Research output per year
Research output per year
Research output
- 50 - 90 out of 90 results
Search results
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Imaging Ca2+ Nanosparks in Heart with a New Targeted Biosensor
Shang, W., 31 Jan 2014, In: Circulation Research. 114, 3, p. 412-420 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
54 Citations (Scopus) -
Heterogeneity of T-Tubules in Pig Hearts
Gadeberg, H. C., Bond, R. C., Kong, C., Chanoit, G., Ascione, R., Cannell, M. & James, A., 9 Jun 2016, In: PLoS ONE. 11, 6, 16 p., e0156862.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile22 Citations (Scopus)369 Downloads (Pure) -
Heterogeneity in transverse (t)-tubules in pig atria
Gadeberg, H., Bond, R., Kong, C., Cannell, M., Ascione, R., Chanoit, G. & James, A., 2014, In: Proceedings of The Physiological Society. 31Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Gap junction processing and redistribution revealed by quantitative optical measurements of connexin46 epitopes in the lens. Investigative ophthalmology & visual science
Jacobs, M. D., Soeller, C., Sisley, A. M. G., Cannell, M. B. & Donaldson, P. J., 1 Jan 2004, In: Investigative Ophthalmology and Visual Science. 45, 1, p. 191-199 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
46 Citations (Scopus) -
Extraction of sub-microscopic Ca fluxes from blurred and noisy fluorescent indicator images with a detailed model fitting approach
Kong, H. T., Laver, D. R. & Cannell, M. B., 2013, In: PLoS Computational Biology. 9, 2, p. 1-10 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
File22 Citations (Scopus)589 Downloads (Pure) -
Excitation-contraction coupling in human heart failure examined by action potential clamp in rat cardiac myocytes
Cooper, P. J., Soeller, C. & Cannell, MB., Dec 2010, In: Journal of Molecular and Cellular Cardiology. 49, p. 911 - 917 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
26 Citations (Scopus) -
Excitation-contraction coupling in heart cells. Roles of the sodium-calcium exchange, the calcium current, and the sarcoplasmic reticulum. Annals of the New York Academy of Sciences
Lederer, W. J., Berlin, J. R., Cohen, N. M., Hadley, R. W., Bers, D. M. & Cannell, M. B., 1 Jan 1990, In: Annals of the New York Academy of Sciences. 588, 1 Embryonic Ori, p. 190-206 17 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
16 Citations (Scopus) -
Estimation of the sarcoplasmic reticulum Ca2+ release flux underlying Ca2+ sparks
Soeller, C. & Cannell, M. B., 1 Jan 2002, In: Biophysical Journal. 82, 5, p. 2396-2414 19 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
65 Citations (Scopus) -
Electrochemical detection of DNA hybridization amplified by nanoparticles. Biosensors & bioelectronics
Peng, H., Soeller, C., Cannell, M. B., Bowmaker, G. A., Cooney, R. P. & Travas-Sejdic, J., 15 Jan 2006, In: Biosens Bioelectron. 21, 9, p. 1727-1736 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
100 Citations (Scopus) -
Effect of SR load and pH regulatory mechanisms on stretch-dependent Ca2+ entry during the slow force response.
Sheng, X., Cannell, M. B. & Ward, M-L., 2013, In: Journal of Molecular and Cellular Cardiology. 63, p. 37-46 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
17 Citations (Scopus) -
Effect of SR load and pH regulatory mechanisms on stretch-dependent Ca(2+) entry during the slow force response.
Shen, X., Cannell, M. B. & Ward, M-L., 1 Oct 2013, In: Journal of Molecular and Cellular Cardiology. 63, p. 37-46 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
17 Citations (Scopus) -
Effect of membrane potential changes on the calcium transient in single rat cardiac muscle cells
Cannell, M. B. & Lederer, W. J., 1 Jan 1987, In: Science. 238, 4832, p. 1419-1423 5 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
237 Citations (Scopus) -
Effect of changes in action potential spike configuration, junctional sarcoplasmic reticulum micro-architecture and altered t-tubule structure in human heart failure: Journal of Muscle Research and Cell Motility
Cannell, M. B., Crossman, D. J. & Soeller, C., 4 Jan 2006, In: Journal of Muscle Research and Cell Motility. 27, 5-7, p. 297-306 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
74 Citations (Scopus) -
Distribution and Functional Role of Inositol 1,4,5-trisphosphate Receptors in Mouse Sinoatrial Node
Ju, Y-K., Lee, B. H., Lai, D., Woodcock, E. A., Hao, G-L., Lei, M., Cannell, MB. & Allen, D. G., 2011, In: Circulation Research. 109, p. 848 - 857 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
28 Citations (Scopus) -
Differential responses of rabbit ventricular and atrial transient outward current (Ito) to the Ito modulator NS5806
Cheng, H., Cannell, M. B. & Hancox, J. C., 7 Mar 2017, In: Physiological Reports. 5, 5, 16 p., e13172.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile12 Citations (Scopus)231 Downloads (Pure) -
Depotentiation of intact rat cardiac muscle unmasks an Epac-dependent increase in myofilament Ca2+ sensitivity
Kaur, S., Kong, C., Cannell, M. & Ward, M., Jan 2016, In: Clinical and Experimental Pharmacology and Physiology. 43, 1, p. 88-94 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
7 Citations (Scopus) -
Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure
Gomez, A. M., Valdivia, H. H., Cheng, H., Lederer, M. R., Santana, L. F., Cannell, M. B., McCune, S. A., Altschuld, R. A. & Lederer, WJ., 1 Jan 1997, In: Science. 276, 5313, p. 800-806 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
629 Citations (Scopus) -
Control of sarcoplasmic reticulum Ca2+ release by stochastic RyR gating within a 3D model of the cardiac dyad and importance of induction decay for CICR termination
Cannell, M. B., Kong, H. T., Imtiaz, M. & Laver, D. R., May 2013, In: Biophysical Journal. 104, 10, p. 2149-2159 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
77 Citations (Scopus) -
Computational modelling of the initiation and development of spontaneous intracellular Ca2+ waves in ventricular myocytes
Li, P., Wei, W., Cai, X., Soeller, C., Cannell, MB. & Holden, A. V., Aug 2010, In: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 368, p. 3953 - 3965 12 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
11 Citations (Scopus) -
Comparison of the organization of t-tubules, sarcoplasmic reticulum and ryanodine receptors in rat and human ventricular myocardium
Jayasinghe, I. D., Crossman, D. J., Soeller, C. & Cannell, M. B., 2012, In: Clinical and Experimental Pharmacology and Physiology. 39, 5, p. 469-476 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
42 Citations (Scopus) -
Class specific inhibition of house dust mite proteinases which cleave cell adhesion, induce cell death and which increase the permeability of lung epithelium
Winton, H. L., Wan, H., Cannell, M. B., Thompson, P. J., Garrod, D. R., Stewart, G. A. & Robinson, C., 30 Jul 1998, In: British Journal of Pharmacology. 124, 6, p. 1048-1059 12 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
72 Citations (Scopus) -
Changes in the organization of excitation-contraction coupling structures in failing human heart
Crossman, D. J., Ruygrok, P. R., Soeller, C. & Cannell, MB., Apr 2011, In: PLoS ONE. 6(3), p. e7901 - e7901 10 p., Electronic Journal.Research output: Contribution to journal › Article (Academic Journal) › peer-review
116 Citations (Scopus) -
Changes in the calcium current among different transmural regions contributes to action potential heterogeneity in rat heart
Kim, N., Cannell, MB. & Hunter, P. J., Sep 2010, In: Progress in Biophysics and Molecular Biology. 103, p. 28 - 34 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
10 Citations (Scopus) -
Cellular Hypertrophy and Increased Susceptibility to Spontaneous Calcium-Release of Rat Left Atrial Myocytes Due to Elevated Afterload
Zhang, H., Cannell, M. B., Kim, S. J., Watson, J. J., Norman, R., C. Calaghan, S., Orchard, C. & James, A. F., 29 Dec 2015, In: PLoS ONE. 10, 12, 17 p., e0144309.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile17 Citations (Scopus)304 Downloads (Pure) -
Cellular and subcellular heterogeneity of [Ca2+]i in single heart cells revealed by fura-2
Wier, W. G., Cannell, M. B., Berlin, J. R., Marbán, E. & Lederer, W. J., 16 Jan 1987, In: Science. 235, 4786, p. 325-328 4 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Caveolin-3 KO Disrupts T-Tububle Structure and Decreases T-Tubular ICa Density in Mouse Ventricular Myocytes
Bryant, S., Kong, C., Watson, J., Gadeberg, H., Roth, D. M., Patel, H., Cannell, M., James, A. & Orchard, C., 1 Nov 2018, In: AJP - Heart and Circulatory Physiology. 315, 5, p. H1101-H1111 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile19 Citations (Scopus)202 Downloads (Pure) -
Caveolin-3 dependent loss of t-tubular ICa during hypertrophy and heart failure in mice
Bryant, S. M., Kong, C. H. T., Watson, J. J., Gadeberg, H. C., James, A. F., Cannell, M. B. & Orchard, C. H., 1 May 2018, In: Experimental Physiology. 103, 5, p. 652-665 14 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile14 Citations (Scopus)273 Downloads (Pure) -
Cardiac-specific overexpression of caveolin-3 preserves t-tubular I Ca during heart failure in mice
Kong, C. H. T., Bryant, S. M., Watson, J. J., Roth, D. M., Patel, H. H., Cannell, M. B., James, A. F. & Orchard, C. H., 1 May 2019, In: Experimental Physiology. 104, 5, p. 654-666 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile5 Citations (Scopus)225 Downloads (Pure) -
Calcium Sparks - Elementary Events Underlying Excitation-Contraction Coupling in Heart-Muscle
Cheng, H., Lederer, W. J. & Cannell, M. B., 29 Jan 1993, In: Science. 262, 5134, p. 740-744 5 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
1577 Citations (Scopus) -
Ca2+ entry via AMPA-type glutamate receptors triggers Ca2+-induced Ca2+ release from ryanodine receptors in rat spiral ganglion neurons
Morton-Jones, R. T., Cannell, MB. & Housley, G. D., Apr 2008, In: Cell Calcium. 43, p. 356 - 366 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
23 Citations (Scopus) -
Arrhythmogenic late Ca2+sparks in failing heart cells and their control by action potential configuration
Fowler, E. D., Wang, N., Hezzell, M. J., Chanoit, G. P. A., Hancox, J. C. & Cannell, M. B., 4 Feb 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 5, p. 2687-2692 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile5 Citations (Scopus)101 Downloads (Pure) -
Application of two-photon flash photolysis to reveal intercellular communication and intracellular Ca[sup 2+] movements: Journal of Biomedical Optics
Soeller, C., Jacobs, M. D., Donaldson, P. J., Cannell, M. B., Jones, K. T. & Ellis-Davies, G. C. R., 1 Jan 2003, In: Journal of Biomedical Optics. 8, 3, p. 418 1 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
28 Citations (Scopus) -
A new twist in cardiac muscle: dislocated and helicoid arrangements of myofibrillar z-disks in mammalian ventricular myocytes
Jayasinghe, I. D., Crossman, D. J., Soeller, C. & Cannell, MB., May 2010, In: Journal of Molecular and Cellular Cardiology. 48, 5, p. 964 - 971 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
20 Citations (Scopus) -
Analysing cardiac excitation-contraction coupling with mathematical models of local control. Progress in biophysics and molecular biology
Soeller, C. & Cannell, M. B., 1 Jan 2004, In: Prog. Biophys. Mol. Biol.. 85, 2-3, p. 141-162 22 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
41 Citations (Scopus) -
A mode of thought in excitation-contraction coupling
Cannell, M. B. & Soeller, C., 1 Jan 2002, In: Biophysical Journal. 83, 1, p. 1-2 2 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
1 Citation (Scopus) -
Altered distribution of ICa impairs Ca release at the t-tubules of ventricular myocytes from failing hearts
Bryant, S. M., Kong, C. H. T., Watson, J., Cannell, M. B., James, A. F. & Orchard, C. H., Sep 2015, In: Journal of Molecular and Cellular Cardiology. 86, p. 23–31 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile46 Citations (Scopus)359 Downloads (Pure) -
Altered calcium homeostasis does not explain the contractile deficit of diabetic cardiomyopathy
Zhang, L., Cannell, MB., Phillips, A. R. J., Cooper, G. J. S. & Ward, M-L., Aug 2008, In: Diabetes. 57, 8, p. 2158 - 2166 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
40 Citations (Scopus) -
Allosteric activation of Na+-Ca2+ exchange by L-type Ca2+ current augments the trigger flux for SR Ca2+ release in ventricular myocytes
Sobie, E. A., Cannell, MB. & Bridge, J. H. B., Apr 2008, In: Biophysical Journal. 94, p. L54 - 56 2 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
34 Citations (Scopus) -
A buffering SERCA pump in models of calcium dynamics
Higgins, E. R., Cannell, M. B. & Sneyd, J., 1 Jan 2006, In: Biophysical Journal. 91, 1, p. 151-163 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
59 Citations (Scopus) -
4D Super-Resolution Microscopy with Conventional Fluorophores and Single Wavelength Excitation in Optically Thick Cells and Tissues
Baddeley, D., Crossman, D., Rossberger, S., Cheyne, J., Montgomery, J., Isuru, D., Jayasinghe, ID., Cremer, C., Cannell, MB. & Soeller, C., 2011, In: PLoS ONE. 6, p. 1-10 10 p., e20645.Research output: Contribution to journal › Article (Academic Journal) › peer-review
107 Citations (Scopus)