Dr M U B St Pourcain

M.Sc., Ph.D.(Cardiff)

  • BS8 2BN

20052020

Research output per year

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Research Output

  • 117 Article (Academic Journal)
  • 2 Letter (Academic Journal)
  • 1 Comment/debate (Academic Journal)
2020

The genetic architecture of the human cerebral cortex

Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)-Genetics working group, 20 Mar 2020, In : Science. 367, 6484, aay6690.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
19 Citations (Scopus)
2019

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

the 23 and Me Research Team, ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, Demontis, D., Walters, R. K., Martin, J., Mattheisen, M., Als, T. D., Agerbo, E., Baldursson, G., Belliveau, R., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Cerrato, F., Chambert, K., Churchhouse, C., Dumont, A., Eriksson, N., Gandal, M., Goldstein, J. I. & 33 others, Grasby, K. L., Grove, J., Gudmundsson, O. O., Hansen, C. S., Hauberg, M. E., Hollegaard, M. V., Howrigan, D. P., Huang, H., Maller, J. B., Martin, A. R., Martin, N. G., Moran, J., Pallesen, J., Palmer, D. S., Pedersen, C. B., Pedersen, M. G., Poterba, T., Poulsen, J. B., Ripke, S., Robinson, E. B., Satterstrom, F. K., Smith, G. D., Davies, G. E., Evans, D. M., Kemp, J. P., Ring, S., Stergiakouli, E., Pourcain, B. S., Stoltenberg, C., Timpson, N. J., Langley, K., Thapar, A. & Medland, S. E., 1 Jan 2019, In : Nature Genetics. 51, 1, p. 63-75 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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241 Citations (Scopus)
192 Downloads (Pure)

Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language

iPSYCH-Broad-PGC ADHD Consortium, Verhoef, E., Demontis, D., Burgess, S., Shapland, C. Y., Dale, P. S., Okbay, A., Neale, B. M., Faraone, S. V., Stergiakouli, E., Davey Smith, G., Fisher, S. E., Børglum, A. D. & St Pourcain, B., 24 Jan 2019, In : Translational Psychiatry. 9, 1, p. 35 12 p., 35.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
181 Downloads (Pure)

Evidence for DNA methylation mediating genetic liability to non-syndromic cleft lip/palate

Howe, L., Richardson, T., Arathimos, R., Alvizi, L., Passos-Bueno, M. R., Stanier, P., Nohr, E. A., Ludwig, K., Mangold, E., Knapp, M., Stergiakouli, E., St Pourcain, B., Davey Smith, G., Sandy, J., Relton, C., Lewis, S., Hemani, G. & Sharp, G., 1 Feb 2019, In : Epigenomics. 11, 2, p. 133-145 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
161 Downloads (Pure)

Genetic evidence for assortative mating on alcohol consumption in the UK Biobank

Howe, L. J., Lawson, D. J., Davies, N. M., St. Pourcain, B., Lewis, S. J., Davey Smith, G. & Hemani, G., 19 Nov 2019, In : Nature Communications. 10, 10 p., 5039 (2019).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
128 Downloads (Pure)

Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia

Gialluisi, A., Andlauer, T. F. M., Mirza-Schreiber, N., Moll, K., Becker, J., Hoffmann, P., Ludwig, K. U., Czamara, D., St Pourcain, B., Brandler, W., Honbolygó, F., Tóth, D., Csépe, V., Huguet, G., Morris, A. P., Hulslander, J., Willcutt, E. G., DeFries, J. C., Olson, R. K., Smith, S. D. & 25 others, Pennington, B. F., Vaessen, A., Maurer, U., Lyytinen, H., Peyrard-Janvid, M., Leppänen, P. H. T., Brandeis, D., Bonte, M., Stein, J. F., Talcott, J. B., Fauchereau, F., Wilcke, A., Francks, C., Bourgeron, T., Monaco, A. P., Ramus, F., Landerl, K., Kere, J., Scerri, T. S., Paracchini, S., Fisher, S. E., Schumacher, J., Nöthen, M. M., Müller-Myhsok, B. & Schulte-Körne, G., 1 Dec 2019, In : Translational Psychiatry. 9, 15 p., 77.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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8 Citations (Scopus)
220 Downloads (Pure)

Identification of common genetic risk variants for autism spectrum disorder

Grove, J., Ripke, S., Als, T. D., Mattheisen, M., Walters, R. K., Won, H., Pallesen, J., Agerbo, E., Andreassen, O. A., Anney, R., Awashti, S., Belliveau, R., Bettella, F., Buxbaum, J. D., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Cerrato, F., Chambert, K., Christensen, J. H., Churchhouse, C. & 24 others, Dellenvall, K., Demontis, D., De Rubeis, S., Devlin, B., Djurovic, S., Dumont, A. L., Goldstein, J. I., Hansen, C. S., Hauberg, M. E., Hollegaard, M. V., Hope, S., Howrigan, D. P., Huang, H., Hultman, C. M., Klei, L., Maller, J., Martin, J., Pedersen, C. B., Davey Smith, G., Pourcain, B. S., Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & the 23 and Me Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 431-444 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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151 Citations (Scopus)
695 Downloads (Pure)

Investigating genetic links between grapheme-colour synaesthesia and neuropsychiatric traits

Tilot, A. K., Vino, A., Kucera, K. S., Carmichael, D. A., van den Heuvel, L., den Hoed, J., Sidoroff-Dorso, A. V., Campbell, A., Porteous, D. J., St Pourcain, B., van Leeuwen, T. M., Ward, J., Rouw, R., Simner, J. & Fisher, S. E., 9 Dec 2019, In : Philosophical Transactions B: Biological Sciences. 374, 1787, 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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93 Downloads (Pure)

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Haworth, S., Shapland, C. Y., Hayward, C., Prins, B. P., Felix, J. F., Medina-Gomez, C., Rivadeneira, F., Wang, C., Ahluwalia, T. S., Vrijheid, M., Guxens, M., Sunyer, J., Tachmazidou, I., Walter, K., Iotchkova, V., Jackson, A., Cleal, L., Huffmann, J., Min, J. L., Sass, L. & 7 others, Timmers, P. R. H. J., UK10K Consortium, Davey Smith, G., Cole, T. J., Timpson, N., Zeggini, E. & St Pourcain, B., 21 Jan 2019, In : Nature Communications. 10, 16 p., 357.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
111 Downloads (Pure)

Neandertal Introgression Sheds Light on Modern Human Endocranial Globularity

Gunz, P., Tilot, A. K., Wittfeld, K., Teumer, A., Shapland, C. Y., van Erp, T. G. M., Dannemann, M., Vernot, B., Neubauer, S., Guadalupe, T., Fernández, G., Brunner, H. G., Enard, W., Fallon, J., Hosten, N., Völker, U., Profico, A., Di Vincenzo, F., Manzi, G., Kelso, J. & 7 others, St. Pourcain, B., Hublin, J. J., Franke, B., Pääbo, S., Macciardi, F., Grabe, H. J. & Fisher, S. E., 7 Jan 2019, In : Current Biology. 29, 1, p. 120-127.e5 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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16 Citations (Scopus)
108 Downloads (Pure)

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) Consortia: design, results and future prospects

Middeldorp, C. M., Felix, J. F., Mahajan, A., Early Genetics and Lifecourse Epidemiology (EAGLE) Consortium, Early Growth Genetics (EGG) Consortium, McCarthy, M. I. & Paternoster, L., Mar 2019, In : European Journal of Epidemiology. 34, 3, p. 279-300 22 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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164 Downloads (Pure)
2018

ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties

St Pourcain, B., Robinson, E., Anttila, V., Bulik Sullivan, B., Maller, J., Golding, J., Skuse, D., Ring, S., Evans, D., Zammit, S., Fisher, S., Neale, B., Anney, R., Ripke, S., Hollegaard, M., Werge, T., Ronald, A., Grove, J., Hougaard, D., Borglum, A. & 3 others, Mortensen, P. B., Daly, M. & Davey Smith, G., Feb 2018, In : Molecular Psychiatry. 23, 2, p. 263-270 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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34 Citations (Scopus)
231 Downloads (Pure)

Developmental Changes Within the Genetic Architecture of Social Communication Behavior: A Multivariate Study of Genetic Variance in Unrelated Individuals

St Pourcain, B., Eaves, L. J., Ring, S. M., Fisher, S. E., Medland, S., Evans, D. M. & Davey Smith, G., 1 Apr 2018, In : Biological Psychiatry. 83, 7, p. 598-606 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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8 Citations (Scopus)
165 Downloads (Pure)

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Ligthart, S., LifeLines Cohort Study, CHARGE Inflammation Working Group, Vaez, A., Võsa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., Van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Wu, Y., Karlsson, R., Barbalic, M., Lin, H., Pool, R., Zhu, G., Macé, A., Sidore, C. & 32 others, Trompet, S., Mangino, M., Sabater-Lleal, M., Kemp, J. P., Abbasi, A., Kacprowski, T., Verweij, N., Smith, A. V., Huang, T., Marzi, C., Feitosa, M. F., Lohman, K. K., Kleber, M. E., Milaneschi, Y., Mueller, C., Huq, M., Vlachopoulou, E., Lyytikäinen, L. P., Oldmeadow, C., Deelen, J., Perola, M., Zhao, J., Davey-Smith, G., Hicks, A., Timpson, N., St. Pourcain, B., Soranzo, N., Paternoster, L., Evans, D. M., Hicks, A., Palmer, L. J. & Davey-Smith, G., 1 Nov 2018, In : American Journal of Human Genetics. 103, 5, p. 691-706 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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31 Citations (Scopus)
109 Downloads (Pure)

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

The CREAM Consortium, the 23 and Me Research Team, UK Biobank Eye and Vision Consortium & Tedja, M. S., Jun 2018, In : Nature Genetics. 50, 6, p. 834-848 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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55 Citations (Scopus)
223 Downloads (Pure)

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology

Howe, L. J., Lee, M. K., Sharp, G. C., Davey Smith, G., St Pourcain, B., Shaffer, J. R., Ludwig, K. U., Mangold, E., Marazita, M. L., Feingold, E., Zhurov, A., Stergiakouli, E., Sandy, J., Richmond, S., Weinberg, S. M., Hemani, G. & Lewis, S. J., 1 Aug 2018, In : PLoS Genetics. 14, 8, 18 p., e1007501.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
240 Downloads (Pure)

The development of autistic social traits across childhood and adolescence in males and females

Mandy, W., Pellicano, L., St Pourcain, B., Skuse, D. & Heron, J., 19 Apr 2018, In : Journal of Child Psychology and Psychiatry.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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17 Citations (Scopus)
194 Downloads (Pure)
2017

Association between Polygenic Risk Scores for Attention-Deficit Hyperactivity Disorder and Educational and Cognitive Outcomes in the General Population

Stergiakouli, E., Martin, J., Hamshere, M., Heron, J., St Pourcain, B., Timpson, N., Thapar, A. & Davey Smith, G., Apr 2017, In : International Journal of Epidemiology. 46, 2, p. 421–428 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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22 Citations (Scopus)
374 Downloads (Pure)

Genetic Overlap Between Schizophrenia and Developmental Psychopathology: Longitudinal and Multivariate Polygenic Risk Prediction of Common Psychiatric Traits During Development

Nivard, M. G., Gage, S. H., Hottenga, J. J., van Beijsterveldt, C. E. M., Abdellaoui, A., Bartels, M., Baselmans, B. M. L., Ligthart, L., Pourcain, B. S., Boomsma, D. I., Munafò, M. R. & Middeldorp, C. M., Nov 2017, In : Schizophrenia Bulletin. 43, 6, p. 1197-1207 11 p., sbx031.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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34 Citations (Scopus)
238 Downloads (Pure)

Joint developmental trajectories of internalizing and externalizing disorders between childhood and adolescence

Nivard, M. G., Lubke, G. H., Dolan, C. V., Evans, D., St Pourcain, M. U. B., Munafo, M. & Middeldorp, C. M., Aug 2017, In : Development and Psychopathology. 29, 3, p. 919-928 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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18 Citations (Scopus)
333 Downloads (Pure)

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

Zheng, J., Erzurumluoglu, M., Elsworth, B., Howe, L., Haycock, P., Hemani, G., Tansey, K., Laurin, C., St Pourcain, B., Warrington, N. M., Finucane, H., Price, A. L., Bulik-Sullivan, B., Anttila, V., Paternoster, L., Gaunt, T., Evans, D. & Neale, B. M., 15 Jan 2017, In : Bioinformatics. 33, 2, p. 272-279 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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299 Downloads (Pure)

Shared genetic influences between dimensional ASD and ADHD symptoms during child and adolescent development

Stergiakouli, E., Davey Smith, G., Martin, J., Skuse, D. H., Viechtbauer, W., Ring, S. M., Ronald, A., Evans, D. E., Fisher, S. E., Thapar, A. & St Pourcain, B., 4 Apr 2017, In : Molecular Autism. 8, 13 p., 18.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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20 Citations (Scopus)
244 Downloads (Pure)

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

Tachmazidou, I., Süveges, D., Min, J. L., Ritchie, G. R. S., Steinberg, J., Walter, K., Iotchkova, V., Schwartzentruber, J., Huang, J., Memari, Y., McCarthy, S., Crawford, A. A., Bombieri, C., Cocca, M., Farmaki, A-E., Gaunt, T. R., Jousilahti, P., Kooijman, M. N., Lehne, B., Malerba, G. & 84 others, Männistö, S., Matchan, A., Medina-Gomez, C., Metrustry, S. J., Nag, A., Ntalla, I., Paternoster, L., Rayner, N. W., Sala, C., Scott, W. R., Shihab, H. A., Southam, L., St Pourcain, B., Traglia, M., Trajanoska, K., Zaza, G., Zhang, W., Artigas, M. S., Bansal, N., Benn, M., Chen, Z., Danecek, P., Lin, W-Y., Locke, A., Luan, J., Manning, A. K., Mulas, A., Sidore, C., Tybjaerg-Hansen, A., Varbo, A., Zoledziewska, M., Finan, C., Hatzikotoulas, K., Hendricks, A. E., Kemp, J. P., Moayyeri, A., Panoutsopoulou, K., Szpak, M., Wilson, S. G., Boehnke, M., Cucca, F., Di Angelantonio, E., Langenberg, C., Lindgren, C., McCarthy, M. I., Morris, A. P., Nordestgaard, B. G., Scott, R. A., Tobin, M. D., Wareham, N. J., Burton, P., Chambers, J. C., Smith, G. D., Dedoussis, G., Felix, J. F., Franco, O. H., Gambaro, G., Gasparini, P., Hammond, C. J., Hofman, A., Jaddoe, V. W. V., Kleber, M., Kooner, J. S., Perola, M., Relton, C., Ring, S. M., Rivadeneira, F., Salomaa, V., Spector, T. D., Stegle, O., Toniolo, D., Uitterlinden, A. G., Barroso, I., Greenwood, C. M. T., Perry, J. R. B., Walker, B. R., Butterworth, A. S., Xue, Y., Durbin, R., Small, K. S., Soranzo, N., Timpson, N. J., Zeggini, E. & Bansal, N., 1 Jun 2017, In : American Journal of Human Genetics. 100, 6, p. 865-884 20 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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29 Citations (Scopus)
197 Downloads (Pure)
2016

A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Paediatric Cohorts

Middeldorp, C. M., Hammerschlag, A. R., Ouwens, K. G., Groen-Blokhuis, M. M., St. Pourcain, B., Greven, C. U., Pappa, I., Tiesler, C. M. T., Ang, W., Nolte, I. M., Vilor-Tejedor, N., Bacelis, J., Ebejer, J. L., Zhao, H., Davies, G. E., Ehli, E. A., Evans, D. M., Fedko, I. O., Guxens, M., Hottenga, J-J. & 31 others, Hudziak, J. J., Jugessur, A., Kemp, J. P., Krapohl, E., Martin, N. G., Murcia, M., Myhre, R., Ormel, J., Ring, S. M., Standl, M., Stergiakouli, E., Stoltenberg, C., Thiering, E., Timpson, N. J., Trzaskowski, M., van der Most, P. J., Wang, C., Nyholt, D. R., Medland, S. E., Neale, B., Jacobsson, B., Sunyer, J., Hartman, C. A., Whitehouse, A. J. O., Pennell, C. E., Heinrich, J., Plomin, R., Smith, G. D., Tiemeier, H., Posthuma, D. & Boomsma, D. I., Oct 2016, In : Journal of the American Academy of Child and Adolescent Psychiatry. 55, 10, p. 896-905.e6 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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57 Citations (Scopus)
170 Downloads (Pure)

Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium

Fan, Q., Pourcain, B. S., Evans, D., Timpson, N. J., McMahon, G., Guggenheim, J. A. & The CREAM Consortium, 13 May 2016, In : Scientific Reports. 6, 14 p., 25853.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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38 Citations (Scopus)
375 Downloads (Pure)

Common Genetic Variants Influence Whorls in Fingerprint Patterns

Ho, Y. Y. W., Evans, D. M., Montgomery, G. W., Henders, A. K., Kemp, J. P., Timpson, N. J., St Pourcain, B., Heath, A. C., Madden, P. A. F., Loesch, D. Z., McNevin, D., Daniel, R., Davey-Smith, G., Martin, N. G. & Medland, S. E., Apr 2016, In : Journal of Investigative Dermatology. 136, 4, p. 859-862 4 p.

Research output: Contribution to journalLetter (Academic Journal)

6 Citations (Scopus)

Erratum to: Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence

Pourcain, B. S., Haworth, C. M. A., Davis, O. S. P., Wang, K., Timpson, N. J., Evans, D. M., Kemp, J. P., Ronald, A., Price, T., Meaburn, E., Ring, S. M., Golding, J., Hakonarson, H., Plomin, R. & Smith, G. D., 14 Jun 2016, In : Human Genetics. 135, 8, p. 965–965 10 p.

Research output: Contribution to journalComment/debate (Academic Journal)

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

Robinson, E. B., St Pourcain, B., Anttila, V., Kosmicki, J. A., Bulik-Sullivan, B., Grove, J., Maller, J., Samocha, K. E., Sanders, S. J., Ripke, S., Martin, J., Hollegaard, M. V., Werge, T., Hougaard, D. M., Neale, B. M., Evans, D. M., Skuse, D., Mortensen, P. B., Børglum, A. D., Ronald, A. & 3 others, Smith, G. D., Daly, M. J. & iPSYCH-SSI-Broad Autism Group, May 2016, In : Nature Genetics. 48, 5, p. 552-555 4 p.

Research output: Contribution to journalArticle (Academic Journal)

157 Citations (Scopus)

Genome-wide association study identifies 74 loci associated with educational attainment

Okbay, A., St Pourcain, B., Evans, D., McMahon, G., Paternoster, L., Ring, S., Sorensen, T., Timpson, N., Davey Smith, G., Visscher, P. M., Koellinger, P. D., Cesarini, D. & Benjamin, D. J., 26 May 2016, In : Nature. 533, 7604, p. 539-542 4 p.

Research output: Contribution to journalLetter (Academic Journal)

Open Access
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437 Citations (Scopus)
192 Downloads (Pure)

International GWAS Consortium Identifies Novel Loci Associated with Blood Pressure in Children and Adolescents

Parmar, P. G., Taal, H. R., Timpson, N. J., Thiering, E., Lehtimäki, T., Marinelli, M., Lind, P. A., Howe, L. D., Verwoert, G., Aalto, V., Uitterlinden, A. G., Briollais, L., Evans, D. M., Wright, M. J., Newnham, J. P., Whitfield, J. B., Lyytikäinen, L-P., Rivadeneira, F., Boomsma, D. I., Viikari, J. & 19 others, Gillman, M. W., St Pourcain, B., Hottenga, J-J., Montgomery, G. W., Hofman, A., Kähönen, M., Martin, N. G., Tobin, M. D., Raitakari, O., Vioque, J., Jaddoe, V. W. V., Jarvelin, M-R., Beilin, L. J., Heinrich, J., van Duijn, C. M., Pennell, C. E., Lawlor, D. A., Palmer, L. J. & EArly Genetics and Lifecourse Epidemiology Consortium, 11 Mar 2016, In : Circulation: Cardiovascular Genetics.

Research output: Contribution to journalArticle (Academic Journal)

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

Fan, Q., Verhoeven, V. J. M., Wojciechowski, R., Barathi, V. A., Hysi, P. G., Guggenheim, J. A., Hohn, R., Vitart, V., Khawaja, A. P., Yamashiro, K., Hosseini, S. M., Lehtimaki, T., Lu, Y., Haller, T., Xie, J., Delcourt, C., Pirastu, M., Wedenoja, J., Gharahkhani, P., Venturini, C. & 134 others, Miyake, M., Hewitt, A. W., Guo, X., Mazur, J., Huffman, J. E., Williams, K. M., Polasek, O., Campbell, H., Rudan, I., Vatavuk, Z., Wilson, J. F., Joshi, P. K., McMahon, G., St Pourcain, B., Evans, D. M., Simpson, C. L., Schwantes-An, T. H., Igo, R. P., Mirshahi, A., Cougnard-Gregoire, A., Bellenguez, C., Blettner, M., Raitakari, O., Kahonen, M., Seppala, I., Zeller, T., Meitinger, T., Ried, J. S., Gieger, C., Portas, L., Van Leeuwen, E. M., Amin, N., Uitterlinden, A. G., Rivadeneira, F., Hofman, A., Vingerling, J. R., Wang, Y. X., Wang, X., Tai-Hui Boh, E., Ikram, M. K., Sabanayagam, C., Gupta, P., Tan, V., Zhou, L., Ho, C. E. H., Lim, WE., Beuerman, R. W., Siantar, R., Tai, E. S., Vithana, E., Mihailov, E., Khor, C. C., Hayward, C., Luben, R. N., Foster, P. J., Klein, B. E. K., Klein, R., Wong, H. S., Mitchell, P., Metspalu, A., Aung, T., Young, T. L., He, M., Parssinen, O., Van Duijn, C. M., Jin Wang, J., Williams, C., Jonas, J. B., Teo, Y. Y., MacKey, D. A., Oexle, K., Yoshimura, N., Paterson, A. D., Pfeiffer, N., Wong, T. Y., Baird, P. N., Stambolian, D., Wilson, J. E. B., Cheng, C-Y., Hammond, C. J., Klaver, C. C. W., Saw, S. M., Rahi, J. S., Korobelnik, J. F., Kemp, J. P., Timpson, N. J., Smith, G. D., Craig, J. E., Burdon, K. P., Fogarty, R. D., Iyengar, S. K., Chew, E., Janmahasatian, S., Martin, N. G., MacGregor, S., Xu, L., Schache, M., Nangia, V., Panda-Jonas, S., Wright, A. F., Fondran, J. R., Lass, J. H., Feng, S., Zhao, J. H., Khaw, K. T., Wareham, N. J., Rantanen, T., Kaprio, J., Pang, C. P., Chen, L. J., Tam, P. O., Jhanji, V., Young, A. L., Doring, A., Raffel, L. J., Cotch, M. F., Li, X., Yip, S. P., Yap, M. K. H., Biino, G., Vaccargiu, S., Fossarello, M., Fleck, B., Yazar, S., Tideman, J. W. L., Tedja, M., Deangelis, M. M., Morrison, M., Farrer, L., Zhou, X., Chen, W., Mizuki, N., Meguro, A. & Makela, K. M., 6 Apr 2016, In : Nature Communications. 7, 12 p., 11008.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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52 Citations (Scopus)
445 Downloads (Pure)

Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium

van den Berg, S. M., de Moor, M. H. M., Verweij, K. J. H., Krueger, R. F., Luciano, M., Arias Vasquez, A., Matteson, L. K., Derringer, J., Esko, T., Amin, N., Gordon, S. D., Hansell, N. K., Hart, A. B., Seppälä, I., Huffman, J. E., Konte, B., Lahti, J., Lee, M., Miller, M., Nutile, T. & 31 others, Tanaka, T., Teumer, A., Viktorin, A., Wedenoja, J., Abdellaoui, A., Abecasis, G. R., Adkins, D. E., Agrawal, A., Allik, J., Appel, K., Bigdeli, T. B., Busonero, F., Campbell, H., Costa, P. T., Smith, G. D., Davies, G., de Wit, H., Ding, J., Engelhardt, B. E., Eriksson, J. G., Fedko, I. O., Ferrucci, L., Franke, B., Giegling, I., Grucza, R., Kemp, J. P., Medland, S. E., St Pourcain, B., Timpson, N. J., Evans, D. M. & Generation Scotland, Mar 2016, In : Behavior Genetics. 46, 2, p. 170-182 13 p.

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49 Citations (Scopus)
148 Downloads (Pure)

Opportunities and Challenges in Establishing a Cohort Study: An Example From Cleft Lip/Palate Research in the United Kingdom

Stock, N. M., Humphries, K., Pourcain, B. S., Bailey, M., Persson, M., Ho, K. M., Ring, S., Marsh, C., Albery, L., Rumsey, N. & Sandy, J., 1 May 2016, In : Cleft Palate-Craniofacial Journal. 53, 3, p. 317-325 9 p.

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17 Citations (Scopus)
2015

A genome-wide association study of body mass index across early life and childhood

Warrington, N. M., Howe, L. D., Paternoster, L., Kaakinen, M., Herrala, S., Huikari, V., Wu, Y. Y., Kemp, J. P., Timpson, N. J., Pourcain, B. S., Davey Smith, G., Tilling, K., Jarvelin, M-R., Pennell, C. E., Evans, D. M., Lawlor, D. A., Briollais, L. & Palmer, L. J., 7 May 2015, In : International Journal of Epidemiology. 44, 2, p. 700-712 12 p.

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61 Citations (Scopus)

A novel common variant in DCST2 is associated with length in early life and height in adulthood

van der Valk, R. J. P., Kreiner-Møller, E., Kooijman, M. N., Guxens, M., Stergiakouli, E., Sääf, A., Bradfield, J. P., Geller, F., Hayes, M. G., Cousminer, D. L., Körner, A., Thiering, E., Curtin, J. A., Myhre, R., Huikari, V., Joro, R., Kerkhof, M., Warrington, N. M., Pitkänen, N., Ntalla, I. & 31 others, Horikoshi, M., Veijola, R., Freathy, R. M., Teo, Y-Y., Barton, S. J., Evans, D. M., Kemp, J. P., St Pourcain, B., Ring, S. M., Davey Smith, G., Bergström, A., Kull, I., Hakonarson, H., Mentch, F. D., Bisgaard, H., Chawes, B., Stokholm, J., Waage, J., Eriksen, P., Sevelsted, A., Melbye, M., van Duijn, C. M., Medina-Gomez, C., Hofman, A., de Jongste, J. C., Taal, H. R., Uitterlinden, A. G., Murray, C. S., Holloway, J. W., Timpson, N. J. & Early Genetics and Lifecourse Epidemiology (EAGLE) Consortium, 15 Feb 2015, In : Human Molecular Genetics. 24, 4, p. 1155-1168 14 p.

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49 Citations (Scopus)

Assumption-free estimation of the genetic contribution to refractive error across childhood

Guggenheim, J. A., St Pourcain, B., McMahon, G., Timpson, N. J., Evans, D. M. & Williams, C., 2015, In : Molecular Vision. 21, p. 621-32 12 p.

Research output: Contribution to journalArticle (Academic Journal)

25 Citations (Scopus)

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

Li, Q., Wojciechowski, R., Simpson, C. L., Hysi, P. G., Verhoeven, V. J. M., Höhn, R., Vitart, V., Hewitt, A. W., Oexle, K., Mäkelä, K-M., MacGregor, S., Pirastu, M., Fan, Q., Cheng, C-Y., St Pourcain, B., McMahon, G., Kemp, J. P., Northstone, K., Rahi, J. S., Cumberland, P. M. & 28 others, Martin, N. G., Sanfilippo, P. G., Lu, Y., Wang, Y. X., Hayward, C., Polašek, O., Campbell, H., Bencic, G., Wedenoja, J., Zeller, T., Schillert, A., Mirshahi, A., Lackner, K., Yip, S. P., Yap, M. K. H., Ried, J. S., Gieger, C., Murgia, F., Fleck, B., Yazar, S., Vingerling, J. R., Timpson, N. J., Evans, D. M., Mitchell, P., Williams, C., Paterson, A. D., Guggenheim, J. A. & The CREAM Consortium, Feb 2015, In : Human Genetics. 134, 2, p. 131-46 16 p.

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15 Citations (Scopus)

Genome-wide association study of blood lead shows multiple associations near ALAD

Warrington, N. M., Zhu, G., Dy, V., Heath, A. C., Madden, P. A. F., Hemani, G., Kemp, J. P., Mcmahon, G., St Pourcain, B., Timpson, N. J., Taylor, C. M., Golding, J., Lawlor, D. A., Steer, C., Montgomery, G. W., Martin, N. G., Davey Smith, G., Evans, D. M. & Whitfield, J. B., 1 Jul 2015, In : Human Molecular Genetics. 24, 13, p. 3871-9 9 p.

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13 Citations (Scopus)

Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence

St Pourcain, B., Haworth, C. M. A., Davis, O. S. P., Wang, K., Timpson, N. J., Evans, D. M., Kemp, J. P., Ronald, A., Price, T., Meaburn, E., Ring, S. M., Golding, J., Hakonarson, H., Plomin, R. & Davey Smith, G., Jun 2015, In : Human Genetics. 134, 6, p. 539-551 13 p.

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7 Citations (Scopus)
393 Downloads (Pure)

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

de Moor, M. H. M., van den Berg, S. M., Verweij, K. J. H., Krueger, R. F., Luciano, M., Arias Vasquez, A., Matteson, L. K., Derringer, J., Esko, T., Amin, N., Gordon, S. D., Hansell, N. K., Hart, A. B., Seppälä, I., Huffman, J. E., Konte, B., Lahti, J., Lee, M., Miller, M., Nutile, T. & 30 others, Tanaka, T., Teumer, A., Viktorin, A., Wedenoja, J., Abecasis, G. R., Adkins, D. E., Agrawal, A., Allik, J., Appel, K., Bigdeli, T. B., Busonero, F., Campbell, H., Costa, P. T., Davey Smith, G., Davies, G., de Wit, H., Ding, J., Engelhardt, B. E., Eriksson, J. G., Fedko, I. O., Ferrucci, L., Franke, B., Giegling, I., Grucza, R., Kemp, J. P., Medland, S. E., St Pourcain, B., Timpson, N. J., Evans, D. M. & Genetics of Personality Consortium, 20 May 2015, In : JAMA Psychiatry.

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133 Citations (Scopus)

Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) traits in children and clinical ADHD

Stergiakouli, E., Martin, J., Hamshere, M. L., Langley, K., Evans, D. M., St Pourcain, B., Timpson, N. J., Owen, M. J., O'Donovan, M., Thapar, A. & Davey Smith, G., Apr 2015, In : Journal of the American Academy of Child and Adolescent Psychiatry. 54, 4, p. 322-7 6 p.

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47 Citations (Scopus)

The UK10K project identifies rare variants in health and disease

UK10K Consortium, Walter, K., Min, J. L., Huang, J., Crooks, L., Memari, Y., McCarthy, S., Perry, J. R. B., Xu, C., Futema, M., Lawson, D. J., Lotchkova, V., Schiffels, S., Hendricks, A., Danecek, P., Li, R., Floyd, J. A. B., Wain, L. V., Barroso, I., Humphries, S. E. & 18 others, Hurles, M. E., Zeggini, E., Barrett, J. C., Plagnol, V., Richards, J. B., Greenwood, C. M. T., Timpson, N., Durbin, R., Soranzo, N., Davey Smith, G., Kemp, J., Northstone, K., Paternoster, L., Shihab, H., Shin, S-Y., St Pourcain, B., Gaunt, T. & Ring, S., 1 Oct 2015, In : Nature. 526, 7571, p. 82-90 21 p.

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425 Citations (Scopus)
441 Downloads (Pure)
2014

Childhood intelligence is heritable, highly polygenic and associated with FNBP1L

Benyamin, B., Pourcain, B., Davis, O. S., Davies, G., Hansell, N. K., Brion, M-J. A., Kirkpatrick, R. M., Cents, R. A. M., Franić, S., Miller, M. B., Haworth, C. M. A., Meaburn, E., Price, T. S., Evans, D., Timpson, N., Kemp, J., Ring, S., McArdle, W., Medland, S. E., Yang, J. & 24 others, Harris, S. E., Liewald, D. C., Scheet, P., Xiao, X., Hudziak, J. J., de Geus, E. J. C., Jaddoe, V. W. V., Starr, J. M., Verhulst, F. C., Pennell, C., Tiemeier, H., Iacono, W. G., Palmer, L. J., Montgomery, G. W., Martin, N. G., Boomsma, D. I., Posthuma, D., McGue, M., Wright, M. J., Davey Smith, G., Deary, I. J., Plomin, R., Visscher, P. M. & Wellcome Trust Case Control Consortium 2 (WTCCC2), Feb 2014, In : Molecular Psychiatry. 19, 2, p. 253-258 6 p.

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129 Citations (Scopus)

Common variation near ROBO2 is associated with expressive vocabulary in infancy

St Pourcain, B., Cents, R. A. M., Whitehouse, A. J. O., Haworth, C. M. A., Davis, O. S. P., O'Reilly, P. F., Roulstone, S., Wren, Y., Ang, Q. W., Velders, F. P., Evans, D. M., Kemp, J. P., Warrington, N. M., Timpson, N. J., Ring, S. M., Verhulst, F. C., Hofman, A., Rivadeneira, F., Meaburn, E. L., Price, T. S. & 12 others, Dale, P. S., Pillas, D., Yliherva, A., Rodriguez, A., Golding, J., Jaddoe, V. W. V., Jarvelin, M. R., Plomin, R., Pennell, C. E., Tiemeier, H., Smith, G. D. & Miller, L., 16 Sep 2014, In : Nature Communications. 5, A4831.

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36 Citations (Scopus)

Does bone resorption stimulate periosteal expansion ? A cross sectional analysis of Beta-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT

Kemp, J. P., Sayers, A., Paternoster, L., Evans, D. M., Deere, K., St Pourcain, B., Timpson, N. J., Ring, S. M., Lorentzon, M., Lehtimaki, T., Eriksson, J., Kahonen, M., Raitakari, O., Laaksonen, M., Sievanen, H., Viikari, J., Lyytikainen, L-P., Smith, G. D., Fraser, W. D., Vandenput, L. & 2 others, Ohlsson, C. & Tobias, J. H., Apr 2014, In : Journal of Bone and Mineral Research. 29, 4, p. 1015-1024 10 p.

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16 Citations (Scopus)
46 Citations (Scopus)

Genetic variation associated with differential educational attainment in adults has anticipated associations with school performance in children

Ward, M. E., McMahon, G., St Pourcain, B., Evans, D. M., Rietveld, C. A., Benjamin, D. J., Koellinger, P. D., Cesarini, D., Davey Smith, G., Timpson, N. J. & Social Science Genetic Association Consortium, 2014, In : PLoS ONE. 9, 7, p. e100248

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15 Citations (Scopus)

Genome wide association identifies common variants at the SERPINA6/SERPINA1 locus influencing plasma cortisol and corticosteroid binding globulin

Bolton, J. L., Hayward, C., Direk, N., Hill, L. A., Anderson, A., Huffman, J., Campbell, H., Rudan, I., Hastie, N., Wild, S. H., Velders, F. P., Hofman, A., Uitterlinden, A. G., Lahti, J., Räikkönen, K., Kajantie, E., Widen, E., Palotie, A., Eriksson, J. G., Kaakinen, M. & 27 others, Järvelin, M-R., Timpson, N. J., Davey Smith, G., Ring, S. M., Evans, D. M., St Pourcain, B., Tanaka, T., Milaneschi, Y., Bandinelli, S., Ferrucci, L., van der Harst, P., Rosmalen, J. G. M., Bakker, S. J. L., Verweij, N., Dullaart, R. P. F., Mahajan, A., Lindgren, C. M., Morris, A., Lind, L., Ingelsson, E., Anderson, L. N., Pennell, C. E., Lye, S. J., Matthews, S. G., Eriksson, J., Mellstrom, D. & CORtisol NETwork (CORNET) Consortium, Jul 2014, In : PLoS Genetics. 10, 7, p. e1004474

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55 Citations (Scopus)

Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3

Stergiakouli, E., Gaillard, R., Tavaré, J. M., Balthasar, N., Loos, R. J., Taal, H. R., Evans, D. M., Rivadeneira, F., St Pourcain, B., Uitterlinden, A. G., Kemp, J. P., Hofman, A., Ring, S. M., Cole, T. J., Jaddoe, V. W. V., Davey Smith, G. & Timpson, N. J., 21 Jul 2014, In : Obesity.

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39 Citations (Scopus)

Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment

Kemp, J. P., Medina-Gomez, C., Estrada, K., St Pourcain, B., Heppe, D. H. M., Warrington, N. M., Oei, L., Ring, S. M., Kruithof, C. J., Timpson, N. J., Wolber, L. E., Reppe, S., Gautvik, K., Grundberg, E., Ge, B., van der Eerden, B., van de Peppel, J., Hibbs, M. A., Ackert-Bicknell, C. L., Choi, K. & 13 others, Koller, D. L., Econs, M. J., Williams, F. M. K., Foroud, T., Zillikens, M. C., Ohlsson, C., Hofman, A., Uitterlinden, A. G., Davey Smith, G., Jaddoe, V. W. V., Tobias, J. H., Rivadeneira, F. & Evans, D. M., 19 Jun 2014, In : PLoS Genetics. 10, 6, 18 p., e1004423.

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77 Citations (Scopus)