M C Galan

2025

An organometallic approach to sub-2 nm thiolate-protected Au nanoclusters with enhanced catalytic and therapeutic properties

del-Campo, I., Sorroche, A., Allen, N., Ghirardello, M., Corzana, F., Galán, M. C., Monge, M. & López-de-Luzuriaga, J. M., 7 Jun 2025, In: Nanoscale Advances. 7, 11, p. 3228-3235 8 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

Expedient synthesis of mucin-type oligosaccharide analogues using alkynyl glycosyl carbonate donors

Rao, B. V., Johns, J. & Galan, M. C., 1 Jul 2025, In: Carbohydrate Research. 553, 9 p., 109497.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2024

C2-Linked Arabinose-Functionalized Polystyrene Microbeads Selectively Target Staphylococcus aureus

Walke, G., Santi, C., Haydon, C., Joshi, P., Takebayashi, Y., Rama, S., Dorh, J., Hotha, S., Spencer, J. & Galan, M. C., 25 Nov 2024, In: JACS Au. 4, 11, p. 4537-4543 7 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

1 Citation (Scopus)

DNA G-quadruplexes in the genome of Trypanosoma cruzi as potential therapeutic targets for Chagas disease: Dithienylethene ligands as effective antiparasitic agents

Pérez-Soto, M., Ramos-Soriano, J., Peñalver, P., Belmonte-Reche, E., O'Hagan, M. P., Cucchiarini, A., Mergny, J.-L., Galán, M. C., López López, M. C., Thomas, M. D. C. & Morales, J. C., 5 Oct 2024, In: European Journal of Medicinal Chemistry. 276, 116641.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2 Citations (Scopus)

High sensitivity profiling of N-glycans from mouse serum using fluorescent imidazolium tags by HILIC electrospray ionisation spectrometry

Zhang, Y.-Y., Zhang, S.-Y., Hu, Z.-X., Voglmeir, J., Liu, L., Galan, M. C. & Ghirardello, M., 1 Nov 2024, In: Carbohydrate Polymers. 343, 9 p., 122449.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

1 Citation (Scopus)

Hypervalent Iodine Compounds in Carbohydrate Chemistry: Glycosylation, Functionalization and Oxidation

Mahanti, M., Pal, K. B., Wallentin, C. J. & Galan, M. C., 2 May 2024, In: Chemistry - A European Journal. 30, 25, e202400087.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

4 Citations (Scopus)

Microfluidics-Based Ionic Catch and Release Oligosaccharide Synthesis (ICROS-Microflow) to Expedite Glycosylation Chemistry

Zhang, Y.-Y., Ghirardello, M., Williams, R., Diaz, A. S., Rojo, J., Voglmeir, J., Ramos-Soriano, J. & Galan, M. C., 21 Oct 2024, (E-pub ahead of print) In: JACS Au. 4, 11, p. 4328-4333 6 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2 Citations (Scopus)

Probing the binding and antiparasitic efficacy of azobenzene G-quadruplex ligands to investigate G4 ligand design

Ramos-Soriano, J., Holbrow-Wilshaw, M., Hunt, E., Jiang, Y. J., Peñalver, P., Morales, J. C. & Galan, M. C., 8 Oct 2024, In: Chemical communications (Cambridge, England). 60, 81, p. 11520-11523 4 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

1 Citation (Scopus)

Synthesis and screening of a library of Lewis^x deoxyfluoro-analogues reveals differential recognition by glycan-binding partners

Hollingsworth, K., Di Maio, A., Richards, S.-J., Vendeville, J.-B., Wheatley, D. E., Council, C. E., Keenan, T., Ledru, H., Chidwick, H., Huang, K., Parmeggiani, F., Marchesi, A., Chai, W., McBerney, R., Kamiński, T. P., Balmforth, M. R., Tamasanu, A., Finnigan, J. D., Young, C. & Warriner, S. L. & 9 others, Webb, M. E., Fascione, M. A., Flitsch, S., Galan, M. C., Feizi, T., Gibson, M. I., Liu, Y., Turnbull, W. B. & Linclau, B., 13 Sept 2024, In: Nature Communications. 15, 1, 14 p., 7925.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

3 Citations (Scopus)

2023

Diphosphine Bioconjugates via Pt(0)-Catalyzed Hydrophosphination. A Versatile Chelator Platform for Technetium-99m and Rhenium-188 Radiolabeling of Biomolecules

Nuttall, R. E., Pham, T. T., Chadwick, A. C., Hungnes, I. N., Firth, G., Heckenast, M. A., Sparkes, H. A., Galan, M. C., Ma, M. T. & Pringle, P. G., 31 Jan 2023, (E-pub ahead of print) In: Inorganic Chemistry. 62, 50, p. 20582-20592 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

7 Citations (Scopus)

Editorial: Recent advances in carbohydrate chemical and enzymatic syntheses

Galan, M. C., Kulkarni, S. S. & Bennett, C. S., 25 Jan 2023, In: Frontiers in Chemistry. 11, 1144042.

Research output: Contribution to journal › Editorial (Academic Journal)

Open Access

1 Citation (Scopus)

Multicolor Photoluminescent Carbon Dots à La Carte for Biomedical Applications

Garcia-Millan, T., Ramos-Soriano, J., Ghirardello, M., Liu, X., Santi, C. M., Eloi, J.-C., Pridmore, N., Harniman, R. L., Morgan, D. J., Hughes, S., Davis, S. A., Oliver, T. A. A., Kurian, K. M. & Galan, M. C., 27 Sept 2023, In: ACS Applied Materials & Interfaces. 15, 38, p. 44711-44721 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

8 Citations (Scopus)

Reverse thiophosphorylase activity of a glycoside phosphorylase in the synthesis of an unnatural Manβ1,4GlcNAc library

Keenan, T., Hatton, N. E., Porter, J., Vendeville, J.-B., Wheatley, D. E., Ghirardello, M., Wahart, A. J. C., Ahmadipour, S., Walton, J., Galan, M. C., Linclau, B., Miller, G. J. & Fascione, M. A., 1 Nov 2023, In: Chemical Science. 14, 42, p. 11638-11646 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

3 Citations (Scopus)

2022

AuCl3-Catalyzed Hemiacetal Activation for the Stereoselective Synthesis of 2-Deoxy Trehalose Derivatives

Jeanneret, R., Walz, C., van Meerbeek, M., Coppock, S. & Galan, M. C., 2 Sept 2022, In: Organic Letters. 24, 34, p. 6304-6309 6 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

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6 Citations (Scopus)

155 Downloads (Pure)

Carbon-based glyco-nanoplatforms: towards the next generation of glycan-based multivalent probes

Ramos-Soriano, J., Ghirardello, M. & Galan, M. C., 23 Nov 2022, (E-pub ahead of print) In: Chemical Society Reviews. 51, 24, p. 9960-9985 26 p.

Research output: Contribution to journal › Review article (Academic Journal) › peer-review

Open Access

18 Citations (Scopus)

Carbon dot-based fluorescent antibody nanoprobes as brain tumour glioblastoma diagnostics

Ghirardello, M., Shyam, R., Liu, X., Garcia-Millan, T., Sittel, I., Ramos-Soriano, J., Kurian, K. M. & Galan, M. C., 29 Mar 2022, In: Nanoscale Advances. 4, 7, p. 1770-1778 9 p.

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14 Citations (Scopus)

50 Downloads (Pure)

Green Fluorescent Carbon Dots as Targeting Probes for LED-Dependent Bacterial Killing

Samphire, J. L., Takebayashi, Y., Hill, S. A., Hill, N., Heesom, K. J., Lewis, P. A., Alibhai, D. R., Spencer, J. & Galan, M. C., 1 Mar 2022, In: Nano Select. 3, 3, p. 662-672

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142 Downloads (Pure)

Measuring the Refractive Index and Sub-Nanometre Surface Functionalisation of Nanoparticles in Suspension

Mulkerns, N., Hoffmann, W. H., Ramos Soriano, F. J., de la Cruz, N., Garcia Millan, T., Harniman, R. L., Lindsay, I. D., Seddon, A. M., Galan, M. C. & Gersen, H., 9 Jun 2022, In: Nanoscale. 14, 22, p. 8145-8152 8 p.

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6 Citations (Scopus)

111 Downloads (Pure)

Recent applications of ionic liquid-based tags in glycoscience

Ghirardello, M., Zhang, Y.-Y., Voglmeir, J. & Galan, M. C., 1 Oct 2022, In: Carbohydrate Research. 520, 12 p., 108643.

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9 Citations (Scopus)

71 Downloads (Pure)

Reengineering of cancer cell surface charges can modulate cell migration

Ghirardello, M., Shyam, R. & Galan, M. C., 3 May 2022, In: Chemical communications (Cambridge, England). 58, 36, p. 5522-5525 4 p.

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9 Citations (Scopus)

33 Downloads (Pure)

Small variations in reaction conditions tune carbon dot fluorescence

Garcia Millan, T., Swift, T. A., Morgan, D. J., Harniman, R. L., Masheder, B., Hughes, S., Davis, S. A., Oliver, T. A. A. & Galan, M. C., 14 May 2022, In: Nanoscale. 14, 18, p. 6930–6940 11 p.

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18 Citations (Scopus)

66 Downloads (Pure)

Structure-activity relationship studies on divalent naphthalene diimide G quadruplex ligands with anticancer and antiparasitic activity

Pérez-Soto, M., Peñalver, P., Street, S. T. G., Weenink, D., O'Hagan, M. P., Ramos-Soriano, J., Jiang, Y. J., Hollingworth, G. J., Galan, M. C. & Morales, J. C., 26 Jul 2022, (E-pub ahead of print) In: Bioorganic & Medicinal Chemistry. 71, 116946.

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12 Citations (Scopus)

148 Downloads (Pure)

Synthesis of 2-deoxy mucin-type O-glycan analogues as biological probes

Johnson, S. E. & Galan, M. C., 1 Apr 2022, In: Carbohydrate Research. 514, p. 108542 9 p., 108542.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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2 Citations (Scopus)

34 Downloads (Pure)

2021

A promiscuous glycosyltransferase generates poly-β-1,4-glucan derivatives that facilitate mass spectrometry-based detection of cellulolytic enzymes

Bulmer, G. S., Mattey, A. P., Parmeggiani, F., Williams, R., Ledru, H., Marchesi, A., Seibt, L. S., Both, P., Huang, K., Galan, M. C., Flitsch, S. L., Green, A. P. & van Munster, J. M., 7 Jul 2021, In: Organic and Biomolecular Chemistry. 19, 25, p. 5529-5533 5 p.

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8 Citations (Scopus)

45 Downloads (Pure)

A Vibration-Induced-Emission-Based Fluorescent Chemosensor for the Selective and Visual Recognition of Glucose

Ramos-Soriano, J., Benitez-Benitez, S., Davis, A. & Galan, M. C., 26 Jul 2021, In: Angewandte Chemie - International Edition. 60, 31, p. 16880-16884 5 p.

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58 Citations (Scopus)

92 Downloads (Pure)

Benefits of Chemical Sugar Modifications Introduced by Click Chemistry for Glycoproteomic Analyses

Calle, B., Bineva-Todd, G., Marchesi, A., Flynn, H., Ghirardello, M., Tastan, O. Y., Roustan, C., Choi, J., Galan, M. C., Schumann, B. & Malaker, S. A., 1 Sept 2021, In: Journal of the American Society for Mass Spectrometry. 32, 9, p. 2366-2375 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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26 Citations (Scopus)

73 Downloads (Pure)

Carbon Dots as an Emergent Class of Antimicrobial Agents

Ghirardello, M., Ramos-Soriano, J. & Galan, M. C., Aug 2021, In: Nanomaterials. 11, 8, 1877.

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117 Citations (Scopus)

298 Downloads (Pure)

Fast identification and quantification of uropatho-genic E. coli through cluster analysis

Vendeville, J.-B., Kyriakides, M. J., Takebayashi, Y., Dorh, J. N., Spencer, J. & Galan, M. C., 13 Dec 2021, (E-pub ahead of print) In: ACS Biomaterials Science and Engineering. 8, 1, 242–252.

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2 Citations (Scopus)

221 Downloads (Pure)

Functional Glyconanomaterials

Palomo, J. M., Galan, M. C. & Garcia-Fernandez, J. M., Oct 2021, In: Nanomaterials. 11, 10, 2482.

Research output: Contribution to journal › Editorial (Academic Journal)

Open Access

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1 Citation (Scopus)

63 Downloads (Pure)

Glioma stem-like cells and metabolism: Potential for novel therapeutic strategies

Harland, A. J., Liu, X., Ghirardello, M., Galan, M. C., Perks, C. M. & Kurian, K. M., 31 Aug 2021, In: Frontiers in Oncology. 11, 743814.

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16 Citations (Scopus)

100 Downloads (Pure)

Imidazolium labelling permits the sensitive mass-spectrometric detection of N-glycosides directly from serum

Zhang, Y.-Y., Ghirardello, M., Wang, T., Lu, A.-M., Liu, L., Voglmeir, J. & Galan, M. C., 21 Jul 2021, In: Chemical communications (Cambridge, England). 57, 57, p. 7003-7006 4 p.

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8 Citations (Scopus)

41 Downloads (Pure)

Imide Condensation as a Strategy for the Synthesis of Core-diversified G-quadruplex Ligands with Anti-cancer and Anti-parasitic Activity

Street, S., Peñalver, P., O'Hagan, M., Hollingworth, G., Morales, J. C. & Galan, M. C., 17 May 2021, In: Chemistry - A European Journal. 27, 28, p. 7712-7721 10 p.

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11 Citations (Scopus)

73 Downloads (Pure)

Photoresponsive Control of G-Quadruplex DNA Systems

Ramos-Soriano, J. & Galan, M. C., 25 Oct 2021, In: JACS Au. 1, 10, p. 1516-1526 11 p.

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29 Citations (Scopus)

86 Downloads (Pure)

Recent advances in multivalent carbon nanoform-based glycoconjugates

Ramos-Soriano, J., Ghirardello, M. & Galan, M. C., 14 Jul 2021, (E-pub ahead of print) In: Current Medicinal Chemistry.

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6 Citations (Scopus)

117 Downloads (Pure)

Synthetic Mechanism Studies of Iron Selenides: An Emerging Class of Materials for Electrocatalysis

Fermin, D. J., Hou, B., Benito-Alifonso, D., Webster, R., Cherns, D. & Galan, M. C., 27 May 2021, In: Catalysts. 11, 6, 681.

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12 Citations (Scopus)

131 Downloads (Pure)

The Roy L. Whistler International Award in Carbohydrate Chemistry 2022

Rauter, A. P. & Galan, M. C., Nov 2021, In: Carbohydrate Research. 509, p. 108420 108420.

Research output: Contribution to journal › Editorial (Academic Journal)

2020

Biocatalytic Transfer of Pseudaminic Acid (Pse5Ac7Ac) Using Promiscuous Sialyltransferases in a Chemoenzymatic Approach to Pse5Ac7Ac-Containing Glycosides

Flack, E. K. P., Chidwick, H. S., Guchhait, G., Keenan, T., Budhadev, D., Huang, K., Both, P., Mas Pons, J., Ledru, H., Rui, S., Stafford, G. P., Shaw, J. G., Galan, M. C., Flitsch, S., Thomas, G. H. & Fascione, M. A., 4 Sept 2020, In: ACS Catalysis. 10, 17, p. 9986-9993 8 p.

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11 Citations (Scopus)

63 Downloads (Pure)

Biochemical characterisation of an α1,4 galactosyltransferase from Neisseria weaveri for the synthesis of α1,4-linked galactosides

Huang, K., Marchesi, A., Hollingsworth, K., Both, P., Mattey, A. P., Pallister, E., Ledru, H., Charnock, S. J., Galan, M. C., Turnbull, W. B., Parmeggiani, F. & Flitsch, S. L., 30 Mar 2020, In: Organic and Biomolecular Chemistry. 18, 16, p. 3142-3148 7 p.

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10 Citations (Scopus)

8 Downloads (Pure)

Chemoenzymatic synthesis of 3-deoxy-3-fluoro-l-fucose and its enzymatic incorporation into glycoconjugates

Valverde, P., Vendeville, J.-B., Hollingsworth, K., Mattey, A. P., Keenan, T., Chidwick, H., Ledru, H., Huonnic, K., Huang, K., Light, M. E., Turner, N., Jiménez-Barbero, J., Galan, M. C., Fascione, M. A., Flitsch, S., Turnbull, W. B. & Linclau, B., 29 Apr 2020, (E-pub ahead of print) In: Chemical communications (Cambridge, England). (2020) 56, p. 6408-6411

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13 Citations (Scopus)

60 Downloads (Pure)

Chemo-selective Rh-catalysed hydrogenation of azides into amines

Ghirardello, M., Ledru, H., Sau, A. & Galan, M. C., 1 Mar 2020, In: Carbohydrate Research. 489, p. 107948 4 p.

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5 Citations (Scopus)

261 Downloads (Pure)

Conformationally Constrained Glycosyl Donors as Tools to Control Glycosylation Outcomes

Jeanneret, R. A., Johnson, S. E. & Galan, M. C., 26 Oct 2020, (E-pub ahead of print) In: Journal of Organic Chemistry. (2020), 26 p.

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36 Citations (Scopus)

34 Downloads (Pure)

Copper Reactivity Can Be Tuned to Catalyze the Stereoselective Synthesis of 2-Deoxyglycosides from Glycals

Palo-Nieto, C., Sau, A., Jeanneret, R., Payard, P.-A., Salamé, A., Martins-Teixeira, M. B., Carvalho, I., Grimaud, L. & Galan, M. C., 6 Mar 2020, In: Organic Letters. 22, 5

Research output: Contribution to journal › Article (Academic Journal) › peer-review

31 Citations (Scopus)

Cytotoxic (cis,cis-1,3,5-triaminocyclohexane)ruthenium(II)-diphosphine complexes; evidence for covalent binding and intercalation with DNA

Wise, D. E., Gamble, A. J., Arkawazi, S. W., Walton, P. H., Galan, M. C., O'Hagan, M. P., Hogg, K. G., Marrison, J. L., O'Toole, P. J., Sparkes, H. A., Lynam, J. M. & Pringle, P. G., 6 Oct 2020, (E-pub ahead of print) In: Dalton Transactions.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

4 Citations (Scopus)

Effect of acoustic standing waves on cellular viability and metabolic activity

Galan, M. C., Levario Diaz, V., Barnes, A. C. & Bhaskar, P., 2020, In: Scientific Reports. 11 p., 8493 (2020).

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8 Citations (Scopus)

144 Downloads (Pure)

Enhanced sampling molecular dynamics simulations correctly predict the diverse activities of a series of stiff-stilbene G-quadruplex DNA ligands

O'Hagan, M. P., Haldar, S., Morales, J. C., Mulholland, A. J. & Galan, M. C., 26 Nov 2020, In: Chemical Science. 12, 4, p. 1415-1426 12 p., 1415-1426.

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22 Citations (Scopus)

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Introducing affinity and selectivity into galectin-targeting nanoparticles with fluorinated glycan ligands

Richards, S.-J., Keenan, T., Vendeville, J.-B., Wheatley, D. E., Chidwick, H., Budhadev, D., Council, C. E., Webster, C. S., Ledru, H., Baker, A. N., Walker, M., Galan, M. C., Linclau, B., Fascione, M. A. & Gibson, M. I., 16 Nov 2020, In: Chemical Science. 12, 3, p. 905-910 6 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

26 Citations (Scopus)

Introduction to Glycosylation: new methodologies and applications

Fairbanks, A. J., Flitsch, S. L. & Galan, M. C., 23 Sept 2020, In: Organic and Biomolecular Chemistry. 18, 36, p. 6979-6982 4 p.

Research output: Contribution to journal › Editorial (Academic Journal)

7 Citations (Scopus)

Norbornene-Functionalized Chitosan Hydrogels and Microgels via Unprecedented Photoinitiated Self-Assembly for Potential Biomedical Applications

Michel, S. S. E., Kilner, A., Eloi, J.-C., Rogers, S. E., Briscoe, W. H. & Galan, M. C., 17 Aug 2020, In: ACS Applied Bio Materials.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

19 Citations (Scopus)

Photosynthesis and crop productivity are enhanced by glucose-functionalized carbon dots

Swift, T., Fagan, D., Benito-Alifonso, D., Hill, S. A., Yallop, M. L., Lawson, T., Oliver, T. A. A., Galan, M. C. & Whitney, H. M., 19 Aug 2020, In: New Phytologist.

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46 Citations (Scopus)

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Pseudo-enantiomeric carbohydrate-based N-heterocyclic carbenes as promising chiral ligands for enantiotopic discrimination

Henderson, A. S., Bower, J. F. & Galan, M. C., 29 Apr 2020, In: Organic and Biomolecular Chemistry. 18, 16, p. 3012-3016 5 p.

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8 Citations (Scopus)

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Professor M C Galan

Research output

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