Projects per year
Personal profile
Research interests
In our lab we are interested in employing synthetic organic chemistry as a tool to probe and manipulate the structure and function of biologically relevant molecules to study biological problems and potentially discover treatments for diseases.
Carbohydrates have emerged as important factors of molecular recognition in biology and medicine. Understanding the roles of these complex molecules, which are found on the surface of cells as part of glycoproteins or glycolipids is of great importance. However, the synthesis of these oligosaccharide structures is still a challenging task.
Our current research interests focus on the development of new synthetic techniques for the facile synthesis of oligosaccharide libraries and glycoconjugates drug analogues.
We are also interested in the development of multivalent platforms to study carbohydrate-protein interactions in the context of disease.
Dr Galan is a supervisor in the EPSRC Centre for Doctoral Training in Chemical Synthesis
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Bio-Inspired Fluorescent Carbon Dots as probes for rapid detection of bacteria in physiological samples
1/10/19 → 30/09/23
Project: Research
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Bio-Inspired Fluorescent Carbon Dots as Probes for Rapid Detection of Bacteria inPhysiological Samples
1/10/19 → 30/09/23
Project: Research, Parent
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Research output
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Diphosphine Bioconjugates via Pt(0)-Catalyzed Hydrophosphination. A Versatile Chelator Platform for Technetium-99m and Rhenium-188 Radiolabeling of Biomolecules
Nuttall, R. E., Pham, T. T., Chadwick, A. C., Hungnes, I. N., Firth, G., Heckenast, M. A., Sparkes, H. A., Galan, M. C., Ma, M. T. & Pringle, P. G., 31 Jan 2023, (E-pub ahead of print) In: Inorganic Chemistry.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Editorial: Recent advances in carbohydrate chemical and enzymatic syntheses
Galan, M. C., Kulkarni, S. S. & Bennett, C. S., 25 Jan 2023, In: Frontiers in Chemistry. 11, 1144042.Research output: Contribution to journal › Editorial (Academic Journal)
Open Access -
AuCl3-Catalyzed Hemiacetal Activation for the Stereoselective Synthesis of 2-Deoxy Trehalose Derivatives
Jeanneret, R., Walz, C., van Meerbeek, M., Coppock, S. & Galan, M. C., 2 Sept 2022, In: Organic Letters. 24, 34, p. 6304-6309 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)31 Downloads (Pure)
Datasets
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Surface functionalisation significantly changes the physical and electronic properties of carbon nano-dots
Oliver, T. (Creator), Duchi, M. (Creator), Swift, T. (Creator) & Galan, M. C. (Creator), University of Bristol, 8 Jul 2018
DOI: 10.5523/bris.30s3i070zb0qv2tipisop5a1h4, http://data.bris.ac.uk/data/dataset/30s3i070zb0qv2tipisop5a1h4
Dataset
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Ultrafast Chemical Dynamics: Guanine-Cytosine Photochemistry
Coulter, P. (Creator), Roberts, G. (Creator), Grubb, M. (Creator), Orr-Ewing, A. J. (Creator), Marroux, H. (Creator), Roettger, K. (Creator), Roettger, K. (Contributor), Galan, M. C. (Contributor), Roberts, G. (Contributor), Marroux, H. (Contributor), Bohnke, H. (Contributor), Orr-Ewing, A. J. (Contributor), Henderson, A. (Contributor), Grubb, M. (Contributor), Coulter, P. (Contributor) & Temps, F. (Contributor), University of Bristol, 21 May 2015
DOI: 10.5523/bris.rql1plzevlth1oxdiuegc1reu, http://data.bris.ac.uk/data/dataset/rql1plzevlth1oxdiuegc1reu
Dataset
Activities
- 1 Fellowship awarded competitively
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Career Acceleration Fellowship - Novel ionic-based tools for glycoscience.
M C Galan (Recipient)
31 Mar 2012 → 31 Mar 2017Activity: Other activity types › Fellowship awarded competitively