Projects per year
Personal profile
Research interests
As Director of the University of Bristol Proteomics Facility, I run a core research facility that provides a full range of bespoke proteomics services allowing the isolation, identification and quantitation of proteins of interest for researchers within the University of Bristol and to external academic and industrial clients.
The key services provided by the Facility are:
- Protein identification: we can identify the proteins present in anything from a single gel band up to a total cell lysate or tissue homogenate.
- Quantitative Proteomics (eg. TMT and SILAC) for the analysis of changes in protein levels between different samples or conditions.
- Phospho-Proteomics for the identification of phosphorylated proteins and the analysis of changes in phosphorylation between different samples or conditions.
- Interactome Analysis (eg. AP-MS) for the analysis of protein binding partners.
- Secretome analysis.
- Serum proteomics.
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Projects
- 1 Finished
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Enabling advanced analytics for all users of the proteomics facility
Dowsey , A., Davidson, A. D., Heesom, K. J., Matthews, D. A. & Wuelfing, C.
1/01/18 → 8/06/21
Project: Research
Research output
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A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function
McCaughey, J., Stevenson, N. L., Mantell, J. M., Neal, C. R., Heesom, K. & Stephens, D. J., 7 Sep 2021, In: Journal of Cell Science. 134, 17Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)14 Downloads (Pure) -
Arabidopsis thaliana myosin XIK is recruited to the Golgi through interaction with a MyoB receptor
Perico, C., Gao, H., Heesom, K. J., Botchway, S. W. & Sparkes, I. A., 13 Oct 2021, In: Communications Biology. 4, 1, 1182.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile3 Downloads (Pure) -
OmpF Downregulation Mediated by Sigma E or OmpR Activation Confers Cefalexin Resistance in Escherichia coli in the Absence of Acquired β-Lactamases.
Avison, M. B., Dulyayangkul, P., Alzayn, M. M. A., Satapoomin, A. & Heesom, K. J., 18 Oct 2021, (E-pub ahead of print) In: Antimicrobial Agents and Chemotherapy.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Datasets
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A general role for MIA3/TANGO1 in secretory pathway organization and function
Stephens, D. J. (Creator), McCaughey, J. (Contributor), Mantell, J. M. (Contributor), Neal, C. (Contributor) & Heesom, K. J. (Contributor), University of Bristol, 20 Jul 2021
DOI: 10.5523/bris.xbao2ekjv5c124o2k0frhq7v6, http://data.bris.ac.uk/data/dataset/xbao2ekjv5c124o2k0frhq7v6
Dataset