Research output per year
Research output per year
Personal profile
Research interests
Katie Pike is a medical statistician, working within the UKCRC registered Bristol Trials Centre. She is involved in the design, conduct and analysis of randomised controlled trials (RCTs) and is a statistical co-applicant on a number of projects. She has experience in RCTs in a variety of clinical areas including cardiac surgery, ophthalmology, orthopaedics, pain management, emergency medicine and bariatric surgery. Her main interests lie in large, pragmatic RCTs and addressing methodological challenges that arise.
Her PhD was undertaken via an NIHR doctoral fellowship and was titled “Design and analysis of randomised controlled trials not seeking marketing authorisation: when and how to adjust for multiplicity”. She performed systematic reviews and a survey of triallists, undertook simulation work to compare methods used to address multiplicity, developed recommendations for handling multiplicity, and finally produced a trial design tool to calculate sample sizes in trials where multiplicity issues arise.
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Collaborations and top research areas from the last five years
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Research output
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Roux-en-Y gastric bypass, adjustable gastric banding, or sleeve gastrectomy for severe obesity (By-Band-Sleeve): a multicentre, open label, three-group, randomised controlled trial
The By-Band-Sleeve Collaborative Group, Blazeby, J., Agrawal, S., Ahmed, A., Andrews, R., Blencowe, N. S., Byrne, J., Carter, N., Chalmers, K. A., Cousins, S. E., Coulman, K. D., Culliford, L., Dabner, L. S., Davies, N., Donovan , J. L., Edwards, D. K., Evans, R. N., Fermont, J. M., Finlay, I. & Gidman, E. A. & 23 others, , 1 May 2025, In: Lancet Diabetes and Endocrinology. 13, 5, p. 410-426 17 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access2 Citations (Scopus) -
The ZosterFluCov Study Statistical Analysis Plan v4.0
Harris, R. A., Pike, K. E. & Lazarus, R., 29 Nov 2025, (Unpublished) 27 p. University of Bristol.Research output: Other contribution
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Adalimumab vs placebo as add-on to Standard Therapy for autoimmune Uveitis: Tolerability, Effectiveness and cost-effectiveness-a protocol for a randomised controlled trial (ASTUTE trial)
Hazell, M., Reeves, B., CA, R., Pike, K., Culliford, L., Baos, S., MPY, L., NAV, B., Pavesio, C., AK, D., Wordsworth, S., PA, K., Wilson, R., Folkard, A., Peto, T., Sharma, S. M. & Dick, A., 24 Jan 2024, In: BMJ Open. 14, 1, e082246.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access
Thesis
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Design and analysis of randomised controlled trials not seeking marketing authorisation: when and how to adjust for multiplicity
Pike, K. E. (Author), Rogers, C. A. (Supervisor) & Reeves, B. C. (Supervisor), 18 Mar 2025Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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