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Research Output

Label-invariant models for the analysis of meta-epidemiological data

Rhodes, K. M., Mawdsley, D., Turner, R. M., Jones, H. E., Savović, J. & Higgins, J. P. T., 15 Jan 2018, In : Statistics in Medicine. 37, 1, p. 60-70 11 p., 7491.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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5 Citations (Scopus)
292 Downloads (Pure)

Lack of evidence for the efficacy of memantine in mild Alzheimer disease

Schneider, L. S., Dagerman, K. S., Higgins, J. P. T. & McShane, R., 2011, In : Archives of Neurology. 68, 8, p. 991-8 8 p.

Research output: Contribution to journalArticle (Academic Journal)

178 Citations (Scopus)

Living systematic reviews: an emerging opportunity to narrow the evidence-practice gap

Elliott, J. H., Turner, T., Clavisi, O., Thomas, J., Higgins, J. P. T., Mavergames, C. & Gruen, R. L., Feb 2014, In : PLoS Medicine. 11, 2, p. e1001603

Research output: Contribution to journalArticle (Academic Journal)

150 Citations (Scopus)

Machine learning to assist risk of bias assessments in systematic reviews

Millard, L. A. C., Flach, P. A. & Higgins, J. P. T., 1 Feb 2016, In : International Journal of Epidemiology. 45, 1, p. 266-277 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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14 Citations (Scopus)
305 Downloads (Pure)

Making the best use of available evidence: the case of new generation antidepressants: a response to: are all antidepressants equal?

Barbui, C., Cipriani, A., Furukawa, T. A., Salanti, G., Higgins, J. P. T., Churchill, R., Watanabe, N., Nakagawa, A., Omori, I. M. & Geddes, J. R., Nov 2009, In : Evidence-Based Mental Health. 12, 4, p. 101-4 4 p.

Research output: Contribution to journalArticle (Academic Journal)

2 Citations (Scopus)

MELODI: Mining Enriched Literature Objects to Derive Intermediates

Elsworth, B., Dawe, K., Vincent, E., Langdon, R., Lynch, B., Martin, R., Relton, C., Higgins, J. & Gaunt, T., Apr 2018, In : International Journal of Epidemiology. 47, 2, p. 369–379 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1 Citation (Scopus)
266 Downloads (Pure)

Meta-analysis and subgroups

Borenstein, M. & Higgins, J. P. T., Apr 2013, In : Prevention Science. 14, 2, p. 134-43 10 p.

Research output: Contribution to journalArticle (Academic Journal)

123 Citations (Scopus)

Meta-analysis of time-to-event data: a comparison of two-stage methods

Simmonds, M. C., Tierney, J., Bowden, J. & Higgins, J. P., Sep 2011, In : Research Synthesis Methods. 2, 3, p. 139-49 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Methodological features of clinical pharmacokinetic–pharmacodynamic studies of antibacterials and antifungals: a systematic review

Mcaleenan, A., Ambrose, P. G., Bhavnani, S. M., Drusano, G. L., Hope, W. W., Mouton, J. W., Higgins, J. P. T. & Macgowan, A. P., 21 Feb 2020, In : Journal of Antimicrobial Chemotherapy. 16 p., dkaa005.

Research output: Contribution to journalReview article (Academic Journal)

Methods to calculate uncertainty in the estimated overall effect size from a random-effects meta-analysis

Veroniki, A. A., Jackson, D., Bender, R., Kuss, O., Langan, D., Higgins, J. P. T., Knapp, G. & Salanti, G., 21 Aug 2018, In : Research Synthesis Methods.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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20 Citations (Scopus)
128 Downloads (Pure)

Methods to estimate the between-study variance and its uncertainty in meta-analysis

Veroniki, A. A., Jackson, D., Viechtbauer, W., Bender, R., Bowden, J., Knapp, G., Kuss, O., Higgins, J. P. T., Langan, D. & Salanti, G., 1 Mar 2016, In : Research Synthesis Methods. 7, 1, p. 55-79 25 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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251 Citations (Scopus)
619 Downloads (Pure)

Multiplicity of data in trial reports and the reliability of meta-analyses: empirical study

Tendal, B., Nüesch, E., Higgins, J. P. T., Jüni, P. & Gøtzsche, P. C., 2011, In : BMJ. 343, p. d4829

Research output: Contribution to journalArticle (Academic Journal)

28 Citations (Scopus)

Network meta-analysis: A norm for comparative effectiveness?

Higgins, J. P. T. & Welton, N. J., 15 Aug 2015, In : Lancet. 386, 9994, p. 628-630 3 p.

Research output: Contribution to journalComment/debate (Academic Journal)

Open Access
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29 Citations (Scopus)
469 Downloads (Pure)

Network Meta-Analysis of Oral Anticoagulants for Primary Prevention, Treatment and Secondary Prevention of Venous Thromboembolic Disease, and for Prevention of Stroke in Atrial Fibrillation

Lopez-Lopez, J. A., Sterne, J., Bodalia, P. N., Bryden, P. A., Davies, P., Okoli, G. N., Thom, H., Caldwell, D. M., Dias, S., Eaton, D., Higgins, J., Hollingworth, W., Salisbury, C., Savovic, J., Sofat, R., Stephens-Boal, A., Welton, N. J. & Hingorani, A., Nov 2015, In : Value in Health. 18, 7, p. A374

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)

Network meta-analysis of rare events using the Mantel-Haenszel method

Efthimiou, O., Rücker, G., Schwarzer, G., Higgins, J., Egger, M. & Salanti, G., 20 Jul 2019, In : Statistics in Medicine. 38, 16, p. 2992-3012 21 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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5 Citations (Scopus)
50 Downloads (Pure)

Non-invasive prenatal diagnostic test accuracy for fetal sex using cell-free DNA a review and meta-analysis

Wright, C. F., Wei, Y., Higgins, J. P. T. & Sagoo, G. S., 2012, In : BMC Research Notes. 5, p. 476

Research output: Contribution to journalArticle (Academic Journal)

52 Citations (Scopus)

Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis

López-López, J. A., Sterne, J. A. C., Thom, H. H. Z., Higgins, J. P. T., Hingorani, A. D., Okoli, G. N., Davies, P. A., Bodalia, P. N., Bryden, P. A., Welton, N. J., Hollingworth, W., Caldwell, D. M., Savović, J., Dias, S., Salisbury, C., Eaton, D., Stephens-Boal, A. & Sofat, R., 28 Nov 2017, In : BMJ. 359, j5058.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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142 Citations (Scopus)
359 Downloads (Pure)
Open Access
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65 Citations (Scopus)
346 Downloads (Pure)

Personal financial incentives for changing habitual health-related behaviors: A systematic review and meta-analysis

Mantzari, E., Vogt, F., Shemilt, I., Wei, Y., Higgins, J. P. T. & Marteau, T. M., 12 Mar 2015, In : Preventive Medicine.

Research output: Contribution to journalArticle (Academic Journal)

108 Citations (Scopus)

Planning future studies based on the conditional power of a meta-analysis

Roloff, V., Higgins, J. P. T. & Sutton, A. J., 2013, In : Statistics in Medicine. 32, 1, p. 11-24 14 p.

Research output: Contribution to journalArticle (Academic Journal)

35 Citations (Scopus)

Portion, package or tableware size for changing selection and consumption of food, alcohol and tobacco

Hollands, G. J., Shemilt, I., Marteau, T. M., Jebb, S. A., Lewis, H. B., Wei, Y., Higgins, J. P. & Ogilvie, D., 14 Sep 2015, In : Cochrane Database of Systematic Reviews. 9, p. CD011045

Research output: Contribution to journalArticle (Academic Journal)

79 Citations (Scopus)

Predicting the extent of heterogeneity in meta-analysis, using empirical data from the Cochrane Database of Systematic Reviews

Turner, R. M., Davey, J., Clarke, M. J., Thompson, S. G. & Higgins, J. P., 2012, In : International Journal of Epidemiology. 41, 3, p. 818-27 10 p.

Research output: Contribution to journalArticle (Academic Journal)

342 Citations (Scopus)

Predictive distributions for between-study heterogeneity and simple methods for their application in Bayesian meta-analysis

Turner, R. M., Jackson, D., Wei, Y., Thompson, S. G. & Higgins, J. P. T., 5 Dec 2014, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

85 Citations (Scopus)

Predictive distributions were developed for the extent of heterogeneity in meta-analyses of continuous outcome data

Rhodes, K. M., Turner, R. M. & Higgins, J. P. T., 7 Oct 2014, In : Journal of Clinical Epidemiology.

Research output: Contribution to journalArticle (Academic Journal)

110 Citations (Scopus)

Pre‐emptive versus non pre‐emptive kidney transplantation for end‐stage kidney disease

Olarte Parra, C., Van de Bruaene, C., Weynants, L., Nagler, E. V., McAleenan, A., Elbers, R. G., Higgins, J. & Goetghebeur, E., 10 Dec 2018, In : Cochrane Database of Systematic Reviews. 12, 14 p., CD013073.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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109 Downloads (Pure)

Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation

Shamseer, L., Moher, D., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P., Stewart, L. A. & PRISMA-P Group, 2 Jan 2015, In : BMJ. 349, 25 p., g7647.

Research output: Contribution to journalArticle (Academic Journal)

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1056 Downloads (Pure)

Prognostic value of test(S) for O 6 -methylguanine-DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide

McAleenan, A., Howell, A., Kernohan, A., Faulkner, C. L., Dawson, S., Wragg, C., Jefferies, S., Brandner, S., Vale, L., Higgins, J. P. T. & Kurian, K. M., 30 Apr 2019, In : Cochrane Database of Systematic Reviews. 2019, 4, 18 p., CD013316.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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51 Downloads (Pure)
8 Citations (Scopus)

Rate-constrained ranking and the rate-weighted AUC

Millard, L. A. C., Flach, P. A. & Higgins, J. P. T., 1 Jan 2014, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Calders, T., Esposito, F., Hullermeier, E. & Meo, R. (eds.). PART 2 ed. Springer Verlag, Vol. 8725 LNAI. p. 386-403 18 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 8725 LNAI, no. PART 2).

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

4 Citations (Scopus)

Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials

Sterne, J. A. C., Sutton, A. J., Ioannidis, J. P. A., Terrin, N., Jones, D. R., Lau, J., Carpenter, J., Rücker, G., Harbord, R. M., Schmid, C. H., Tetzlaff, J., Deeks, J. J., Peters, J., Macaskill, P., Schwarzer, G., Duval, S., Altman, D. G., Moher, D. & Higgins, J. P. T., 2011, In : BMJ. 343, p. d4002

Research output: Contribution to journalArticle (Academic Journal)

2315 Citations (Scopus)

Reporting of industry funded study outcome data: comparison of confidential and published data on the safety and effectiveness of rhBMP-2 for spinal fusion

Rodgers, M. A., Brown, J. V. E., Heirs, M. K., Higgins, J. P. T., Mannion, R. J., Simmonds, M. C. & Stewart, L. A., 2013, In : BMJ. 346, p. f3981

Research output: Contribution to journalArticle (Academic Journal)

51 Citations (Scopus)

Rethinking the assessment of risk of bias due to selective reporting: a cross-sectional study

Page, M. J. & Higgins, J. PT., 8 Jul 2016, In : Systematic Reviews. 5, 8 p., 108.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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15 Citations (Scopus)
308 Downloads (Pure)
Open Access
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151 Downloads (Pure)

Risk of neuropsychiatric adverse events associated with varenicline: systematic review and meta-analysis

Thomas, K. H., Martin, R. M., Knipe, D. W., Higgins, J. P. T. & Gunnell, D., 12 Mar 2015, In : BMJ. 350, 11 p., h1109.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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73 Citations (Scopus)
283 Downloads (Pure)

Risk of nosocomial respiratory syncytial virus infection and effectiveness of control measures to prevent transmission events: a systematic review

French, C. E., McKenzie, B., Coope, C. M., Rajanaidu, S., Paranthaman, K., Pebody, R., Nguyen-Van-Tam, J., Higgins, J. P. T. & Beck, C. R., Jul 2016, In : Influenza and Other Respiratory Viruses. 10, 4, p. 268-290 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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36 Citations (Scopus)
294 Downloads (Pure)

RoB 2: a revised tool for assessing risk of bias in randomised trials

Sterne, J. A. C., Savović, J., Page, M. J., Elbers, R. G., Blencowe, N. S., Boutron, I., Cates, C. J., Cheng, H-Y., Corbett, M. S., Eldridge, S. M., Emberson, J. R., Hernán, M. A., Hopewell, S., Hróbjartsson, A., Junqueira, D. R., Juni, P., Kirkham, J. J., Lasserson, T., Li, T., McAleenan, A. & 8 others, Reeves, B. C., Shepperd, S., Shrier, I., Stewart, L. A., Tilling, K., White, I. R., Whiting, P. F. & Higgins, J. P. T., 28 Aug 2019, In : BMJ. 366, 8 p., l4898.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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496 Citations (Scopus)
381 Downloads (Pure)

ROBINS-I: a tool for assessing risk of bias in non-randomized studies of interventions

Sterne, J., Hernán, M. A., Reeves, B., Savović, J., Berkman, N. D., Viswanathan, M., Henry, D., Altman, D. G., Ansari, M. T., Boutron, I., Carpenter, J. R., Chan, A-W., Churchill, R., Deeks, J. J., Hróbjartsson, A., Kirkham, J., Juni, P., Loke, Y. K., Pigott, T. D., Ramsay, C. R. & 14 others, Regidor, D., Rothstein, H. R., Sandhu, L., Schünemann, H., Shea, B., Shrier, I., Tugwell, P., Turner, L., Valentine, J. C., Waddington, H., Waters, E., Wells, G. A., Whiting, P. & Higgins, J., 12 Oct 2016, In : BMJ. 355, 7 p., i4919.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1890 Citations (Scopus)
447 Downloads (Pure)

ROBIS: A new tool to assess risk of bias in systematic reviews was developed

Whiting, P. F., Savovic, J., Higgins, J. P. T., Caldwell, D. M., Reeves, B. C., Shea, B., Davies, P., Kleijnen, J., Churchill, R. C. & ROBIS Group, Jan 2016, In : Journal of Clinical Epidemiology. 69, p. 225-324 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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356 Citations (Scopus)
754 Downloads (Pure)

Safety and Effectiveness of Recombinant Human Bone Morphogenetic Protein-2 for Spinal Fusion: A Meta-analysis of Individual-Participant Data

Simmonds, M. C., Brown, J. V. E., Heirs, M. K., Higgins, J. P. T., Mannion, R. J., Rodgers, M. A. & Stewart, L. A., 18 Jun 2013, In : Annals of Internal Medicine. 158, 12, p. 877-89 13 p.

Research output: Contribution to journalArticle (Academic Journal)

221 Citations (Scopus)

Sample size calculation for meta-epidemiological studies

Giraudeau, B., Higgins, J. P. T., Tavernier, E. & Trinquart, L., 19 Aug 2015, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

18 Citations (Scopus)

Screening strategies for atrial fibrillation: A systematic review and cost-effectiveness analysis

Welton, N. J., McAleenan, A., Thom, H. H. Z., Davies, P., Hollingworth, W., Higgins, J. P. T., Okoli, G., Sterne, J. A. C., Feder, G., Eaton, D., Hingorani, A., Fawsitt, C., Lobban, T., Bryden, P., Richards, A. & Sofat, R., 1 May 2017, In : Health Technology Assessment. 21, 29, p. vii-235 272 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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48 Citations (Scopus)
658 Downloads (Pure)
Open Access
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1 Citation (Scopus)
42 Downloads (Pure)

Sequential methods for random-effects meta-analysis

Higgins, J. P. T., Whitehead, A. & Simmonds, M., 2011, In : Statistics in Medicine. 30, 9, p. 903-21 19 p.

Research output: Contribution to journalArticle (Academic Journal)

181 Citations (Scopus)

Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis

Sagoo, G. S., Tatt, I., Salanti, G., Butterworth, AS., Sarwar, N., van Maarle, M., Jukema, JW., Wiman, B., Kastelein, JJP., Bennet, A., de Faire, U., Danesh, J. & Higgins, J. P. T., 2008, In : American Journal of Epidemiology. 168, 11, p. 1233-1246 14 p.

Research output: Contribution to journalArticle (Academic Journal)

97 Citations (Scopus)

STrengthening the REporting of Genetic Association studies (STREGA): an extension of the STROBE Statement

Little, J., Higgins, J. P. T., Ioannidis, J. P. A., Moher, D., Gagnon, F., von Elm, E., Khoury, M. J., Cohen, B., Davey Smith, G., Grimshaw, J., Scheet, P., Gwinn, M., Williamson, R. E., Zou, G. Y., Hutchings, K., Johnson, C. Y., Tait, V., Wiens, M., Golding, J., van Duijn, C. & 10 others, McLaughlin, J., Paterson, A., Wells, G., Fortier, I., Freedman, M., Zecevic, M., King, R., Infante-Rivard, C., Stewart, A. & Birkett, N., 3 Feb 2009, In : Annals of Internal Medicine. 150, 3, p. 206-15 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Summarising and validating test accuracy results across multiple studies for use in clinical practice

Riley, R. D., Ahmed, I., Debray, T. P. A., Willis, B. H., Noordzij, J. P., Higgins, J. P. T. & Deeks, J. J., 20 Mar 2015, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

23 Citations (Scopus)

Synthesising quantitative evidence in systematic reviews of complex health interventions

Higgins, J., Lopez-Lopez, J. A., Becker, B., Davies, S., Dawson, S., Grimshaw, J. M., McGuinness, L., Moore, T., Rehfuess, E. A., Thomas, J. & Caldwell, D., 25 Jan 2019, In : BMJ Global Health. 4, 15 p., e000858.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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253 Downloads (Pure)

Synthesizing evidence on complex interventions: how meta-analytical, qualitative, and mixed-method approaches can contribute

Petticrew, M., Rehfuess, E., Noyes, J., Higgins, J. P. T., Mayhew, A., Pantoja, T., Shemilt, I. & Sowden, A., 14 Aug 2013, In : Journal of Clinical Epidemiology.

Research output: Contribution to journalArticle (Academic Journal)

126 Citations (Scopus)

Systematic reviews in health research

Tanner-Smith, E. E., Egger, M. & Higgins, J., 1 Sep 2019, In : Research Synthesis Methods. 10, 3, p. 310-311 2 p.

Research output: Contribution to journalEditorial (Academic Journal)

1 Citation (Scopus)

Systematic reviews of genetic association studies. Human Genome Epidemiology Network

Sagoo, G. S., Little, J. & Higgins, J. P. T., 3 Mar 2009, In : PLoS Medicine. 6, 3, p. e28

Research output: Contribution to journalArticle (Academic Journal)

117 Citations (Scopus)