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Research Output

Article (Academic Journal)

Methods to estimate the between-study variance and its uncertainty in meta-analysis

Veroniki, A. A., Jackson, D., Viechtbauer, W., Bender, R., Bowden, J., Knapp, G., Kuss, O., Higgins, J. P. T., Langan, D. & Salanti, G., 1 Mar 2016, In : Research Synthesis Methods. 7, 1, p. 55-79 25 p.

Research output: Contribution to journalArticle (Academic Journal)

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251 Citations (Scopus)
621 Downloads (Pure)

Multiplicity of data in trial reports and the reliability of meta-analyses: empirical study

Tendal, B., Nüesch, E., Higgins, J. P. T., Jüni, P. & Gøtzsche, P. C., 2011, In : BMJ. 343, p. d4829

Research output: Contribution to journalArticle (Academic Journal)

28 Citations (Scopus)

Network Meta-Analysis of Oral Anticoagulants for Primary Prevention, Treatment and Secondary Prevention of Venous Thromboembolic Disease, and for Prevention of Stroke in Atrial Fibrillation

Lopez-Lopez, J. A., Sterne, J., Bodalia, P. N., Bryden, P. A., Davies, P., Okoli, G. N., Thom, H., Caldwell, D. M., Dias, S., Eaton, D., Higgins, J., Hollingworth, W., Salisbury, C., Savovic, J., Sofat, R., Stephens-Boal, A., Welton, N. J. & Hingorani, A., Nov 2015, In : Value in Health. 18, 7, p. A374

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)

Network meta-analysis of rare events using the Mantel-Haenszel method

Efthimiou, O., Rücker, G., Schwarzer, G., Higgins, J., Egger, M. & Salanti, G., 20 Jul 2019, In : Statistics in Medicine. 38, 16, p. 2992-3012 21 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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5 Citations (Scopus)
51 Downloads (Pure)

Non-invasive prenatal diagnostic test accuracy for fetal sex using cell-free DNA a review and meta-analysis

Wright, C. F., Wei, Y., Higgins, J. P. T. & Sagoo, G. S., 2012, In : BMC Research Notes. 5, p. 476

Research output: Contribution to journalArticle (Academic Journal)

52 Citations (Scopus)

Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis

López-López, J. A., Sterne, J. A. C., Thom, H. H. Z., Higgins, J. P. T., Hingorani, A. D., Okoli, G. N., Davies, P. A., Bodalia, P. N., Bryden, P. A., Welton, N. J., Hollingworth, W., Caldwell, D. M., Savović, J., Dias, S., Salisbury, C., Eaton, D., Stephens-Boal, A. & Sofat, R., 28 Nov 2017, In : BMJ. 359, j5058.

Research output: Contribution to journalArticle (Academic Journal)

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142 Citations (Scopus)
359 Downloads (Pure)
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65 Citations (Scopus)
346 Downloads (Pure)

Personal financial incentives for changing habitual health-related behaviors: A systematic review and meta-analysis

Mantzari, E., Vogt, F., Shemilt, I., Wei, Y., Higgins, J. P. T. & Marteau, T. M., 12 Mar 2015, In : Preventive Medicine.

Research output: Contribution to journalArticle (Academic Journal)

108 Citations (Scopus)

Planning future studies based on the conditional power of a meta-analysis

Roloff, V., Higgins, J. P. T. & Sutton, A. J., 2013, In : Statistics in Medicine. 32, 1, p. 11-24 14 p.

Research output: Contribution to journalArticle (Academic Journal)

35 Citations (Scopus)

Portion, package or tableware size for changing selection and consumption of food, alcohol and tobacco

Hollands, G. J., Shemilt, I., Marteau, T. M., Jebb, S. A., Lewis, H. B., Wei, Y., Higgins, J. P. & Ogilvie, D., 14 Sep 2015, In : Cochrane Database of Systematic Reviews. 9, p. CD011045

Research output: Contribution to journalArticle (Academic Journal)

79 Citations (Scopus)

Predicting the extent of heterogeneity in meta-analysis, using empirical data from the Cochrane Database of Systematic Reviews

Turner, R. M., Davey, J., Clarke, M. J., Thompson, S. G. & Higgins, J. P., 2012, In : International Journal of Epidemiology. 41, 3, p. 818-27 10 p.

Research output: Contribution to journalArticle (Academic Journal)

342 Citations (Scopus)

Predictive distributions for between-study heterogeneity and simple methods for their application in Bayesian meta-analysis

Turner, R. M., Jackson, D., Wei, Y., Thompson, S. G. & Higgins, J. P. T., 5 Dec 2014, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

85 Citations (Scopus)

Predictive distributions were developed for the extent of heterogeneity in meta-analyses of continuous outcome data

Rhodes, K. M., Turner, R. M. & Higgins, J. P. T., 7 Oct 2014, In : Journal of Clinical Epidemiology.

Research output: Contribution to journalArticle (Academic Journal)

110 Citations (Scopus)

Pre‐emptive versus non pre‐emptive kidney transplantation for end‐stage kidney disease

Olarte Parra, C., Van de Bruaene, C., Weynants, L., Nagler, E. V., McAleenan, A., Elbers, R. G., Higgins, J. & Goetghebeur, E., 10 Dec 2018, In : Cochrane Database of Systematic Reviews. 12, 14 p., CD013073.

Research output: Contribution to journalArticle (Academic Journal)

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109 Downloads (Pure)

Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation

Shamseer, L., Moher, D., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P., Stewart, L. A. & PRISMA-P Group, 2 Jan 2015, In : BMJ. 349, 25 p., g7647.

Research output: Contribution to journalArticle (Academic Journal)

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1057 Downloads (Pure)

Prognostic value of test(S) for O 6 -methylguanine-DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide

McAleenan, A., Howell, A., Kernohan, A., Faulkner, C. L., Dawson, S., Wragg, C., Jefferies, S., Brandner, S., Vale, L., Higgins, J. P. T. & Kurian, K. M., 30 Apr 2019, In : Cochrane Database of Systematic Reviews. 2019, 4, 18 p., CD013316.

Research output: Contribution to journalArticle (Academic Journal)

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51 Downloads (Pure)
8 Citations (Scopus)

Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials

Sterne, J. A. C., Sutton, A. J., Ioannidis, J. P. A., Terrin, N., Jones, D. R., Lau, J., Carpenter, J., Rücker, G., Harbord, R. M., Schmid, C. H., Tetzlaff, J., Deeks, J. J., Peters, J., Macaskill, P., Schwarzer, G., Duval, S., Altman, D. G., Moher, D. & Higgins, J. P. T., 2011, In : BMJ. 343, p. d4002

Research output: Contribution to journalArticle (Academic Journal)

2315 Citations (Scopus)

Reporting of industry funded study outcome data: comparison of confidential and published data on the safety and effectiveness of rhBMP-2 for spinal fusion

Rodgers, M. A., Brown, J. V. E., Heirs, M. K., Higgins, J. P. T., Mannion, R. J., Simmonds, M. C. & Stewart, L. A., 2013, In : BMJ. 346, p. f3981

Research output: Contribution to journalArticle (Academic Journal)

51 Citations (Scopus)

Rethinking the assessment of risk of bias due to selective reporting: a cross-sectional study

Page, M. J. & Higgins, J. PT., 8 Jul 2016, In : Systematic Reviews. 5, 8 p., 108.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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15 Citations (Scopus)
308 Downloads (Pure)
Open Access
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151 Downloads (Pure)

Risk of neuropsychiatric adverse events associated with varenicline: systematic review and meta-analysis

Thomas, K. H., Martin, R. M., Knipe, D. W., Higgins, J. P. T. & Gunnell, D., 12 Mar 2015, In : BMJ. 350, 11 p., h1109.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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73 Citations (Scopus)
285 Downloads (Pure)

Risk of nosocomial respiratory syncytial virus infection and effectiveness of control measures to prevent transmission events: a systematic review

French, C. E., McKenzie, B., Coope, C. M., Rajanaidu, S., Paranthaman, K., Pebody, R., Nguyen-Van-Tam, J., Higgins, J. P. T. & Beck, C. R., Jul 2016, In : Influenza and Other Respiratory Viruses. 10, 4, p. 268-290 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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36 Citations (Scopus)
294 Downloads (Pure)

RoB 2: a revised tool for assessing risk of bias in randomised trials

Sterne, J. A. C., Savović, J., Page, M. J., Elbers, R. G., Blencowe, N. S., Boutron, I., Cates, C. J., Cheng, H-Y., Corbett, M. S., Eldridge, S. M., Emberson, J. R., Hernán, M. A., Hopewell, S., Hróbjartsson, A., Junqueira, D. R., Juni, P., Kirkham, J. J., Lasserson, T., Li, T., McAleenan, A. & 8 others, Reeves, B. C., Shepperd, S., Shrier, I., Stewart, L. A., Tilling, K., White, I. R., Whiting, P. F. & Higgins, J. P. T., 28 Aug 2019, In : BMJ. 366, 8 p., l4898.

Research output: Contribution to journalArticle (Academic Journal)

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496 Citations (Scopus)
383 Downloads (Pure)

ROBINS-I: a tool for assessing risk of bias in non-randomized studies of interventions

Sterne, J., Hernán, M. A., Reeves, B., Savović, J., Berkman, N. D., Viswanathan, M., Henry, D., Altman, D. G., Ansari, M. T., Boutron, I., Carpenter, J. R., Chan, A-W., Churchill, R., Deeks, J. J., Hróbjartsson, A., Kirkham, J., Juni, P., Loke, Y. K., Pigott, T. D., Ramsay, C. R. & 14 others, Regidor, D., Rothstein, H. R., Sandhu, L., Schünemann, H., Shea, B., Shrier, I., Tugwell, P., Turner, L., Valentine, J. C., Waddington, H., Waters, E., Wells, G. A., Whiting, P. & Higgins, J., 12 Oct 2016, In : BMJ. 355, 7 p., i4919.

Research output: Contribution to journalArticle (Academic Journal)

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1890 Citations (Scopus)
448 Downloads (Pure)

ROBIS: A new tool to assess risk of bias in systematic reviews was developed

Whiting, P. F., Savovic, J., Higgins, J. P. T., Caldwell, D. M., Reeves, B. C., Shea, B., Davies, P., Kleijnen, J., Churchill, R. C. & ROBIS Group, Jan 2016, In : Journal of Clinical Epidemiology. 69, p. 225-324 10 p.

Research output: Contribution to journalArticle (Academic Journal)

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356 Citations (Scopus)
755 Downloads (Pure)

Safety and Effectiveness of Recombinant Human Bone Morphogenetic Protein-2 for Spinal Fusion: A Meta-analysis of Individual-Participant Data

Simmonds, M. C., Brown, J. V. E., Heirs, M. K., Higgins, J. P. T., Mannion, R. J., Rodgers, M. A. & Stewart, L. A., 18 Jun 2013, In : Annals of Internal Medicine. 158, 12, p. 877-89 13 p.

Research output: Contribution to journalArticle (Academic Journal)

221 Citations (Scopus)

Sample size calculation for meta-epidemiological studies

Giraudeau, B., Higgins, J. P. T., Tavernier, E. & Trinquart, L., 19 Aug 2015, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

18 Citations (Scopus)

Screening strategies for atrial fibrillation: A systematic review and cost-effectiveness analysis

Welton, N. J., McAleenan, A., Thom, H. H. Z., Davies, P., Hollingworth, W., Higgins, J. P. T., Okoli, G., Sterne, J. A. C., Feder, G., Eaton, D., Hingorani, A., Fawsitt, C., Lobban, T., Bryden, P., Richards, A. & Sofat, R., 1 May 2017, In : Health Technology Assessment. 21, 29, p. vii-235 272 p.

Research output: Contribution to journalArticle (Academic Journal)

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48 Citations (Scopus)
662 Downloads (Pure)
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1 Citation (Scopus)
42 Downloads (Pure)

Sequential methods for random-effects meta-analysis

Higgins, J. P. T., Whitehead, A. & Simmonds, M., 2011, In : Statistics in Medicine. 30, 9, p. 903-21 19 p.

Research output: Contribution to journalArticle (Academic Journal)

181 Citations (Scopus)

Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis

Sagoo, G. S., Tatt, I., Salanti, G., Butterworth, AS., Sarwar, N., van Maarle, M., Jukema, JW., Wiman, B., Kastelein, JJP., Bennet, A., de Faire, U., Danesh, J. & Higgins, J. P. T., 2008, In : American Journal of Epidemiology. 168, 11, p. 1233-1246 14 p.

Research output: Contribution to journalArticle (Academic Journal)

97 Citations (Scopus)

STrengthening the REporting of Genetic Association studies (STREGA): an extension of the STROBE Statement

Little, J., Higgins, J. P. T., Ioannidis, J. P. A., Moher, D., Gagnon, F., von Elm, E., Khoury, M. J., Cohen, B., Davey Smith, G., Grimshaw, J., Scheet, P., Gwinn, M., Williamson, R. E., Zou, G. Y., Hutchings, K., Johnson, C. Y., Tait, V., Wiens, M., Golding, J., van Duijn, C. & 10 others, McLaughlin, J., Paterson, A., Wells, G., Fortier, I., Freedman, M., Zecevic, M., King, R., Infante-Rivard, C., Stewart, A. & Birkett, N., 3 Feb 2009, In : Annals of Internal Medicine. 150, 3, p. 206-15 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Summarising and validating test accuracy results across multiple studies for use in clinical practice

Riley, R. D., Ahmed, I., Debray, T. P. A., Willis, B. H., Noordzij, J. P., Higgins, J. P. T. & Deeks, J. J., 20 Mar 2015, In : Statistics in Medicine.

Research output: Contribution to journalArticle (Academic Journal)

23 Citations (Scopus)

Synthesising quantitative evidence in systematic reviews of complex health interventions

Higgins, J., Lopez-Lopez, J. A., Becker, B., Davies, S., Dawson, S., Grimshaw, J. M., McGuinness, L., Moore, T., Rehfuess, E. A., Thomas, J. & Caldwell, D., 25 Jan 2019, In : BMJ Global Health. 4, 15 p., e000858.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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253 Downloads (Pure)

Synthesizing evidence on complex interventions: how meta-analytical, qualitative, and mixed-method approaches can contribute

Petticrew, M., Rehfuess, E., Noyes, J., Higgins, J. P. T., Mayhew, A., Pantoja, T., Shemilt, I. & Sowden, A., 14 Aug 2013, In : Journal of Clinical Epidemiology.

Research output: Contribution to journalArticle (Academic Journal)

126 Citations (Scopus)

Systematic reviews of genetic association studies. Human Genome Epidemiology Network

Sagoo, G. S., Little, J. & Higgins, J. P. T., 3 Mar 2009, In : PLoS Medicine. 6, 3, p. e28

Research output: Contribution to journalArticle (Academic Journal)

117 Citations (Scopus)

Systematic review with meta-analysis: the gastrointestinal benefits of COX-2 selective inhibitors with concomitant use of low-dose aspirin

Yuan, J., Yang, M., Threapleton, D. E., Qi, X. S., Ye, D. Q., Mao, C., Tang, J. L. & Higgins, J. P. T., Oct 2016, In : Alimentary Pharmacology and Therapeutics. 44, 8, p. 785–795 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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5 Citations (Scopus)
441 Downloads (Pure)

The albatross plot: A novel graphical tool for presenting results of diversely reported studies in a systematic review

Harrison, S., Jones, H., Martin, R., Lewis, S. & Higgins, J., 1 Sep 2017, In : Research Synthesis Methods. 8, 3, p. 281-289 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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25 Citations (Scopus)
311 Downloads (Pure)

The association between proximity to animal-feeding operations and community health: A protocol for updating a systematic review

O'Connor, A. M., Auvermann, B. W., Higgins, J. P. T., Kirychuk, S. P., Sargeant, J. M., Von Essen, S. G., Glanville, J. M. & Wood, H., 8 Sep 2014, In : Systematic Reviews. 3, 1, 99.

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)

The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis

Gouda, H. N., Sagoo, G. S., Harding, A-H., Yates, J., Sandhu, M. S. & Higgins, J. P. T., 15 Mar 2010, In : American Journal of Epidemiology. 171, 6, p. 645-55 11 p.

Research output: Contribution to journalArticle (Academic Journal)

159 Citations (Scopus)
Open Access
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7 Citations (Scopus)
395 Downloads (Pure)

The Cochrane Collaboration's tool for assessing risk of bias in randomised trials

Higgins, J. P. T., Altman, D. G., Gøtzsche, P. C., Jüni, P., Moher, D., Oxman, A. D., Savovic, J., Schulz, K. F., Weeks, L., Sterne, J. A. C. & Cochrane Bias Methods Group, 18 Oct 2011, In : BMJ. 343, p. d5928 9 p.

Research output: Contribution to journalArticle (Academic Journal)

10461 Citations (Scopus)

The Cost-Effectiveness Of Novel Oral Anticoagulants For The Prevention Of Stroke In Atrial Fibrillation In England And Wales

Thom, H., Hollingworth, W., Bryden, P. A., Sterne, J., Bodalia, P. N., Davies, P., Lopez-Lopez, J. A., Okoli, G. N., Caldwell, D. M., Dias, S., Eaton, D., Higgins, J., Salisbury, C., Savovic, J., Sofat, R., Stephens-Boal, A., Hingorani, A. & Welton, N. J., Nov 2015, In : Value in Health. 18, 7, p. A391-2

Research output: Contribution to journalArticle (Academic Journal)

The impact of study size on meta-analyses: examination of underpowered studies in Cochrane reviews

Turner, R. M., Bird, S. M. & Higgins, J. P. T., 2013, In : PLoS ONE. 8, 3, p. e59202

Research output: Contribution to journalArticle (Academic Journal)

283 Citations (Scopus)

The impact of the COVID-19 pandemic on self-harm and suicidal behaviour: protocol for a living systematic review

John, A., Eyles, E., McGuinness, L. A., Okolie, C., Olorisade, B. K., Schmidt, L., Webb, R. T., Arensman, E., Hawton, K., Kapur, N., Moran, P., O'Connor, R. C., O’Neill, S., Gunnell, D. & Higgins, J. P. T., 25 Jun 2020, In : F1000Research. 9, 10 p., 644.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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18 Downloads (Pure)

The impact of trial characteristics on premature discontinuation of antipsychotics in schizophrenia

Spineli, L. M., Leucht, S., Cipriani, A., Higgins, J. P. T. & Salanti, G., 29 Apr 2013, In : European Neuropsychopharmacology.

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)

The INVEST project: investigating the use of evidence synthesis in the design and analysis of clinical trials

Clayton, G., Smith, I. L., Higgins, J., Mihaylova, B., Thorpe, B., Cicero, R., Lokuge, K., Forman, J. R., Tierney, J. F., White, I. R., Sharples, L. & Jones, H., 15 May 2017, In : Trials. 18, 219, 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
279 Downloads (Pure)

The median and the mode as robust meta-analysis estimators in the presence of small-study effects and outliers

Hartwig, F. P., Davey Smith, G., Schmidt, A. F., Sterne, J. A. C., Higgins, J. P. T. & Bowden, J., 8 May 2020, In : Research Synthesis Methods. 11, 3, p. 397-412 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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