20082020

Research output per year

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Research Output

  • 101 Article (Academic Journal)
  • 4 Letter (Academic Journal)
  • 2 Review article (Academic Journal)
  • 1 Comment/debate (Academic Journal)
Article (Academic Journal)

Adult height variants affect birth length and growth rate in children

Paternoster, L., Howe, LD., Tilling, K., Weedon, MN., Freathy, RM., Frayling, TM., Kemp, JP., Davey Smith, G., Timpson, NJ., Ring, SM., Evans, DM. & Lawlor, D., Jul 2011, In : Human Molecular Genetics. 20(20), p. 4069 - 4075 7 p.

Research output: Contribution to journalArticle (Academic Journal)

32 Citations (Scopus)

A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis

Esparza-Gordillo, J., Schaarschmidt, H., Liang, L., Cookson, W., Bauerfeind, A., Lee-Kirsch, M-A., Nemat, K., Henderson, J., Paternoster, L., Harper, J. I., Mangold, E., Nothen, M. M., Rüschendorf, F., Kerscher, T., Marenholz, I., Matanovic, A., Lau, S., Keil, T., Bauer, C-P., Kurek, M. & 9 others, Ciechanowicz, A., Macek, M., Franke, A., Kabesch, M., Hubner, N., Abecasis, G., Weidinger, S., Moffatt, M. & Lee, Y-A., Aug 2013, In : Journal of Allergy and Clinical Immunology. 132, 2, p. 371-7 7 p.

Research output: Contribution to journalArticle (Academic Journal)

49 Citations (Scopus)

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

Bønnelykke, K., Sleiman, P., Nielsen, K., Kreiner-Møller, E., Mercader, J. M., Belgrave, D., den Dekker, H. T., Husby, A., Sevelsted, A., Faura-Tellez, G., Mortensen, L. J., Paternoster, L., Flaaten, R., Mølgaard, A., Smart, D. E., Thomsen, P. F., Rasmussen, M. A., Bonàs-Guarch, S., Holst, C., Nohr, E. A. & 16 others, Yadav, R., March, M. E., Blicher, T., Lackie, P. M., Jaddoe, V. W. V., Simpson, A., Holloway, J. W., Duijts, L., Custovic, A., Davies, D. E., Torrents, D., Gupta, R., Hollegaard, M. V., Hougaard, D. M., Hakonarson, H. & Bisgaard, H., Jan 2014, In : Nature Genetics. 46, 1, p. 51–55 5 p.

Research output: Contribution to journalArticle (Academic Journal)

278 Citations (Scopus)

A genome-wide association study of body mass index across early life and childhood

Warrington, N. M., Howe, L. D., Paternoster, L., Kaakinen, M., Herrala, S., Huikari, V., Wu, Y. Y., Kemp, J. P., Timpson, N. J., Pourcain, B. S., Davey Smith, G., Tilling, K., Jarvelin, M-R., Pennell, C. E., Evans, D. M., Lawlor, D. A., Briollais, L. & Palmer, L. J., 7 May 2015, In : International Journal of Epidemiology. 44, 2, p. 700-712 12 p.

Research output: Contribution to journalArticle (Academic Journal)

61 Citations (Scopus)

Age-of-onset information helps identify 76 genetic variants associated with allergic disease

Ferreira, M. A. R., Granell, R., Brumpton, B. M., Paternoster, L. & al., E., 20 Mar 2020, (Accepted/In press) In : PLoS Genetics.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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38 Citations (Scopus)
282 Downloads (Pure)

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

Ried, J. S., Jeff, J., Chu, A., et, A., McArdle, W., Paternoster, L., Sorensen, T. & Loos, R. J. F., 23 Nov 2016, In : Nature Communications. 7, 11 p., 13357.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
28 Citations (Scopus)
174 Downloads (Pure)

A rare mutation in SMAD9 associated with high bone mass identifies the SMAD-dependent BMP signalling pathway as a potential anabolic target for osteoporosis

Brown, M. A., Hammond, C., Kemp, J. P., Duncan, E. L. & AOGC Consortium, 16 Sep 2019, In : Journal of Bone and Mineral Research. 40 p.

Research output: Contribution to journalArticle (Academic Journal)

Assessment of a causal relationship between body mass index and atopic dermatitis

Budu-Aggrey, A., Watkins, S. H., Brumpton, B. M., Løset, M., Tyrrell, J., Modalsli, E. H., Vie, G. Å., Palmer, T., Fritsche, L. G., Nielsen, J. B., Romundstad, P. R., Davey Smith, G., Åsvold, B. O., Paternoster, L. & Brown, S. J., 17 Apr 2020, In : Journal of Allergy and Clinical Immunology. 3 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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9 Downloads (Pure)

Association between apolipoprotein E genotype and carotid intima-media thickness may suggest a specific effect on large artery atherothrombotic stroke

Paternoster, L., Martínez González, NA., Lewis, S. & Sudlow, CL., Jan 2008, In : Stroke. 39, p. 48 - 54 7 p.

Research output: Contribution to journalArticle (Academic Journal)

45 Citations (Scopus)

Association between CST3 rs2424577 Polymorphism and Corpulence Related Phenotypes during Lifetime in Populations of European Ancestry

Hooton, H., Dubern, B., Henegar, C., Paternoster, L., Nohr, EA., Alili, R., Rousseau, F., Pelloux, V., Galan, P., Hercberg, S., Arner, P., Sørensen, TI. & Clément, K., 2011, In : Obesity Facts. p. 131 - 144

Research output: Contribution to journalArticle (Academic Journal)

5 Citations (Scopus)

Association between Maternal Fish Consumption and Gestational Weight Gain: Influence of Molecular Genetic Predisposition to Obesity

Larsen, S. C., Ängquist, L., Laurin, C., Morgen, C. S., Jakobsen, M. U., Paternoster, L., Smith, G. D., Olsen, S. F., Sorensen, T. & Nohr, E. A., 1 Mar 2016, In : PLoS ONE. 11, 3, 16 p., e0150105.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
237 Downloads (Pure)

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study

Haycock, P. C., Burgess, S., Nounu, A., Zheng, J., Okoli, G. N., Bowden, J., Wade, K. H., Timpson, N. J., Evans, D. M., Willeit, P., Aviv, A., Gaunt, T. R., Hemani, G., Mangino, M., Ellis, H. P., Kurian, K. M., Pooley, K. A., Eeles, R. A., Lee, J. E., Fang, S. & 31 others, Chen, W. V., Law, M. H., Bowdler, L. M., Iles, M. M., Yang, Q., Worrall, B. B., Markus, H. S., Hung, R. J., Amos, C. I., Spurdle, A. B., Thompson, D. J., O'Mara, T. A., Wolpin, B., Amundadottir, L., Stolzenberg-Solomon, R., Trichopoulou, A., Onland-Moret, N. C., Lund, E., Duell, E. J., Canzian, F., Severi, G., Overvad, K., Gunter, M. J., Tumino, R., Brennan, P., Paternoster, L., Soranzo, N., Relton, C. L., Martin, R. M., Davey Smith, G. & Telomeres Mendelian Randomization Collaboration, May 2017, In : JAMA Oncology. 3, 5, p. 636-651 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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146 Citations (Scopus)
190 Downloads (Pure)

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

Skaaby, T., Kilpeläinen, T. O., Taylor, A. E., Mahendran, Y., Wong, A., Ahluwalia, T. S., Paternoster, L., Trompet, S., Stott, D. J., Flexeder, C., Zhou, A., Brusselle, G., Sajjad, A., Lahousse, L., Tiemeier, H., Have, C. T., Thuesen, B. H., Kårhus, L. L., Møllehave, L. T., Leth-Møller, K. B. & 27 others, Shabanzadeh, D. M., Gonzalez-Quintela, A., Power, C., Hyppönen, E., Kuh, D., Hardy, R., Meitinger, T., Jukema, J. W., Völker, U., Nauck, M., Völzke, H., Friedrich, N., Bonten, T. N., Noordam, R., Mook-Kanamori, D. O., Tolstrup, J. S., Taube, C., Peters, A., Grallert, H., Strauch, K., Schulz, H., Grarup, N., Hansen, T., Pedersen, O., Burgess, S., Munafò, M. R. & Linneberg, A., Feb 2019, In : Addiction. 114, 2, p. 216-225 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
134 Downloads (Pure)

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

Vimaleswaran, K. S., Cavadino, A., Berry, D. J., Jorde, R., Dieffenbach, A. K., Lu, C., Alves, A. C., Heerspink, H. J. L., Tikkanen, E., Eriksson, J., Wong, A., Mangino, M., Jablonski, K. A., Nolte, I. M., Houston, D. K., Ahluwalia, T. S., van der Most, P. J., Pasko, D., Zgaga, L., Thiering, E. & 31 others, Vitart, V., Fraser, R. M., Huffman, J. E., de Boer, R. A., Schöttker, B., Saum, K-U., McCarthy, M. I., Dupuis, J., Herzig, K-H., Sebert, S., Pouta, A., Laitinen, J., Kleber, M. E., Navis, G., Lorentzon, M., Jameson, K., Arden, N., Cooper, J. A., Acharya, J., Hardy, R., Raitakari, O., Ripatti, S., Billings, L. K., Lahti, J., Paternoster, L., Wright, A. F., Wilson, J. F., Sorensen, T., Kumari, M., Kivimaki, M. & LifeLines Cohort Study investigators, Sep 2014, In : Lancet Diabetes and Endocrinology. 2, 9, p. 719-729

Research output: Contribution to journalArticle (Academic Journal)

204 Citations (Scopus)

Associations of genetic determinants of vitamin B12 and folate status with hay fever and asthma: a Mendelian randomization meta-analysis

Skaaby, T., Taylor, A. E., Jacobsen, R. K., Møllehave, L. T., Friedrich, N., Thuesen, B. H., Shabanzadeh, D. M., Paternoster, L., Völker, U., Nauck, M., Völzke, H., Munafò, M., Hansen, T., Pedersen, O., Jørgensen, T., Grarup, N. & Linneberg, A., 18 Dec 2017, In : European Journal of Clinical Nutrition. 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
284 Downloads (Pure)

Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

Waage, J., Standl, M., Jessen, L. E., Thorsen, J., Tian, C., Schoettler, N., the 23 and Me Research Team, Flores, C., Abdellaoui, A., Ahluwalia, T. S., Alves, A. C., Amaral, A. F. S., Antó, J. M., Arnold, A., Barreto-Luis, A., Baurecht, H., van Beijsterveldt, C. E. M., Bleecker, E. R., Bonàs-Guarch, S., Boomsma, D. I. & 31 others, Brix, S., Bunyavanich, S., Burchard, E. G., Chen, Z., Curjuric, I., Custovic, A., den Dekker, H. T., Dharmage, S. C., Dmitrieva, J., Duijts, L., Ege, M. J., Gauderman, W. J., Georges, M., Gieger, C., Gilliland, F., Granell, R., Gui, H., Hansen, T., Heinrich, J., Hernandez-Pacheco, N., Holt, P., Imboden, M., Jaddoe, V. W. V., Jarvelin, M-R., Jarvis, D. L., Jensen, K. K., Jónsdóttir, I., Kabesch, M., Kaprio, J., Kumar, A. & Paternoster, L., Sep 2018, In : Nature Genetics. 50, 9, 1 p., 1343.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
1 Citation (Scopus)

Body Stature Growth Trajectories during Childhood and the Development of Myopia

Northstone, K., Guggenheim, J. A., Howe, L. D., Tilling, K., Paternoster, L., Kemp, J. P., McMahon, G. & Williams, C., May 2013, In : Ophthalmology. 120, 5, p. 1064-73.e1

Research output: Contribution to journalArticle (Academic Journal)

26 Citations (Scopus)

Clinical onset of atopic eczema: Results from 2 nationally representative British birth cohorts followed through midlife

Abuabara, K., Ye, M., McCulloch, C. E., Sullivan, A., Margolis, D. J., Strachan, D. P., Paternoster, L., Yew, Y. W., Williams, H. C. & Langan, S. M., 1 Sep 2019, In : Journal of Allergy and Clinical Immunology. 144, 3, p. 710-719 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
7 Citations (Scopus)
90 Downloads (Pure)

Cohort Profile: Nausea and vomiting during pregnancy genetics consortium (NVP Genetics Consortium)

Colodro-Conde, L., Cross, S. M., Lind, P. A., Painter, J. N., Gunst, A., Jern, P., Johansson, A., Maegbaek, M. L., Munk-Olsen, T., Nyholt, D. R., Ordoñana, J. R., Paternoster, L., Sánchez-Romera, J. F., Wright, M. J. & Medland, S. E., Apr 2017, In : International Journal of Epidemiology. 46, 2, 8 p., e17.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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8 Citations (Scopus)
243 Downloads (Pure)

Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study

Hollensted, M., Ahluwalia, T. S., Have, C. T., Grarup, N., Fonvig, C. E., Nielsen, T. R. H., Trier, C., Paternoster, L., Pedersen, O., Holm, J-C., Sorensen, T. & Hansen, T., 11 Nov 2015, In : BMC Medical Genetics. 16, 9 p., 105.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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7 Citations (Scopus)
221 Downloads (Pure)

Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5

Hunt, L. E., Noyvert, B., Bhaw-Rosun, L., Sesay, A. K., Paternoster, L., Nohr, E. A., Davey Smith, G., Tommerup, N., Sorensen, T. & Elgar, G., 7 Dec 2015, In : Genome Medicine. 7, 14 p., 126.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
8 Citations (Scopus)
271 Downloads (Pure)
Open Access
File
3 Citations (Scopus)
132 Downloads (Pure)

Differential associations of allergic disease genetic variants with developmental profiles of eczema, wheeze and rhinitis

Clark, H., Granell, R., Curtin, J. A., Belgrave, D. C. M., Simpson, A., Murray, C., Henderson, A. J., Custovic, A. & Paternoster, L., 23 Aug 2019, In : Clinical and Experimental Allergy. 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
168 Downloads (Pure)

Does bone resorption stimulate periosteal expansion ? A cross sectional analysis of Beta-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT

Kemp, J. P., Sayers, A., Paternoster, L., Evans, D. M., Deere, K., St Pourcain, B., Timpson, N. J., Ring, S. M., Lorentzon, M., Lehtimaki, T., Eriksson, J., Kahonen, M., Raitakari, O., Laaksonen, M., Sievanen, H., Viikari, J., Lyytikainen, L-P., Smith, G. D., Fraser, W. D., Vandenput, L. & 2 others, Ohlsson, C. & Tobias, J. H., Apr 2014, In : Journal of Bone and Mineral Research. 29, 4, p. 1015-1024 10 p.

Research output: Contribution to journalArticle (Academic Journal)

16 Citations (Scopus)

Eleven loci with new reproducible genetic associations with allergic disease risk

the 23 and Me Research Team & the collaborators of the SHARE study, 19 Apr 2018, In : Journal of Allergy and Clinical Immunology. 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
16 Citations (Scopus)
234 Downloads (Pure)

EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis

Elias, M. S., Wright, S. C., Remenyi, J., Abbott, J. C., Bray, S. E., Cole, C., Edwards, S., Gierlinski, M., Glok, M., McGrath, J. A., Nicholson, W. V., Paternoster, L., Prescott, A. R., Have, S. T., Whitfield, P. D., Lamond, A. I. & Brown, S. J., 1 Aug 2019, In : Journal of Allergy and Clinical Immunology. 144, 2, p. 470-481 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
128 Downloads (Pure)

Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization

Skaaby, T., Taylor, A. E., Thuesen, B. H., Jacobsen, R. K., Friedrich, N., Møllehave, L. T., Hansen, S., Larsen, S. C., Völker, U., Nauck, M., Völzke, H., Hansen, T., Pedersen, O., Jørgensen, T., Paternoster, L., Munafò, M., Grarup, N. & Linneberg, A., 1 Jan 2018, In : Allergy. 73, 1, p. 153-164 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
16 Citations (Scopus)
306 Downloads (Pure)

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study

Budu-Aggrey, A., Brumpton, B., Tyrrell, J., Watkins, S., Modalsli, E. H., Celis-Morales, C., Ferguson, L. D., Vie, G. Å., Palmer, T., Fritsche, L. G., Løset, M., Nielsen, J. B., Zhou, W., Tsoi, L. C., Wood, A. R., Jones, S. E., Beaumont, R., Saunes, M., Romundstad, P. R., Siebert, S. & 8 others, McInnes, I. B., Elder, J. T., Davey Smith, G., Frayling, T. M., Åsvold, B. O., Brown, S. J., Sattar, N. & Paternoster, L., 31 Jan 2019, In : PLoS Medicine. 19, 1, p. 71-86 18 p., e1002739.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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25 Citations (Scopus)
211 Downloads (Pure)

Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants

van der Valk, R. J. P., Duijts, L., Timpson, N. J., Salam, M. T., Standl, M., Curtin, J. A., Genuneit, J., Kerhof, M., Kreiner-Møller, E., Cáceres, A., Gref, A., Liang, L. L., Taal, H. R., Bouzigon, E., Demenais, F., Nadif, R., Ober, C., Thompson, E. E., Estrada, K., Hofman, A. & 31 others, Uitterlinden, A. G., van Duijn, C., Rivadeneira, F., Li, X., Eckel, S. P., Berhane, K., Gauderman, W. J., Granell, R., Evans, D. M., St Pourcain, B., McArdle, W., Kemp, J. P., Smith, G. D., Tiesler, C. M. T., Flexeder, C., Simpson, A., Murray, C. S., Fuchs, O., Postma, D. S., Bønnelykke, K., Torrent, M., Andersson, M., Sleiman, P., Hakonarson, H., Cookson, W. O., Moffatt, M. F., Paternoster, L., Melén, E., Sunyer, J., Bisgaard, H. & for the EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium, 5 Dec 2013, In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle (Academic Journal)

25 Citations (Scopus)

Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits

Dashti, H. S., Follis, J. L., Smith, C. E., Tanaka, T., Garaulet, M., Gottlieb, D. J., Hruby, A., Jacques, P. F., Kiefte-de Jong, J. C., Lamon-Fava, S., Scheer, F. A. J. L., Bartz, T. M., Kovanen, L., Wojczynski, M. K., Frazier-Wood, A. C., Ahluwalia, T. S., Perälä, M-M., Jonsson, A., Muka, T., Kalafati, I. P. & 3 others, Mikkilä, V., Ordovás, J. M. & CHARGE Nutrition Study Group, Aug 2015, In : Diabetes Care. 38, 8, p. 1456-1466 11 p.

Research output: Contribution to journalArticle (Academic Journal)

23 Citations (Scopus)

Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct

the 23 and Me Research Team, eQTLGen Consortium & BIOS Consortium, 4 Apr 2019, In : American Journal of Human Genetics. 104, 4, p. 665-684 20 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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14 Citations (Scopus)
158 Downloads (Pure)

Genetic associations with brain microbleeds: systematic review and meta-analyses

Maxwell, SS., Jackson, CA., Paternoster, L., Cordonnier, C., Thijs, V., Al-Shahi Salman, R. & Sudlow, CL., 2011, In : Neurology. 77, p. 158 - 167

Research output: Contribution to journalArticle (Academic Journal)

Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure

Paternoster, L., Lorentzon, M., Lehtimäki, T., Eriksson, J., Kähönen, M., Raitakari, O., Laaksonen, M., Sievänen, H., Viikari, J., Lyytikäinen, L-P., Mellström, D., Karlsson, M., Ljunggren, O., Grundberg, E., Kemp, J. P., Sayers, A., Nethander, M., Evans, D. M., Vandenput, L., Tobias, J. H. & 1 others, Ohlsson, C., 2013, In : PLoS Genetics. 9, 2, p. e1003247

Research output: Contribution to journalArticle (Academic Journal)

65 Citations (Scopus)
63 Citations (Scopus)

Genetic effects on carotid intima-media thickness: systematic assessment and meta-analyses of candidate gene polymorphisms studied in more than 5000 subjects

Paternoster, L., Martinez-Gonzalez, NA., Charleton, R., Chung, M., Lewis, S. & Sudlow, CL., Feb 2010, In : Circulation: Cardiovascular Genetics. 3, p. 15 - 21

Research output: Contribution to journalArticle (Academic Journal)

36 Citations (Scopus)

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

Tyrrell, J., Richmond, R. C., Palmer, T. M., Feenstra, B., Rangarajan, J., Metrusky, S., Cavadino, A., Paternoster, L., Armstrong, L. L., De Silva, N. M. G., Wood, A. R., Horikoshi, M., Geller, F., Myhre, R., Bradfield, J. P., Kreiner-Møller, E., Huikari, V., Painter, J. N., Hottenga, J. J., Allard, C. & 44 others, Berry, D. J., Bouchard, L., Das, S., Evans, D. M., Hakonarson, H., Hayes, M. G., Heikkinen, J., Hofman, A., Knight, B. A., Lind, P. A., McCarthy, M. I., McMahon, G., Medland, S. E., Melbye, M., Morris, A. P., Nodzenski, M., Reichetzeder, C., Ring, S. M., Sebed, S., Sengpiel, V., Sorensen, T. I. A., Willemsen, G., de Geus, E. J. C., Martin, N. G., Spector, T. D., Power, C., Järvelin, M-R., Bisgaard, H., Grant, S. F. A., Nohr, E. A., Jaddoe, VW., Jacobsson, B., Murray, J. C., Hocher, B., Hattersley, A. T., Scholtens, D. M., Davey Smith, G., Hivert, M-F., Felix, J. F., Hyppönen, E., Lowe, W. L., Frayling, T. M., Lawlor, D. A. & Freathy, R. M., 15 Mar 2016, In : JAMA - Journal of the American Medical Association. 315, 11, p. 1129-1140 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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103 Citations (Scopus)
337 Downloads (Pure)

Genetic Influences on Trajectories of Systolic Blood Pressure Across Childhood and Adolescence

Howe, L. D., Parmar, P. G., Paternoster, L., Warrington, N. M., Kemp, J. P., Briollais, L., Newnham, J. P., Timpson, N. J., Smith, G. D., Ring, S. M., Evans, D. M., Tilling, K., Pennell, C. E., Beilin, L. J., Palmer, L. J. & Lawlor, D. A., Dec 2013, In : Circulation: Cardiovascular Genetics. 6, 6, p. 608-614 7 p.

Research output: Contribution to journalArticle (Academic Journal)

14 Citations (Scopus)

Genetic Relationship between Schizophrenia and Nicotine Dependence

Cotinine meta-analysis group, FTND meta-analysis group , Stiby, A., Hemani, G., Paternoster, L., Timpson, N., Davey Smith, G. & Taylor, M., 10 May 2016, In : Scientific Reports. 6, 10 p., 25671.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
30 Citations (Scopus)
236 Downloads (Pure)

Genetics of depressive symptoms in adolescence

Sallis, H., Evans, J., Wootton, R., Krapohl, E., Oldehinkel, A. J., Davey Smith, G. & Paternoster, L., 31 Aug 2017, In : BMC Psychiatry. 17, 8 p., 321.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
230 Downloads (Pure)

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Okbay, A., Baselmans, B. M. L., De Neve, J-E., Turley, P., Nivard, M. G., Fontana, M. A., Meddens, S. F. W., Linnér, R. K., Rietveld, C. A., Derringer, J., Gratten, J., Lee, J. J., Liu, J. Z., de Vlaming, R., Ahluwalia, T. S., Buchwald, J., Cavadino, A., Frazier-Wood, A. C., Furlotte, N. A., Garfield, V. & 31 others, Geisel, M. H., Gonzalez, J. R., Haitjema, S., Karlsson, R., van der Laan, S. W., Ladwig, K-H., Lahti, J., van der Lee, S. J., Lind, P. A., Liu, T., Matteson, L., Mihailov, E., Miller, M. B., Minica, C. C., Nolte, I. M., Mook-Kanamori, D., van der Most, P. J., Oldmeadow, C., Qian, Y., Raitakari, O., Rawal, R., Stergiakouli, E., Davis, O. S. P., Fatemifar, G., Paternoster, L., Haworth, C. M. A., Sorensen, T., Timpson, N. J., Smith, G. D., Medland, S. E. & LifeLines Cohort Study, Jun 2016, In : Nature Genetics. 48, 6, p. 624-633 13 p.

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Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index

Freathy, R. M., Kazeem, G. R., Morris, R. W., Johnson, P. C. D., Paternoster, L., Ebrahim, S., Hattersley, A. T., Hill, A., Hingorani, A. D., Holst, C., Jefferis, B. J., Kring, S. I. I., Mooser, V., Padmanabhan, S., Preisig, M., Ring, S. M., Sattar, N., Upton, M. N., Vollenweider, P., Waeber, G. & 8 others, Sorensen, T., Frayling, T. M., Watt, G., Lawlor, D. A., Whincup, P. H., Tozzi, F., Davey Smith, G. & Munafò, M., Dec 2011, In : International Journal of Epidemiology. 40, 6, p. 1617 - 1628 12 p.

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Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight

Tyrrell, J., Huikari, V., Christie, J. T., Cavadino, A., Bakker, R., Brion, M-J. A., Geller, F., Paternoster, L., Myhre, R., Potter, C., Johnson, P. C. D., Ebrahim, S., Feenstra, B., Hartikainen, A-L., Hattersley, A. T., Hofman, A., Kaakinen, M., Lowe, L. P., Magnus, P., McConnachie, A. & 24 others, Melbye, M., Ng, J. W. Y., Nohr, E. A., Power, C., Ring, S. M., Sebert, S. P., Sengpiel, V., Taal, H. R., Watt, G. C. M., Sattar, N., Relton, C. L., Jacobsson, B., Frayling, T. M., Sorensen, T., Murray, J. C., Lawlor, D. A., Pennell, C. E., Jaddoe, V. W. V., Hypponen, E., Lowe, W. L., Jarvelin, M-R., Smith, G. D., Freathy, R. M. & Early Growth Genetics EGG, 15 Dec 2012, In : Human Molecular Genetics. 21, 24, p. 5344-5358 15 p.

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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Ligthart, S., LifeLines Cohort Study, CHARGE Inflammation Working Group, Vaez, A., Võsa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., Van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Wu, Y., Karlsson, R., Barbalic, M., Lin, H., Pool, R., Zhu, G., Macé, A., Sidore, C. & 32 others, Trompet, S., Mangino, M., Sabater-Lleal, M., Kemp, J. P., Abbasi, A., Kacprowski, T., Verweij, N., Smith, A. V., Huang, T., Marzi, C., Feitosa, M. F., Lohman, K. K., Kleber, M. E., Milaneschi, Y., Mueller, C., Huq, M., Vlachopoulou, E., Lyytikäinen, L. P., Oldmeadow, C., Deelen, J., Perola, M., Zhao, J., Davey-Smith, G., Hicks, A., Timpson, N., St. Pourcain, B., Soranzo, N., Paternoster, L., Evans, D. M., Hicks, A., Palmer, L. J. & Davey-Smith, G., 1 Nov 2018, In : American Journal of Human Genetics. 103, 5, p. 691-706 16 p.

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Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci

the 23 and Me Research Team, Dudding, T., Haworth, S., Lind, P. A., Sathirapongsasuti, J. F., Agee, M., Alipanahi, B., Auton, A., Bell, R. K., Bryc, K., Elson, S. L., Fontanillas, P., Furlotte, N. A., Hicks, B., Hinds, D. A., Huber, K. E., Jewett, E. M., Jiang, Y., Kleinman, A., Lin, K. H. & 26 others, Litterman, N. K., McCeight, J. C., McIntyre, M. H., McManus, K. F., Mountain, J. L., Noblin, E. S., Northover, C. A. M., Pitts, S. J., Poznik, G. D., Shelton, J. F., Shringarpure, S., Tian, C., Vacic, V., Wang, X., Wilson, C. H., Tung, J. Y., Mitchell, R., Colodro-Conde, L., Medland, S. E., Gordon, S., Elsworth, B., Paternoster, L., Franks, P. W., Thomas, S. J., Martin, N. G. & Timpson, N. J., 5 Mar 2019, In : Nature Communications. 10, 12 p., 1052.

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Genome-wide analysis identifies 12 loci influencing human reproductive behavior

Barban, N., Jansen, R., De Vlaming, R., Vaez, A., Mandemakers, J. J., Tropf, F. C., Shen, X., Wilson, J. F., Chasman, D. I., Nolte, I. M., Tragante, V., Van Der Laan, S. W., Perry, J. R. B., Kong, A., Ahluwalia, T. S., Albrecht, E., Yerges-Armstrong, L., Atzmon, G., Auro, K., Ayers, K. & 233 others, Bakshi, A., Ben-Avraham, D., Berger, K., Bergman, A., Bertram, L., Bielak, L. F., Bjornsdottir, G., Bonder, M. J., Broer, L., Bui, M., Barbieri, C., Cavadino, A., Chavarro, J. E., Turman, C., Concas, M. P., Cordell, H. J., Davies, G., Eibich, P., Eriksson, N., Esko, T., Eriksson, J., Falahi, F., Felix, J. F., Fontana, M. A., Franke, L., Gandin, I., Gaskins, A. J., Gieger, C., Gunderson, E. P., Guo, X., Hayward, C., He, C., Hofer, E., Huang, H., Joshi, P. K., Kanoni, S., Karlsson, R., Kiechl, S., Kifley, A., Kluttig, A., Kraft, P., Lagou, V., Lecoeur, C., Lahti, J., Li-Gao, R., Lind, P. A., Liu, T., Makalic, E., Mamasoula, C., Matteson, L., Mbarek, H., McArdle, P. F., McMahon, G., Meddens, S. F. W., Mihailov, E., Miller, M., Missmer, S. A., Monnereau, C., Van Der Most, P. J., Myhre, R., Nalls, M. A., Nutile, T., Kalafati, I. P., Porcu, E., Prokopenko, I., Rajan, K. B., Rich-Edwards, J., Rietveld, C. A., Robino, A., Rose, L. M., Rueedi, R., Ryan, K. A., Saba, Y., Schmidt, D., Smith, J. A., Stolk, L., Streeten, E., Tönjes, A., Thorleifsson, G., Ulivi, S., Wedenoja, J., Wellmann, J., Willeit, P., Yao, J., Yengo, L., Zhao, J. H., Zhao, W., Zhernakova, D. V., Amin, N., Andrews, H., Balkau, B., Barzilai, N., Bergmann, S., Biino, G., Bisgaard, H., Bønnelykke, K., Boomsma, D. I., Buring, J. E., Campbell, H., Cappellani, S., Ciullo, M., Cox, S. R., Cucca, F., Toniolo, D., Davey-Smith, G., Deary, I. J., Dedoussis, G., Deloukas, P., Van Duijn, C. M., De Geus, E. J. C., Eriksson, J. G., Evans, D. A., Faul, J. D., Sala, C. F., Froguel, P., Gasparini, P., Girotto, G., Grabe, H. J., Greiser, K. H., Groenen, P. J. F., De Haan, H. G., Haerting, J., Harris, T. B., Heath, A. C., Heikkilä, K., Hofman, A., Homuth, G., Holliday, E. G., Hopper, J., Hyppönen, E., Jacobsson, B., Jaddoe, V. W. V., Johannesson, M., Jugessur, A., Kähönen, M., Kajantie, E., Kardia, S. L. R., Keavney, B., Kolcic, I., Koponen, P., Kovacs, P., Kronenberg, F., Kutalik, Z., La Bianca, M., Lachance, G., Iacono, W. G., Lai, S., Lehtimäki, T., Liewald, D. C., Lindgren, C. M., Liu, Y., Luben, R., Lucht, M., Luoto, R., Magnus, P., Magnusson, P. K. E., Martin, N. G., McGue, M., McQuillan, R., Medland, S. E., Meisinger, C., Mellström, D., Metspalu, A., Traglia, M., Milani, L., Mitchell, P., Montgomery, G. W., Mook-Kanamori, D., De Mutsert, R., Nohr, E. A., Ohlsson, C., Olsen, J., Ong, K. K., Paternoster, L., Pattie, A., Penninx, B. W. J. H., Perola, M., Peyser, P. A., Pirastu, M., Polasek, O., Power, C., Kaprio, J., Raffel, L. J., Räikkönen, K., Raitakari, O., Ridker, P. M., Ring, S. M., Roll, K., Rudan, I., Ruggiero, D., Rujescu, D., Salomaa, V., Schlessinger, D., Schmidt, H., Schmidt, R., Schupf, N., Smit, J., Sorice, R., Spector, T. D., Starr, J. M., Stöckl, D., Strauch, K., Stumvoll, M., Swertz, M. A., Thorsteinsdottir, U., Thurik, A. R., Timpson, N. J., Tung, J. Y., Uitterlinden, A. G., Vaccargiu, S., Viikari, J., Vitart, V., Völzke, H., Vollenweider, P., Vuckovic, D., Waage, J., Wagner, G. G., Wang, J. J., Wareham, N. J., Weir, D. R., Willemsen, G., Willeit, J., Wright, A. F., Zondervan, K. T., Stefansson, K., Krueger, R. F., Lee, J. J., Benjamin, D. J., Cesarini, D., Koellinger, P. D., Den Hoed, M., Snieder, H. & Mills, M. C., Dec 2016, In : Nature Genetics. 48, 12, p. 1462-1472 11 p.

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Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

Waage, J., Standl, M., Curtin, J. A., Jessen, L. E., Thorsen, J., Tian, C., Schoettler, N., the 23 and Me Research Team & AAGC Collaborators, Aug 2018, In : Nature Genetics. 50, 8, p. 1072-1080 9 p.

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Genome-Wide Association Meta-Analysis of Cortical Bone Mineral Density Unravels Allelic Heterogeneity at the RANKL Locus and Potential Pleiotropic Effects on Bone

Paternoster, L., Lorentzon, M., Vandenput, L., Karlsson, MK., Ljunggren, O., Kindmark, A., Mellstrom, D., Kemp, J. P., Jarett, CE., Holly, JMP., Sayers, AE., St. Pourcain, M. U. B., Timpson, NJ., Deloukas, P., Davey Smith, G., Ring, SM., Evans, DM., Tobias, J. H. & Ohlsson, C., Nov 2010, In : PLoS Genetics. 6, 11, 12 p., e1001217.

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Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

Deelen, J., Beekman, M., Uh, H-W., Broer, L., Ayers, K. L., Tan, Q., Kamatani, Y., Bennet, A. M., Tamm, R., Trompet, S., Guðbjartsson, D. F., Flachsbart, F., Rose, G., Viktorin, A., Fischer, K., Nygaard, M., Cordell, H. J., Crocco, P., van den Akker, E. B., Böhringer, S. & 67 others, Helmer, Q., Nelson, C. P., Saunders, G. I., Alver, M., Andersen-Ranberg, K., Breen, M. E., van der Breggen, R., Caliebe, A., Capri, M., Cevenini, E., Collerton, J. C., Dato, S., Davies, K., Ford, I., Gampe, J., Garagnani, P., de Geus, E. J. C., Harrow, J., van Heemst, D., Heijmans, B. T., Heinsen, F-A., Hottenga, J-J., Hofman, A., Jeune, B., Jonsson, P. V., Lathrop, M., Lechner, D., Martin-Ruiz, C., McNerlan, S. E., Mihailov, E., Montesanto, A., Mooijaart, S. P., Murphy, A., Nohr, E. A., Paternoster, L., Postmus, I., Rivadeneira, F., Ross, O. A., Salvioli, S., Sattar, N., Schreiber, S., Stefánsson, H., Stott, D. J., Tiemeier, H., Uitterlinden, A. G., Westendorp, R. G. J., Willemsen, G., Samani, N. J., Galan, P., Sorensen, T., Boomsma, D. I., Jukema, J. W., Rea, I. M., Passarino, G., de Craen, A. J. M., Christensen, K., Nebel, A., Stefánsson, K., Metspalu, A., Magnusson, P., Blanché, H., Christiansen, L., Kirkwood, T. B. L., van Duijn, C. M., Franceschi, C., Houwing-Duistermaat, J. J. & Slagboom, P. E., 15 Aug 2014, In : Human Molecular Genetics. 23, 16, p. 4420–4432

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Genome-wide associations for birth weight and correlations with adult disease

Horikoshi, M., Beaumont, R., Day, F., Warrington, N., Kooijman, M., et. al., on behalf of the Early Growth Genetics (ECG) Consortium, Ring, S. M., Hemani, G., McMahon, G., Sorensen, T., Lawlor, D. A., Davey Smith, G., Timpson, N. J., Evans, D., Freathy, R. M. & Paternoster, L., 13 Oct 2016, In : Nature. 538, 7624, p. 248-252 5 p.

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