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Research Output

Accounting for heterogeneity in meta-analysis using a multiplicative model—an empirical study

Mawdsley, D., Higgins, J., Sutton, A. J. & Abrams, K., Mar 2017, In : Research Synthesis Methods. 8, 1, p. 43–52 10 p.

Research output: Contribution to journalArticle (Academic Journal)

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6 Citations (Scopus)
257 Downloads (Pure)

A checklist designed to aid consistency and reproducibility of GRADE assessments: development and pilot validation

Meader, N., King, K., Llewellyn, A., Norman, G., Brown, J., Rodgers, M., Moe-Byrne, T., Higgins, J. P., Sowden, A. & Stewart, G., 24 Jul 2014, In : Systematic Reviews. 3, 1, p. 82

Research output: Contribution to journalArticle (Academic Journal)

210 Citations (Scopus)

A comparison of heterogeneity variance estimators in simulated random-effects meta-analyses

Langan, D., Higgins, J. P. T., Jackson, D., Bowden, J., Veroniki, A. A., Kontopantelis, E., Viechtbauer, W. & Simmonds, M., 6 Sep 2018, In : Research Synthesis Methods. 16 p.

Research output: Contribution to journalArticle (Academic Journal)

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43 Citations (Scopus)
138 Downloads (Pure)

A Cost-Effectiveness Analysis Of Novel Oral Anticoagulants For Acute Treatment And Secondary Prevention Of Venous Thromboembolic Disease

Bryden, P., Welton, N. J., Thom, H., Sterne, J., Bodalia, P., Davies, P., López-López, J., Okoli, G. N., Caldwell, D. M., Dias, S., Eaton, D., Higgins, J., Salisbury, C., Savovic, J., Sofat, R., Stephens-Boal, A., Hingorani, A. & Hollingworth, W., Nov 2015, In : Value in Health. 18, 7, p. A390

Research output: Contribution to journalArticle (Academic Journal)

A Cost-Effectiveness Analysis of Novel Oral Anticoagulants for Primary Prevention of Venous Thromboembolic Disease

Bryden, P., Welton, N. J., Thom, H., Sterne, J., Bodalia, P., Davies, P., López-López, J., Okoli, G. N., Caldwell, D. M., Dias, S., Eaton, D., Higgins, J., Salisbury, C., Savovic, J., Sofat, R., Stephens-Boal, A., Hingorani, A. & Hollingworth, W., Nov 2015, In : Value in Health. 18, 7, p. A339-40

Research output: Contribution to journalArticle (Academic Journal)

Additional considerations are required when preparing a protocol for a systematic review with multiple interventions

Chaimani, A., Caldwell, D., Li, T., Higgins, J. & Salanti, G., Mar 2017, In : Journal of Clinical Epidemiology. 83, p. 65–74 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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38 Citations (Scopus)
360 Downloads (Pure)

A design-by-treatment interaction model for network meta-analysis with random inconsistency effects

Jackson, D., Barrett, J. K., Rice, S., White, I. R. & Higgins, J. P. T., 29 Apr 2014, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

103 Citations (Scopus)

Adjusting trial results for biases in meta-analysis: combining data-based evidence on bias with detailed trial assessment

Rhodes, KM., Savović, J., Elbers, G., Jones, H., Higgins, J., Sterne, J., Welton, N. & Turner, RM., 4 Jul 2019, In : Journal of the Royal Statistical Society: Series A. 183, 1, p. 193-209 17 p.

Research output: Contribution to journalArticle (Academic Journal)

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115 Downloads (Pure)

Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: two meta-analyses of individual patient data

Arriagada, R., Auperin, A., Burdett, S., Higgins, J. P., Johnson, D. H., Le Chevalier, T., Le Pechoux, C., Parmar, M. K. B., Pignon, J. P., Souhami, R. L., Stephens, R. J., Stewart, L. A., Tierney, J. F., Tribodet, H., van Meerbeeck, J. & NSCLC Meta-analyses Collaborative Group, 10 Apr 2010, In : Lancet. 375, 9722, p. 1267-77 11 p.

Research output: Contribution to journalArticle (Academic Journal)

366 Citations (Scopus)

Adjuvant chemotherapy for resected early-stage non-small cell lung cancer

Burdett, S., Pignon, J. P., Tierney, J., Tribodet, H., Stewart, L., Le Pechoux, C., Aupérin, A., Le Chevalier, T., Stephens, R. J., Arriagada, R., Higgins, J. P., Johnson, D. H., Van Meerbeeck, J., Parmar, M. K., Souhami, R. L., Bergman, B., Douillard, J-Y., Dunant, A., Endo, C., Girling, D. & 21 others, Kato, H., Keller, S. M., Kimura, H., Knuuttila, A., Kodama, K., Komaki, R., Kris, M. G., Lad, T., Mineo, T., Piantadosi, S., Rosell, R., Scagliotti, G., Seymour, L. K., Shepherd, F. A., Sylvester, R., Tada, H., Tanaka, F., Torri, V., Waller, D., Liang, Y. & for the Non‐Small Cell Lung Cancer Collaborative Group, 2 Mar 2015, In : Cochrane Database of Systematic Reviews. 3, p. CD011430

Research output: Contribution to journalArticle (Academic Journal)

103 Citations (Scopus)

A general framework for the use of logistic regression models in meta-analysis

Simmonds, M. C. & Higgins, J. P., 12 May 2014, In : Statistical Methods in Medical Research.

Research output: Contribution to journalArticle (Academic Journal)

34 Citations (Scopus)

Agreement was moderate between data-based and opinion-based predictions of biases affecting randomized trials within meta-analyses

Turner, R. M., Rhodes, K. M., Jones, H. E., Higgins, J. P. T., Haskins, J., Whiting, P. F., Hróbjartsson, A., Caldwell, D. M., Morris, R. W., Reeves, B. C., Worthington, H., Boutron, I. & Savović, J., 1 Sep 2020, In : Journal of Clinical Epidemiology. 125, p. 16-25 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Allowing for informative missingness in aggregate data meta-analysis with continuous or binary outcomes: Extensions to metamiss

Chaimani, A., Mavridis, D., Higgins, J., Salanti, G. & White, I. R., 14 Sep 2018, In : Stata Journal. 18, 3, p. 716-740 25 p., st0540.

Research output: Contribution to journalArticle (Academic Journal)

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156 Downloads (Pure)

Allowing for uncertainty due to missing continuous outcome data in pairwise and network meta-analysis

Mavridis, D., White, I. R., Higgins, J. P. T., Cipriani, A. & Salanti, G., 13 Nov 2014, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

32 Citations (Scopus)

Altering the availability or proximity of food, alcohol, and tobacco products to change their selection and consumption

Hollands, G. J., Carter, P., Anwer, S., King, S. E., Jebb, S. A., Ogilvie, D., Shemilt, I., Higgins, J. P. T. & Marteau, T. M., 4 Sep 2019, In : Cochrane Database of Systematic Reviews. 9, p. CD012573 96 p.

Research output: Contribution to journalArticle (Academic Journal)

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19 Downloads (Pure)

Altering the availability or proximity of food, alcohol and tobacco products to change their selection and consumption (Protocol)

Hollands, G. J., Carter, P., Shemilt, I., Marteau, T. M., Jebb, S., Higgins, J. & Ogilvie, D., 1 Mar 2017, In : Cochrane Database of Systematic Reviews. 2017, 3, 21 p., CD012573.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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16 Citations (Scopus)
341 Downloads (Pure)

An empirical comparison of heterogeneity variance estimators in 12 894 meta-analyses

Langan, D., Higgins, J. P. T. & Simmonds, M., Jun 2015, In : Research Synthesis Methods. 6, 2, p. 195-205 11 p.

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)

An introduction to methodological issues when including non-randomized studies in systematic reviews on the effects of interventions.

Reeves, B. C., Higgins, J. P. T., Ramsey, C., Tugwell, P. & Wells, G. A., 24 Jan 2013, In : Research Synthesis Methods. 4, 1, p. 1-11

Research output: Contribution to journalArticle (Academic Journal)

Antidepressants might work for people with major depression: where do we go from here?

Cipriani, A., Salanti, G., Furukawa, T. A., Egger, M., Leucht, S., Ruhe, H. G., Turner, E. H., Atkinson, L. Z., Chaimani, A., Higgins, J. P. T., Ogawa, Y., Takeshima, N., Hayasaka, Y., Imai, H., Shinohara, K., Tajika, A., Ioannidis, J. P. A. & Geddes, J. R., 1 Jun 2018, In : Lancet Psychiatry. 5, 6, p. 461-463 3 p.

Research output: Contribution to journalComment/debate (Academic Journal)

8 Citations (Scopus)

Applicability and Feasibility of Systematic Review for Performing Evidence-Based Risk Assessment in Food and Feed Safety

Aiassa, E., Higgins, J. P. T., Frampton, G. K., Greiner, M., Afonso, A., Amzal, B., Deeks, J., Dorne, J. L., Glanville, J., Lövei, G. L., Nienstedt, K., O’connor, A. M., Pullin, A. S., Rajić, A. & Verloo, D., 7 Jun 2015, In : Critical Reviews in Food Science and Nutrition. 55, 7, p. 1026-1034 9 p.

Research output: Contribution to journalArticle (Academic Journal)

21 Citations (Scopus)

A re-evaluation of fixed effect(s) meta-analysis

Rice, K., Higgins, J. P. T. & Lumley, T., 1 Jan 2018, In : Journal of the Royal Statistical Society: Series A. 181, 1, p. 205-227 23 p.

Research output: Contribution to journalArticle (Academic Journal)

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49 Citations (Scopus)
534 Downloads (Pure)

A re-evaluation of random-effects meta-analysis

Higgins, J. P. T., Thompson, SG. & Spiegelhalter, DJ., Jan 2009, In : Journal of the Royal Statistical Society: Series A. 172, 1, p. 137-159 23 p.

Research output: Contribution to journalArticle (Academic Journal)

1001 Citations (Scopus)

Array CGH in patients with learning disability (mental retardation) and congenital anomalies: updated systematic review and meta-analysis of 19 studies and 13,926 subjects

Sagoo, G. S., Butterworth, A. S., Sanderson, S., Shaw-Smith, C., Higgins, J. P. T. & Burton, H., Mar 2009, In : Genetics in Medicine. 11, 3, p. 139-46 8 p.

Research output: Contribution to journalArticle (Academic Journal)

161 Citations (Scopus)
Open Access
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4 Citations (Scopus)
190 Downloads (Pure)

Assessing the impact of drinking water and sanitation on diarrhoeal disease in low- and middle-income settings: systematic review and meta-regression

Wolf, J., Prüss-Ustün, A., Cumming, O., Bartram, J., Bonjour, S., Cairncross, S., Clasen, T., Colford, J. M., Curtis, V., De France, J., Fewtrell, L., Freeman, M. C., Gordon, B., Hunter, P. R., Jeandron, A., Johnston, R. B., Mäusezahl, D., Mathers, C., Neira, M. & Higgins, J. P. T., Aug 2014, In : Tropical Medicine and International Health. 19, 8, p. 928-42 15 p.

Research output: Contribution to journalArticle (Academic Journal)

224 Citations (Scopus)

Assessment of systematic effects of methodological characteristics on candidate genetic associations

Aljasir, B., Ioannidis, J. P. A., Yurkiewich, A., Moher, D., Higgins, J. P. T., Arora, P. & Little, J., 2013, In : Human Genetics. 132, 2, p. 167-78 12 p.

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis

Sterne, J. A. C., Murthy, S., Diaz, J., Slutsky, A. S., Villar, J., Angus, D. C., Annane, D., Azevedo, L. C. P., Berwanger, O., B Cavalcanti, A., Dequin, P-F., Du, B., Emberson, J. R., Fisher, D., Giraudeau, B., Gordon, A. C., Granholm, A., Green, C., Haynes, R., Heming, N. & 18 others, Higgins, J. P. T., Horby, P., Juni, P., Landray, M. J., Le Gouge, A., Leclerc, M., Lim, W. S., R Machado, F., McArthur, C., Meziani, F., Møller, M. H., Perner, A., Petersen, M. W., Savović, J., Tomazini, B., C Veiga, V., Webb, S. & C Marshall, J., 2 Sep 2020, In : JAMA - Journal of the American Medical Association. 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Association between Risk-of-Bias Assessments and Results of Randomized Trials in Cochrane Reviews: The ROBES Meta-Epidemiologic Study

Savović, J., Turner, R. M., Mawdsley, D., Jones, H., Beynon, R., Higgins, J. & Sterne, J., 1 May 2018, In : American Journal of Epidemiology. 187, 5, p. 1113-1122 10 p., kwx344.

Research output: Contribution to journalArticle (Academic Journal)

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97 Citations (Scopus)
275 Downloads (Pure)

Association of BCG, DTP, and measles containing vaccines with childhood mortality: systematic review

Higgins, J., Soares-Weiser, K., Lopez-Lopez, J. A., Kakourou, A., Chaplin, K., Christensen, H., Martin, N., Sterne, J. & Reingold, A. L., 13 Oct 2016, In : BMJ. 355, 13 p., i5170.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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153 Citations (Scopus)
289 Downloads (Pure)

Authors' response to comments from Nachman KE et al.

O'Connor, A. M., Auvermann, B. W., Dzikamunhenga, R. S., Glanville, J. M., Higgins, J. P. T., Kirychuk, S. P., Sargeant, J. M., Totton, S. C., Wood, H. & Von Essen, S. G., 23 Oct 2017, In : Systematic Reviews. 6, 1, 210.

Research output: Contribution to journalComment/debate (Academic Journal)

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179 Downloads (Pure)

Authors' response to letter to the editor

Borenstein, M., Higgins, J. P. T., Hedges, L. V. & Rothstein, H. R., 1 Sep 2017, In : Research Synthesis Methods. 8, 3, 1 p.

Research output: Contribution to journalLetter (Academic Journal)

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243 Downloads (Pure)

Basics of meta-analysis: I2 is not an absolute measure of heterogeneity

Borenstein, M., Higgins, J., Hedges, L. & Rothstein, H., Mar 2017, In : Research Synthesis Methods. 8, 1, p. 5-18 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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332 Citations (Scopus)
1043 Downloads (Pure)

Bayesian multivariate meta-analysis with multiple outcomes

Wei, Y. & Higgins, J. P. T., 2013, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

44 Citations (Scopus)

Between-trial heterogeneity in meta-analyses may be partially explained by reported design characteristics

Rhodes, K. M., Turner, R. M., Savović, J., Jones, H., Mawdsley, D. & Higgins, J., Mar 2018, In : Journal of Clinical Epidemiology. 95, p. 45-54 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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9 Citations (Scopus)
293 Downloads (Pure)

Biases in randomized trials: a conversation between trialists and epidemiologists

Mansournia, M. A., Higgins, J. P. T., Sterne, J. A. C. & Hernán, M. A., 1 Jan 2017, In : Epidemiology. 28, 1, p. 54-59 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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73 Citations (Scopus)
211 Downloads (Pure)

B-type natriuretic peptide-guided therapy for heart failure (HF): a systematic review and meta-analysis of individual participant data (IPD) and aggregate data

Pufulete, M., Maishman, R., Dabner, L., Higgins, J., Rogers, C., Dayer, M., Macleod, J., Purdy, S., Hollingworth, W., Schou, M., Anguita-Sanchez, M., Karlström, P., Kleiner Shochat, M., McDonagh, T., Nightingale, A. & Reeves, B., 31 Jul 2018, In : Systematic Reviews. 7, 21 p., 112.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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11 Citations (Scopus)
297 Downloads (Pure)

Challenges in the use of literature-based meta-analysis to examine gene-environment interactions

Palla, L., Higgins, J. P. T., Wareham, N. J. & Sharp, S. J., 1 Jun 2010, In : American Journal of Epidemiology. 171, 11, p. 1225-32 8 p.

Research output: Contribution to journalArticle (Academic Journal)

36 Citations (Scopus)

Characteristics of a loop of evidence that affect detection and estimation of inconsistency: a simulation study

Veroniki, A. A., Mavridis, D., Higgins, J. P. T. & Salanti, G., 19 Sep 2014, In : BMC Medical Research Methodology. 14, 12 p., 106.

Research output: Contribution to journalArticle (Academic Journal)

28 Citations (Scopus)
6 Downloads (Pure)

Characteristics of meta-analyses and their component studies in the Cochrane Database of Systematic Reviews: a cross-sectional, descriptive analysis

Davey, J., Turner, R. M., Clarke, M. J. & Higgins, J. P. T., 2011, In : BMC Medical Research Methodology. 11, p. 160

Research output: Contribution to journalArticle (Academic Journal)

181 Citations (Scopus)

Checklists of methodological issues for review authors to consider when including non-randomized studies in systematic reviews.

Wells, G. A., Shea, B., Higgins, J. P. T., Sterne, J. A. C., Tugwell, P. & Reeves, B. C., Mar 2013, In : Research Synthesis Methods. 4, 1, p. 63-77

Research output: Contribution to journalArticle (Academic Journal)

Choice of implant combinations in total hip replacement: systematic review and network meta-analysis

Lopez-Lopez, J. A., Humphriss, R., Beswick, A., Thom, H., Hunt, L., Burston, A., Fawsitt, C., Hollingworth, W., Higgins, J., Welton, N., Blom, A. & Marques, E., 2 Nov 2017, In : BMJ. 359, 9 p., j4651.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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22 Citations (Scopus)
314 Downloads (Pure)

CINeMA: An approach for assessing confidence in the results of a network meta-analysis

Nikolakopoulou, A., Higgins, J. P. T., Papakonstantinou, T., Chaimani, A., Del Giovane, C., Egger, M. & Salanti, G., 3 Apr 2020, In : PLoS Medicine. 17, 4, 19 p., e1003082.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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35 Downloads (Pure)

CINeMA: Software for semi-automated assessment of the Confidence In the results of Network Meta-Analysis

Papakonstantinou, T., Nikolakopoulou, A., Higgins, J. P. T., Egger, M. & Salanti, G., Mar 2020, In : Campbell Systematic Reviews. 15 p., e1080.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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43 Downloads (Pure)

Cognitive-behavioural interventions for children who have been sexually abused

Macdonald, G., Higgins, J. P. T., Ramchandani, P., Valentine, J. C., Bronger, L. P., Klein, P., O'Daniel, R., Pickering, M., Rademaker, B., Richardson, G. & Taylor, M., 2012, In : Cochrane Database of Systematic Reviews. 5, p. CD001930

Research output: Contribution to journalArticle (Academic Journal)

44 Citations (Scopus)

Comments on 'Empirical vs natural weighting in random effects meta-analysis'

Thompson, S. G. & Higgins, J. P. T., 30 May 2010, In : Statistics in Medicine. 29, 12, p. 1270-1; discussion 1272-81

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)

Comparative efficacy and acceptability of 12 new-generation antidepressants: A multiple-treatments meta-analysis

Cipriani, A., Furukawa, T. A., Salanti, G., Geddes, J. R., Higgins, J. P. T., Churchill, R. C., Watanabe, N., Nakagawa, A., Omori, I. M., McGuire, H., Tansella, M. & Barbui, C., 28 Feb 2009, In : Lancet. 373, 9665, p. 746 - 758 12 p.

Research output: Contribution to journalArticle (Academic Journal)

1154 Citations (Scopus)

Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis

Cipriani, A., Furukawa, T. A., Salanti, G., Chaimani, A., Atkinson, L. Z., Ogawa, Y., Leucht, S., Ruhe, H. G., Turner, E. H., Higgins, J., Egger, M., Takeshima, N., Hayasaka, Y., Imai, H., Shinohara, K., Tajika, A., Ioannidis, J. PA. & Geddes, J. R., 7 Apr 2018, In : Lancet. 391, 10128, p. 1357-1366 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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606 Citations (Scopus)
569 Downloads (Pure)

Comparative efficacy and safety of treatments for localised prostate cancer an application of network meta-analysis

Xiong, T., Turner, R. M., Wei, Y., Neal, D. E., Lyratzopoulos, G. & Higgins, J. P. T., 15 May 2014, In : BMJ Open. 4, 5, p. e004285

Research output: Contribution to journalArticle (Academic Journal)

29 Citations (Scopus)

Comparative performance of heterogeneity variance estimators in meta-analysis: A review of simulation studies

Langan, D., Higgins, J. P. T. & Simmonds, M., Jun 2017, In : Research Synthesis Methods. 8, 2, p. 181–198 18 p.

Research output: Contribution to journalArticle (Academic Journal)

34 Citations (Scopus)

Conceptual and technical challenges in network meta-analysis

Cipriani, A., Higgins, J. P. T., Geddes, J. R. & Salanti, G., 16 Jul 2013, In : Annals of Internal Medicine. 159, 2, p. 130-7 8 p.

Research output: Contribution to journalArticle (Academic Journal)

398 Citations (Scopus)