Research output per year
Research output per year
Research output
- 1 - 50 out of 455 results
Search results
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2025
Assessing disability progression using the WHODAS 2.0 in multiple sclerosis: investigating clinical and socio-demographic factors in a large longitudinal cohort study (TONiC-MS)
Parker, R. M. A., Tilling, K. M., Mills, R., Tennant, A., Ben-Shlomo, Y., Constantinescu, C., Kalra, S. & Young, C., 1 Jan 2025, In: Multiple Sclerosis and Related Disorders. 93, 9 p., 106228.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
A structural mean modelling Mendelian randomization approach to investigate the lifecourse effect of adiposity: applied and methodological considerations
Power, G. M., Palmer, T. M., Warrington, N. M., Heron, J. E., Richardson, T. G., Didelez, V., Tilling, K. M., Davey Smith, G. & Sanderson, E. C. M., 17 Feb 2025, (E-pub ahead of print) In: American Journal of Epidemiology.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Bidirectional relationships between depression, anxiety and urinary symptoms in women: A prospective cohort study
Joinson, C. J., Drake, M., Fraser, A., Tilling, K. M. & Heron, J. E., 15 Jan 2025, In: Journal of Affective Disorders. 369, p. 516-522 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Life course trajectories of maternal cardiovascular disease risk factors by obstetric history: a UK cohort study using electronic health records
Birnie, K., Howe, L. D., Jones, T., Madley-Dowd, P., Martin, F., Forbes, H. J., Redaniel, M. T., Cornish, R., Magnus, M., Davies, N. M., Tilling, K., Hughes, A. D., Lawlor, D. A. & Fraser, A., 14 Feb 2025, In: BMC Medicine. 23, 1, 17 p., 91.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Lifetime air pollution exposure from prenatal to 18 years and cardiovascular health in young adulthood: findings from a UK birth cohort
Soares, A. G., Tilling, K., Makanvand, M., Kerckhoffs, J., Hansell, A. L., Timpson, N. J. & Elhakeem, A., 21 Feb 2025Research output: Other contribution
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Measuring serious violence perpetration: comparison of police-recorded and self-reported data in a UK cohort
Cornish, R. P., Teyhan, A., Tilling, K. M., Macleod, J. A. A. & Brennan, I., 4 Feb 2025, In: International Journal of Population Data Science. 10, 1, p. 1-3 16 p., 03.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Non-linear mendelian randomization: evaluation of effect modification in the residual and doubly-ranked methods with simulated and empirical examples.
Hamilton, F. W., Hughes, D. A., Lu, T., Kutalik, Z., Gkatzionis, A., Tilling, K. M., Hartwig, F. P. & Davey Smith, G., 21 Jan 2025, (Accepted/In press) In: European Journal of Epidemiology.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Optic disc parameters and associations with early life exposures in over 3000 12-year-old children: findings from the ALSPAC cohort
Creavin, A. L., Tilling, K., Timpson, N. & Williams, C. E., 22 Feb 2025, (E-pub ahead of print) In: Eye. 7 p., 102493.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Relationship between collider bias and interactions on the log-additive scale
Gkatzionis, A., Seaman, S. R., Hughes, R. & Tilling, K. M., 2 Mar 2025, (E-pub ahead of print) In: Statistical Methods in Medical Research.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Downloads (Pure) -
Use of genetic correlations to examine selection bias
Shapland, C. Y., Gkatzionis, A., Hemani, G. & Tilling, K., 1 Feb 2025, In: Genetic Epidemiology. 49, 1, 14 p., e22584.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Using directed acyclic graphs to determine whether multiple imputation or subsample multiple imputation estimates of an exposure-outcome association are unbiased
Madley-Dowd, P. C., Hughes, R., Mathur, M. B., Heron, J. E. & Tilling, K. M., 31 Mar 2025, arXiv.org, (arXiv preprint).Research output: Working paper › Preprint
Open Access -
2024
Accounting for bias due to outcome data missing not at random: Comparison and illustration of two approaches to probabilistic bias analysis: a simulation study
Kawabata, E., Smith, D., Clayton, G. L., Shapland, C. Y., Morris, T. P., Carter, A. R., Fernandez Sanles, A., Borges, M. C., Tilling, K. M., Griffith, G. J., Millard, L. A. C., Davey Smith, G., Lawlor, D. A. & Hughes, R., 21 Oct 2024, (Accepted/In press) In: BMC Medical Research Methodology.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Adiposity and mortality among intensive care patients with COVID-19 and non-COVID-19 respiratory conditions: a cross-context comparison study in the UK
Bell, J. A., Carslake, D., Hughes, A., Tilling, K., Dodd, J. W., Doidge, J. C., Harrison, D. A., Rowan, K. M. & Davey Smith, G., 13 Sept 2024, In: BMC Medicine. 22, 391.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
A framework for conducting GWAS using repeated measures data with an application to childhood BMI
Burrows, K., Heiskala, A., Bradfield, J. P., Balkhiyarova, Z., Ning, L., Boissel, M., Chan, Y.-M., Froguel, P., Bonnefond, A., Hakonarson, H., Alves, A. C., Lawlor, D. A., Kaakinen, M., Järvelin, M.-R., Grant, S. F. A., Tilling, K., Prokopenko, I., Sebert, S., Canouil, M. & Warrington, N. M., 20 Nov 2024, In: Nature Communications. 15, 1, 18 p., 10067.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
A framework for conducting time-varying genome-wide association studies: An application to body mass index across childhood in six multiethnic cohorts
Burrows, K., Heiskala, A., Bradfield, J. P., Balkhiyarova, Z., Ning, L., Boissel, M., Chan, Y.-M., Froguel, P., Bonnefond, A., Hakonarson, H., Alves, A. C., Lawlor, D. A., Kaakinen, M., Järvelin, M.-R., Grant, S. F. A., Tilling, K., Prokopenko, I., Sebert, S., Canouil, M. & Warrington, N. M., 16 Mar 2024, In: medRxiv.Research output: Contribution to journal › Article (Academic Journal)
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A Hypothesis-Free Approach to Identifying Potential Effects of Relative Age in School Year: an Instrumental Variable Phenome-Wide Association Study in the UK Biobank
de Lange, M., Tilling, K. M., Millard, L. A. C. & Davies, N. M., 31 Aug 2024, (E-pub ahead of print) In: American Journal of Epidemiology.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Analyses using multiple imputation need to consider missing data in auxiliary variables
Madley-Dowd, P., Curnow, E., Hughes, R. A., Cornish, R. P., Tilling, K. M. & Heron, J. E., 27 Aug 2024, (E-pub ahead of print) In: American Journal of Epidemiology. kwae306.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
A tool to assess risk of bias in non-randomized follow-up studies of exposure effects (ROBINS-E)
Higgins, J. P. T., Morgan, R. L., Rooney, A. A., Taylor, K. W., Thayer, K. A., Silva, R. A., Lemeris, C., McAleenan, A. S. J., Savović, J., Tilling, K. M., Sterne, J. A. C. & al, E., 24 Mar 2024, (E-pub ahead of print) In: Environment International. 186, 108602.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access153 Citations (Scopus) -
Challenges in using data on fathers/partners to study prenatal exposures and offspring health
Easey, K. E., Gkatzionis, A., Millard, L. A. C., Tilling, K. M., Lawlor, D. A. & Sharp, G. C., 28 Oct 2024, In: Journal of Developmental Origins of Health and Disease. 15, p. e25 9 p., e25.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Counterfactual Mediation Analysis with a Latent Class Exposure
Hammerton, G. L., Heron, J. E., Lewis, K., Tilling, K. M. & Vansteelandt, S., 31 May 2024, (E-pub ahead of print) In: Multivariate Behavioral Research. 59, 4, p. 818-840 23 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Depressive symptoms in adolescence and adult educational and employment outcomes: a structured life course analysis
López-López, J. A., Tilling, K., Pearson, R. M., Fazel, M. S., Washbrook, E., Zhu, Y., Smith, B. J., Dunn, E. C. & Smith, A. D. A. C., 31 May 2024, (E-pub ahead of print) In: Psychological Medicine. 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access3 Citations (Scopus) -
Direct and indirect genetic pathways between parental neuroticism and offspring emotional problems across development: evidence from 7 cohorts across 5 European nations
Sallis, H. M., Costantini, I., Chuong, M., Kantojärvi, K., Wootton, R. E., Jones, H. J., Sirignano, L., Frank, J., Streit, F., Witt, S. H., Zillich, L., Gilles, M., Ask, H., Kwong, A. S. F., Adams, M. J., Tilling, K. M., Lawlor, D. A., Timpson, N. J., Paunio, T. & Havdahl, K. A. & 4 others, , 2024, (Submitted).Research output: Working paper › Preprint
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Emotional problems across development: examining measurement invariance across childhood, adolescence and early adulthood
Riglin, L., Dennison, C. A., Martin, J., Tseliou, F., Armitage, J. M., Shakeshaft, A., Heron, J. E., Tilling, K. M., Thapar, A. & Collishaw, S., 1 Dec 2024, In: European Child and Adolescent Psychiatry. 33, 12, p. 4237-4245 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access2 Citations (Scopus) -
Empirically assessing the plausibility of unconfoundedness in observational studies
Hartwig, F. P., Tilling, K. & Smith, G. D., 15 Feb 2024, 35 p.Research output: Working paper › Preprint
Open AccessFile31 Downloads (Pure) -
Epigenetic Aging and Racialized, Economic, and Environmental Injustice: NIMHD Social Epigenomics Program
Krieger, N., Testa, C., Chen, J. T., Johnson, N., Watkins, S. H., Suderman, M., Simpkin, A. J., Tilling, K., Waterman, P. D., Coull, B. A., De Vivo, I., Smith, G. D., Diez Roux, A. V. & Relton, C., 1 Jul 2024, In: JAMA Network Open. 7, 7, p. e2421832Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access6 Citations (Scopus) -
Estimation of time-varying causal effects with multivariable Mendelian randomization: the importance of model specification.
Sanderson, E. C. M. & Tilling, K. M., 16 Apr 2024, (Accepted/In press) In: International Journal of Epidemiology.Research output: Contribution to journal › Letter (Academic Journal) › peer-review
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Evaluating causal associations of chronotype with pregnancy and perinatal outcomes and its interactions with insomnia and sleep duration: a mendelian randomization study
Yang, Q., Magnus, M. C., Kilpi, F., Santorelli, G., Soares, A. G., West, J., Magnus, P., Håberg, S. E., Tilling, K., Lawlor, D. A., Borges, M. C. & Sanderson, E., 18 Dec 2024, (E-pub ahead of print) In: BMC Pregnancy and Childbirth. 24, 1, 11 p., 816.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Evaluation and comparison of nine growth and development-based measures of pubertal timing
Elhakeem, A., Frysz, M., Goncalves Soares, A., Bell, J. A., Cole, T. J., Heron, J., Howe, L. D., Sebert, S., Tilling, K., Timpson, N. J. & Lawlor, D. A., 7 Aug 2024, In: Communications Medicine. 4, 1, 159.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Investigating the Potential Short-term Adverse Effects of the Quadrivalent Human Papillomavirus Vaccine: A Novel Regression Discontinuity Analysis
Margelyte, R., Redaniel, M. T., Walter, S. R., Pyne, Y., Merriel, S., Macleod, J., Northstone, K. & Tilling, K., 1 Nov 2024, In: Epidemiology. 35, 6, p. 813-822 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Investigation of genetic determinants of cognitive change in later life
Mahedy, L., Anderson, E. L., Tilling, K. M., Thornton, Z., Elmore, A., Szalma, S., Simen, A., Culp, M., Zicha, S., Harel, B., Davey Smith, G., Smith, E. N. & Paternoster, L., 18 Jan 2024, In: Translational Psychiatry. 14, 1, 11 p., 31.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access2 Citations (Scopus) -
Maternal pre-pregnancy body mass index and risk of preterm birth: a collaboration using large routine health datasets
Cornish, R. P., Magnus, M. C., Urhoj, S. K., Santorelli, G., Smithers, L. G., Odd, D., Fraser, A., Haberg, S. E., Nybo Andersen, A.-M., Birnie, K., Lynch, J., Tilling, K. M. & Lawlor, D. A., 5 Jan 2024, In: BMC Medicine. 22, 10, 13 p., 10.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access12 Citations (Scopus) -
Meta-regression of genome-wide association studies to estimate age-varying genetic effects
Pagoni, P., Higgins, J. P. T., Lawlor, D. A., Stergiakouli , E., Warrington, N. M., Morris, T. & Tilling, K. M., 6 Jan 2024, In: European Journal of Epidemiology. 39, 3, p. 257-270 14 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Modeling Risk Factors for Intraindividual Variability: A Mixed-Effects Beta-Binomial Model Applied to Cognitive Function in Older People in the English Longitudinal Study of Ageing
Parker, R. M. A., Tilling, K., Muniz Terrera, G. & Barrett, J. K., 1 Jan 2024, In: American Journal of Epidemiology. 193, 1, p. 159-169 11 p., kwad169.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Multiple imputation strategies for missing event times in a multi-state model analysis
Curnow, E., Hughes, R., Birnie, K., Tilling, K. M. & Crowther, M. J., 22 Feb 2024, In: Statistics in Medicine. 43, 6, p. 1238-1255 18 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Multiple imputation using auxiliary imputation variables that only predict missingness can increase bias due to data missing not at random
Curnow, E., Cornish, R. P., Heron, J. E., Carpenter, J. R. & Tilling, K. M., 7 Oct 2024, In: BMC Medical Research Methodology. 24, 1, 15 p., 231.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Non-linear Mendelian randomization: detection of biases using negative controls with a focus on BMI, Vitamin D and LDL cholesterol
Hamilton, F. W., Hughes, D. A., Spiller, W., Tilling, K. M. & Davey Smith, G., 25 May 2024, (E-pub ahead of print) In: European Journal of Epidemiology. 39, 5, p. 451-465 15 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access15 Citations (Scopus) -
Protein identification for stroke progression via Mendelian Randomization in Million Veteran Program and UK Biobank
Elmore, A., system, V., Hartley, A. E., Aparicio, H. J., Posner, D., Hemani, G., Tilling, K. M., Gaunt, T. R., Wilson, P., Casas, J., Gaziano, J. M., Davey Smith, G., Paternoster, L., Cho, K. & Peloso, G. M., 1 Aug 2024, In: Stroke. 55, 8, p. 2045-2054 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access2 Citations (Scopus) -
The effects of daylight saving time clock changes on accelerometer-measured sleep duration in the UK Biobank
de Lange, M., Birnie, K., Richmond, R., Tilling, K. M., Shapland, C. Y. & Davies, N. M., 27 Aug 2024, p. A77-A78. 2 p.Research output: Contribution to conference › Conference Abstract › peer-review
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The effects of daylight saving time clock changes on accelerometer-measured sleep duration in the UK Biobank
de Lange, M., Richmond, R., Birnie, K., Shapland, C. Y., Tilling, K. M. & Davies, N., 21 Oct 2024, (E-pub ahead of print) In: Journal of Sleep Research. e14335.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
The effects of daylight saving time clock changes on accelerometer-measured sleep duration in the UK Biobank
de Lange, M., Richmond, R., Birnie, K., Shapland, C. Y., Tilling, K. M. & Davies, N. M., 22 Sept 2024.Research output: Contribution to conference › Conference Abstract
Open AccessFile9 Downloads (Pure) -
The impact of targeted local outreach clinics to improve COVID-19 vaccine uptake: controlled interrupted time series in South West England
Jones, T., Adamali, H., Redaniel, M. T., de Vocht , F., Tilling, K. M., Kenward, C., Ben-Shlomo, Y. & Creavin, S. T., 7 Aug 2024, (E-pub ahead of print) In: Archives of Public Health. 82, 1, 13 p., 118.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Two sample Mendelian Randomisation using an outcome from a multilevel model of disease progression
Lawton, M. A., Ben-Shlomo, Y., Gkatzionis, A., Hu, M. T. M., Grosset, D. G. & Tilling, K. M., 1 May 2024, In: European Journal of Epidemiology. 39, 5, p. 521-533 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Using Instruments for Selection to Adjust for Selection Bias in Mendelian Randomization
Gkatzionis, A., Tchetgen Tchetgen, E. J., Heron, J. E., Northstone, K. & Tilling, K. M., 30 Sept 2024, In: Statistics in Medicine. 43, 22, p. 4250-4271 22 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access2 Citations (Scopus) -
Using the global randomization test as a Mendelian randomization falsification test for the exclusion restriction assumption
Millard, L. A. C., Davey Smith, G. & Tilling, K. M., 29 Feb 2024, In: European Journal of Epidemiology. 39, 8, p. 843-855 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access3 Citations (Scopus) -
Young Adult ADHD Symptoms in the General Population and Neurocognitive Impairment
Agha, S. S., Riglin, L., Carbury, R., Blakey, R., Shakeshaft, A., Thapar, A. K., Tilling, K., Collishaw, S., Stergiakouli, E., Thapar, A. & Langley, K., 1 Jan 2024, In: Journal of attention disorders. 28, 1, p. 89-98 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
2023
A framework for assessing selection and misclassification bias in mendelian randomisation studies: an illustrative example between body mass index and covid-19
Clayton, G. L., Goncalves Soares, A., Goulding, N. J., Borges, M. C., Holmes, M. V., Davey Smith, G., Tilling, K. M., Lawlor, D. A. & Carter, A. R., 19 Jun 2023, In: BMJ. 381, e072148.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access16 Citations (Scopus) -
Association between inflammation and cognition: triangulation of evidence using a population-based cohort and Mendelian randomization analyses
Slaney, C., Sallis, H. M., Jones, H. J., Dardani, C., Inflammation Working Group, C., Tilling, K., Munafò, M. R., Davey Smith, G., Mahedy, L. & Khandaker, G. M., 1 May 2023, In: Brain, Behavior, and Immunity. 110, p. 30-42 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access15 Citations (Scopus) -
Association between perinatal mortality and morbidity and customised and non-customised birthweight centiles in Denmark, Finland, Norway, Wales, and England: comparative, population based, record linkage study
Kilpi, F. C., Jones, H. E., Magnus, M., Santorelli, G., Hojsgaard Schmidt, L., Kjaer Urhoj, S., Nelson, S., Tuffnell, D., French, R., Magnus, P. M., Nybo Andersen, A.-M., Martikainen, P., Tilling, K. M. & Lawlor, D. A., 30 Aug 2023, In: BMJ Medicine. 2, 1, e000521.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Characterising patterns of COVID-19 and long COVID symptoms: evidence from nine UK longitudinal studies
the CONVALESCENCE Study, Bowyer, R. C. E., Huggins, C., Toms, R., Shaw, R. J., Hou, B., Thompson, E. J., Kwong, A. S. F., Williams, D. M., Kibble, M., Ploubidis, G. B., Timpson, N. J., Sterne, J. A. C., Chaturvedi, N., Steves, C. J., Tilling, K. & Silverwood, R. J., 1 Feb 2023, In: European Journal of Epidemiology. 38, 2, p. 199-210 12 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access21 Citations (Scopus) -
Childhood Attention Deficit Hyperactivity Disorder problems and mid-life cardiovascular risk: Prospective population cohort study
Thapar, A., Riglin, L., Blakey, R., Collishaw, S., Davey Smith, G., Stergiakouli , E., Tilling, K. M. & Thapar, A., 1 Oct 2023, In: British Journal of Psychiatry. 223, 4, p. 472-477 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access9 Citations (Scopus)