Personal profile
Research interests
As Director of the University of Bristol Proteomics Facility, I run a core research facility that provides a full range of bespoke proteomics services allowing the isolation, identification and quantitation of proteins of interest for researchers within the University of Bristol and to external academic and industrial clients.
The key services provided by the Facility are:
- Protein identification: we can identify the proteins present in anything from a single gel band up to a total cell lysate or tissue homogenate.
- Quantitative Proteomics (eg. TMT and SILAC) for the analysis of changes in protein levels between different samples or conditions.
- Phospho-Proteomics for the identification of phosphorylated proteins and the analysis of changes in phosphorylation between different samples or conditions.
- Interactome Analysis (eg. AP-MS) for the analysis of protein binding partners.
- Secretome analysis.
- Serum proteomics.
Keywords
- Proteomics
- Mass Spectrometry
- Protein Identification
- Protein Quantitation
- Protein Phosphorylation
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Research output
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Pathogenic podocin variants exhibit distinct defects in trafficking, membrane organization, and degradation pathways
Lu, P.-C., Rollason, R., Chou, C.-A., Kuzmuk, V., Heesom, K. J., Saleem, M. A. & Welsh, G. I., 1 Mar 2026, In: European Journal of Cell Biology. 105, 1, 17 p., 151526.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
An extended network for regulation of heme homeostasis in cells
Gallio, A. E., Marson, N. A., Heesom, K. J., Alibhai, D. R., Dugdale, C. A., Basran, J., Hudson, A. J., Raven, E. & al , E., 7 Oct 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 40, p. e2508237122 e2508237122.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access3 Citations (Scopus) -
A Novel Role of Hyaluronan and Its Membrane Receptors, CD44 and RHAMM, in Obesity-Related Kidney Pathology
Qi, B., Musale, V., Weng, X., Banah, A. K., Lawlor, A., Murdoch, C. E., Lay, A. C., Heesom, K. J., Coward, R. J. M., O'Connor, C. L., Ju, W., Bitzer, M., Hills, C. E., Chen, Y. & Kang, L., 14 Nov 2025, In: Biomolecules. 15, 11, 23 p., 1598.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access
Projects
- 1 Finished
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Enabling advanced analytics for all users of the proteomics facility
Dowsey, A. (Principal Investigator), Davidson, A. D. (Co-Investigator), Heesom, K. J. (Co-Investigator), Matthews, D. A. (Co-Investigator) & Wuelfing, C. (Co-Investigator)
1/01/18 → 8/06/21
Project: Research
Datasets
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A general role for MIA3/TANGO1 in secretory pathway organization and function
Stephens, D. (Creator), McCaughey, J. (Contributor), Mantell, J. (Contributor), Neal, C. R. (Contributor) & Heesom, K. (Contributor), University of Bristol, 20 Jul 2021
DOI: 10.5523/bris.xbao2ekjv5c124o2k0frhq7v6, http://data.bris.ac.uk/data/dataset/xbao2ekjv5c124o2k0frhq7v6
Dataset