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Research Output

2020

ADHD and depression: investigating a causal explanation

Riglin, L., Leppert, B., Dardani, C., Thapar, A., Rice, F., O'Donovan, M. C., Davey Smith, G., Stergiakouli, E., Tilling, K. M. & Thapar, A., 6 Apr 2020, In : Psychological Medicine. p. 1 - 8 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Improved two-stage estimation to adjust for treatment switching in randomised trials: g-estimation to address time-dependent confounding

Latimer, N., White, IR., Tilling, K. M. & Siebert, U., 30 Mar 2020, In : Statistical Methods in Medical Research. 19 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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13 Downloads (Pure)
Open Access
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32 Downloads (Pure)
Open Access
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42 Downloads (Pure)
2019

Accounting for missing data in statistical analyses: multiple imputation is not always the answer

Hughes, R. A., Heron, J., Sterne, J. A. C. & Tilling, K., 1 Aug 2019, In : International Journal of Epidemiology. 48, 4, p. 1294-1304 11 p., dyz032.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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23 Citations (Scopus)
373 Downloads (Pure)

A discussion of statistical methods to characterise early growth and its impact on bone mineral content later in childhood

Crozier, S. R., Johnson, W., Cole, T. J., Macdonald-Wallis, C., Muniz-Terrera, G., Inskip, H. M. & Tilling, K., 15 Apr 2019, In : Annals of Human Biology. 46, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1 Citation (Scopus)
27 Downloads (Pure)

Analysis of 'sensitive' periods of fetal and child growth

Zhang, X., Tilling, K., Martin, R., Oken, E., Naimi, A., Aris, I., Yang, S. & Kramer, M. S., 1 Feb 2019, In : International Journal of Epidemiology. 48, 1, p. 116-123 8 p., dyy045.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
132 Downloads (Pure)

Association Between Age at Puberty and Bone Accrual From 10 to 25 Years of Age

Elhakeem, A., Frysz, M., Tilling, K., Tobias, J. & Lawlor, D., 9 Aug 2019, In : JAMA Network Open. 2, 8, 14 p., e198918.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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108 Downloads (Pure)

Association of Maternal Neurodevelopmental Risk Alleles With Early-Life Exposures

Leppert, B., Havdahl, K. A., Riglin, L., Jones, H., Zheng, J., Davey Smith, G., Tilling, K., Thapar, A., Reichborn-Kjennerud, T. & Stergiakouli, E., 1 May 2019, In : JAMA Psychiatry. 76, 8, p. 834-842 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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291 Downloads (Pure)

Associations of maternal quitting, reducing and continuing smoking during pregnancy on longitudinal fetal growth: evidence from Mendelian randomization and parental negative control studies

Brand, J. S., Gaillard, R., West, J., McEachan, R. R. C., Wright, J., Voerman, E., Felix, J. F., Tilling, K. & Lawlor, D., 13 Nov 2019, In : PLoS Medicine. 16, 11, 24 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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69 Downloads (Pure)

Conditioning on a mediator

Groenwold, R., Palmer, T. & Tilling, K. M., 23 Dec 2019, OSF Preprints.

Research output: Working paperWorking paper and Preprints

Data on trajectories of measures of cardiovascular health in the Avon Longitudinal Study of Parents and Children (ALSPAC)

O'Keeffe, L., Simpkin, A., Tilling, K., Anderson, E., Hughes, A. D., Lawlor, D., Fraser, A. & Howe, L., 1 Apr 2019, In : Data in Brief. 23, 16 p., 103687.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
163 Downloads (Pure)

Duration of untreated psychosis and clinical outcomes of first episode psychosis: An observational and an instrumental variables analysis

Sullivan, S., Carroll, R., Peters, TJ., Amos, T., Jones, P. B., Marshall, M., Birchwood, M., Fowler, D., Johnson, S., Fisher, H. L., Major, B., Rahaman, N., Joyce, J., Chamberlain-Kent, N., Lawrence, J., Moran, P. & Tilling, K., 1 Aug 2019, In : Early Intervention in Psychiatry. 13, 4, p. 841-847 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
163 Downloads (Pure)

Forecasting the 2021 local burden of population alcohol-related harms using Bayesian structural time-series

McQuire, C., Tilling, K., Hickman, M. & De Vocht, F., 1 Jun 2019, In : Addiction. 114, 6, p. 994-1003 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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273 Downloads (Pure)
Open Access
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3 Citations (Scopus)
138 Downloads (Pure)
Open Access
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221 Downloads (Pure)

Identifying novel types of irritability using a developmental genetic approach

Riglin, L., Eyre, O., Thapar, A., Stringaris, A., Leibenluf, E., Pine, D. S., Tilling, K., Davey Smith, G., O'Donovan, M. C. & Thapar, A., 1 Jul 2019, In : American Journal of Psychiatry. 176, 8, p. 635-642 8 p.

Research output: Contribution to journalArticle (Academic Journal)

1 Downloads (Pure)

Is screen time associated with anxiety or depression in young people? Results from a UK birth cohort

Khouja, J., Munafo, M., Tilling, K., Wiles, N., Joinson, C., Etchells, P., John, A., Hayes, F., Gage, S. & Cornish, R., 17 Jan 2019, In : BMC Public Health. 19, 1, p. 82 11 p., 82.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
281 Downloads (Pure)

Is teachers’ mental health and wellbeing associated with students’ mental health and wellbeing?

Harding, S., Evans, R., Morris, R., Gunnell, D., Ford, T., Hollingworth, W., Tilling, K., Bell, S., Grey, J., Brockman, R., Campbell, R., Araya, R., Murphy, S. & Kidger, J., Jan 2019, In : Journal of Affective Disorders. 242, p. 180-187 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
189 Downloads (Pure)

Live-birth rates and perinatal outcomes when all embryos are frozen compared with conventional fresh- and frozen-embryo transfer: a cohort study of 337,148 in-vitro fertilisation cycles

Smith, A. D. A. C., Tilling, K., Lawlor, D. A. & Nelson, S. M., 13 Nov 2019, In : BMC Medicine. 17, 13 p., 202 (2019) .

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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99 Downloads (Pure)

Methods for Dealing with Missing Covariate Data in Epigenome-Wide Association Studies

Mills, H., Heron, J., Relton, C., Suderman, M. & Tilling, K., 5 Sep 2019, In : American Journal of Epidemiology. 23 p., kwz186.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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88 Downloads (Pure)
Open Access
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84 Downloads (Pure)

Predictors of future suicide attempt among adolescents with suicidal thoughts or non-suicidal self-harm: a population-based birth cohort study

Mars, B., Heron, J., Klonsky, E. D., Moran, P., O'Connor, R. C., Tilling, K., Wilkinson, P. & Gunnell, D., 1 Apr 2019, In : The Lancet Psychiatry. 6, 4, p. 327-337 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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22 Citations (Scopus)
254 Downloads (Pure)

RoB 2: a revised tool for assessing risk of bias in randomised trials

Sterne, J. A. C., Savović, J., Page, M. J., Elbers, R. G., Blencowe, N. S., Boutron, I., Cates, C. J., Cheng, H-Y., Corbett, M. S., Eldridge, S. M., Emberson, J. R., Hernán, M. A., Hopewell, S., Hróbjartsson, A., Junqueira, D. R., Juni, P., Kirkham, J. J., Lasserson, T., Li, T., McAleenan, A. & 8 others, Reeves, B. C., Shepperd, S., Shrier, I., Stewart, L. A., Tilling, K., White, I. R., Whiting, P. F. & Higgins, J. P. T., 28 Aug 2019, In : BMJ. 366, 8 p., l4898.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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183 Downloads (Pure)
Open Access
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211 Downloads (Pure)

Selection bias when estimating average treatment effects using one-sample instrumental variable analysis

Hughes, R. A., Davies, N. M., Davey Smith, G. & Tilling, K., 1 May 2019, In : Epidemiology. 30, 3, p. 350-357 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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7 Citations (Scopus)
176 Downloads (Pure)

Smoking, DNA methylation and lung function: a Mendelian randomization analysis to investigate causal relationships

Jamieson, E., Korogolou-Linden, R., Wootton, R., Guyatt, A., Battram, T., Burrows, K., Gaunt, T., Tobin, M., Munafo, M., Davey, S. G., Tilling, K., Relton, C. & Richmond, R., Aug 2019, (Submitted) bioRxiv.org.

Research output: Working paperWorking paper and Preprints

The effect of a lifestyle intervention in obese pregnant women on gestational metabolic profiles: Findings from the UK Pregnancies Better Eating and Activity Trial (UPBEAT) randomised controlled trial

Mills, H. L., Patel, N., White, S. L., Pasupathy, D., Briley, A. L., Dos Santos Ferreira, D. L., Seed, P. T., Nelson, S. M., Sattar, N., Tilling, K., Poston, L., Lawlor, D. A. & On behalf of the UPBEAT Consortium, 21 Jan 2019, In : BMC Medicine. 17, 15, 12 p., 15.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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6 Citations (Scopus)
231 Downloads (Pure)

The proportion of missing data should not be used to guide decisions on multiple imputation

Madley-Dowd, P., Hughes, R., Tilling, K. & Heron, J., 13 Jun 2019, In : Journal of Clinical Epidemiology. 110, p. 63-73 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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20 Citations (Scopus)
325 Downloads (Pure)

The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation

Rooshenas, L., By-Band-Sleeve study group, CSAW study group, HAND-1 study group, OPTIMA prelim study group, the Romio feasibility study group, Scott, L. J., Blazeby, J. M., Rogers, C. A., Tilling, K. M., Husbands, S., Conefrey, C., Mills, N., Metcalfe, C., Carr, A. J., Beard, D., Davis, T., Paramasivan, S., Jepson, M., Avery, K. & 4 others, Elliott, D., Wilson, C. A., Donovan, J. L. & Macpherson, I. E., 1 Feb 2019, In : Journal of Clinical Epidemiology. 106, p. 108-120 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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10 Citations (Scopus)
262 Downloads (Pure)

The second generation of The Avon Longitudinal Study of Parents and Children (ALSPAC-G2): a cohort profile

Lawlor, D., Lewcock, M., Jones, L., Rollings, C., Yip, V., Smith, D., Pearson, R., Johnson, L., Millard, L., Patel, N., Skinner, A. & Tilling, K., 21 Feb 2019, In : Wellcome Open Research. 4, 36, 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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251 Downloads (Pure)

Trajectories of depressive symptoms and adult educational and employment outcomes

Lopez-Lopez, J., Kwong, A. S. F., Washbrook, E. V., Pearson, R. M., Tilling, K. M., Fazel, M., Kidger, J. L. & Hammerton, G., 12 Dec 2019, In : BJPsych Open. 6, 1, 8 p., e6.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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117 Downloads (Pure)

Transition to parenthood and mental health at 30 years: a prospective comparison of mothers and fathers in a large Brazilian birth cohort

Pearson, R. M., Culpin, I., Loret de Mola, C., Quevedo, L., Murray, J., Matijasevich, A., Tilling, K., Barros, F. C., Stein, A. & Horta, B. L., 1 Oct 2019, In : Archives of Women's Mental Health. 22, 5, p. 621-629 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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172 Downloads (Pure)
1 Citation (Scopus)

Using genetics to examine a general liability to childhood psychopathology

Riglin, L., Thapar, A., Leppert, B., Martin, J., Richards, A., Anney, R., Davey Smith, G., Tilling, K. M., Stergiakouli, E., Lahey, B., O'Donovan, M. C., Collishaw, S. & Thapar, A., 11 Dec 2019, In : Behavior Genetics. 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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111 Downloads (Pure)

What distinguishes adolescents with suicidal thoughts from those who have attempted suicide? A population-based birth cohort study

Mars, B., Heron, J., Klonsky, E. D., Moran, P., O'Connor, R. C., Tilling, K., Wilkinson, P. & Gunnell, D., Jan 2019, In : Journal of Child Psychology and Psychiatry. 60, 1, p. 91-99 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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28 Citations (Scopus)
253 Downloads (Pure)
2018
Open Access
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1 Citation (Scopus)
226 Downloads (Pure)

Adverse childhood experiences in the children of the Avon Longitudinal Study of Parents and Children (ALSPAC)

Houtepen, L., Heron, J., Suderman, M., Tilling, K. & Howe, L., 30 Aug 2018, In : Wellcome Open Research. 3, 15 p., 106.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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6 Citations (Scopus)
218 Downloads (Pure)
Open Access
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235 Downloads (Pure)

Association of Height Growth in Puberty with Lung Function: A Longitudinal Study

Mahmoud, O., Granell, R., Tilling, K., Minelli, C., Garcia-Aymerich, J., Holloway, J. W., Custovic, A., Jarvis, D., Sterne, J. & Henderson, J., 15 Dec 2018, In : American Journal of Respiratory and Critical Care Medicine. 198, 12, p. 1539-1548 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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11 Citations (Scopus)
231 Downloads (Pure)

Association of Primary Care Consultation Patterns With Early Signs and Symptoms of Psychosis

Sullivan, S., Hamilton, W., Tilling, K., Redaniel, T., Moran, P. & Lewis, G. H., Nov 2018, In : JAMA Network Open. 1, 7, 26 p., e185174.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
192 Downloads (Pure)

Associations of sex hormone-binding globulin and testosterone with genome-wide DNA methylation

Arathimos, R., Sharp, G., Granell, R., Tilling, K. & Relton, C., 14 Dec 2018, In : BMC Genetics. 19, 11 p., 113.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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181 Downloads (Pure)
Open Access
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13 Citations (Scopus)
120 Downloads (Pure)

Childhood sleep and adolescent chronic fatigue syndrome (CFS/ME): evidence of associations in a UK birth cohort

Collin, S., Norris, T., Gringras, P., Blair, P., Tilling, K. & Crawley, E., Jun 2018, In : Sleep Medicine. 46, p. 26-36 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
315 Downloads (Pure)

Collider scope: when selection bias can substantially influence observed associations

Munafò, M. R., Tilling, K., Taylor, A. E., Evans, D. M. & Davey Smith, G., 1 Feb 2018, In : International Journal of Epidemiology. 47, 1, p. 226-235 10 p., dyx217.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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122 Citations (Scopus)
436 Downloads (Pure)

Correction to: The impact of parity on life course blood pressure trajectories: the HUNT study in Norway

Haug, E. B., Horn, J., Markovitz, A. R., Fraser, A., Macdonald-Wallis, C., Tilling, K., Romundstad, P. R., Rich-Edwards, J. W. & Åsvold, B. O., 6 Jul 2018, In : European Journal of Epidemiology. 1 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1 Citation (Scopus)
194 Downloads (Pure)

Derivative estimation for longitudinal data analysis: Examining features of blood pressure measured repeatedly during pregnancy

Simpkin, A. J., Durban, M., Lawlor, D. A., MacDonald-Wallis, C., May, M. T., Metcalfe, C. & Tilling, K., 30 Aug 2018, In : Statistics in Medicine. 37, 19, p. 2836-2854 19 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
239 Downloads (Pure)