Projects per year
In our lab we are interested in employing synthetic organic chemistry as a tool to probe and manipulate the structure and function of biologically relevant molecules to study biological problems and potentially discover treatments for diseases.
Carbohydrates have emerged as important factors of molecular recognition in biology and medicine. Understanding the roles of these complex molecules, which are found on the surface of cells as part of glycoproteins or glycolipids is of great importance. However, the synthesis of these oligosaccharide structures is still a challenging task.
Our current research interests focus on the development of new synthetic techniques for the facile synthesis of oligosaccharide libraries and glycoconjugates drug analogues.
We are also interested in the development of multivalent platforms to study carbohydrate-protein interactions in the context of disease.
Dr Galan is a supervisor in the EPSRC Centre for Doctoral Training in Chemical Synthesis
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1/01/21 → 31/12/22
Project: Research, Parent
Bio-Inspired Fluorescent Carbon Dots as probes for rapid detection of bacteria in physiological samples
1/10/19 → 30/09/23
A promiscuous glycosyltransferase generates poly-β-1,4-glucan derivatives that facilitate mass spectrometry-based detection of cellulolytic enzymesBulmer, G. S., Mattey, A. P., Parmeggiani, F., Williams, R., Ledru, H., Marchesi, A., Seibt, L. S., Both, P., Huang, K., Galan, M. C., Flitsch, S. L., Green, A. P. & van Munster, J. M., 7 Jul 2021, In: Organic and Biomolecular Chemistry. 19, 25, p. 5529-5533 5 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile1 Citation (Scopus)1 Downloads (Pure)
A Vibration-Induced-Emission-Based Fluorescent Chemosensor for the Selective and Visual Recognition of GlucoseRamos-Soriano, J., Benitez-Benitez, S., Davis, A. & Galan, M. C., 26 Jul 2021, In: Angewandte Chemie - International Edition. 60, 31, p. 16880-16884 5 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile2 Citations (Scopus)4 Downloads (Pure)
Ghirardello, M., Tastan, O. Y., Roustan, C., Choi, J., Galan, M. C., Schumann, B. & Malaker, S. A., 1 Sep 2021, In: Journal of the American Society for Mass Spectrometry. 32, 9, 10 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review
Surface functionalisation significantly changes the physical and electronic properties of carbon nano-dots
Coulter, P. (Creator), Roberts, G. (Creator), Grubb, M. (Creator), Orr-Ewing, A. J. (Creator), Marroux, H. (Creator), Roettger, K. (Creator), Roettger, K. (Contributor), Galan, M. C. (Contributor), Roberts, G. (Contributor), Marroux, H. (Contributor), Bohnke, H. (Contributor), Orr-Ewing, A. J. (Contributor), Henderson, A. (Contributor), Grubb, M. (Contributor), Coulter, P. (Contributor) & Temps, F. (Contributor), University of Bristol, 21 May 2015
- 1 Fellowship awarded competitively