20062020

Research output per year

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Personal profile

Research interests

Karen Luyt holds a tenured clinical-academic position in Neonatal Medicine at the University of Bristol. She works as a clinical neonatologist in the Regional Neonatal Intensive Care unit at St Michael’s Hospital, Bristol, with special interests in brain injury, neuro-intensive care and improving health outcomes in high risk infants. 

Neonatal Neurology and Health Outcomes in high risk infants

Dr Luyt’s laboratory-based research has focused on mechanisms of brain injury and regeneration in the newborn central nervous system. Her translational clinical research concerns evaluation and implementation of evidence-based interventions to reduce neurodisability and mortality in newborns.

 Chief Investigator for:

  • School age outcomes of the DRIFT (Drainage, Irrigation, and Fibrinolyitic Therapy) Trial (NIHR funded). Functional outcome and brain imaging in children who received DRIFT for posthaemorrhagic ventricular dilatation.
  • PReCePT (Prevention of Cerebral Palsy in Preterm Labour) Study – National cluster randomised controlled trial (Health Foundation funded)

Diseases related to this field of research

  • Neurodevelopment
  • Neonatal Brain Injury
  • Cerebral Palsy
  • Health Outcomes
  • Neonatal Mortality

 

Twitter: @Karen.Luyt

 

Research interests

Biography

Karen Luyt read medicine in South Africa and received a CCST in Paediatrics (Neonatal Medicine) in the UK in 2004. She was awarded a Walport Senior Lectureship in 2009 and holds a tenured clinical-academic position in Neonatal Medicine at the University of Bristol. She works as a clinical neonatologist in the Regional Neonatal Intensive Care unit at St Michael’s Hospital, Bristol, with special interests in brain injury, neuro-intensive care and improving health outcomes in high risk infants. 

Leadership Roles:

  • Programme lead for the National Child Mortality Database (NCMD)
  • National clinical lead for the PReCePT (Prevention of Cerebral Palsy in Preterm Labour) Programme
  • Strategic clinical lead for the PERIPrem project
  • Meetings Secretary for the Neonatal Society
  • Academic Lead for the Child Death Overview Group

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Research Output

  • 30 Article (Academic Journal)
  • 2 Conference Contribution (Conference Proceeding)
  • 2 Review article (Academic Journal)

Drainage, Irrigation And Fibrinolytic Therapy (Drift) For Post-Haemorrhagic Ventricular Dilatation: 10-Year Follow-Up Of A Randomised Controlled Trial

Luyt, K., Jary, S. L., Lea, C. L., Young, G. J., Odd, D. E., Miller, H. E., Kmita, G., Williams, C., Blair, P. S., Hollingworth, W., Morgan, M., Smith-Collins, A. P., Walker-Cox, S., Aquilina, K., Pople, I. & Whitelaw, A. G., 4 Jul 2020, In : Archives of Disease in Childhood: Fetal and Neonatal Edition. 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
  • 19 Downloads (Pure)

    Maternal risk factors for the VACTERL association: a EUROCAT case-control study

    Luyt, K., van de Putte, R., Marcelis, C. L. M., Addor, M. C., Cavero-Carbonell, C., Dias, C. M., Draper, E. S., Etxebarriarteun, L., Gatt, M., Khoshnood, B., Kinsner-Ovaskainen, A., Klungsøyr, K., Kurinczuk, J. J., Latos-Bielenska, A., O'Mahony, M. T., Miller, N., Mullaney, C., Nelen, V., Neville, A. J., Perthus, I. & 18 others, Pierini, A., Randrianaivo, H., Rankin, J., Rissmann, A., Rouget, F., Schaub, B., van Rooij, I. A. L. M., Tucker, D., Wellesley, D., Wiesel, A., Zymak-Zakutnia, N., Loane, M., Barisic, I., de Walle, H. E. K., Bergman, J., Roeleveld, N., Brunner, H. G. & Haanappel, C., 22 Apr 2020, In : Birth Defects Research. 112, 9, p. 688 - 698 11 p.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 39 Downloads (Pure)

    Treatment For Post-Haemorrhagic Ventricular Dilatation: A Multiple-Treatments Meta-Analysis

    Mahoney, L., Luyt, K., Harding, D. & Odd, D. E., 20 Apr 2020, (Accepted/In press) In : Frontiers in Pediatrics.

    Research output: Contribution to journalArticle (Academic Journal)