus)

Insulin-like Growth Factor II (IGF-II) in Adipocyte Regulation: Depot-Specific Actions Suggest a Potential Role Limiting Excess Visceral Adiposity

Alfares, M. N., Perks, C. M., Hamilton-Shield, J. P. & Holly, J. M. P., 1 Dec 2018, In : AJP - Endocrinology and Metabolism. 315, 6, p. E1098-E1107 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
96 Downloads (Pure)

Interval Outcomes of a Lifestyle Weight-Loss Intervention in Early Adolescence

Wei, C., Candler, T., Crowne, E. & Hamilton-Shield, J. P., Jun 2018, In : Children. 5, 6, 6 p., 77.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
207 Downloads (Pure)

Is Child Abuse Associated with Adolescent Obesity? A Population Cohort Study

Hawton, K., Norris, T., Crawley, E. & Shield, J. P. H., Feb 2018, In : Childhood Obesity. 14, 2, p. 106-113 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
261 Downloads (Pure)

Is healthy eating for obese children necessarily more costly for families?

Banks, J. P., Williams, J., Cumberlidge, T., Cimonetti, T., Sharp, D. J. & Shield, JPH., Jan 2012, In : British Journal of General Practice. 62(594), p. e1 - e5

Research output: Contribution to journalArticle (Academic Journal)

15 Citations (Scopus)

Islet autoimmunity in children with Down's syndrome

Gillespie, KM., Dix, RJ., Williams, AJK., Newton, RW., Robinson, ZF., Bingley, PJ., Gale, EAM. & Shield, JPH., Nov 2006, In : Diabetes. 55 (11), p. 3185 - 3188 4 p.

Research output: Contribution to journalArticle (Academic Journal)

37 Citations (Scopus)

Isolation and validation of human prepubertal skeletal muscle cells: maturation and metabolic effects of IGF-I, IGFBP-3 and TNFalpha

Grohmann, M., Foulstone, E. J., Welsh, G., Holly, JMP., Hamilton-Shield, J. P., Crowne, E. & Stewart, CE., Oct 2005, In : Journal of Physiology. 568 , 1, p. 229 - 242 14 p.

Research output: Contribution to journalArticle (Academic Journal)

18 Citations (Scopus)

Is the childhood obesity crisis over in England?

Hamilton-Shield, J. & Sharp, D., Mar 2015, In : Archives of Disease in Childhood. 100, 3, p. 212-3 2 p.

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)

KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation

Pearce, LR., Atanassova, N., Banton, MC., Bottomley, B., van der Klaauw, AA., Revelli, JP., Hendricks, A., Keogh, JM., Henning, E., Doree, D., Jeter-Jones, S., Gang, S., Bochukova, EG., Bounds, R., Ashford, S., Gayton, E., Hindmarsh, PC., Hamilton-Shield, J. P., Crowne, E. C., Barford, D. & 7 others, Wareham, NJ., consortium, UKK., O'Rahilly, S., Murphy, MP., Powell, DR., Barroso, I. & Farooqi, IS., 2013, In : Cell. S0092-8674, (13)

Research output: Contribution to journalArticle (Academic Journal)

92 Citations (Scopus)

Large rare chromosomal deletions associated with severe early onset obesity

Ismaa, F., Elena Bochukova, N. V., Julia Keogh, N. V., Elana Henning, N. V., Carolin Purmann, N. V., Ni Huang, N. V., Kasia Blaszczyk, N. V., Sadia Saeed, N. V., Shield, JPH., Jill Clayton-Smith, N. V., Stephen O'Rahilly, N. V. & Matthew, H., 4 Feb 2010, In : Nature. 463, p. 666-670

Research output: Contribution to journalArticle (Academic Journal)

366 Citations (Scopus)

Longitudinal changes in body mass index following renal transplantation in UK children

Plumb, L., Pitcher, D., Tse, Y., Hamilton-Shield, J. P., Inward, C. & Sinha, MD., 2013, In : Nephrology Dialysis Transplantation.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A gene

Pearson, E., Boj, SF., Steele, AM., Barrett, TG., Stals, K., Shield, JPH., Ellard, SE., Ferrer, J. & Hattersley, AT., Apr 2007, In : PLoS Medicine. 4 (4) e118, p. 0760 - 0769 10 p.

Research output: Contribution to journalArticle (Academic Journal)

265 Citations (Scopus)

Management and one year outcome for UK children with type 2 diabetes

Shield, JPH., 2009, In : Archives of Disease in Childhood. 94, p. 206 - 209

Research output: Contribution to journalArticle (Academic Journal)

Maternal variants in NLRP and other maternal effect proteins are associated with multilocus imprinting disturbance in offspring

Begemann, M., Rezwan, F. I., Beygo, J., Docherty, L. E., Kolarova, J., Schroeder, C., Buiting, K., Chokkalingam, K., Degenhardt, F., Wakeling, E. L., Kleinle, S., González Fassrainer, D., Oehl-Jaschkowitz, B., Turner, C. L. S., Patalan, M., Gizewska, M., Binder, G., Bich Ngoc, C. T., Chi Dung, V., Mehta, S. G. & 10 others, Baynam, G., Hamilton-Shield, J. P., Aljareh, S., Lokulo-Sodipe, O., Horton, R., Siebert, R., Elbracht, M., Temple, I. K., Eggermann, T. & Mackay, D. J. G., 1 Jul 2018, In : Journal of Medical Genetics. 55, 7, p. 497-504 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
33 Citations (Scopus)
276 Downloads (Pure)

Mature subcutaneous and visceral adipocyte concentrations of adiponectin are highly correlated in prepubertal children and inversely related to body mass index standard deviation score

Sabin, M. A., Holly, J. M. P., Hamilton-Shield, J. P., Turner, S. J., Grohmann, M. J., Stewart-Paton, C. E. H. & Crowne, E. C., 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 1, p. 332 - 335 4 p.

Research output: Contribution to journalArticle (Academic Journal)

22 Citations (Scopus)

Mosaic paternal uniparental isodisomy and an ABCC8 gene mutation in a patient with permanent neonatal diabetes and hemihypertrophy

Shield, JPH., 2008, In : Diabetes. 57, p. 255 - 258

Research output: Contribution to journalArticle (Academic Journal)

15 Citations (Scopus)

Mutations in ATP-Sensitive K+ Channel Genes Cause Transient Neonatal Diabetes and Permanent Diabetes in Childhood or Adulthood

Flanagan, SE., Patch, AM., Mackay, DJ., Edghill, EL., Gloyn, AL., Robinson, D., Shield, JPH., Temple, IK., Ellard, SE. & Hattersley, AT., Jul 2007, In : Diabetes. 56 (7), p. 1930 - 1937 8 p.

Research output: Contribution to journalArticle (Academic Journal)

237 Citations (Scopus)

Mutations in NLRP5 are associated with reproductive wastage and multilocus imprinting disorders in humans

Docherty, L. E., Rezwan, F. I., Poole, R. L., Turner, C. L. S., Kivuva, E., Maher, E. R., Smithson, S. F., Hamilton-Shield, J. P., Patalan, M., Gizewska, M., Peregud-Pogorzelski, J., Beygo, J., Buiting, K., Horsthemke, B., Soellner, L., Begemann, M., Eggermann, T., Baple, E., Mansour, S., Temple, I. K. & 1 others, Mackay, D. J. G., 1 Sep 2015, In : Nature Communications. 6, 8086.

Research output: Contribution to journalArticle (Academic Journal)

72 Citations (Scopus)

Neonatal diabetes Mellitus, a disorder of imprinting

Temple, IK. & Hamilton-Shield, JP., 2002, In : Journal of Medical Genetics. 39, p. 872 - 875

Research output: Contribution to journalArticle (Academic Journal)

Normalizing Eating Behavior Reduces Body Weight and Improves Gastrointestinal Hormonal Secretion in Obese Adolescents

Galhardo, J., Hunt, LP., Lightman, SL., Sabin, MA., Bergh, C., Sodersten, P. & Shield, JPH., Feb 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 2, 9 p., E193.

Research output: Contribution to journalArticle (Academic Journal)

40 Citations (Scopus)
Open Access
File
38 Downloads (Pure)

Obesity in adolescents with chronic fatigue syndrome: an observational study

Norris, T., Hawton, K., Hamilton-Shield, J. & Crawley, E., 1 Jan 2017, In : Archives of Disease in Childhood. 102, 1, p. 35-39 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
7 Citations (Scopus)
340 Downloads (Pure)

Overview of neonatal diabetes

Hamilton-Shield, J. P., 2007, In : Endocr Dev. 12, p. 12-23 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Overweight and obesity in children aged 3-13 years in urban Cameroon: a cross-sectional study of prevalence and association with socio-economic status

Choukem, S-P., Kamdeu-Chedeu, J., Leary, S. D., Mboue-Djieka, Y., Nebongo, D. N., Akazong, C., Mapoure, Y. N., Hamilton-Shield, J. P., Gautier, J-F. & Mbanya, J. C., 1 Feb 2017, In : BMC Obesity. 4, 8 p., 7.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
12 Citations (Scopus)
314 Downloads (Pure)

Pancreatic hypoplasia presenting with neonatal diabetes mellitus in association with congenital heart defect and developmental delay

Balasubramanian, M., Shield, JPH., Acerini, CL., Walker, J., Ellard, S., Marchand, M., Polak, M., Vaxillaire, M., Crolla, JA., Bunyan, DJ., Mackay, DJ. & Temple, IK., Feb 2010, In : American Journal of Medical Genetics, Part A. 152A(2), p. 340 - 346 7 p.

Research output: Contribution to journalArticle (Academic Journal)

10 Citations (Scopus)

Parental beliefs about portion size, not children's own beliefs, predict child BMI

Potter, C., Ferriday, D., Griggs, R. L., Hamilton-Shield, J. P., Rogers, P. J. & Brunstrom, J. M., Apr 2018, In : Pediatric Obesity. 13, 4, p. 232-238 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
7 Citations (Scopus)
284 Downloads (Pure)
29 Citations (Scopus)

Physical activity patterns in non-obese and obese children assessed using minute-by-minute accelerometry

Page, AS., Cooper, AR., Stamatakis, E., Foster, LJ., Crowne, EC., Sabin, MA. & Shield, JPH., Sep 2005, In : International Journal of Obesity. 29 (9), p. 1070 - 1076 7 p.

Research output: Contribution to journalArticle (Academic Journal)

110 Citations (Scopus)

Polycystic Kidney Disease with Hyperinsulinemic Hypoglycemia Caused by a Promoter Mutation in Phosphomannomutase 2

Cabezas, O. R., Flanagan, S. E., Stanescu, H., García-Martínez, E., Caswell, R., Lango-Allen, H., Antón-Gamero, M., Argente, J., Bussell, A. M., Brandli, A., Cheshire, C., Crowne, E., Dumitriu, S., Drynda, R., Hamilton-Shield, J. P., Hayes, W., Hofherr, A., Iancu, D., Issler, N., Jefferies, C. & 26 others, Jones, P., Johnson, M., Kesselheim, A., Klootwijk, E., Koettgen, M., Lewis, W., Martos, J. M., Mozere, M., Norman, J., Patel, V., Parrish, A., Pérez-Cerdá, C., Pozo, J., Rahman, S. A., Sebire, N., Tekman, M., Turnpenny, P. D., Van'T Hoff, W., Viering, D. H. H. M., Weedon, M. N., Wilson, P., Guay-Woodford, L., Kleta, R., Hussain, K., Ellard, S. & Bockenhauer, D., 1 Aug 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2529-2539 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
44 Citations (Scopus)
333 Downloads (Pure)

Practitioners' views on managing childhood obesity in primary care: a qualitative study

Turner, K., Hamilton-Shield, J. P. & Salisbury, C., Nov 2009, In : British Journal of General Practice. 59(568), p. 856 - 862 7 p.

Research output: Contribution to journalArticle (Academic Journal)

38 Citations (Scopus)

Protection from clinical peripheral sensory neuropathy in Alström syndrome in contrast to early-onset type 2 diabetes

Paisey, RB., Paisey, RM., Thomson, MP., Bower, L., Maffei, P., Shield, JPH., Barnett, S. & Marshall, JD., Mar 2009, In : Diabetes Care. 32(3), p. 462 - 464 3 p.

Research output: Contribution to journalArticle (Academic Journal)

18 Citations (Scopus)

Reduced beta-cell reserve and pancreatic volume in survivors of childhood acute lymphoblastic leukaemia treated with bone marrow transplantation and total body irradiation

Wei, C., Thyagiarajan, M., Hunt, L., Cox, R., Bradley, K., Elson, R., Hamilton-Shield, J., Stevens, M. & Crowne, E., Jan 2015, In : Clinical Endocrinology. 82, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)

Reduced insulin sensitivity in childhood survivors of haematopoietic stem cell transplantation is associated with lipodystropic and sarcopenic phenotypes

Wei, C., Thyagiarajan, M. S., Hunt, L. P., Hamilton-Shield, J. P., Stevens, M. C. G. & Crowne, E. C., Nov 2015, In : Pediatric Blood and Cancer. 62, 11, p. 1992-9 8 p.

Research output: Contribution to journalArticle (Academic Journal)

36 Citations (Scopus)

Reversible biological adaptations in obesity

Södersten, P., Bergh, C., Shield, J. & Lightman, S., May 2015, In : Lancet Diabetes and Endocrinology. 3, 5, p. 314

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)

Rising incidence of type 2 diabetes in children in the United Kingdom

Haines, L., Chong, WK., Lynn, R., Barrett, TG. & Shield, JPH., May 2007, In : Diabetes Care. 30 (5), p. 1097 - 1101 5 p.

Research output: Contribution to journalArticle (Academic Journal)

170 Citations (Scopus)

Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy

Lennon, R., Pons, D., Sabin, M. A., Wei, C., Hamilton-Shield, J. P., Coward, R. J., Tavaré, J. M., Mathieson, P. W., Saleem, M. A. & Welsh, G. I., Nov 2009, In : Nephrology Dialysis Transplantation. 24, 11, p. 3288 - 3296 9 p.

Research output: Contribution to journalArticle (Academic Journal)

102 Citations (Scopus)