Kate J Heesom

2024

Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics

Dulyayangkul, P., Beavis, T., Lee, W. W. Y., Ardagh, R., Edwards, F., Hamilton, F. W., Head, I. M., Heesom, K. J., Mounsey, O. J., Murarik, M. R., Reding, C., Pinweha, P., Satapoomin, N., Shaw, J. M., Takebayashi, Y., Tooke, C. L., Spencer, J., Williams, P. B. & Avison, M. B., 6 Jun 2024, In: PLoS Pathogens. 20, 6, e1012235.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

Improving Nitrofurantoin Resistance Prediction in Escherichia coli from Whole Genome Sequence by Integrating NfsA/B Enzyme Assays

Dulyayangkul, P., Sealey, J. E., Lee, W. W. Y., Satapoomin, A., Reding, C., Heesom, K. J., Williams, P. B. & Avison, M. B., 9 Jul 2024, In: Antimicrobial Agents and Chemotherapy. 68, 7, e00242-24.

Research output: Contribution to journal › Article (Academic Journal)

Open Access

File

25 Downloads (Pure)

Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease

Lay, A. C., Tran, V. D. T., Nair, V., Betin, V. M. S., Hurcombe, J. A., Barrington, A. F., Pope, R. J. P., Burdet, F., Mehl, F., Kryvokhyzha, D., Ahmad, A., C. Sinton, M., Lewis, P., Wilson, M. C., Menon, R., Otto, E. A., Heesom, K. J., C. Looker, H., Nelson, R. G. & Ju, W. & 4 others, Kretzler, M., Satchell, S. C., Lopez-Gomez, M. J. & Coward , R. J. M., 19 Nov 2024, (E-pub ahead of print) In: Nature Communications. 15, 1, 19 p., 10018.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

2 Citations (Scopus)

8 Downloads (Pure)

Roles for CEP170 in cilia function and dynein-2 assembly

Weijman, J. F., Vuolo, L., Shak, C., Pugnetti, A., Mukhopadhyay, A. G., Hodgson, L. R., Heesom, K. J., Roberts, A. J. & Stephens, D. J., 1 May 2024, In: Journal of Cell Science. 137, 8, 12 p., jcs261816.

Research output: Contribution to journal › Article (Academic Journal)

Open Access

Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex

Guo, Q., Chen, K.-E., Gimenez-Andres, M., Jellett, A. P., Gao, Y., Simonetti, B., Liu, M., Danson, C. M., Heesom, K. J., Cullen, P. J. & Collins, B. M., 13 Aug 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 33, p. e2405041121 e2405041121.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

1 Citation (Scopus)

2023

Alterations in platelet proteome signature and impaired platelet integrin α_IIbβ₃ activation in patients with COVID-19

Goudswaard, L., Williams, C. M., Khalil, J. S., Burley, K. L., Hamilton, F. W., Arnold, D. T., Milne, A., Lewis, P., Heesom, K. J., Mundell, S. J., Davidson, A. D., Poole, A. W. & Hers, I., 1 May 2023, In: Journal of Thrombosis and Haemostasis. 21, 5, p. 1307-1321 15 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

11 Citations (Scopus)

Multiple interactions of the dynein-2 complex with the IFT-B complex are required for effective intraflagellar transport

Hiyamizu, S., Qiu, H., Vuolo, L., Stevenson, N. L., Shak, C., Heesom, K. J., Hamada, Y., Tsurumi, Y., Chiba, S., Katoh, Y., Stephens, D. J. & Nakayama, K., 1 Mar 2023, In: Journal of Cell Science. 136, 5, jcs260462.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

11 Citations (Scopus)

Novel human cellular model of CDA IV enables comprehensive analysis revealing molecular basis of disease phenotype

Ferrer Vicens, I., Ferguson, D. C. J., Wilson, M. C., Heesom, K. J., Bieker, J. J. & Frayne, J., 22 Jun 2023, In: Blood. 141, 25, p. 3039-3054 16 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

3 Citations (Scopus)

43 Downloads (Pure)

Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome

Healy, M. D., McNally, K. E., Butkovič, R., Chilton, M., Kato, K., Sacharz, J., McConville, C., Moody, E. R. R., Shaw, S., Planelles-Herrero, V. J., Yadav, S. K. N., Ross, J., Borucu, U., Palmer, C. S., Chen, K.-E., Croll, T. I., Hall, R. J., Caruana, N. J., Ghai, R. & Nguyen, T. H. D. & 9 others, Heesom, K. J., Saitoh, S., Berger, I., Schaffitzel, C., Williams, T. A., Stroud, D. A., Derivery, E., Collins, B. M. & Cullen, P. J., 11 May 2023, In: Cell. 186, 10, p. 2219-2237.e29 49 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

26 Citations (Scopus)

Ultrasound modulates neuronal potassium currents via ionotropic glutamate receptors

Clennell, B., Steward, T. G. J., Hanman, K., Needham, T., Benachour, J. S. F., Jepson, M. A., Elley, M. L., Halford, N., Heesom, K. J., Shin, E., Molnar, E., Drinkwater, B. W. & Whitcomb, D., 1 Mar 2023, In: Brain Stimulation. 16, 2, p. 540-552 13 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

10 Citations (Scopus)

2022

Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function

Trory, J. S., Munkacsi, A., Sledz, K., Goudswaard, L., Jackson, M. L., Heesom, K. J., Moore, S. F., Poole, A. W., Nabet, B., Aggarwal, V. K. & Hers, I., 7 Nov 2022, (E-pub ahead of print) In: Blood Advances.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

3 Citations (Scopus)

Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2

Shak, C., Vuolo, L., Uddin, B., Katoh, Y., Brown, T., Mukhopadhyay, A. G., Heesom, K., Roberts, A. J., Stevenson, N., Nakayama, K. & Stephens, D. J., 7 Nov 2022, In: Journal of Cell Science. 136, 5, jcs260073.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

4 Citations (Scopus)

148 Downloads (Pure)

Effect of cardioplegic arrest and reperfusion on left and right ventricular proteome/phosphoproteome in patients undergoing surgery for coronary or aortic valve disease

Abdul-Ghani, S., Skeffington, K. L., Kim, M., Moscarelli, M., Lewis, P. A., Heesom, K. J., Fiorentino, F., Emanueli, C., Reeves, B. C., Punjabi, P., Angelini, G. D. & Suleiman, M.-S., 14 Apr 2022, (E-pub ahead of print) In: International Journal of Molecular Medicine. 49, 6, 14 p., 77.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

4 Citations (Scopus)

89 Downloads (Pure)

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Simonetti, B., Daly, J., Klein, K., Anton Plagaro, C., Hodgson, L. R., Heesom, K. J., Shoemark, D. K., Davidson, A. D., Yamauchi, Y., Cullen , P. J. & et, A., 21 Jun 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 25, 11 p., 2201980119.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

23 Citations (Scopus)

136 Downloads (Pure)

Exploring platelet proteins altered in severe COVID-19 using gene ontology (GO) pathways

Goudswaard, L., Burley, K. L., Williams, C. M., Heesom, K. J., Mundell, S. J., Poole, A. W. & Hers, I., 2022, (Accepted/In press).

Research output: Contribution to conference › Conference Abstract › peer-review

Green Fluorescent Carbon Dots as Targeting Probes for LED-Dependent Bacterial Killing

Samphire, J. L., Takebayashi, Y., Hill, S. A., Hill, N., Heesom, K. J., Lewis, P. A., Alibhai, D. R., Spencer, J. & Galan, M. C., 1 Mar 2022, In: Nano Select. 3, 3, p. 662-672

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

145 Downloads (Pure)

PDIA3/ERp57 promotes a matrix-rich secretome that stimulates fibroblast adhesion through CCN2

Hellewell, A. L., Heesom, K. J., Jepson, M. A. & Adams, J. C., 1 Apr 2022, In: American journal of physiology. Cell physiology. 322, 4, p. C624–C644 21 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

4 Citations (Scopus)

152 Downloads (Pure)

Penicillanic Acid Sulfones Inactivate the Extended-Spectrum β-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: An Alternative Mechanism of β-Lactamase Inhibition

Hinchliffe, P., Tooke, C. L., Bethel, C. R., Wang, B., Arthur, C., Heesom, K. J., Shapiro, S., Schlatzer, D. M., Papp-Wallace, K. M., Bonomo, R. A. & Spencer, J., 25 May 2022, (E-pub ahead of print) In: mBio. 13, 3, e01793-21.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

6 Citations (Scopus)

120 Downloads (Pure)

Protein disulfide isomerase A3 activity promotes extracellular accumulation of proteins relevant to basal breast cancer outcomes in human MDA-MB-A231 breast cancer cells

Germon, A., Heesom, K. J., Amoah, R. & Adams, J. C., 21 Dec 2022, In: American journal of physiology. Cell physiology. 324, 1, p. C113-C132

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

5 Citations (Scopus)

95 Downloads (Pure)

2021

A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer

Nounu, A., Greenhough, A., Heesom, K. J., Richmond, R. C., Zheng, J., Weinstein, S. J., Albanes, D., Baron, J. A., Melbourne, J. L., Figueiredo, J. C., Newcomb, P. A., Lindor, N. M., Casey, G., Platz, E. A., Le Marchand, L., Ulrich, C. M., Li, C. I., van Duijnhoven, F. J. B., Gsur, A. & Campbell, P. & 42 others, Moreno, V., Vodicka, P., Vodickova, L., Brenner, H., Chang-Claude, J., Hoffmeister, M., Sakoda, L. C., Slattery, M. L., Schoen, R. E., Gunter, M. J., Castellví-Bel, S., Kim, H.-R., Kweon, S.-S., Chan, A. T., Li, L., Zheng, W., Bishop, D. T., Buchanan, D. D., Giles, G. G., Gruber, S. B., Rennert, G., Stadler, Z. K., Harrison, T. A., Lin, Y., Keku, T. O., Woods, M. O., Schafmayer, C., Van Guelpen, B., Gallinger, S., Hampel, H., Berndt, S. I., Pharoah, P. D. P., Lindblom, A., Wolk, A., Wu, A. H., White, E., Peters, U., Drew, D. A., Scherer, D., Bermejo, J. L., Williams, A. C. & Relton, C. L., 1 Mar 2021, In: Cancer Epidemiology, Biomarkers and Prevention.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

12 Citations (Scopus)

81 Downloads (Pure)

A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function

McCaughey, J., Stevenson, N. L., Mantell, J. M., Neal, C. R., Heesom, K. & Stephens, D. J., 7 Sept 2021, In: Journal of Cell Science. 134, 17, jcs259075.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

22 Citations (Scopus)

176 Downloads (Pure)

Arabidopsis thaliana myosin XIK is recruited to the Golgi through interaction with a MyoB receptor

Perico, C., Gao, H., Heesom, K. J., Botchway, S. W. & Sparkes, I. A., 13 Oct 2021, In: Communications Biology. 4, 1, 1182.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

9 Citations (Scopus)

152 Downloads (Pure)

MTAP-related increased erythroblast proliferation as a mechanism of polycythaemia vera

Tipgomut, C., Khuhapinant, A., Wilson, M. C., Poldee, S., Heesom, K. J., Metheetrairut, C., Sripichai, O., Mitrpant, C., Frayne, J. & Trakarnsanga, K., 18 Nov 2021, In: Scientific Reports. 11, 1, 11 p., 22483.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

64 Downloads (Pure)

OmpF Downregulation Mediated by Sigma E or OmpR Activation Confers Cefalexin Resistance in Escherichia coli in the Absence of Acquired β-Lactamases.

Avison, M. B., Dulyayangkul, P., Alzayn, M. M. A., Satapoomin, A. & Heesom, K. J., 18 Oct 2021, (E-pub ahead of print) In: Antimicrobial Agents and Chemotherapy. 65, 11, 25 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

13 Citations (Scopus)

75 Downloads (Pure)

Reduced expression of mitochondrial fumarate hydratase in progressive multiple sclerosis contributes to impaired in vitro mesenchymal stromal cell-mediated neuroprotection

Sarkar, P., Redondo, J., Hares, K. M., Bailey, S., Georgievskaya, A., Heesom, K. J., Kemp, K. C., Scolding, N. J. & Rice, C. M., 29 Nov 2021, (E-pub ahead of print) In: Multiple Sclerosis Journal. 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

3 Citations (Scopus)

280 Downloads (Pure)

SARS-CoV-2 vaccine ChAdOx1 nCoV-19 infection of human cell lines reveals low levels of viral backbone gene transcription alongside very high levels of SARS-CoV-2 S glycoprotein gene transcription

Almuqrin, A., Davidson, A. D., Kavanagh Williamson, M., Lewis, P. A., Heesom, K. J., Morris, S., Gilbert, S. C. & Matthews, D. A., 15 Mar 2021, In: Genome Medicine. 13, 1, 17 p., 43 (2021).

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

38 Citations (Scopus)

150 Downloads (Pure)

Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2

McMillan, K. J., Banks, P. J., Hellel, F. L., Carmichael, R. E., Clairfeuille, T., Evans, A. J., Heesom, K. J., Lewis, P., Collins, B. M., Bashir, Z. I., Henley, J. M., Wilkinson, K. A. & Cullen, P. J., 12 Jul 2021, In: eLife. 10, 32 p., e59432.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

7 Citations (Scopus)

218 Downloads (Pure)

SPARC Matricellular Protein is Enriched in the Bioactive Fraction of the Human Vascular Pericyte Secretome

Avolio, E., Mangialardi, G. M. V. U., Slater, S. C., Alvino, V. V., Gu, Y., Cathery, W. R., Beltrami, A. P., Katare, R. G., Heesom, K. J., Caputo, M. & Madeddu, P. R., 20 May 2021, In: Antioxidants and Redox Signaling.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

13 Citations (Scopus)

398 Downloads (Pure)

Trade-offs between antibacterial resistance and fitness cost in the production of metallo-b-lactamases by enteric bacteria manifest as sporadic emergence of carbapenem resistance in a clinical setting

Phoebe Cheung, C. H., Alorabi, M., Hamilton, F., Takebayashi, Y., Mounsey, O., Heesom, K. J., Williams, P. B., Williams, O. M., Albur, M., MacGowan, A. P. & Avison, M. B., 16 Jul 2021, In: Antimicrobial Agents and Chemotherapy. 65, 8, e02412-20.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

7 Citations (Scopus)

168 Downloads (Pure)

2020

A role for NPY-NPY2R signaling in albuminuric kidney disease

Lay, A. C., Barrington, A. F., Hurcombe, J. A., Ramnath, R. D., Graham, M., Lewis, P. A., Wilson, M. C., Heesom, K. J., Butler, M. J., Perrett, R. M., Neal, C. R., Herbert, E., Mountjoy, E., Atan, D., Nair, V., Ju, W., Nelson, R. G., Kretzler, M., Satchell, S. C. & McArdle, C. A. & 2 others, Welsh, G. I. & Coward, R. J. M., 7 Jul 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 27, p. 15862-15873 12 p., 202004651.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

16 Citations (Scopus)

149 Downloads (Pure)

A small membrane stabilising protein critical to the pathogenicity of Staphylococcus aureus

Duggan, S., Laabei, M., Alnahari, A., O'Brien, E. T., Lacey, K., Bacon, L., Heesom, K. J., Fu, C.-L., Otto, M., Skaar, E., McLoughlin, R. M. & Massey, R. C., 19 Aug 2020, In: Infection and Immunity. 88, 9, 20 p., e00162-20.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

5 Citations (Scopus)

156 Downloads (Pure)

Changes in inflammation and oxidative stress signalling pathways in coarcted aorta triggered by bicuspid aortic valve and growth in young children

Skeffington, K. L., Bond, A. R., Bigotti, M. G., Abdul Ghani, S., Iacobazzi, D., Kang, S., Heesom, K. J., Wilson, M. C., Stoica, S. C., Martin, R., Caputo, M., Suleiman, M.-S. & Ghorbel, M., 3 Sept 2020, In: Experimental and Therapeutic Medicine. 20, 5, p. 48 10 p., 48.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

115 Downloads (Pure)

Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein

Davidson, A. D., Kavanagh Williamson, M., Lewis, S. D., Shoemark, D. K., Carroll, M. W., Heesom, K. J., Zambon, M., Ellis, J., Lewis, P. A., Hiscox, J. A. & Matthews, D. A., 28 Jul 2020, In: Genome Medicine. 12, 15 p., 68.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

261 Citations (Scopus)

235 Downloads (Pure)

Characterization of AmpC-hyperproducing Escherichia coli from humans and dairy farms collected in parallel in the same geographical region

Alzayn, M., Findlay, J., Schubert, H., Mounsey, O., Gould, V. C., Heesom, K. J., Turner, K. M., Barrett, D. C., Reyher, K. K. & Avison, M. B., 1 Sept 2020, In: Journal of Antimicrobial Chemotherapy. 75, 9, p. 2471-2479 9 p., dkaa207.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

16 Citations (Scopus)

102 Downloads (Pure)

Expression of South East Asian Ovalocytic Band 3 Disrupts Erythroblast Cytokinesis and Reticulocyte Maturation

Flatt, J. F., Stevens-Hernandez, C. J., Cogan, N. M., Eggleston, D. J., Haines, N. M., Heesom, K. J., Picard, V., Thomas, C. & Bruce, L. J., 28 Apr 2020, In: Frontiers in Physiology. 11, 357.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

11 Citations (Scopus)

104 Downloads (Pure)

Human adventitial pericytes secrete bioactive factors exerting distinct biological effects on cardiac cells: hints for cardiac repair

Avolio, E., Mangialardi, G. M. V. U., Slater, S. C., Alvino, V. V., Heesom, K. J., Beltrami, A. P., Angelini, G. D. & Madeddu, P. R., 25 Nov 2020, p. 3745. 1 p.

Research output: Contribution to conference › Conference Abstract › peer-review

Open Access

File

67 Downloads (Pure)

Identification of PtdIns(3,4)P₂ effectors in human platelets using quantitative proteomics

Durrant, T. N., Moore, S. F., Bayliss, A. L., Jiang, Y., Aitken, E. W., Wilson, M. C., Heesom, K. J. & Hers, I., 1 Feb 2020, In: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1865, 2, 12 p., 158575.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

File

7 Citations (Scopus)

544 Downloads (Pure)

Identifying the Cellular Interactome of Epstein-Barr Virus Lytic Regulator Zta Reveals Cellular Targets Contributing to Viral Replication

Zhou, Y., Heesom, K., Osborn, K., Almohammad, R., Sweet, S. M. & Sinclair, A. J., 17 Jan 2020, In: Journal of Virology. 13 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

10 Citations (Scopus)

59 Downloads (Pure)

Multi-omic analysis of the effects of low frequency ventilation during cardiopulmonary bypass surgery

Durham, A. L., Al Jaaly, E., Graham, R., Brook, P., Bae, J., Heesom, K. J., Postle, A., Lavender, P., Jazrawi, E., Reeves, B. C., Fiorentino, F., Mumby, S., Angelini, G. D. & Adcock, I. M., 15 Jun 2020, In: International Journal of Cardiology. 309, p. 40-47 8 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

2 Citations (Scopus)

136 Downloads (Pure)

Novel mechanisms of efflux-mediated levofloxacin resistance and reduced amikacin susceptibility in Stenotrophomonas maltophilia

Dulyayangkul, P., Calvopina, K. A., Heesom, K. J. & Avison, M. B., 16 Dec 2020, In: Antimicrobial Agents and Chemotherapy. 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

13 Citations (Scopus)

61 Downloads (Pure)

Proteomic Investigation of the Signal Transduction Pathways Controlling Colistin Resistance in Klebsiella pneumoniae

Phoebe Cheung, C. H., Dulyayangkul, P., Heesom, K. J. & Avison, M. B., 22 Jul 2020, In: Antimicrobial Agents and Chemotherapy.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

5 Citations (Scopus)

83 Downloads (Pure)

TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes

Hook, S. C., Chadt, A., Heesom, K. J., Kishida, S., Al-Hasani, H., Tavaré, J. M. & Thomas, E. C., 21 Oct 2020, In: Scientific Reports. 10, 14 p., 17953 (2020).

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

15 Citations (Scopus)

164 Downloads (Pure)

The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis

Carrat, G., Haythorne, E., Tomas, A., Haataja, L., Muller, A., Arvan, P., Piunti, A., Cheng, K., Huang, M., Pullen, T. J., Georgiadou, E., Stylianides, T., Amirruddin, N. S., Salem, V., Distaso, W., Cakebread, A., Heesom, K. J., Lewis, P. A., Hodson, D. J. & Briant, L. J. B. & 11 others, Fung, A., Sessions, R. B., Alpy, F., Kong, A., Benke, P., Torta, F., Keong Teo, A. K., Leclerc, I., Solimena, M., Wigley, D. & Rutter, G. A., 1 Oct 2020, In: Molecular metabolism. 40, 16 p., 101015.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

20 Citations (Scopus)

152 Downloads (Pure)

Variability in carbapenemase activity of intrinsic OxaAb (OXA-51-like) β-lactamase enzymes in Acinetobacter baumannii

Takebayashi, Y., Findlay, J., Heesom, K. J., Warburton, P., Avison, M. B. & Evans, B. S., 18 Dec 2020, In: Journal of Antimicrobial Chemotherapy. 9 p., dkaa502.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

16 Citations (Scopus)

55 Downloads (Pure)

2019

Bicuspid Aortic Valve Alters Aortic Protein Expression Profile in Neonatal Coarctation Patients

Skeffington, K. L., Bond, A. R., Abdul-Ghani, S., Iacobazzi, D., Kang, S.-L., Heesom, K. J., Wilson, M. C., Ghorbel, M., Stoica, S., Martin, R., Suleiman, M. S. & Caputo, M., 16 Apr 2019, In: Journal of Clinical Medicine. 8, 4, 14 p., 517.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

4 Citations (Scopus)

223 Downloads (Pure)

Characterization of the polarized endothelial secretom

Wei, H., Sundararaman, A., Dickson, E. J., Rennie-Campbell, L., Cross, E., Heesom, K. J. & Mellor, H., 20 Aug 2019, (E-pub ahead of print) In: FASEB Journal. 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

File

22 Citations (Scopus)

392 Downloads (Pure)

LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells

Morgan, R., Ridsdale, J., Payne, M., Heesom, K., Wilson, M. C., Davidson, A., Greenhough, A., Davies, S., Williams, A., Blair, A., Waterman, M. L., Tonks, A. & Darley, R., 1 Jul 2019, In: Haematologica. 104, 7, p. 1365-1377 13 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

38 Citations (Scopus)

515 Downloads (Pure)

Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins

Simonetti, B., Paul, B., Chaudhari, K., Weeratunga, S., Steinberg, F., Gorla, M., Heesom, K. J., Bashaw, G. J., Collins, B. M. & Cullen, P. J., 1 Oct 2019, In: Nature Cell Biology. 21, p. 1219-1233 15 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

80 Citations (Scopus)

118 Downloads (Pure)

Phenotypic proteomic profiling identifies a landscape of targets for circadian clock–modulating compounds

Ray, S., Lach, R., Heesom, K. J., Valekunja, U. K., Encheva, V., Snijders, A. P. & Reddy, A. B., 2 Dec 2019, (E-pub ahead of print) In: Life Science Alliance. 17 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

11 Citations (Scopus)

139 Downloads (Pure)

Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms

Andrew, R. J., Fisher, K., Heesom, K. J., Kellett, K. A. B. & Hooper, N. M., 1 May 2019, In: Journal of Neurochemistry. 149, 3, p. 399-412 14 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

10 Citations (Scopus)

190 Downloads (Pure)

Dr Kate J Heesom

Research output

Search results