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Research Output

2017

Basics of meta-analysis: I2 is not an absolute measure of heterogeneity

Borenstein, M., Higgins, J., Hedges, L. & Rothstein, H., Mar 2017, In : Research Synthesis Methods. 8, 1, p. 5-18 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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332 Citations (Scopus)
1043 Downloads (Pure)

Biases in randomized trials: a conversation between trialists and epidemiologists

Mansournia, M. A., Higgins, J. P. T., Sterne, J. A. C. & Hernán, M. A., 1 Jan 2017, In : Epidemiology. 28, 1, p. 54-59 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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73 Citations (Scopus)
211 Downloads (Pure)

Choice of implant combinations in total hip replacement: systematic review and network meta-analysis

Lopez-Lopez, J. A., Humphriss, R., Beswick, A., Thom, H., Hunt, L., Burston, A., Fawsitt, C., Hollingworth, W., Higgins, J., Welton, N., Blom, A. & Marques, E., 2 Nov 2017, In : BMJ. 359, 9 p., j4651.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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22 Citations (Scopus)
314 Downloads (Pure)

Comparative performance of heterogeneity variance estimators in meta-analysis: A review of simulation studies

Langan, D., Higgins, J. P. T. & Simmonds, M., Jun 2017, In : Research Synthesis Methods. 8, 2, p. 181–198 18 p.

Research output: Contribution to journalArticle (Academic Journal)

34 Citations (Scopus)

Control of carbapenemase-producing Enterobacteriaceae outbreaks in acute settings: an evidence review Journal of Hospital Infection

French, C., Coope, C., Conway, L., Higgins, J., McCulloch, J., Okoli, G., Patel, B. C. & Oliver, I., 2 Jan 2017, In : Journal of Hospital Infection. 95, 1, p. 3-45 42 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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30 Citations (Scopus)
303 Downloads (Pure)

Corticosteroids in septic shock: a systematic review and network meta-analysis

Gibbison, B., Lopez-Lopez, J. A., Higgins, J., Miller, T., Angelini, G., Lightman, S. & Annane, D., 28 Mar 2017, In : Critical Care. 21, 1, 3 p., 78.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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45 Citations (Scopus)
336 Downloads (Pure)

Developing the WCRF International/University of Bristol methodology for identifying and carrying out systematic reviews of mechanisms of exposure-cancer associations

Lewis, S., Gardner, M., Higgins, J., Holly, J. M. P., Gaunt, T., Perks, C., Turner, S., Rinaldi, S., Thomas, S., Harrison, S., Lennon, R., Tan, V., Borwick, C., Emmett, P., Jeffreys, M., Northstone, K., Mitrou, G., Wiseman, M., Thompson, R. & Martin, R., 4 Oct 2017, In : Cancer Epidemiology, Biomarkers and Prevention. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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6 Citations (Scopus)
226 Downloads (Pure)

Does milk intake promote prostate cancer initiation or progression via effects on insulin-like growth factors (IGFs)? A systematic review and meta-analysis

Harrison, S., Lennon, R., Holly, J. M. P., Higgins, J., Gardner, M. P., Perks, C., Gaunt, T., Tan, V., Borwick, C., Emmett, P., Jeffreys, M., Northstone, K., Rinaldi, S., Thomas, S., Turner, S., Pease, A., Vilenchik, V., Martin, R. & Lewis, S., Jun 2017, In : Cancer Causes and Control. 28, 6, p. 497–528 32 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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25 Citations (Scopus)
419 Downloads (Pure)
Open Access
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10 Citations (Scopus)
323 Downloads (Pure)

Heterogeneity in application, design and analysis characteristics was found for controlled before-after (CBA) and interrupted time series (ITS) studies included in Cochrane reviews

Polus, S., Pieper, D., Burns, J., Fretheim, A., Ramsay, C., Higgins, J. PT., Mathes, T., Pfadenhauer, L. M. & Rehfuess, E. A., 25 Jul 2017, In : Journal of Clinical Epidemiology.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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12 Citations (Scopus)
330 Downloads (Pure)

Indirect evidence of reporting biases was found in a survey of medical research studies

Albarqouni, L. N., López-López, J. A. & Higgins, J. PT., Mar 2017, In : Journal of Clinical Epidemiology. 83, p. 57-64 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
209 Downloads (Pure)

Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis

López-López, J. A., Sterne, J. A. C., Thom, H. H. Z., Higgins, J. P. T., Hingorani, A. D., Okoli, G. N., Davies, P. A., Bodalia, P. N., Bryden, P. A., Welton, N. J., Hollingworth, W., Caldwell, D. M., Savović, J., Dias, S., Salisbury, C., Eaton, D., Stephens-Boal, A. & Sofat, R., 28 Nov 2017, In : BMJ. 359, j5058.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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140 Citations (Scopus)
351 Downloads (Pure)
Open Access
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64 Citations (Scopus)
332 Downloads (Pure)

Screening strategies for atrial fibrillation: A systematic review and cost-effectiveness analysis

Welton, N. J., McAleenan, A., Thom, H. H. Z., Davies, P., Hollingworth, W., Higgins, J. P. T., Okoli, G., Sterne, J. A. C., Feder, G., Eaton, D., Hingorani, A., Fawsitt, C., Lobban, T., Bryden, P., Richards, A. & Sofat, R., 1 May 2017, In : Health Technology Assessment. 21, 29, p. vii-235 272 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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47 Citations (Scopus)
644 Downloads (Pure)

The albatross plot: A novel graphical tool for presenting results of diversely reported studies in a systematic review

Harrison, S., Jones, H., Martin, R., Lewis, S. & Higgins, J., 1 Sep 2017, In : Research Synthesis Methods. 8, 3, p. 281-289 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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23 Citations (Scopus)
302 Downloads (Pure)

The INVEST project: investigating the use of evidence synthesis in the design and analysis of clinical trials

Clayton, G., Smith, I. L., Higgins, J., Mihaylova, B., Thorpe, B., Cicero, R., Lokuge, K., Forman, J. R., Tierney, J. F., White, I. R., Sharples, L. & Jones, H., 15 May 2017, In : Trials. 18, 219, 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
272 Downloads (Pure)

Therapeutic interventions for alcohol dependence in non-inpatient settings: a systematic review and network meta-analysis (protocol)

Cheng, H-Y., Elbers, R. G., Higgins, J. P. T., Taylor, A., MacArthur, G. J., McGuinness, L., Dawson, S., López-López, J. A., Cowlishaw, S., Hickman, M. & Kessler, D., 11 Apr 2017, In : Systematic Reviews. 6, 1, p. 77

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
271 Downloads (Pure)

Updated systematic review: Associations between proximity to animal feeding operations and health of individuals in nearby communities

O'Connor, A. M., Auvermann, B. W., Dzikamunhenga, R. S., Glanville, J. M., Higgins, J. P. T., Kirychuk, S. P., Sargeant, J. M., Totton, S. C., Wood, H. & Von Essen, S. G., 18 Apr 2017, In : Systematic Reviews. 6, 1, 86.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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13 Citations (Scopus)
250 Downloads (Pure)
2016

Association of BCG, DTP, and measles containing vaccines with childhood mortality: systematic review

Higgins, J., Soares-Weiser, K., Lopez-Lopez, J. A., Kakourou, A., Chaplin, K., Christensen, H., Martin, N., Sterne, J. & Reingold, A. L., 13 Oct 2016, In : BMJ. 355, 13 p., i5170.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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153 Citations (Scopus)
289 Downloads (Pure)

Empirical evidence of study design biases in randomized trials: systematic review of meta-epidemiological studies

Page, M. J., Higgins, J. P. T., Clayton, G. L., Sterne, J. A. C., Hrobjartsson, A. & Savovic, J., 11 Jul 2016, In : PLoS ONE. 11, 7, 26 p., e0159267.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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73 Citations (Scopus)
302 Downloads (Pure)

Evaluation of the Cochrane tool for assessing risk of bias in randomized clinical trials: Overview of published comments and analysis of user practice in Cochrane and non-Cochrane reviews

Jørgensen, L., Paludan-Müller, A., Laursen, D., Savovic, J., Boutron, I., Sterne, J., Higgins, J. & Hróbjartsson, A., 10 May 2016, In : Systematic Reviews. 5, p. 1-13 13 p., 80.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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74 Citations (Scopus)
290 Downloads (Pure)

Extending DerSimonian and Laird's methodology to perform network meta-analyses with random inconsistency effects

Jackson, D., Law, M., Barrett, J. K., Turner, R., Higgins, J. P., Salanti, G. & White, I. R., 15 Mar 2016, In : Statistics in Medicine. 35, 6, p. 819-839 21 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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193 Downloads (Pure)

Implementing informative priors for heterogeneity in meta-analysis using meta-regression and pseudo data

Rhodes, K. M., Turner, R. M., White, I. R., Jackson, D., Spiegelhalter, D. & Higgins, J. P. T., 20 Dec 2016, In : Statistics in Medicine. 35, 29, p. 5495-5511 17 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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14 Citations (Scopus)
413 Downloads (Pure)

Machine learning to assist risk of bias assessments in systematic reviews

Millard, L. A. C., Flach, P. A. & Higgins, J. P. T., 1 Feb 2016, In : International Journal of Epidemiology. 45, 1, p. 266-277 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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14 Citations (Scopus)
303 Downloads (Pure)

Methods to estimate the between-study variance and its uncertainty in meta-analysis

Veroniki, A. A., Jackson, D., Viechtbauer, W., Bender, R., Bowden, J., Knapp, G., Kuss, O., Higgins, J. P. T., Langan, D. & Salanti, G., 1 Mar 2016, In : Research Synthesis Methods. 7, 1, p. 55-79 25 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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244 Citations (Scopus)
593 Downloads (Pure)

Rethinking the assessment of risk of bias due to selective reporting: a cross-sectional study

Page, M. J. & Higgins, J. PT., 8 Jul 2016, In : Systematic Reviews. 5, 8 p., 108.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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15 Citations (Scopus)
301 Downloads (Pure)

Risk of nosocomial respiratory syncytial virus infection and effectiveness of control measures to prevent transmission events: a systematic review

French, C. E., McKenzie, B., Coope, C. M., Rajanaidu, S., Paranthaman, K., Pebody, R., Nguyen-Van-Tam, J., Higgins, J. P. T. & Beck, C. R., Jul 2016, In : Influenza and Other Respiratory Viruses. 10, 4, p. 268-290 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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35 Citations (Scopus)
288 Downloads (Pure)

ROBINS-I: a tool for assessing risk of bias in non-randomized studies of interventions

Sterne, J., Hernán, M. A., Reeves, B., Savović, J., Berkman, N. D., Viswanathan, M., Henry, D., Altman, D. G., Ansari, M. T., Boutron, I., Carpenter, J. R., Chan, A-W., Churchill, R., Deeks, J. J., Hróbjartsson, A., Kirkham, J., Juni, P., Loke, Y. K., Pigott, T. D., Ramsay, C. R. & 14 others, Regidor, D., Rothstein, H. R., Sandhu, L., Schünemann, H., Shea, B., Shrier, I., Tugwell, P., Turner, L., Valentine, J. C., Waddington, H., Waters, E., Wells, G. A., Whiting, P. & Higgins, J., 12 Oct 2016, In : BMJ. 355, 7 p., i4919.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1816 Citations (Scopus)
440 Downloads (Pure)

ROBIS: A new tool to assess risk of bias in systematic reviews was developed

Whiting, P. F., Savovic, J., Higgins, J. P. T., Caldwell, D. M., Reeves, B. C., Shea, B., Davies, P., Kleijnen, J., Churchill, R. C. & ROBIS Group, Jan 2016, In : Journal of Clinical Epidemiology. 69, p. 225-324 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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347 Citations (Scopus)
744 Downloads (Pure)

Systematic review with meta-analysis: the gastrointestinal benefits of COX-2 selective inhibitors with concomitant use of low-dose aspirin

Yuan, J., Yang, M., Threapleton, D. E., Qi, X. S., Ye, D. Q., Mao, C., Tang, J. L. & Higgins, J. P. T., Oct 2016, In : Alimentary Pharmacology and Therapeutics. 44, 8, p. 785–795 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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5 Citations (Scopus)
426 Downloads (Pure)
Open Access
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7 Citations (Scopus)
388 Downloads (Pure)
Open Access
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2 Citations (Scopus)
233 Downloads (Pure)
Open Access
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1 Citation (Scopus)
240 Downloads (Pure)
2015

A Cost-Effectiveness Analysis Of Novel Oral Anticoagulants For Acute Treatment And Secondary Prevention Of Venous Thromboembolic Disease

Bryden, P., Welton, N. J., Thom, H., Sterne, J., Bodalia, P., Davies, P., López-López, J., Okoli, G. N., Caldwell, D. M., Dias, S., Eaton, D., Higgins, J., Salisbury, C., Savovic, J., Sofat, R., Stephens-Boal, A., Hingorani, A. & Hollingworth, W., Nov 2015, In : Value in Health. 18, 7, p. A390

Research output: Contribution to journalArticle (Academic Journal)

A Cost-Effectiveness Analysis of Novel Oral Anticoagulants for Primary Prevention of Venous Thromboembolic Disease

Bryden, P., Welton, N. J., Thom, H., Sterne, J., Bodalia, P., Davies, P., López-López, J., Okoli, G. N., Caldwell, D. M., Dias, S., Eaton, D., Higgins, J., Salisbury, C., Savovic, J., Sofat, R., Stephens-Boal, A., Hingorani, A. & Hollingworth, W., Nov 2015, In : Value in Health. 18, 7, p. A339-40

Research output: Contribution to journalArticle (Academic Journal)

Adjuvant chemotherapy for resected early-stage non-small cell lung cancer

Burdett, S., Pignon, J. P., Tierney, J., Tribodet, H., Stewart, L., Le Pechoux, C., Aupérin, A., Le Chevalier, T., Stephens, R. J., Arriagada, R., Higgins, J. P., Johnson, D. H., Van Meerbeeck, J., Parmar, M. K., Souhami, R. L., Bergman, B., Douillard, J-Y., Dunant, A., Endo, C., Girling, D. & 21 others, Kato, H., Keller, S. M., Kimura, H., Knuuttila, A., Kodama, K., Komaki, R., Kris, M. G., Lad, T., Mineo, T., Piantadosi, S., Rosell, R., Scagliotti, G., Seymour, L. K., Shepherd, F. A., Sylvester, R., Tada, H., Tanaka, F., Torri, V., Waller, D., Liang, Y. & for the Non‐Small Cell Lung Cancer Collaborative Group, 2 Mar 2015, In : Cochrane Database of Systematic Reviews. 3, p. CD011430

Research output: Contribution to journalArticle (Academic Journal)

103 Citations (Scopus)

An empirical comparison of heterogeneity variance estimators in 12 894 meta-analyses

Langan, D., Higgins, J. P. T. & Simmonds, M., Jun 2015, In : Research Synthesis Methods. 6, 2, p. 195-205 11 p.

Research output: Contribution to journalArticle (Academic Journal)

20 Citations (Scopus)

Applicability and Feasibility of Systematic Review for Performing Evidence-Based Risk Assessment in Food and Feed Safety

Aiassa, E., Higgins, J. P. T., Frampton, G. K., Greiner, M., Afonso, A., Amzal, B., Deeks, J., Dorne, J. L., Glanville, J., Lövei, G. L., Nienstedt, K., O’connor, A. M., Pullin, A. S., Rajić, A. & Verloo, D., 7 Jun 2015, In : Critical Reviews in Food Science and Nutrition. 55, 7, p. 1026-1034 9 p.

Research output: Contribution to journalArticle (Academic Journal)

21 Citations (Scopus)

Empirical evidence about inconsistency among studies in a pair-wise meta-analysis

Rhodes, K. M., Turner, R. M. & Higgins, J. P. T., 17 Dec 2015, In : Research Synthesis Methods.

Research output: Contribution to journalArticle (Academic Journal)

14 Citations (Scopus)

Network meta-analysis: A norm for comparative effectiveness?

Higgins, J. P. T. & Welton, N. J., 15 Aug 2015, In : Lancet. 386, 9994, p. 628-630 3 p.

Research output: Contribution to journalComment/debate (Academic Journal)

Open Access
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29 Citations (Scopus)
461 Downloads (Pure)

Network Meta-Analysis of Oral Anticoagulants for Primary Prevention, Treatment and Secondary Prevention of Venous Thromboembolic Disease, and for Prevention of Stroke in Atrial Fibrillation

Lopez-Lopez, J. A., Sterne, J., Bodalia, P. N., Bryden, P. A., Davies, P., Okoli, G. N., Thom, H., Caldwell, D. M., Dias, S., Eaton, D., Higgins, J., Hollingworth, W., Salisbury, C., Savovic, J., Sofat, R., Stephens-Boal, A., Welton, N. J. & Hingorani, A., Nov 2015, In : Value in Health. 18, 7, p. A374

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)

Personal financial incentives for changing habitual health-related behaviors: A systematic review and meta-analysis

Mantzari, E., Vogt, F., Shemilt, I., Wei, Y., Higgins, J. P. T. & Marteau, T. M., 12 Mar 2015, In : Preventive Medicine.

Research output: Contribution to journalArticle (Academic Journal)

106 Citations (Scopus)

Portion, package or tableware size for changing selection and consumption of food, alcohol and tobacco

Hollands, G. J., Shemilt, I., Marteau, T. M., Jebb, S. A., Lewis, H. B., Wei, Y., Higgins, J. P. & Ogilvie, D., 14 Sep 2015, In : Cochrane Database of Systematic Reviews. 9, p. CD011045

Research output: Contribution to journalArticle (Academic Journal)

79 Citations (Scopus)

Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation

Shamseer, L., Moher, D., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P., Stewart, L. A. & PRISMA-P Group, 2 Jan 2015, In : BMJ. 349, 25 p., g7647.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1031 Downloads (Pure)

Risk of neuropsychiatric adverse events associated with varenicline: systematic review and meta-analysis

Thomas, K. H., Martin, R. M., Knipe, D. W., Higgins, J. P. T. & Gunnell, D., 12 Mar 2015, In : BMJ. 350, 11 p., h1109.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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73 Citations (Scopus)
278 Downloads (Pure)

Sample size calculation for meta-epidemiological studies

Giraudeau, B., Higgins, J. P. T., Tavernier, E. & Trinquart, L., 19 Aug 2015, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

18 Citations (Scopus)

Summarising and validating test accuracy results across multiple studies for use in clinical practice

Riley, R. D., Ahmed, I., Debray, T. P. A., Willis, B. H., Noordzij, J. P., Higgins, J. P. T. & Deeks, J. J., 20 Mar 2015, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

22 Citations (Scopus)

The Cost-Effectiveness Of Novel Oral Anticoagulants For The Prevention Of Stroke In Atrial Fibrillation In England And Wales

Thom, H., Hollingworth, W., Bryden, P. A., Sterne, J., Bodalia, P. N., Davies, P., Lopez-Lopez, J. A., Okoli, G. N., Caldwell, D. M., Dias, S., Eaton, D., Higgins, J., Salisbury, C., Savovic, J., Sofat, R., Stephens-Boal, A., Hingorani, A. & Welton, N. J., Nov 2015, In : Value in Health. 18, 7, p. A391-2

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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212 Citations (Scopus)
408 Downloads (Pure)

The use of Bayesian networks to assess the quality of evidence from research synthesis: 1

Stewart, G. B., Higgins, J. P. T., Schünemann, H. & Meader, N., 2015, In : PLoS ONE. 10, 3, p. e0114497

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)