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Research Output

2007

Correction: Interpretation of random effects meta-analysis in decision models

Welton, N. J., White, I. R., Lu, G., Higgins, J. P. T., Hilden, J. & Ades, A. E., 1 Mar 2007, In : Medical Decision Making. 27, 2, p. 212-214 3 p.

Research output: Contribution to journalLetter (Academic Journal)

16 Citations (Scopus)
2008

Imputation methods for missing outcome data in meta-analysis of clinical trials

Higgins, J. P. T., White, I. R. & Wood, A. M., 2008, In : Clinical Trials. 5, 3, p. 225-39 15 p.

Research output: Contribution to journalArticle (Academic Journal)

186 Citations (Scopus)

Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis

Sagoo, G. S., Tatt, I., Salanti, G., Butterworth, AS., Sarwar, N., van Maarle, M., Jukema, JW., Wiman, B., Kastelein, JJP., Bennet, A., de Faire, U., Danesh, J. & Higgins, J. P. T., 2008, In : American Journal of Epidemiology. 168, 11, p. 1233-1246 14 p.

Research output: Contribution to journalArticle (Academic Journal)

97 Citations (Scopus)
2009

A re-evaluation of random-effects meta-analysis

Higgins, J. P. T., Thompson, SG. & Spiegelhalter, DJ., Jan 2009, In : Journal of the Royal Statistical Society: Series A. 172, 1, p. 137-159 23 p.

Research output: Contribution to journalArticle (Academic Journal)

1001 Citations (Scopus)

Array CGH in patients with learning disability (mental retardation) and congenital anomalies: updated systematic review and meta-analysis of 19 studies and 13,926 subjects

Sagoo, G. S., Butterworth, A. S., Sanderson, S., Shaw-Smith, C., Higgins, J. P. T. & Burton, H., Mar 2009, In : Genetics in Medicine. 11, 3, p. 139-46 8 p.

Research output: Contribution to journalArticle (Academic Journal)

161 Citations (Scopus)

Comparative efficacy and acceptability of 12 new-generation antidepressants: A multiple-treatments meta-analysis

Cipriani, A., Furukawa, T. A., Salanti, G., Geddes, J. R., Higgins, J. P. T., Churchill, R. C., Watanabe, N., Nakagawa, A., Omori, I. M., McGuire, H., Tansella, M. & Barbui, C., 28 Feb 2009, In : Lancet. 373, 9665, p. 746 - 758 12 p.

Research output: Contribution to journalArticle (Academic Journal)

1154 Citations (Scopus)

Disagreements in meta-analyses using outcomes measured on continuous or rating scales: observer agreement study

Tendal, B., Higgins, J. P. T., Jüni, P., Hróbjartsson, A., Trelle, S., Nüesch, E., Wandel, S., Jørgensen, A. W., Gesser, K., Ilsøe-Kristensen, S. & Gøtzsche, P. C., 2009, In : BMJ. 339, p. b3128

Research output: Contribution to journalArticle (Academic Journal)

31 Citations (Scopus)

Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases

Khoury, M. J., Bertram, L., Boffetta, P., Butterworth, A. S., Chanock, S. J., Dolan, S. M., Fortier, I., Garcia-Closas, M., Gwinn, M., Higgins, J. P. T., Janssens, A. C. J. W., Ostell, J., Owen, R. P., Pagon, R. A., Rebbeck, T. R., Rothman, N., Bernstein, J. L., Burton, P. R., Campbell, H., Chockalingam, A. & 8 others, Furberg, H., Little, J., O'Brien, T. R., Seminara, D., Vineis, P., Winn, D. M., Yu, W. & Ioannidis, J. P. A., 1 Aug 2009, In : American Journal of Epidemiology. 170, 3, p. 269-79 11 p.

Research output: Contribution to journalArticle (Academic Journal)

116 Citations (Scopus)

Making the best use of available evidence: the case of new generation antidepressants: a response to: are all antidepressants equal?

Barbui, C., Cipriani, A., Furukawa, T. A., Salanti, G., Higgins, J. P. T., Churchill, R., Watanabe, N., Nakagawa, A., Omori, I. M. & Geddes, J. R., Nov 2009, In : Evidence-Based Mental Health. 12, 4, p. 101-4 4 p.

Research output: Contribution to journalArticle (Academic Journal)

2 Citations (Scopus)

STrengthening the REporting of Genetic Association studies (STREGA): an extension of the STROBE Statement

Little, J., Higgins, J. P. T., Ioannidis, J. P. A., Moher, D., Gagnon, F., von Elm, E., Khoury, M. J., Cohen, B., Davey Smith, G., Grimshaw, J., Scheet, P., Gwinn, M., Williamson, R. E., Zou, G. Y., Hutchings, K., Johnson, C. Y., Tait, V., Wiens, M., Golding, J., van Duijn, C. & 10 others, McLaughlin, J., Paterson, A., Wells, G., Fortier, I., Freedman, M., Zecevic, M., King, R., Infante-Rivard, C., Stewart, A. & Birkett, N., 3 Feb 2009, In : Annals of Internal Medicine. 150, 3, p. 206-15 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Systematic reviews of genetic association studies. Human Genome Epidemiology Network

Sagoo, G. S., Little, J. & Higgins, J. P. T., 3 Mar 2009, In : PLoS Medicine. 6, 3, p. e28

Research output: Contribution to journalArticle (Academic Journal)

117 Citations (Scopus)
2010

Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: two meta-analyses of individual patient data

Arriagada, R., Auperin, A., Burdett, S., Higgins, J. P., Johnson, D. H., Le Chevalier, T., Le Pechoux, C., Parmar, M. K. B., Pignon, J. P., Souhami, R. L., Stephens, R. J., Stewart, L. A., Tierney, J. F., Tribodet, H., van Meerbeeck, J. & NSCLC Meta-analyses Collaborative Group, 10 Apr 2010, In : Lancet. 375, 9722, p. 1267-77 11 p.

Research output: Contribution to journalArticle (Academic Journal)

366 Citations (Scopus)

Challenges in the use of literature-based meta-analysis to examine gene-environment interactions

Palla, L., Higgins, J. P. T., Wareham, N. J. & Sharp, S. J., 1 Jun 2010, In : American Journal of Epidemiology. 171, 11, p. 1225-32 8 p.

Research output: Contribution to journalArticle (Academic Journal)

36 Citations (Scopus)

Comments on 'Empirical vs natural weighting in random effects meta-analysis'

Thompson, S. G. & Higgins, J. P. T., 30 May 2010, In : Statistics in Medicine. 29, 12, p. 1270-1; discussion 1272-81

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)

Coronary heart disease

Butterworth, A. S., Higgins, J. P. T., Sarwar, N. & Danesh, J., 1 May 2010, Human Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition. Oxford University Press

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

Health-related lifestyle in adults and children with primary immune thrombocytopenia (ITP)

Sarpatwari, A., Watson, S., Erqou, S., Anderson, H., Grainger, J., Higgins, J. P. T. & Newland, A. C., Oct 2010, In : British Journal of Haematology. 151, 2, p. 189-191 3 p.

Research output: Contribution to journalArticle (Academic Journal)

14 Citations (Scopus)

Human genome epidemiology: The road map revisited

Khoury, M. J., Bedrosian, S. R., Gwinn, M., Little, J., Higgins, J. P. T. & Ioannidis, J. P. A., 1 May 2010, Human Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition. Oxford University Press

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

6 Citations (Scopus)

Human Genome Epidemiology: Building the evidence for using genetic information to improve health and prevent disease: Second Edition

Khoury, M. J., Bedrosian, S. R., Gwinn, M., Little, J., Higgins, J. P. T. & Ioannidis, J. P. A., 1 May 2010, Oxford University Press. 704 p.

Research output: Book/ReportAuthored book

6 Citations (Scopus)

Integration of the evidence on gene-disease associations: Methods of HuGE reviews

Higgins, J. P. T. & Little, J., 1 May 2010, Human Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition. Oxford University Press

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis

Gouda, H. N., Sagoo, G. S., Harding, A-H., Yates, J., Sandhu, M. S. & Higgins, J. P. T., 15 Mar 2010, In : American Journal of Epidemiology. 171, 6, p. 645-55 11 p.

Research output: Contribution to journalArticle (Academic Journal)

158 Citations (Scopus)
2011

Characteristics of meta-analyses and their component studies in the Cochrane Database of Systematic Reviews: a cross-sectional, descriptive analysis

Davey, J., Turner, R. M., Clarke, M. J. & Higgins, J. P. T., 2011, In : BMC Medical Research Methodology. 11, p. 160

Research output: Contribution to journalArticle (Academic Journal)

181 Citations (Scopus)

Expressing findings from meta-analyses of continuous outcomes in terms of risks

Anzures-Cabrera, J., Sarpatwari, A. & Higgins, J. P., 2011, In : Statistics in Medicine. 30, 25, p. 2967-85 19 p.

Research output: Contribution to journalArticle (Academic Journal)

25 Citations (Scopus)

GRADE guidelines: 7. Rating the quality of evidence--inconsistency

Guyatt, G. H., Oxman, A. D., Kunz, R., Woodcock, J., Brozek, J., Helfand, M., Alonso-Coello, P., Glasziou, P., Jaeschke, R., Akl, E. A., Norris, S., Vist, G., Dahm, P., Shukla, V. K., Higgins, J., Falck-Ytter, Y., Schünemann, H. J. & GRADE Working Group, 2011, In : Journal of Clinical Epidemiology. 64, 12, p. 1294-302 9 p.

Research output: Contribution to journalArticle (Academic Journal)

902 Citations (Scopus)

Individual patient data meta-analysis of time-to-event outcomes: one-stage versus two-stage approaches for estimating the hazard ratio under a random effects model

Bowden, J., Tierney, J. F., Simmonds, M., Copas, A. J. & Higgins, J. P., Sep 2011, In : Research Synthesis Methods. 2, 3, p. 150-62 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Interpretation of random effects meta-analyses

Riley, R. D., Higgins, J. P. T. & Deeks, J. J., 2011, In : BMJ. 342, p. d549

Research output: Contribution to journalArticle (Academic Journal)

954 Citations (Scopus)

Lack of evidence for the efficacy of memantine in mild Alzheimer disease

Schneider, L. S., Dagerman, K. S., Higgins, J. P. T. & McShane, R., 2011, In : Archives of Neurology. 68, 8, p. 991-8 8 p.

Research output: Contribution to journalArticle (Academic Journal)

178 Citations (Scopus)

Meta-analysis of time-to-event data: a comparison of two-stage methods

Simmonds, M. C., Tierney, J., Bowden, J. & Higgins, J. P., Sep 2011, In : Research Synthesis Methods. 2, 3, p. 139-49 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Multiplicity of data in trial reports and the reliability of meta-analyses: empirical study

Tendal, B., Nüesch, E., Higgins, J. P. T., Jüni, P. & Gøtzsche, P. C., 2011, In : BMJ. 343, p. d4829

Research output: Contribution to journalArticle (Academic Journal)

28 Citations (Scopus)

Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials

Sterne, J. A. C., Sutton, A. J., Ioannidis, J. P. A., Terrin, N., Jones, D. R., Lau, J., Carpenter, J., Rücker, G., Harbord, R. M., Schmid, C. H., Tetzlaff, J., Deeks, J. J., Peters, J., Macaskill, P., Schwarzer, G., Duval, S., Altman, D. G., Moher, D. & Higgins, J. P. T., 2011, In : BMJ. 343, p. d4002

Research output: Contribution to journalArticle (Academic Journal)

2290 Citations (Scopus)

Sequential methods for random-effects meta-analysis

Higgins, J. P. T., Whitehead, A. & Simmonds, M., 2011, In : Statistics in Medicine. 30, 9, p. 903-21 19 p.

Research output: Contribution to journalArticle (Academic Journal)

181 Citations (Scopus)

The Cochrane Collaboration's tool for assessing risk of bias in randomised trials

Higgins, J. P. T., Altman, D. G., Gøtzsche, P. C., Jüni, P., Moher, D., Oxman, A. D., Savovic, J., Schulz, K. F., Weeks, L., Sterne, J. A. C. & Cochrane Bias Methods Group, 18 Oct 2011, In : BMJ. 343, p. d5928 9 p.

Research output: Contribution to journalArticle (Academic Journal)

10283 Citations (Scopus)
2012

Cognitive-behavioural interventions for children who have been sexually abused

Macdonald, G., Higgins, J. P. T., Ramchandani, P., Valentine, J. C., Bronger, L. P., Klein, P., O'Daniel, R., Pickering, M., Rademaker, B., Richardson, G. & Taylor, M., 2012, In : Cochrane Database of Systematic Reviews. 5, p. CD001930

Research output: Contribution to journalArticle (Academic Journal)

44 Citations (Scopus)
6 Citations (Scopus)

Estimating within-study covariances in multivariate meta-analysis with multiple outcomes

Wei, Y. & Higgins, J. P., 2012, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

48 Citations (Scopus)

Graphical augmentations to the funnel plot assess the impact of additional evidence on a meta-analysis

Langan, D., Higgins, J. P. T., Gregory, W. & Sutton, A. J., 2012, In : Journal of Clinical Epidemiology. 65, 5, p. 511-9 9 p.

Research output: Contribution to journalArticle (Academic Journal)

46 Citations (Scopus)

Non-invasive prenatal diagnostic test accuracy for fetal sex using cell-free DNA a review and meta-analysis

Wright, C. F., Wei, Y., Higgins, J. P. T. & Sagoo, G. S., 2012, In : BMC Research Notes. 5, p. 476

Research output: Contribution to journalArticle (Academic Journal)

52 Citations (Scopus)

Predicting the extent of heterogeneity in meta-analysis, using empirical data from the Cochrane Database of Systematic Reviews

Turner, R. M., Davey, J., Clarke, M. J., Thompson, S. G. & Higgins, J. P., 2012, In : International Journal of Epidemiology. 41, 3, p. 818-27 10 p.

Research output: Contribution to journalArticle (Academic Journal)

341 Citations (Scopus)

Two-stage meta-analysis of survival data from individual participants using percentile ratios

Barrett, J. K., Farewell, V. T., Siannis, F., Tierney, J. & Higgins, J. P. T., 2012, In : Statistics in Medicine. 31, 30, p. 4296-308 13 p.

Research output: Contribution to journalArticle (Academic Journal)

10 Citations (Scopus)
2013

An introduction to methodological issues when including non-randomized studies in systematic reviews on the effects of interventions.

Reeves, B. C., Higgins, J. P. T., Ramsey, C., Tugwell, P. & Wells, G. A., 24 Jan 2013, In : Research Synthesis Methods. 4, 1, p. 1-11

Research output: Contribution to journalArticle (Academic Journal)

Assessment of systematic effects of methodological characteristics on candidate genetic associations

Aljasir, B., Ioannidis, J. P. A., Yurkiewich, A., Moher, D., Higgins, J. P. T., Arora, P. & Little, J., 2013, In : Human Genetics. 132, 2, p. 167-78 12 p.

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)

Bayesian multivariate meta-analysis with multiple outcomes

Wei, Y. & Higgins, J. P. T., 2013, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

44 Citations (Scopus)

Checklists of methodological issues for review authors to consider when including non-randomized studies in systematic reviews.

Wells, G. A., Shea, B., Higgins, J. P. T., Sterne, J. A. C., Tugwell, P. & Reeves, B. C., Mar 2013, In : Research Synthesis Methods. 4, 1, p. 63-77

Research output: Contribution to journalArticle (Academic Journal)

Conceptual and technical challenges in network meta-analysis

Cipriani, A., Higgins, J. P. T., Geddes, J. R. & Salanti, G., 16 Jul 2013, In : Annals of Internal Medicine. 159, 2, p. 130-7 8 p.

Research output: Contribution to journalArticle (Academic Journal)

398 Citations (Scopus)

Evaluating the impact of imputations for missing participant outcome data in a network meta-analysis

Spineli, L. M., Higgins, J. P., Cipriani, A., Leucht, S. & Salanti, G., 2013, In : Clinical Trials.

Research output: Contribution to journalArticle (Academic Journal)

29 Citations (Scopus)

Evaluation of inconsistency in networks of interventions

Veroniki, A. A., Vasiliadis, H. S., Higgins, J. P. T. & Salanti, G., Feb 2013, In : International Journal of Epidemiology. 42, 1, p. 332-45 14 p.

Research output: Contribution to journalArticle (Academic Journal)

166 Citations (Scopus)

Graphical tools for network meta-analysis in STATA

Chaimani, A., Higgins, J. P. T., Mavridis, D., Spyridonos, P. & Salanti, G., 2013, In : PLoS ONE. 8, 10, p. e76654

Research output: Contribution to journalArticle (Academic Journal)

783 Citations (Scopus)

Issues relating to study design and risk of bias when including non-randomized studies in systematic reviews on the effects of interventions.

Higgins, J. P. T., Ramsey, C., Reeves, B. C., Shea, B., Valentine, J. C., Tugwell, P. & Wells, G. A., Mar 2013, In : Research Synthesis Methods. 4, 1, p. 12-25

Research output: Contribution to journalArticle (Academic Journal)

Meta-analysis and subgroups

Borenstein, M. & Higgins, J. P. T., Apr 2013, In : Prevention Science. 14, 2, p. 134-43 10 p.

Research output: Contribution to journalArticle (Academic Journal)

121 Citations (Scopus)

Planning future studies based on the conditional power of a meta-analysis

Roloff, V., Higgins, J. P. T. & Sutton, A. J., 2013, In : Statistics in Medicine. 32, 1, p. 11-24 14 p.

Research output: Contribution to journalArticle (Academic Journal)

34 Citations (Scopus)

Reporting of industry funded study outcome data: comparison of confidential and published data on the safety and effectiveness of rhBMP-2 for spinal fusion

Rodgers, M. A., Brown, J. V. E., Heirs, M. K., Higgins, J. P. T., Mannion, R. J., Simmonds, M. C. & Stewart, L. A., 2013, In : BMJ. 346, p. f3981

Research output: Contribution to journalArticle (Academic Journal)

51 Citations (Scopus)