Professor Julian P Hamilton-Shield

M.B.,Ch.B., M.D.(Bristol), M.R.C.P., FRCPCH

  • BS2 8AE

20002020

Research output per year

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Research Output

  • 125 Article (Academic Journal)
  • 9 Conference Contribution (Conference Proceeding)
  • 2 Letter (Academic Journal)
  • 2 Review article (Academic Journal)
2014

Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT): urinary screening and baseline biochemical and cardiovascular assessments

Marcovecchio, M. L., Woodside, J., Jones, T., Daneman, D., Neil, A., Prevost, T., Dalton, R. N., Deanfield, J., Dunger, D. B., Acerini, C., Anand, B., Barrett, T., Birrell, V., Campbell, F., Ackland, F., Cheetham, T., Cooper, C., Doughty, I., Dutta, A., Edge, J. & 25 others, Shield, J. P. H., Heywood, J., Leech, N., Mann, N., Parker, R., Rayman, G., Robinson, J. M., Russell-Taylor, M., Sankar, V., Thalange, N., Wilson, M., Bergman, P., Rodda, C., Cameron, F., Cotterill, A., Couper, J., Davis, E., Donaghue, K., Craig, M., King, B., Verge, C., Mahmud, F., Clarson, C., Curtis, J. & Sochett, E., 2014, In : Diabetes Care. 37, 3, p. 805-13 9 p.

Research output: Contribution to journalArticle (Academic Journal)

43 Citations (Scopus)

Changing eating behaviours to treat childhood obesity in the community using Mandolean: The Community Mandolean randomised controlled trial (ComMando) - A pilot study

Hamilton-Shield, J., Goodred, J., Powell, L. A., Thorn, J., Banks, J. P., Hollinghurst, S., Montgomery, A., Turner, K. & Sharp, D., Jul 2014, In : Health Technology Assessment. 18, 47, p. 1-75 75 p.

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)

Framework of outcome measures recommended for use in the evaluation of childhood obesity treatment interventions: the CoOR framework

Bryant, M., Ashton, L., Nixon, J., Jebb, S., Wright, J., Roberts, K., Brown, J. & CoOR Scientific advisory group, Dec 2014, In : Pediatric Obesity. 9, 6, p. e116-e131 16 p.

Research output: Contribution to journalArticle (Academic Journal)

10 Citations (Scopus)

Portion size selection and snack food preferences; inter-relationships between parent and child BMI

Potter, C. M., Ferriday, D., Griggs, R. L., Hamilton-Shield, J. P., Byrom, O., Rogers, P. J. & Brunstrom, J. M., 2014, Appetite. Vol. 83. p. 349

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Predictors of aberrant eating and child BMI percentile

Griggs, R. L., Ferriday, D., Potter, C. M., Hamilton-Shield, J. P., Byrom, O., Rogers, P. J. & Brunstrom, J. M., 2014, Appetite. Vol. 83. p. 349

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

The HNF4A R76W mutation causes atypical dominant Fanconi syndrome in addition to a β cell phenotype

Hamilton, A., Bingham, C., McDonald, TJ., Cook, PR., Caswell, RC., Weedon, MN., Oram, RA., Shields, BM., Shepherd, M., Inward, C. D., Hamilton-Shield, J. P., Kohlhase, J., Ellard, S. & Hattersley, AT., Mar 2014, In : Journal of Medical Genetics. 51, 3, 5 p., 165-169.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
37 Citations (Scopus)
279 Downloads (Pure)
2013

Can foster care ever be justified for weight management?

Williams, GM., Bredow, M. T., Barton, J., Pryce, R. & Hamilton-Shield, J. P., 2013, In : Archives of Disease in Childhood.

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)

Clinical and Molecular Characterisation of 300 patients with Congenital Hyperinsulinism

Kapoor, R. R., Flanagan, S. E., Arya, V. B., Hamilton-Shield, J. P., Ellard, S. & Hussain, K., 2013, In : European Journal of Endocrinology.

Research output: Contribution to journalArticle (Academic Journal)

105 Citations (Scopus)

Clinical and Molecular Characterisation Of Hyperinsulinaemic Hypoglycaemia In Infants Born Small-For-Gestational Age

Arya, V. B., Flanagan, S. E., Kumaran, A., Hamilton-Shield, J. P., Ellard, S., Hussain, K. & Kapoor, R. R., Jul 2013, In : Archives of Disease in Childhood: Fetal and Neonatal Edition. 98, 4, p. F356-F359 4 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
24 Citations (Scopus)
310 Downloads (Pure)

Clinical presentation of 6q24 transient neonatal diabetes mellitus (6q24 TNDM) and genotype-phenotype correlation in an international cohort of patients

Louise E, D., S, K., A, L., E, H., L, H., SE, F., S, E. (ed.), AT, H., Hamilton-Shield, J. P., S, E., DJ, M. & IK, T., Apr 2013, In : Diabetologia. 56, 4, p. 758–762 5 p.

Research output: Contribution to journalArticle (Academic Journal)

67 Citations (Scopus)

Cost and effectiveness of treatment options for childhood obesity

Hollinghurst, S. P., Hunt, L. P., Banks, J. P., Sharp, D. J. & Hamilton-Shield, J. P., 2013, In : International Journal of Pediatric Obesity.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

Early-Onset, Coexisting Autoimmunity and Decreased HLA-Mediated Susceptibility Are the Characteristics of Diabetes in Down Syndrome

Aitken, R. J., Mehers, K. L., Williams, A. J. K., Brown, J. L., Bingley, P. J., Holl, R. W., Rohrer, T. P., Schober, E., Abdul-Rasoul, M. M., Hamilton-Shield, J. P. & Gillespie, K. M., May 2013, In : Diabetes Care. 36, 5, p. 1181-1185 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
16 Citations (Scopus)
247 Downloads (Pure)

High intensity interval running enhances measures of physical fitness but not metabolic measures of cardiovascular disease risk in healthy adolescents

Buchan, DS., Ollis, S., Young, JD., Cooper, SM., Hamilton-Shield, J. P. & Baker, JS., 24 May 2013, In : BMC Public Health. 13, 12 p., 498.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
33 Citations (Scopus)
256 Downloads (Pure)
19 Citations (Scopus)

KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation

Pearce, LR., Atanassova, N., Banton, MC., Bottomley, B., van der Klaauw, AA., Revelli, JP., Hendricks, A., Keogh, JM., Henning, E., Doree, D., Jeter-Jones, S., Gang, S., Bochukova, EG., Bounds, R., Ashford, S., Gayton, E., Hindmarsh, PC., Hamilton-Shield, J. P., Crowne, E. C., Barford, D. & 7 others, Wareham, NJ., consortium, UKK., O'Rahilly, S., Murphy, MP., Powell, DR., Barroso, I. & Farooqi, IS., 2013, In : Cell. S0092-8674, (13)

Research output: Contribution to journalArticle (Academic Journal)

92 Citations (Scopus)

Longitudinal changes in body mass index following renal transplantation in UK children

Plumb, L., Pitcher, D., Tse, Y., Hamilton-Shield, J. P., Inward, C. & Sinha, MD., 2013, In : Nephrology Dialysis Transplantation.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

The impact of hyperglycemia on risk of infection and early death during induction therapy for acute lymphoblastic leukemia (ALL)

Dare, JM., Moppett, JP., Hamilton-Shield, J. P., Hunt, L. P. & Stevens, MC., 2013, In : Pediatric Blood and Cancer.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)
2012

Assessment of childhood obesity in secondary care: OSCA consensus statement. A review

Viner, RM., White, B., Barrett, T., Candy, DC., Gibson, P., Gregory, JW., Matyka, K., Ong, K., Roche, E., Rudolf, MC., Shaikh, G., Shield, JPH. & Wales, JK., Jun 2012, In : Archives of Disease in Childhood: Education and Practice Edition. 97(3), p. 98 - 105

Research output: Contribution to journalArticle (Academic Journal)

Children eat their school lunch too quickly: an exploratory study of the effect on food intake

Zandian, M., Ioakimidis, I., Bergstrom, J., Brodin, U., Bergh, C., Leon, M., Hamilton-Shield, J. P. & Sodersten, P., 14 May 2012, In : BMC Public Health. 12, 8 p., 351.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
18 Citations (Scopus)
201 Downloads (Pure)
23 Citations (Scopus)

How does physical activity and fitness influence glycaemic control in young people with type 1 diabetes?

Cuenca-García, M., Jago, R., Hamilton-Shield, J. P. & Burren, C. P., Oct 2012, In : Diabetic Medicine. 29, 10, p. 369-376

Research output: Contribution to journalArticle (Academic Journal)

26 Citations (Scopus)

Is healthy eating for obese children necessarily more costly for families?

Banks, J. P., Williams, J., Cumberlidge, T., Cimonetti, T., Sharp, D. J. & Shield, JPH., Jan 2012, In : British Journal of General Practice. 62(594), p. e1 - e5

Research output: Contribution to journalArticle (Academic Journal)

15 Citations (Scopus)

Normalizing Eating Behavior Reduces Body Weight and Improves Gastrointestinal Hormonal Secretion in Obese Adolescents

Galhardo, J., Hunt, LP., Lightman, SL., Sabin, MA., Bergh, C., Sodersten, P. & Shield, JPH., Feb 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 2, 9 p., E193.

Research output: Contribution to journalArticle (Academic Journal)

38 Citations (Scopus)

Serum levels of pigment epithelium-derived factor (PEDF) are positively associated with acanthosis nigricans in obese adolescents

Galhardo, M. J., Hunt, LP. & Shield, JPH., Jul 2012, In : Diabetic Medicine. 29, 7, p. e117-20

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)
2011

3-Hydroxyisobutyrate aciduria and mutations in the ALDH6A1 gene coding for methylmalonate semialdehyde dehydrogenase

Sass, JO., Walter, M., Shield, JPH., Atherton, AM., Garg, U., Scott, D., Woods, CG. & Smith, LD., Aug 2011, In : Journal of Inherited Metabolic Disease.

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)

Barriers engaging families and GPs in childhood weight management strategies

Banks, J., Shield, JPH. & Sharp, D., Aug 2011, In : British Journal of General Practice. 61, p. 492 - 497 6 p.

Research output: Contribution to journalArticle (Academic Journal)

10 Citations (Scopus)
4 Citations (Scopus)

Hyperinsulinaemic hypoglycaemia and diabetes mellitus due to dominant ABCC8/KCNJ11 mutations

Kapoor, RR., Flanagan, SE., James, CT., McKiernan, J., Thomas, AM., Harmer, SC., Hamilton-Shield, J. P., Tinker, A., Ellard, S. & Hussain, K., Oct 2011, In : Diabetologia. 54, 10, p. 2575-2583 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
35 Citations (Scopus)
231 Downloads (Pure)
29 Citations (Scopus)
5 Citations (Scopus)
5 Citations (Scopus)
2010

6q24 transient neonatal diabetes

Temple, IK. & Shield, JPH., Sep 2010, In : Reviews in Endocrine and Metabolic Disorders. 11(3), p. 199 - 204 6 p.

Research output: Contribution to journalArticle (Academic Journal)

46 Citations (Scopus)

Abnormal liver function in children with metabolic syndrome from a UK-based obesity clinic

Wei, C., Ford, A., Hunt, LP., Crowne, E. & Shield, JPH., Nov 2010, In : Archives of Disease in Childhood. 96(11), p. 1003 - 1007 4 p.

Research output: Contribution to journalArticle (Academic Journal)

19 Citations (Scopus)

A double heterozygote for familial hypercholesterolaemia and familial defective apolipoprotein B-100

Taylor, A., Bayly, G., Patel, K., Yarram, L., Williams, M., Hamilton-Shield, J., Humphries, S. E. & Norbury, G., Sep 2010, In : Annals of Clinical Biochemistry. 47, Pt 5, p. 487-90 4 p.

Research output: Contribution to journalArticle (Academic Journal)

12 Citations (Scopus)

Diazoxide-responsive hyperinsulinemic hypoglycemia caused by HNF4A gene mutations

Flanagan, SE., Kapoor, RR., Mali, G., Cody, D., Murphy, N., Schwahn, B., Sianhanidou, T., Banerjee, I., Akcay, T., Rubio-Cabezas, O., Shield, JPH., Hussain, K. & Ellard, S., May 2010, In : European Journal of Endocrinology. 162(5), p. 987 - 992 6 p.

Research output: Contribution to journalArticle (Academic Journal)

82 Citations (Scopus)

European Medicines Agency withdrawal for sibutramine

Galhardo, J., Davis, N., Matthai, S. & Shield, JPH., Oct 2010, In : Archives of Disease in Childhood. 95(10), p. 856 - 856 1 p.

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)

Hyperglycaemia confers resistance to chemotherapy on breast cancer cells: the role of fatty acid synthase

Zeng, L., Biernacka, K., Holly, JMP., Jarrett, CE., Morrison, A., Morgan, A., Winters, ZE., Foulstone, EJ., Hamilton-Shield, J. P. & Perks, CM., 1 Jun 2010, In : Endocrine-Related Cancer. 17, 2, p. 539 - 551 13 p.

Research output: Contribution to journalArticle (Academic Journal)

81 Citations (Scopus)

Large rare chromosomal deletions associated with severe early onset obesity

Ismaa, F., Elena Bochukova, N. V., Julia Keogh, N. V., Elana Henning, N. V., Carolin Purmann, N. V., Ni Huang, N. V., Kasia Blaszczyk, N. V., Sadia Saeed, N. V., Shield, JPH., Jill Clayton-Smith, N. V., Stephen O'Rahilly, N. V. & Matthew, H., 4 Feb 2010, In : Nature. 463, p. 666-670

Research output: Contribution to journalArticle (Academic Journal)

365 Citations (Scopus)

Pancreatic hypoplasia presenting with neonatal diabetes mellitus in association with congenital heart defect and developmental delay

Balasubramanian, M., Shield, JPH., Acerini, CL., Walker, J., Ellard, S., Marchand, M., Polak, M., Vaxillaire, M., Crolla, JA., Bunyan, DJ., Mackay, DJ. & Temple, IK., Feb 2010, In : American Journal of Medical Genetics, Part A. 152A(2), p. 340 - 346 7 p.

Research output: Contribution to journalArticle (Academic Journal)

10 Citations (Scopus)

Treatment of childhood obesity by retraining eating behaviour: randomised controlled trial

Ford, AL., Bergh, C., Soldersten, P., Sabin, M., Hollinghurst, S., Hunt, LP. & Hamilton-Shield, J. P., 5 Jan 2010, In : BMJ. 340, p. b5388

Research output: Contribution to journalArticle (Academic Journal)

114 Citations (Scopus)

What reduction in BMI SDS is required in obese adolescents to improve body composition and cardiometabolic health?

Ford, AL., Hunt, LP., Cooper, AR. & Shield, JPH., Apr 2010, In : Archives of Disease in Childhood. 95, 4, p. 256 - 261 6 p.

Research output: Contribution to journalArticle (Academic Journal)

167 Citations (Scopus)
2009
16 Citations (Scopus)

Clinical heterogeneity in patients with FOXP3 mutations presenting with permanent neonatal diabetes

Rubio-Cabezas, O., Minton, JA., Caswell, R., Shield, JPH., Deiss, D., Sumnik, Z., Cayssials, A., Herr, M., Loew, A., Lewis, V., Ellard, S. & Hattersley, AT., Jan 2009, In : Diabetes Care. 32(1), p. 111 - 116 6 p.

Research output: Contribution to journalArticle (Academic Journal)

76 Citations (Scopus)

Hypercholesterolaemia in children guidelines review

Baumer, JH. & Shield, JPH., Jun 2009, In : Archives of Disease in Childhood: Education and Practice Edition. 94(3), p. 84 - 86 3 p.

Research output: Contribution to journalArticle (Academic Journal)

5 Citations (Scopus)

Hyperinsulinism-hyperammonaemia syndrome: novel mutations in the GLUD1 gene and genotype-phenotype correlations

Kapoor, RR., Flanagan, SE., Fulton, P., Chakrapani, A., Chadefaux, B., Ben-Omran, T., Banerjee, I., Shield, JPH., Ellard, S. & Hussain, K., Nov 2009, In : European Journal of Endocrinology. 161(5), p. 731 - 735 5 p.

Research output: Contribution to journalArticle (Academic Journal)

62 Citations (Scopus)

Management and one year outcome for UK children with type 2 diabetes

Shield, JPH., 2009, In : Archives of Disease in Childhood. 94, p. 206 - 209

Research output: Contribution to journalArticle (Academic Journal)

Practitioners' views on managing childhood obesity in primary care: a qualitative study

Turner, K., Hamilton-Shield, J. P. & Salisbury, C., Nov 2009, In : British Journal of General Practice. 59(568), p. 856 - 862 7 p.

Research output: Contribution to journalArticle (Academic Journal)

38 Citations (Scopus)

Protection from clinical peripheral sensory neuropathy in Alström syndrome in contrast to early-onset type 2 diabetes

Paisey, RB., Paisey, RM., Thomson, MP., Bower, L., Maffei, P., Shield, JPH., Barnett, S. & Marshall, JD., Mar 2009, In : Diabetes Care. 32(3), p. 462 - 464 3 p.

Research output: Contribution to journalArticle (Academic Journal)

18 Citations (Scopus)

Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy

Lennon, R., Pons, D., Sabin, M. A., Wei, C., Hamilton-Shield, J. P., Coward, R. J., Tavaré, J. M., Mathieson, P. W., Saleem, M. A. & Welsh, G. I., Nov 2009, In : Nephrology Dialysis Transplantation. 24, 11, p. 3288 - 3296 9 p.

Research output: Contribution to journalArticle (Academic Journal)

101 Citations (Scopus)