Dr Katy A Chalmers

BSc (Hons), Ph.D(Bristol)

  • BS8 2PS

20032020

Research output per year

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Research Output

  • 32 Article (Academic Journal)
  • 3 Conference Contribution (Conference Proceeding)
  • 1 Review article (Academic Journal)
2020

A real-time electronic symptom monitoring system for patients after discharge following surgery: a pilot study in cancer-related surgery

Richards, H. S., Blazeby, J. M., Portal, A., Harding, R., Reed, T., Lander, T., Chalmers, K. A., Carter, R., Absolom, K., Singhal, R., Velikova, G. & Avery, K. N. L., 10 Jun 2020, In : BMC Cancer. 20, 17 p., 543 (2020).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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12 Downloads (Pure)

Optimizing the design of invasive placebo interventions in randomized controlled trials

Cousins, S., Blencowe, N. S., Tsang, C., Chalmers, K., Mardanpour, A., Carr, A. J., Campbell, M. K., Cook, J. A., Beard, D. J. & Blazeby, J. M., 18 Mar 2020, In : British Journal of Surgery. 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
23 Downloads (Pure)

Reporting of key methodological issues in placebo-controlled trials of surgery needs improvement: a systematic review

Cousins, S., Blencowe, N. S., Tsang, C., Lorenc, A., Chalmers, K., Carr, A. J., Campbell, M. K., Cook, J. A., Beard, D. J. & Blazeby, J. M., 1 Mar 2020, In : Journal of Clinical Epidemiology. 119, p. 109-116 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
70 Downloads (Pure)
2019

Impact on health-related quality of life of video-assisted thoracoscopic surgery for lung cancer: A prospective study in patients with non-small cell lung cancer

Avery, K. N. L., Blazeby, J. M., Chalmers, K. A., Batchelor, T. J. P., Casali, G., Internullo, E., Krishnadas, R., Evans, C. & West, D., 1 Dec 2019, In : Annals of Surgical Oncology. 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
79 Downloads (Pure)

Laparoscopically assisted vs open oesophagectomy for patients with oesophageal cancer – the ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open) study: protocol for a randomized controlled trial (RCT)

Brierley, R. C. M., Gaunt, D. M., Metcalfe, C., Blazeby, J. M., Blencowe, N. S., Jepson, M., Berrisford, R., Avery, K. N. L., Hollingworth, W., Rice, C., Moure Fernandez, A., Wong, N. A. C. S., Nicklin, J. K., Skilton, A., Boddy, A. P., Byrne, J., Underwood, T., Vohra, R. S., Catton, J. A., Pursnani, K. & 47 others, Melhado, R., Alkhaffaf, B., Krysztopik, R., Lamb, P., Culliford, L. A., Rogers, C. A., Howes, B., Chalmers, K. A., Cousins, S. E., Elliott, J., Donovan, J. L., Heys, R. L., Wickens, R. A., Wilkeron, P., Hollowood, A., Streets, C. G., Titcomb, D. R., Humphreys, M. L., Wheatley, T., Sanders, G., Ariyarathenam, A., Kelly, J., Noble, F., Couper, G., Skipworth, R. J. E., Deans, C., Ubhi, S., Williams, R., Bowrey, D., Exon, D., Turner, P., Shetty, V., Chaparala, R., Akhtar, K., Farooq, N., Parsons, S., Welch, N., Houlihan, R., Smith, J., Schranz, R., Rea, N., Cooke, J., Williams, A., Hindmarsh, C., Maitland, S., Howie, L. & Barham, C. P., 19 Nov 2019, In : BMJ Open. 9, 8 p., e030907.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
20 Downloads (Pure)

Optimising the design of invasive placebo interventions in randomised controlled trials

Cousins, S. E., Blencowe, N. S., Tsang, C., Chalmers, K. A., Mardanpour, A., Carr, A., Campbell, M. K., Cook, J., Beard, D. & Blazeby, J. M., 13 Dec 2019, (Accepted/In press) In : British Journal of Surgery.

Research output: Contribution to journalArticle (Academic Journal)

2018

Development of a Core Outcome Set for Clinical Effectiveness Trials in Esophageal Cancer Resection Surgery

Avery, K. N. L., Chalmers, K. A., Brookes, S. T., Blencowe, N. S., Coulman, K., Whale, K., Metcalfe, C., Blazeby, J. M. & the ROMIO Study Group, Apr 2018, In : Annals of Surgery. 267, 4, p. 700-710 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
13 Citations (Scopus)
335 Downloads (Pure)

Impact of question order on prioritisation of outcomes in the development of a core outcome set: A randomised controlled trial

Brookes, S. T., Chalmers, K. A., Avery, K. N. L., Coulman, K., Blazeby, J. M. & on behalf of the ROMIO study group, 25 Jan 2018, In : Trials. 19, 11 p., 66.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
222 Downloads (Pure)
2017

Methodological overview of systematic reviews to establish the evidence base for emergency general surgery

Savović, J., Blencowe, N., Strong, S., Howes, N., Chalmers, K., Chrichton, J., Gould, L., Kariyawasam, S., Mason, J., Pegna, V., Richards, S., Rowlands, C., Stevens, D., Whale, K. & Blazeby, J., 14 Mar 2017, In : British Journal of Surgery. 104, 5, p. 513-524 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
475 Downloads (Pure)
2016

A Comparison of Health Professionals’ and Patients’ Views of the Importance of Outcomes of Bariatric Surgery

Coulman, K., Howes, N., Hopkins, J., Whale, K., Chalmers, K., Brookes, S., Nicholson, A., Savovic, J., Ferguson, Y., Owen-Smith, A., Blazeby, J. & The By-Band-Sleeve Trial Management Group, Nov 2016, In : Obesity Surgery. 26, 11, p. 2738-2746 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
22 Citations (Scopus)
234 Downloads (Pure)

A Core Outcome Set for the Benefits and Adverse Events of Bariatric and Metabolic Surgery: the BARIACT project

Coulman, K., Hopkins, J., Brookes, S., Chalmers, K., Main, B., Owen-Smith, A., Andrews, R., Byrne, J., Donovan, J., Mazza, G., Reeves, B., Rogers, C., Thompson, J. L., Welbourn, R., Wordsworth, S. & Blazeby, J., 29 Nov 2016, In : PLoS Medicine. 13, 11, e1002187.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
22 Citations (Scopus)
272 Downloads (Pure)
2015

Erratum: Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue

Love, S., Chalmers, K., Ince, P., Esiri, M., Attems, J., Kalaria, R., Jellinger, K., Yamada, M., McCarron, M., Minett, T., Matthews, F., Greenberg, S., Mann, D. & Kehoe, P. G., 30 Dec 2015, In : American Journal of Neurodegenerative Disease. 4, 2, p. 49

Research output: Contribution to journalArticle (Academic Journal)

Regional Increase in the Expression of the BCAT Proteins in Alzheimer's Disease Brain: Implications in Glutamate Toxicity

Hull, J., Patel, V., El Hindy, M., Lee, C., Odeleye, E., Hezwani, M., Love, S., Kehoe, P., Chalmers, K. & Conway, M., 29 Jan 2015, In : Journal of Alzheimer's Disease.

Research output: Contribution to journalArticle (Academic Journal)

14 Citations (Scopus)

What are important outcomes of bariatric surgery? An in-depth analysis to inform the development of a core outcome set and a comparison between the views of surgeons and other health professionals (the BARIACT study)

Hopkins, J., Howes, N., Chalmers, K., Whale, K., Savovic, J., Coulman, K., Nicholson, A., Byrne, J., Whistance, R., Welbourn, R., Andrews, R., Blazeby, J. & By-Band Trial Management Group, 26 Feb 2015, In : Lancet. 385 Suppl 1, p. S43

Research output: Contribution to journalArticle (Academic Journal)

2014

Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue

Love, S., Chalmers, K., Ince, P., Esiri, M., Attems, J., Jellinger, K., Yamada, M., McCarron, M., Minett, T., Matthews, F., Greenberg, S., Mann, D. & Kehoe, P. G., 2014, In : American Journal of Neurodegenerative Disease. 3, 1, p. 19-32 14 p.

Research output: Contribution to journalArticle (Academic Journal)

62 Citations (Scopus)

THE PATIENT PERSPECTIVE OF BARIATRIC SURGERY OUTCOMES: DEVELOPING A 'CORE' SET OF PATIENT-REPORTED OUTCOMES

Coulman, K. D., Owen-Smith, A., Andrews, R. C., Chalmers, K., Ferguson, Y., Norton, S., Welbourn, R., Whale, K. & Blazeby, J. M., Aug 2014, Obesity Surgery. Vol. 24. p. 1296-1296 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

2012

Distribution of the branched chain aminotransferase proteins in the human brain and their role in glutamate regulation

Hull, J., El Hindy, M., Kehoe, P. G., Chalmers, K., Love, S. & Conway, M. E., Dec 2012, In : Journal of Neurochemistry. 123, 6, p. 997-1009 13 p.

Research output: Contribution to journalArticle (Academic Journal)

36 Citations (Scopus)
2010

LRP-1 variation is not associated with risk of Alzheimer's disease

Chalmers, K. A., Barker, R., Passmore, P. A., Panza, F., Seripa, D., Solfrizzi, V., Love, S., Prince, J. A. & Kehoe, P. G., 21 Jul 2010, In : International Journal of Molecular Epidemiology. 1, 2, p. 104-113 10 p.

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)
2009

Cholinesterase inhibitors may increase phosphorylated tau in Alzheimer's disease

Chalmers, KA., Wilcock, GK., Vinters, HV., Perry, EK., Perry, R., Ballard, CG. & Love, S., May 2009, In : Journal of Neurology. 256, p. 717 - 720 4 p.

Research output: Contribution to journalArticle (Academic Journal)

21 Citations (Scopus)

Insights into the pathogenesis and pathogenicity of cerebral amyloid angiopathy

Love, S., Miners, JS., Palmer, JC., Chalmers, KA. & Kehoe, PG., Jan 2009, In : Frontiers in Bioscience. 14, p. 4778 - 4792 15 p.

Research output: Contribution to journalReview article (Academic Journal)

52 Citations (Scopus)

TNFR-associated factor-2 (TRAF-2) in Alzheimer's disease

Culpan, D., Cram, D., Chalmers, K. A., Cornish, A., Palmer, L., Palmer, J., Hughes, A., Passmore, P., Craig, D., Craigs, D., Wilcock, G. K., Kehoe, P. G. & Love, S., Jul 2009, In : Neurobiology of Aging. 30, 7, p. 1052 - 1060 9 p.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)
2008

Angiotensin-converting enzyme (ACE) levels and activity in Alzheimer's disease, and relationship of perivascular ACE-1 to cerebral amyloid angiopathy

Miners, JS., Ashby, EL., van Helmond, Z., Chalmers, KA., Palmer, LE., Love, S. & Kehoe, PG., Apr 2008, In : Neuropathology and Applied Neurobiology. 34 , 2, p. 181 - 193 13 p.

Research output: Contribution to journalArticle (Academic Journal)

103 Citations (Scopus)
2007

Caveolin-1 and -2 and their relationship to cerebral amyloid angiopathy in Alzheimer's disease

van Helmond, Z., Miners, JS., Bednall, E., Chalmers, KA., Zhang, Y., Wilcock, GK., Love, S. & Kehoe, PG., Jun 2007, In : Neuropathology and Applied Neurobiology. 33 (3), p. 317 - 327 11 p.

Research output: Contribution to journalArticle (Academic Journal)

22 Citations (Scopus)

Cholinesterase inhibitors reduce cortical Aβ in dementia with Lewy bodies

Ballard, CG., Chalmers, KA., Todd, C., McKeith, IG., O`Brien, JT., Wilcock, GK., Love, S. & Perry, EK., May 2007, In : Neurology. 68 (20), p. 1726 - 1729 5 p.

Research output: Contribution to journalArticle (Academic Journal)

62 Citations (Scopus)

Neurofibrillary tangles may interfere with Smad 2/3 signaling in neurons

Chalmers, KA. & Love, S., Feb 2007, In : Journal of Neuropathology and Experimental Neurology. 66 (2), p. 158 - 167 10 p.

Research output: Contribution to journalArticle (Academic Journal)

46 Citations (Scopus)
14 Citations (Scopus)
2006

Caveolin-1 does not influence cerebrovascular accumulation of Abeta in Alzheimer`s disease

van Helmond, Z., Miners, JS., Chalmers, KA., Zhang, Y., Wilcock, GK., Love, S. & Kehoe, PG., 2006, Unknown. Vol. 2. p. S544

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Decreased Expression and Activity of Neprilysin in Alzheimer Disease Are Associated With Cerebral Amyloid Angiopathy

Miners, JS., van Helmond, Z., Chalmers, KA., Wilcock, GK., Love, S. & Kehoe, PG., Oct 2006, In : Journal of Neuropathology and Experimental Neurology. 65 (10), p. 1012 - 1021 10 p.

Research output: Contribution to journalArticle (Academic Journal)

109 Citations (Scopus)

Neurofibrillary tangles interfere with the transduction of TGF-beta signaling in neurons

Chalmers, KA., Wilcock, GK. & Love, S., 2006, International Congress of Neuropathology, San Francisco. Vol. 66. p. S159

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Reduced neprilysin expression in Alzheimer's disease is associated with APOE E4 and cerebral amyloid angiopathy

Miners, JS., van Helmond, Z., Chalmers, KA., Wilcock, GK., Love, S. & Kehoe, PG., Sep 2006, In : Brain Pathology. 16 (S1), p. S119 - S119 1 p.

Research output: Contribution to journalArticle (Academic Journal)

2005

Contributors to white matter damage in the frontal lobe in Alzheimer's disease

Chalmers, KA., Wilcock, GK. & Love, S., Dec 2005, In : Neuropathology and Applied Neurobiology. 31 (6), p. 623 - 631 9 p.

Research output: Contribution to journalArticle (Academic Journal)

37 Citations (Scopus)

Relationship of neurofibrillary pathology to cerebral amyloid angiopathy in Alzheimer's disease

Williams, S., Chalmers, KA., Wilcock, GK. & Love, S., Aug 2005, In : Neuropathology and Applied Neurobiology. 31 (4), p. 414 - 421 8 p.

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)

Sequence variants of IDE are associated with the extent of β-amyloid deposition in the Alzheimer's disease brain

Blomqvist, M., Chalmers, KA., Andreason, N., Bogdanovic, N., Wilcock, GK., Cairns, NJ., Feuk, L., Brookes, AJ., Love, S., Blennow, K., Kehoe, PG. & Prince, JA., Jun 2005, In : Neurobiology of Aging. 26 (6), p. 795 - 802 8 p.

Research output: Contribution to journalArticle (Academic Journal)

43 Citations (Scopus)
2004

APOE promoter, ACE1 and CYP46 polymorphisms and β-amyloid in Alzheimer's disease

Chalmers, KA., Culpan, D., Kehoe, PG., Wilcock, GK., Hughes, A. & Love, S., Jan 2004, In : NeuroReport. 15 (1), p. 95 - 98 4 p.

Research output: Contribution to journalArticle (Academic Journal)

38 Citations (Scopus)

Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism

Katzov, H., Chalmers, KA., Palmgren, J., Andreasen, N., Johansson, B., Cairns, NJ., Gatz, M., Wilcock, GK., Love, S., Pedersen, NL., Brookes, AJ., Blennow, K., Kehoe, PG. & Prince, JA., Apr 2004, In : Human Mutation. 23(4), p. 358 - 367 10 p.

Research output: Contribution to journalArticle (Academic Journal)

112 Citations (Scopus)
2003
127 Citations (Scopus)