Research output per year
Research output per year
Personal profile
Research interests
As Director of the University of Bristol Proteomics Facility, I run a core research facility that provides a full range of bespoke proteomics services allowing the isolation, identification and quantitation of proteins of interest for researchers within the University of Bristol and to external academic and industrial clients.
The key services provided by the Facility are:
- Protein identification: we can identify the proteins present in anything from a single gel band up to a total cell lysate or tissue homogenate.
- Quantitative Proteomics (eg. TMT and SILAC) for the analysis of changes in protein levels between different samples or conditions.
- Phospho-Proteomics for the identification of phosphorylated proteins and the analysis of changes in phosphorylation between different samples or conditions.
- Interactome Analysis (eg. AP-MS) for the analysis of protein binding partners.
- Secretome analysis.
- Serum proteomics.
Keywords
- Proteomics
- Mass Spectrometry
- Protein Identification
- Protein Quantitation
- Protein Phosphorylation
Fingerprint
Dive into the research topics where Kate J Heesom is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
-
Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics
Dulyayangkul, P., Beavis, T., Lee, W. W. Y., Ardagh, R., Edwards, F., Hamilton, F. W., Head, I. M., Heesom, K. J., Mounsey, O. J., Murarik, M. R., Reding, C., Pinweha, P., Satapoomin, N., Shaw, J. M., Takebayashi, Y., Tooke, C. L., Spencer, J., Williams, P. B. & Avison, M. B., 6 Jun 2024, In: PLoS Pathogens. 20, 6, e1012235.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Improving Nitrofurantoin Resistance Prediction in Escherichia coli from Whole Genome Sequence by Integrating NfsA/B Enzyme Assays
Dulyayangkul, P., Sealey, J. E., Lee, W. W. Y., Satapoomin, A., Reding, C., Heesom, K. J., Williams, P. B. & Avison, M. B., 9 Jul 2024, In: Antimicrobial Agents and Chemotherapy. 68, 7, e00242-24.Research output: Contribution to journal › Article (Academic Journal)
Open AccessFile21 Downloads (Pure) -
Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease
Lay, A. C., Tran, V. D. T., Nair, V., Betin, V. M. S., Hurcombe, J. A., Barrington, A. F., Pope, R. J. P., Burdet, F., Mehl, F., Kryvokhyzha, D., Ahmad, A., C. Sinton, M., Lewis, P., Wilson, M. C., Menon, R., Otto, E. A., Heesom, K. J., C. Looker, H., Nelson, R. G. & Ju, W. & 4 others, , 19 Nov 2024, (E-pub ahead of print) In: Nature Communications. 15, 1, 19 p., 10018.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)7 Downloads (Pure)
Projects
- 1 Finished
-
Enabling advanced analytics for all users of the proteomics facility
Dowsey, A. (Principal Investigator), Davidson, A. D. (Co-Investigator), Heesom, K. J. (Co-Investigator), Matthews, D. A. (Co-Investigator) & Wuelfing, C. (Co-Investigator)
1/01/18 → 8/06/21
Project: Research
Datasets
-
A general role for MIA3/TANGO1 in secretory pathway organization and function
Stephens, D. (Creator), McCaughey, J. (Contributor), Mantell, J. (Contributor), Neal, C. R. (Contributor) & Heesom, K. (Contributor), University of Bristol, 20 Jul 2021
DOI: 10.5523/bris.xbao2ekjv5c124o2k0frhq7v6, http://data.bris.ac.uk/data/dataset/xbao2ekjv5c124o2k0frhq7v6
Dataset