Dr Laurence J M S Howe

PhD, MSc, BSc

  • Oakfield/Barley House


Research output per year

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Research Output

  • 11 Article (Academic Journal)
  • 1 Review article (Academic Journal)

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

Brumpton, B., Sanderson, E., Heilbron, K., Hartwig, F. P., Harrison, S., Vie, G. Å., Cho, Y., Howe, L. D., Hughes, A., Boomsma, D. I., Havdahl, A., Hopper, J. L., Neale, M., Nivard, M. G., Pedersen, N. L., Reynolds, C., Tucker-Drob, E. M., Howe, L., Morris, T., Lin, S. & 14 others, The Within-family Consortium, the 23 and Me Research Team, Auton, A., Windmeijer, F., Chen, W-M., Bjørngaard, J. H., Hveem, K., Willer, C. J., Evans, D. M., Kaprio, J. A., Davey Smith, G., Åsvold, B. O., Hemani, G. & Davies, N. M., 14 Jul 2020, In : Nature Communications. 11, 13 p., 3519 (2020) .

Research output: Contribution to journalArticle (Academic Journal)

Open Access
  • 7 Downloads (Pure)

    Cleft lip/palate and educational attainment: cause, consequence, or correlation? A Mendelian randomization study

    Dardani, C., Howe, L. J. M. S., Mukhopadhyay, N., Stergiakouli, E., Wren, Y. E., Humphries, K. J., Davies, A. J. V., Ho, K. M., Weinberg, S., Marazita, M., Mangold, E., Ludwig, K., Relton, C. L., Davey Smith, G., Lewis, S. J., Sandy, J. R., Davies, N. M. & Sharp, G. C., 6 May 2020, In : International Journal of Epidemiology. 12 p., dyaa047.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
  • Evidence for DNA methylation mediating genetic liability to non-syndromic cleft lip/palate

    Howe, L., Richardson, T., Arathimos, R., Alvizi, L., Passos-Bueno, M. R., Stanier, P., Nohr, E. A., Ludwig, K., Mangold, E., Knapp, M., Stergiakouli, E., St Pourcain, B., Davey Smith, G., Sandy, J., Relton, C., Lewis, S., Hemani, G. & Sharp, G., 1 Feb 2019, In : Epigenomics. 11, 2, p. 133-145 13 p.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
  • 5 Citations (Scopus)
    163 Downloads (Pure)


    Supervised Work

    Exploring the aetiology and phenotypic consequences of non-syndromic cleft lip/palate using polygenic risk scoring and Mendelian randomization

    Author: Howe, L., 25 Sep 2018

    Supervisor: Davey Smith, G. (Supervisor), Lewis, S. (Supervisor) & St Pourcain, B. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)