Professor Mark B Cannell

BSc(U.C.Lond.), PhD(U.C.Lond.), FRSNZ, FISHR

  • BS8 1TD

1987 …2020

Research output per year

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Research Output

2010

Non-steady-state calcium handling in failing hearts from the spontaneously hypertensive rat

Ward, M-L., Crossman, D. J., Loisell, D. S. & Cannell, MB., Nov 2010, In : Pflügers Archiv: European Journal of Physiology. 460, p. 991 - 1001 10 p.

Research output: Contribution to journalArticle (Academic Journal)

8 Citations (Scopus)

Visualization of localization microscopy data

Baddeley, D., Cannell, MB. & Soeller, C., Feb 2010, In : Microscopy and Microanalysis. 16, p. 64 - 72 8 p.

Research output: Contribution to journalArticle (Academic Journal)

79 Citations (Scopus)
2009

Light-induced dark states of organic fluochromes enable 30 nm resolution imaging in standard media

Baddeley, D., Jayasinghe, I. J., Cremer, C., Cannell, MB. & Soeller, C., Jan 2009, In : Biophysical Journal. 96, p. 22 - 24 2 p.

Research output: Contribution to journalArticle (Academic Journal)

77 Citations (Scopus)

Optical single-channel resolution imaging of the ryanodine receptor distribution in rat cardiac myocytes

Baddeley, D., Jayasinghe, I. D., Lam, L., Rossberger, S., Cannell, MB. & Soeller, C., Dec 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 52, p. 22275 - 22280 5 p.

Research output: Contribution to journalArticle (Academic Journal)

191 Citations (Scopus)

Organization of ryanodine receptors, transverse tubules, and sodium-calcium exchanger in rat myocytes

Jayasinghe, I. D., Cannell, MB. & Soeller, C., Nov 2009, In : Biophysical Journal. 97, p. 2664 - 2673 9 p.

Research output: Contribution to journalArticle (Academic Journal)

84 Citations (Scopus)

Pulling on the heart strings: a new mechanism within Starling's law of the heart?

Cannell, MB., Mar 2009, In : Circulation Research. 104, p. 715 - 716 2 p.

Research output: Contribution to journalArticle (Academic Journal)

Reversible oxidation of mitochondrial peroxiredoxin 3 in mouse heart subjected to ischemia and reperfusion

Kumar, V., KItaef, N., Hampton, MB., Cannell, MB. & Winterbourn, CC., Mar 2009, In : FEBS Letters. 583, p. 997 - 1000 3 p.

Research output: Contribution to journalArticle (Academic Journal)

31 Citations (Scopus)

Three-dimensional high-resolution imaging of cardiac proteins to construct models of intracellular Ca2+ signalling in rat ventricular myocytes

Soeller, C., Jayasinghe, I. D., Li, P., Holdem, A. V. & Cannell, MB., May 2009, In : Experimental Physiology. 94, p. 496 - 508 12 p.

Research output: Contribution to journalArticle (Academic Journal)

43 Citations (Scopus)
2008

Allosteric activation of Na+-Ca2+ exchange by L-type Ca2+ current augments the trigger flux for SR Ca2+ release in ventricular myocytes

Sobie, E. A., Cannell, MB. & Bridge, J. H. B., Apr 2008, In : Biophysical Journal. 94, p. L54 - 56 2 p.

Research output: Contribution to journalArticle (Academic Journal)

32 Citations (Scopus)

Altered calcium homeostasis does not explain the contractile deficit of diabetic cardiomyopathy

Zhang, L., Cannell, MB., Phillips, A. R. J., Cooper, G. J. S. & Ward, M-L., Aug 2008, In : Diabetes. 57, 8, p. 2158 - 2166 8 p.

Research output: Contribution to journalArticle (Academic Journal)

36 Citations (Scopus)

Ca2+ entry via AMPA-type glutamate receptors triggers Ca2+-induced Ca2+ release from ryanodine receptors in rat spiral ganglion neurons

Morton-Jones, R. T., Cannell, MB. & Housley, G. D., Apr 2008, In : Cell Calcium. 43, p. 356 - 366 10 p.

Research output: Contribution to journalArticle (Academic Journal)

21 Citations (Scopus)

Increasing sensitivity of Ca2+ spark detection in noisy images by application of a matched-filter object detection algorithm

Kong, C. H., Soeller, C. & Cannell, MB., Dec 2008, In : Biophysical Journal. 95, p. 6016 - 6024 8 p.

Research output: Contribution to journalArticle (Academic Journal)

16 Citations (Scopus)

Novel features of the rabbit transverse tubular system revealed by quantitative analysis of three-dimensional reconstructions from confocal images

Savio-Galimberti, E., Frank, J., Inoue, M., Goldhaber, J. I., Cannell, MB., Bridge, J. H. & Sachse, F. B., Aug 2008, In : Biophysical Journal. 95, p. 2053 - 2062 9 p.

Research output: Contribution to journalArticle (Academic Journal)

58 Citations (Scopus)
2007

Modelling calcium microdomains using homogenisation. Journal of theoretical biology

Higgins, E. R., Goel, P., Puglisi, J. L., Bers, D. M., Cannell, M. & Sneyd, J., 21 Jan 2007, In : Journal of Theoretical Biology. 247, 4, p. 623-644 22 p.

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)

Store-Operated Ca2+ Influx and Expression of TRPC Genes in Mouse Sinoatrial Node: Circulation research

Ju, Y. K., Chu, Y., Chaulet, H., Lai, D., Gervasio, O. L., Graham, R. M., Cannell, M. B. & Allen, D. G., 8 Jan 2007, In : Circulation Research. 100, 11, p. 1605-1614 10 p.

Research output: Contribution to journalArticle (Academic Journal)

86 Citations (Scopus)

TRPC-like conductance mediates restoration of intracellular Ca2+ in cochlear outer hair cells in the guinea pig and rat

Raybould, N. P., Jagger, D. J., Kanjhan, R., Greenwood, D., Laslo, P., Hoya, N., Soeller, C., Cannell, M. B. & Housley, G. D., 15 Jan 2007, In : Journal of Physiology. 579, Pt 1, p. 101-113 13 p.

Research output: Contribution to journalArticle (Academic Journal)

25 Citations (Scopus)
2006

A buffering SERCA pump in models of calcium dynamics

Higgins, E. R., Cannell, M. B. & Sneyd, J., 1 Jan 2006, In : Biophysical Journal. 91, 1, p. 151-163 13 p.

Research output: Contribution to journalArticle (Academic Journal)

52 Citations (Scopus)

Electrochemical detection of DNA hybridization amplified by nanoparticles. Biosensors & bioelectronics

Peng, H., Soeller, C., Cannell, M. B., Bowmaker, G. A., Cooney, R. P. & Travas-Sejdic, J., 15 Jan 2006, In : Biosens Bioelectron. 21, 9, p. 1727-1736 10 p.

Research output: Contribution to journalArticle (Academic Journal)

99 Citations (Scopus)

MICROFABRICATED DEVICE

Cannell, M. B., Cooney, R. P. & Kilmartin, P., 1 Jan 2006, Patent No. 11/ …

Research output: Patent

Three-dimensional distribution of ryanodine receptor clusters in cardiac myocytes

Chen-Izu, Y., McCulle, S. L., Ward, C. W., Soeller, C., Allen, B. M., Rabang, C., Cannell, M. B., Balke, C. W. & Izu, L. T., 1 Jan 2006, In : Biophysical Journal. 91, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle (Academic Journal)

118 Citations (Scopus)
2005

Label-free electrochemical DNA sensor based on functionalised conducting copolymer: Biosensors & bioelectronics

Peng, H., Soeller, C., Vigar, N., Kilmartin, P. A., Cannell, M. B., Bowmaker, G. A., Cooney, R. P. & Travas-Sejdic, J., 1 Jan 2005, In : Biosens Bioelectron. 20, 9, p. 1821-1828 8 p.

Research output: Contribution to journalArticle (Academic Journal)

128 Citations (Scopus)
2004

Analysing cardiac excitation-contraction coupling with mathematical models of local control. Progress in biophysics and molecular biology

Soeller, C. & Cannell, M. B., 1 Jan 2004, In : Prog. Biophys. Mol. Biol.. 85, 2-3, p. 141-162 22 p.

Research output: Contribution to journalArticle (Academic Journal)

39 Citations (Scopus)

Functional imaging: gaining new insight from biophotonic imaging. Clinical and experimental pharmacology & physiology

Cannell, M. B., 1 Jan 2004, p. 883-884. 2 p.

Research output: Contribution to conferenceOther Conference Contribution

1 Citation (Scopus)

Functional imaging: New views on lens structure and function: Clinical and experimental pharmacology & physiology

Donaldson, PJ., Grey, AC., Merriman-Smith, BR., Sisley, AMG., Soeller, C., Cannell, MB. & Jacobs, MD., 1 Jan 2004, p. 890-895. 6 p.

Research output: Contribution to conferenceOther Conference Contribution

24 Citations (Scopus)

Gap junction processing and redistribution revealed by quantitative optical measurements of connexin46 epitopes in the lens. Investigative ophthalmology & visual science

Jacobs, M. D., Soeller, C., Sisley, A. M. G., Cannell, M. B. & Donaldson, P. J., 1 Jan 2004, In : Investigative Ophthalmology and Visual Science. 45, 1, p. 191-199 9 p.

Research output: Contribution to journalArticle (Academic Journal)

45 Citations (Scopus)

Properties of Ca2+ sparks evoked by action potentials in mouse ventricular myocytes

Ershler, P. R. & Cannell, M. B., 1 Jan 2004, In : Journal of Physiology.

Research output: Contribution to journalArticle (Academic Journal)

2003

Application of two-photon flash photolysis to reveal intercellular communication and intracellular Ca[sup 2+] movements: Journal of Biomedical Optics

Soeller, C., Jacobs, M. D., Donaldson, P. J., Cannell, M. B., Jones, K. T. & Ellis-Davies, G. C. R., 1 Jan 2003, In : Journal of Biomedical Optics. 8, 3, p. 418 1 p.

Research output: Contribution to journalArticle (Academic Journal)

26 Citations (Scopus)

Noise induces up-regulation of P2X2 receptor subunit of ATP-gated ion channels in the rat cochlea

Wang, J. C-C., Raybould, N. P., Luo, L., Ryan, A. F., Cannell, M. B., Thorne, P. R. & Housley, G. D., 6 Jan 2003, In : NeuroReport. 14, 6, p. 817-823 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Probing microscopic diffusion by 2-photon flash photolysis: Measurement of isotropic and anisotropic diffusion in lens fiber cells: Microscopy research and technique

Cannell, M. B., Jacobs, M. D., Donaldson, P. J. & Soeller, C., 1 Jan 2003, In : Microscopy Research and Technique. 63, 1, p. 50-57 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Reduced contraction strength with increased intracellular [Ca2+] in left ventricular trabeculae from failing rat hearts

Ward, M-L., Pope, A. J., Loiselle, D. S. & Cannell, M. B., 15 Jan 2003, In : Journal of Physiology. 546, Pt 2, p. 537-550 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Resolving morphology and antibody labeling over large distances in tissue sections. Microscopy research and technique

Jacobs, M. D., Donaldson, P. J., Cannell, M. B. & Soeller, C., 1 Jan 2003, In : Microscopy Research and Technique. 62, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle (Academic Journal)

31 Citations (Scopus)
2002

A mode of thought in excitation-contraction coupling

Cannell, M. B. & Soeller, C., 1 Jan 2002, In : Biophysical Journal. 83, 1, p. 1-2 2 p.

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)

Estimation of the sarcoplasmic reticulum Ca2+ release flux underlying Ca2+ sparks

Soeller, C. & Cannell, M. B., 1 Jan 2002, In : Biophysical Journal. 82, 5, p. 2396-2414 19 p.

Research output: Contribution to journalArticle (Academic Journal)

63 Citations (Scopus)
2001

Location of the initiation site of calcium transients and sparks in rabbit heart Purkinje cells

Cordeiro, JM., Spitzer, KW., Giles, WR., Ershler, PE., Cannell, MB. & Bridge, JHB., 1 Jan 2001, In : Journal of Physiology. 531, 2, p. 301-314 14 p.

Research output: Contribution to journalArticle (Academic Journal)

98 Citations (Scopus)

Quantifying changes in gap junction structure as a function of lens fiber cell differentiation. Cell communication & adhesion

Jacobs, M. D., Soeller, C., Cannell, M. B. & Donaldson, P. J., 1 Jan 2001, In : Cell Communication and Adhesion. 8, 4-6, p. 349-353 5 p.

Research output: Contribution to journalArticle (Academic Journal)

The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from faecal pellets of Dermatophagoides pteronyssinus

Wan, H., Winton, HL., Soeller, C., Taylor, GW., Gruenert, DC., Thompson, PJ., Cannell, MB., Stewart, GA., Garrod, DR. & Robinson, C., Feb 2001, In : Clinical and Experimental Allergy. 31, 2, p. 279-294 16 p.

Research output: Contribution to journalArticle (Academic Journal)

211 Citations (Scopus)
2000

Quantitative structural and biochemical analyses of tight junction dynamics following exposure of epithelial cells to house dust mite allergen Der p 1

Wan, H., Winton, H. L., Soeller, C., Gruenert, DC., Thompson, P. J., Cannell, M. B., Stewart, G. A., Garrod, D. R. & Robinson, C., May 2000, In : Clinical and Experimental Allergy. 30, 5, p. 685-698 14 p., WOS:000087037700013 .

Research output: Contribution to journalArticle (Academic Journal)

138 Citations (Scopus)

Sarcomeric Ca2+ gradients during activation of frog skeletal muscle fibres imaged with confocal and two‐photon microscopy

Hollingworth, S., Soeller, C., Baylor, S. M. & Cannell, M. B., 1 Jan 2000, In : Journal of Physiology. 526, 3, p. 551-560 10 p.

Research output: Contribution to journalArticle (Academic Journal)

39 Citations (Scopus)

Tight junction properties of the immortalized human bronchial epithelial cell lines Calu-3 and 16HBE14o-

Wan, H., Winton, HL., Soeller, C., Stewart, GA., Thompson, PJ., Gruenert, DC., Cannell, MB., Garrod, DR. & Robinson, C., Jun 2000, In : European Respiratory Journal. 15, 6, p. 1058-1068 11 p., WOS:000087792000014 .

Research output: Contribution to journalArticle (Academic Journal)

117 Citations (Scopus)
1999

Mechanisms underlying calcium sparks in cardiac muscle

Cannell, M. B. & Soeller, C., 1 Jan 1999, In : Journal of General Physiology. 113, 3, p. 373-376 4 p.

Research output: Contribution to journalArticle (Academic Journal)

33 Citations (Scopus)

Two-photon microscopy: Imaging in scattering samples and three-dimensionally resolved flash photolysis: Microscopy research and technique

Soeller, C. & Cannell, M. B., 1 Jan 1999, In : Microscopy Research and Technique. 47, 3, p. 182-195 14 p.

Research output: Contribution to journalArticle (Academic Journal)

51 Citations (Scopus)
1998

Class specific inhibition of house dust mite proteinases which cleave cell adhesion, induce cell death and which increase the permeability of lung epithelium

Winton, H. L., Wan, H., Cannell, M. B., Thompson, P. J., Garrod, D. R., Stewart, G. A. & Robinson, C., 30 Jul 1998, In : British Journal of Pharmacology. 124, 6, p. 1048-1059 12 p.

Research output: Contribution to journalArticle (Academic Journal)

72 Citations (Scopus)
1997

Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure

Gomez, A. M., Valdivia, H. H., Cheng, H., Lederer, M. R., Santana, L. F., Cannell, M. B., McCune, S. A., Altschuld, R. A. & Lederer, WJ., 1 Jan 1997, In : Science. 276, 5313, p. 800-806 7 p.

Research output: Contribution to journalArticle (Academic Journal)

607 Citations (Scopus)
1995

The control of calcium release in heart muscle

Cannell, M. B., Cheng, H. & Lederer, W. J., 19 Jan 1995, In : Science. 268, 5213, p. 1045-1049 5 p.

Research output: Contribution to journalArticle (Academic Journal)

490 Citations (Scopus)
1993

Calcium Sparks - Elementary Events Underlying Excitation-Contraction Coupling in Heart-Muscle

Cheng, H., Lederer, W. J. & Cannell, M. B., 29 Jan 1993, In : Science. 262, 5134, p. 740-744 5 p.

Research output: Contribution to journalArticle (Academic Journal)

1509 Citations (Scopus)
1990

Excitation-contraction coupling in heart cells. Roles of the sodium-calcium exchange, the calcium current, and the sarcoplasmic reticulum. Annals of the New York Academy of Sciences

Lederer, W. J., Berlin, J. R., Cohen, N. M., Hadley, R. W., Bers, D. M. & Cannell, M. B., 1 Jan 1990, In : Annals of the New York Academy of Sciences. 588, 1 Embryonic Ori, p. 190-206 17 p.

Research output: Contribution to journalArticle (Academic Journal)

16 Citations (Scopus)

Kinetics, stoichiometry and role of the Na-Ca exchange mechanism in isolated cardiac myocytes

Crespo, L. M., Grantham, C. J. & Cannell, M. B., 14 Jan 1990, In : Nature. 345, 6276, p. 618-621 4 p.

Research output: Contribution to journalArticle (Academic Journal)

145 Citations (Scopus)
1987

Cellular and subcellular heterogeneity of [Ca2+]i in single heart cells revealed by fura-2

Wier, W. G., Cannell, M. B., Berlin, J. R., Marbán, E. & Lederer, W. J., 16 Jan 1987, In : Science. 235, 4786, p. 325-328 4 p.

Research output: Contribution to journalArticle (Academic Journal)

Effect of membrane potential changes on the calcium transient in single rat cardiac muscle cells

Cannell, M. B. & Lederer, W. J., 1 Jan 1987, In : Science. 238, 4832, p. 1419-1423 5 p.

Research output: Contribution to journalArticle (Academic Journal)

232 Citations (Scopus)