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Research Output

2016

ROBIS: A new tool to assess risk of bias in systematic reviews was developed

Whiting, P. F., Savovic, J., Higgins, J. P. T., Caldwell, D. M., Reeves, B. C., Shea, B., Davies, P., Kleijnen, J., Churchill, R. C. & ROBIS Group, Jan 2016, In : Journal of Clinical Epidemiology. 69, p. 225-324 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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356 Citations (Scopus)
754 Downloads (Pure)

Systematic review with meta-analysis: the gastrointestinal benefits of COX-2 selective inhibitors with concomitant use of low-dose aspirin

Yuan, J., Yang, M., Threapleton, D. E., Qi, X. S., Ye, D. Q., Mao, C., Tang, J. L. & Higgins, J. P. T., Oct 2016, In : Alimentary Pharmacology and Therapeutics. 44, 8, p. 785–795 11 p.

Research output: Contribution to journalArticle (Academic Journal)

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5 Citations (Scopus)
440 Downloads (Pure)
Open Access
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7 Citations (Scopus)
395 Downloads (Pure)
Open Access
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2 Citations (Scopus)
238 Downloads (Pure)
Open Access
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1 Citation (Scopus)
244 Downloads (Pure)
2017

Accounting for heterogeneity in meta-analysis using a multiplicative model—an empirical study

Mawdsley, D., Higgins, J., Sutton, A. J. & Abrams, K., Mar 2017, In : Research Synthesis Methods. 8, 1, p. 43–52 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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6 Citations (Scopus)
259 Downloads (Pure)

Additional considerations are required when preparing a protocol for a systematic review with multiple interventions

Chaimani, A., Caldwell, D., Li, T., Higgins, J. & Salanti, G., Mar 2017, In : Journal of Clinical Epidemiology. 83, p. 65–74 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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39 Citations (Scopus)
366 Downloads (Pure)

Altering the availability or proximity of food, alcohol and tobacco products to change their selection and consumption (Protocol)

Hollands, G. J., Carter, P., Shemilt, I., Marteau, T. M., Jebb, S., Higgins, J. & Ogilvie, D., 1 Mar 2017, In : Cochrane Database of Systematic Reviews. 2017, 3, 21 p., CD012573.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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19 Citations (Scopus)
350 Downloads (Pure)

Authors' response to comments from Nachman KE et al.

O'Connor, A. M., Auvermann, B. W., Dzikamunhenga, R. S., Glanville, J. M., Higgins, J. P. T., Kirychuk, S. P., Sargeant, J. M., Totton, S. C., Wood, H. & Von Essen, S. G., 23 Oct 2017, In : Systematic Reviews. 6, 1, 210.

Research output: Contribution to journalComment/debate (Academic Journal)

Open Access
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182 Downloads (Pure)

Authors' response to letter to the editor

Borenstein, M., Higgins, J. P. T., Hedges, L. V. & Rothstein, H. R., 1 Sep 2017, In : Research Synthesis Methods. 8, 3, 1 p.

Research output: Contribution to journalLetter (Academic Journal)

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245 Downloads (Pure)

Basics of meta-analysis: I2 is not an absolute measure of heterogeneity

Borenstein, M., Higgins, J., Hedges, L. & Rothstein, H., Mar 2017, In : Research Synthesis Methods. 8, 1, p. 5-18 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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342 Citations (Scopus)
1060 Downloads (Pure)

Biases in randomized trials: a conversation between trialists and epidemiologists

Mansournia, M. A., Higgins, J. P. T., Sterne, J. A. C. & Hernán, M. A., 1 Jan 2017, In : Epidemiology. 28, 1, p. 54-59 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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74 Citations (Scopus)
218 Downloads (Pure)

Choice of implant combinations in total hip replacement: systematic review and network meta-analysis

Lopez-Lopez, J. A., Humphriss, R., Beswick, A., Thom, H., Hunt, L., Burston, A., Fawsitt, C., Hollingworth, W., Higgins, J., Welton, N., Blom, A. & Marques, E., 2 Nov 2017, In : BMJ. 359, 9 p., j4651.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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22 Citations (Scopus)
319 Downloads (Pure)

Comparative performance of heterogeneity variance estimators in meta-analysis: A review of simulation studies

Langan, D., Higgins, J. P. T. & Simmonds, M., Jun 2017, In : Research Synthesis Methods. 8, 2, p. 181–198 18 p.

Research output: Contribution to journalArticle (Academic Journal)

35 Citations (Scopus)

Control of carbapenemase-producing Enterobacteriaceae outbreaks in acute settings: an evidence review Journal of Hospital Infection

French, C., Coope, C., Conway, L., Higgins, J., McCulloch, J., Okoli, G., Patel, B. C. & Oliver, I., 2 Jan 2017, In : Journal of Hospital Infection. 95, 1, p. 3-45 42 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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30 Citations (Scopus)
309 Downloads (Pure)

Corticosteroids in septic shock: a systematic review and network meta-analysis

Gibbison, B., Lopez-Lopez, J. A., Higgins, J., Miller, T., Angelini, G., Lightman, S. & Annane, D., 28 Mar 2017, In : Critical Care. 21, 1, 3 p., 78.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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45 Citations (Scopus)
339 Downloads (Pure)

Developing the WCRF International/University of Bristol methodology for identifying and carrying out systematic reviews of mechanisms of exposure-cancer associations

Lewis, S., Gardner, M., Higgins, J., Holly, J. M. P., Gaunt, T., Perks, C., Turner, S., Rinaldi, S., Thomas, S., Harrison, S., Lennon, R., Tan, V., Borwick, C., Emmett, P., Jeffreys, M., Northstone, K., Mitrou, G., Wiseman, M., Thompson, R. & Martin, R., 4 Oct 2017, In : Cancer Epidemiology, Biomarkers and Prevention. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

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6 Citations (Scopus)
234 Downloads (Pure)

Does milk intake promote prostate cancer initiation or progression via effects on insulin-like growth factors (IGFs)? A systematic review and meta-analysis

Harrison, S., Lennon, R., Holly, J. M. P., Higgins, J., Gardner, M. P., Perks, C., Gaunt, T., Tan, V., Borwick, C., Emmett, P., Jeffreys, M., Northstone, K., Rinaldi, S., Thomas, S., Turner, S., Pease, A., Vilenchik, V., Martin, R. & Lewis, S., Jun 2017, In : Cancer Causes and Control. 28, 6, p. 497–528 32 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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25 Citations (Scopus)
436 Downloads (Pure)
Open Access
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10 Citations (Scopus)
330 Downloads (Pure)

Heterogeneity in application, design and analysis characteristics was found for controlled before-after (CBA) and interrupted time series (ITS) studies included in Cochrane reviews

Polus, S., Pieper, D., Burns, J., Fretheim, A., Ramsay, C., Higgins, J. PT., Mathes, T., Pfadenhauer, L. M. & Rehfuess, E. A., 25 Jul 2017, In : Journal of Clinical Epidemiology.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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13 Citations (Scopus)
345 Downloads (Pure)

Indirect evidence of reporting biases was found in a survey of medical research studies

Albarqouni, L. N., López-López, J. A. & Higgins, J. PT., Mar 2017, In : Journal of Clinical Epidemiology. 83, p. 57-64 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
212 Downloads (Pure)

Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis

López-López, J. A., Sterne, J. A. C., Thom, H. H. Z., Higgins, J. P. T., Hingorani, A. D., Okoli, G. N., Davies, P. A., Bodalia, P. N., Bryden, P. A., Welton, N. J., Hollingworth, W., Caldwell, D. M., Savović, J., Dias, S., Salisbury, C., Eaton, D., Stephens-Boal, A. & Sofat, R., 28 Nov 2017, In : BMJ. 359, j5058.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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142 Citations (Scopus)
359 Downloads (Pure)
Open Access
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65 Citations (Scopus)
346 Downloads (Pure)

Screening strategies for atrial fibrillation: A systematic review and cost-effectiveness analysis

Welton, N. J., McAleenan, A., Thom, H. H. Z., Davies, P., Hollingworth, W., Higgins, J. P. T., Okoli, G., Sterne, J. A. C., Feder, G., Eaton, D., Hingorani, A., Fawsitt, C., Lobban, T., Bryden, P., Richards, A. & Sofat, R., 1 May 2017, In : Health Technology Assessment. 21, 29, p. vii-235 272 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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48 Citations (Scopus)
658 Downloads (Pure)

The albatross plot: A novel graphical tool for presenting results of diversely reported studies in a systematic review

Harrison, S., Jones, H., Martin, R., Lewis, S. & Higgins, J., 1 Sep 2017, In : Research Synthesis Methods. 8, 3, p. 281-289 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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25 Citations (Scopus)
311 Downloads (Pure)

The INVEST project: investigating the use of evidence synthesis in the design and analysis of clinical trials

Clayton, G., Smith, I. L., Higgins, J., Mihaylova, B., Thorpe, B., Cicero, R., Lokuge, K., Forman, J. R., Tierney, J. F., White, I. R., Sharples, L. & Jones, H., 15 May 2017, In : Trials. 18, 219, 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
278 Downloads (Pure)

Therapeutic interventions for alcohol dependence in non-inpatient settings: a systematic review and network meta-analysis (protocol)

Cheng, H-Y., Elbers, R. G., Higgins, J. P. T., Taylor, A., MacArthur, G. J., McGuinness, L., Dawson, S., López-López, J. A., Cowlishaw, S., Hickman, M. & Kessler, D., 11 Apr 2017, In : Systematic Reviews. 6, 1, p. 77

Research output: Contribution to journalArticle (Academic Journal)

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4 Citations (Scopus)
273 Downloads (Pure)

Updated systematic review: Associations between proximity to animal feeding operations and health of individuals in nearby communities

O'Connor, A. M., Auvermann, B. W., Dzikamunhenga, R. S., Glanville, J. M., Higgins, J. P. T., Kirychuk, S. P., Sargeant, J. M., Totton, S. C., Wood, H. & Von Essen, S. G., 18 Apr 2017, In : Systematic Reviews. 6, 1, 86.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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13 Citations (Scopus)
251 Downloads (Pure)
2018

A comparison of heterogeneity variance estimators in simulated random-effects meta-analyses

Langan, D., Higgins, J. P. T., Jackson, D., Bowden, J., Veroniki, A. A., Kontopantelis, E., Viechtbauer, W. & Simmonds, M., 6 Sep 2018, In : Research Synthesis Methods. 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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44 Citations (Scopus)
143 Downloads (Pure)

Allowing for informative missingness in aggregate data meta-analysis with continuous or binary outcomes: Extensions to metamiss

Chaimani, A., Mavridis, D., Higgins, J., Salanti, G. & White, I. R., 14 Sep 2018, In : Stata Journal. 18, 3, p. 716-740 25 p., st0540.

Research output: Contribution to journalArticle (Academic Journal)

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160 Downloads (Pure)

Antidepressants might work for people with major depression: where do we go from here?

Cipriani, A., Salanti, G., Furukawa, T. A., Egger, M., Leucht, S., Ruhe, H. G., Turner, E. H., Atkinson, L. Z., Chaimani, A., Higgins, J. P. T., Ogawa, Y., Takeshima, N., Hayasaka, Y., Imai, H., Shinohara, K., Tajika, A., Ioannidis, J. P. A. & Geddes, J. R., 1 Jun 2018, In : Lancet Psychiatry. 5, 6, p. 461-463 3 p.

Research output: Contribution to journalComment/debate (Academic Journal)

8 Citations (Scopus)

A re-evaluation of fixed effect(s) meta-analysis

Rice, K., Higgins, J. P. T. & Lumley, T., 1 Jan 2018, In : Journal of the Royal Statistical Society: Series A. 181, 1, p. 205-227 23 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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49 Citations (Scopus)
556 Downloads (Pure)
Open Access
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4 Citations (Scopus)
194 Downloads (Pure)

Association between Risk-of-Bias Assessments and Results of Randomized Trials in Cochrane Reviews: The ROBES Meta-Epidemiologic Study

Savović, J., Turner, R. M., Mawdsley, D., Jones, H., Beynon, R., Higgins, J. & Sterne, J., 1 May 2018, In : American Journal of Epidemiology. 187, 5, p. 1113-1122 10 p., kwx344.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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101 Citations (Scopus)
277 Downloads (Pure)

Between-trial heterogeneity in meta-analyses may be partially explained by reported design characteristics

Rhodes, K. M., Turner, R. M., Savović, J., Jones, H., Mawdsley, D. & Higgins, J., Mar 2018, In : Journal of Clinical Epidemiology. 95, p. 45-54 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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9 Citations (Scopus)
297 Downloads (Pure)

B-type natriuretic peptide-guided therapy for heart failure (HF): a systematic review and meta-analysis of individual participant data (IPD) and aggregate data

Pufulete, M., Maishman, R., Dabner, L., Higgins, J., Rogers, C., Dayer, M., Macleod, J., Purdy, S., Hollingworth, W., Schou, M., Anguita-Sanchez, M., Karlström, P., Kleiner Shochat, M., McDonagh, T., Nightingale, A. & Reeves, B., 31 Jul 2018, In : Systematic Reviews. 7, 21 p., 112.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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11 Citations (Scopus)
298 Downloads (Pure)

Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis

Cipriani, A., Furukawa, T. A., Salanti, G., Chaimani, A., Atkinson, L. Z., Ogawa, Y., Leucht, S., Ruhe, H. G., Turner, E. H., Higgins, J., Egger, M., Takeshima, N., Hayasaka, Y., Imai, H., Shinohara, K., Tajika, A., Ioannidis, J. PA. & Geddes, J. R., 7 Apr 2018, In : Lancet. 391, 10128, p. 1357-1366 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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623 Citations (Scopus)
578 Downloads (Pure)

Dealing with effect size multiplicity in systematic reviews and meta-analyses

Lopez-Lopez, J. A., Page, M., Lipsey, M. & Higgins, J., Sep 2018, In : Research Synthesis Methods. 9, 3, p. 336-351 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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10 Citations (Scopus)
264 Downloads (Pure)

Doug Altman's legacy to Cochrane and evidence synthesis

Deeks, J. J., Hopewell, S., Moher, D., Higgins, J., Moons, K. G. M., Chandler, J. & Antes, G., 14 Sep 2018, In : Cochrane Database of Systematic Reviews. 8, ED000127, ED000127.

Research output: Contribution to journalArticle (Academic Journal)

Open Access

Impact of drinking water, sanitation and handwashing with soap on childhood diarrhoeal disease: updated meta-analysis and meta-regression

Wolf, J., Hunter, P. R., Freeman, M. C., Cumming, O., Clasen, T., Bartram, J., Higgins, J. P. T., Johnston, R., Medlicott, K., Boisson, S. & Prüss-Ustün, A., 1 May 2018, In : Tropical Medicine and International Health. 23, 5, p. 508-525 18 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
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77 Citations (Scopus)
299 Downloads (Pure)

Impact of placebo arms on outcomes in antidepressant trials: systematic review and meta-regression analysis

Salanti, G., Chaimani, A., Furukawa, T. A., Higgins, J. P. T., Ogawa, Y., Cipriani, A. & Egger, M., 1 Oct 2018, In : International Journal of Epidemiology. 47, 5, p. 1454-1464 11 p., dyy076.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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13 Citations (Scopus)
185 Downloads (Pure)

Label-invariant models for the analysis of meta-epidemiological data

Rhodes, K. M., Mawdsley, D., Turner, R. M., Jones, H. E., Savović, J. & Higgins, J. P. T., 15 Jan 2018, In : Statistics in Medicine. 37, 1, p. 60-70 11 p., 7491.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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5 Citations (Scopus)
292 Downloads (Pure)

MELODI: Mining Enriched Literature Objects to Derive Intermediates

Elsworth, B., Dawe, K., Vincent, E., Langdon, R., Lynch, B., Martin, R., Relton, C., Higgins, J. & Gaunt, T., Apr 2018, In : International Journal of Epidemiology. 47, 2, p. 369–379 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1 Citation (Scopus)
266 Downloads (Pure)

Methods to calculate uncertainty in the estimated overall effect size from a random-effects meta-analysis

Veroniki, A. A., Jackson, D., Bender, R., Kuss, O., Langan, D., Higgins, J. P. T., Knapp, G. & Salanti, G., 21 Aug 2018, In : Research Synthesis Methods.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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20 Citations (Scopus)
128 Downloads (Pure)

Pre‐emptive versus non pre‐emptive kidney transplantation for end‐stage kidney disease

Olarte Parra, C., Van de Bruaene, C., Weynants, L., Nagler, E. V., McAleenan, A., Elbers, R. G., Higgins, J. & Goetghebeur, E., 10 Dec 2018, In : Cochrane Database of Systematic Reviews. 12, 14 p., CD013073.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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109 Downloads (Pure)

Tools for assessing risk of reporting biases in studies and syntheses of studies: A systematic review

Page, M. J., McKenzie, J. E. & Higgins, J. P. T., Mar 2018, In : BMJ Open. 8, 3, 16 p., e019703.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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37 Citations (Scopus)
255 Downloads (Pure)
2019

Adjusting trial results for biases in meta-analysis: combining data-based evidence on bias with detailed trial assessment

Rhodes, KM., Savović, J., Elbers, G., Jones, H., Higgins, J., Sterne, J., Welton, N. & Turner, RM., 4 Jul 2019, In : Journal of the Royal Statistical Society: Series A. 183, 1, p. 193-209 17 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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120 Downloads (Pure)

Altering the availability or proximity of food, alcohol, and tobacco products to change their selection and consumption

Hollands, G. J., Carter, P., Anwer, S., King, S. E., Jebb, S. A., Ogilvie, D., Shemilt, I., Higgins, J. P. T. & Marteau, T. M., 4 Sep 2019, In : Cochrane Database of Systematic Reviews. 9, p. CD012573 96 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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19 Downloads (Pure)

Design characteristics, risk of bias, and reporting of randomised controlled trials supporting European Medicines Agency approvals of cancer drugs, 2014-2016: Cross-sectional analysis

Naci, H., Davis, C., Savović, J., Higgins, J. P. T., Sterne, J., Gyawali, B., Romo-Sandoval, X., Handley, N. & Booth, C. M., 18 Sep 2019, In : BMJ. 366, 17 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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23 Citations (Scopus)
127 Downloads (Pure)

Diagnostic test accuracy and cost-effectiveness of tests for codeletion of chromosomal arms 1p and 19q in people with glioma

McAleenan, A., Jones, H. E., Kernohan, A., Faulkner, C. L., Palmer, A., Dawson, S., Wragg, C., Jefferies, S., Brandner, S., Vale, L., Higgins, J. P. T. & Kurian, K. M., 1 Aug 2019, In : Cochrane Database of Systematic Reviews. 2019, 8, p. 1-25 27 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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18 Downloads (Pure)