Personal profile
Research interests
I am involved in a range of research aimed at better understanding how body mass index (BMI) exerts an effect on human health and disease. The main focus of my research is to evaluate the impact of BMI change on the metabolome. This includes the analysis of both nuclear magnetic resonance (NMR) and mass spectrometry (MS) derived metabolite data from randomised control trials (RCT) designed to evaluate the efficacy of both weight management programmes and bariatric surgery in achieving weight loss.
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Collaborations and top research areas from the last five years
Research output
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Cross-species studies implicate the melanocortin 3 receptor more strongly in the control of pubertal development than energy balance
Duckett, K., McClella, A., Corbin, L. J., Cimino, I., Elhakeem, A., Goncalves Soares, A. L., Williamson, A., Cross, E., Fairhurst-Hunter, Z., Petrovski, S., Rimmington, D., Alegre-Diaz, J., Berumen, J., Kuri-Morales, P., Tapia-Conyer, R., BELIEVE Study, Mokrosinski, J., Farooqi, I. S., Rasheed, A. & Saleheen, D. & 6 others, , 1 Jan 2026, In: Molecular Metabolism. 103, 65 p., 102301.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Quantitative biomarker profiling of serum samples in the By-Band-Sleeve trial
Smith, M. L., Goudswaard, L. J., Hughes, D. A., Blazeby, J., Rogers, C. A., Ring, S. M., Timpson, N. J. & Corbin, L. J., 7 Apr 2026, (E-pub ahead of print) In: Wellcome Open Research. 11, 12 p., 205.Research output: Contribution to journal › Article (Academic Journal)
Open Access -
Adiposity, metabolites and endometrial cancer risk: Inference from combinations of Mendelian randomization and Observational analyses
Tan, Y., Lee, M., Pournaras, D., Wang, S., Gunter, M., Dossus, L., Wade, K. H., Corbin, L. J. & Timpson, N. J., 21 Oct 2025, In: BMC Cancer. 25, 1, 15 p., 1619.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus)
Projects
- 2 Active
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Deep Molecular Phenotyping of the Impact of GLP-1 Therapy.
Timpson, N. J. (Co-Investigator), Corbin, L. J. (Co-Investigator) & Goudswaard, L. J. (Co-Investigator)
1/12/25 → 1/11/28
Project: Research
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Decoding Obesity: Exploring Proteomic and Metabolic Signatures of Obesity Subtypes Based on Body Composition Measures.
Timpson, N. J. (Principal Investigator), Corbin, L. J. (Co-Investigator) & Goudswaard, L. J. (Co-Investigator)
1/04/25 → 1/03/28
Project: Research
Datasets
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Genome-wide association study of cardiovascular outcomes in UK Biobank
Corbin, L. (Creator), Haycock, P. (Contributor) & Timpson, N. (Data Manager), University of Bristol, 6 Sept 2024
DOI: 10.5523/bris.h0p2qyebjcoa2ws47mmx3oohr, http://data.bris.ac.uk/data/dataset/h0p2qyebjcoa2ws47mmx3oohr
Dataset
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Epigenetic regulation of F2RL3 in vitro in response to exposure to cigarette smoke extract
Corbin, L. (Creator), Williams, C. M. (Creator), White, S. J. (Creator), Taylor, A. (Creator), Taylor, K. (Creator), Poole, A. (Contributor), Timpson, N. (Contributor) & Mumford, A. (Contributor), University of Bristol, 23 Dec 2021
DOI: 10.5523/bris.35olm77woaku72652wg0g0j6nf, http://data.bris.ac.uk/data/dataset/35olm77woaku72652wg0g0j6nf
Dataset
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Metabolite summary statistics for Mendelian randomization analyses
Langenberg, C. (Creator), Stewart, I. (Creator), Butterworth, A. (Creator), Surendran, P. (Creator), Tan, V. (Creator), Corbin, L. (Creator) & Timpson, N. (Creator), University of Bristol, 9 Sept 2021
DOI: 10.5523/bris.33bq35s9lbos026r1xukxijoqu, http://data.bris.ac.uk/data/dataset/33bq35s9lbos026r1xukxijoqu and one more link, https://data.bris.ac.uk/data/dataset/33bq35s9lbos026r1xukxijoqu (show fewer)
Dataset
Prizes
Activities
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Media press release 'Type 2 diabetes remission diet impacts on metabolic health'
Corbin, L. J. (Speaker)
26 Oct 2023Activity: Other activity types › Media coverage or participation
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Diabetologia (Journal)
Corbin, L. J. (Editor)
1 Jan 2023 → …Activity: Publication peer-review and editorial work types › Editorial activity
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BMJ Open Science (Journal)
Corbin, L. J. (Editor)
1 Sept 2017 → 1 Jan 2023Activity: Publication peer-review and editorial work types › Editorial activity