Dr Mark Bond

B.Sc.(Nott.), Ph.D.(Bristol)

  • BS2 8HW

20042020

Research output per year

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Research Output

  • 26 Article (Academic Journal)
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Article (Academic Journal)
2020

Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD

McNeill, M. C., Wray, J., Sala-Newby, G. B., Hindmarch, C. C. T., Smith, S. A., Ebrahimighaei, R., Newby, A. C. & Bond, M., 1 Jul 2020, In : Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1867, 7, 16 p., 118691.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
41 Downloads (Pure)
2019

Antiproliferative and Antimigratory Effects of a Novel YAP-TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking

Smith, S. A., Sessions, R. B., Shoemark, D. K., Williams, C., Ebrahimighaei, R., McNeill, M. C., Crump, M. P., McKay, T. R., Harris, G., Newby, A. C. & Bond, M., 14 Feb 2019, In : Journal of Medicinal Chemistry. 62, 3, p. 1291-1305 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
14 Citations (Scopus)
328 Downloads (Pure)
Open Access
File
3 Citations (Scopus)
22 Downloads (Pure)

Ending restenosis: Inhibition of vascular smooth muscle cell proliferation by cAMP

Smith, S. A., Newby, A. C. & Bond, M., 16 Nov 2019, In : Cells. 8, 11, 28 p., 1447.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
81 Downloads (Pure)
2018

Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis

Greenhough, A., Bagley, C., Heesom, K., Gurevich, D., Gay, D., Bond, M., Collard, T., Paraskeva, C., Martin, P., Sansom, O. J., Malik, K. & Williams, A., Aug 2018, In : EMBO Molecular Medicine. 10, 8, 13 p., e8699.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
12 Citations (Scopus)
240 Downloads (Pure)

Dual role of CREB in the regulation of VSMC proliferation: mode of activation determines pro- or anti-mitogenic function

Hudson, C., Kimura, T. E., Duggirala, A., Sala-Newby, G. B., Newby, A. C. & Bond, M., 20 Mar 2018, In : Scientific Reports. 8, 15 p., 4904.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
8 Citations (Scopus)
248 Downloads (Pure)
2017

Cigarette smoke extract profoundly suppresses TNFα-mediated proinflammatory gene expression through upregulation of ATF3 in human coronary artery endothelial cells

Teasdale, J. E., Hazell, G. G. J., Peachey, A. M. G., Sala-Newby, G. B., Hindmarch, C. C. T., McKay, T. R., Bond, M., Newby, A. C. & White, S. J., 6 Jan 2017, In : Scientific Reports. 7, 10 p., 39945.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
11 Citations (Scopus)
377 Downloads (Pure)

Divergent Regulation of Actin Dynamics and Megakaryoblastic Leukemia-1 and -2 (Mkl1/2) by cAMP in Endothelial and Smooth Muscle Cells

Smith, M., Hudson, C., Kimura-Wozniak, T., White, S., Sala-Newby, G., Newby, A. & Bond, M., 16 Jun 2017, In : Scientific Reports. 7, 13 p., 3681.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
233 Downloads (Pure)

Functional and cardioprotective effects of simultaneous and individual activation of protein kinase A and Epac

Khaliulin, I., Bond, M., James, A. F., Dyar, Z., Amini, R., Johnson, J. L. & Suleiman, M-S., 24 Feb 2017, In : British Journal of Pharmacology. 174, 6, p. 438-453 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
8 Citations (Scopus)
284 Downloads (Pure)

Regulation of epigenetic modifiers, including KDM6B, by interferon-γ and interleukin-4 in human macrophages

Yildirim-Buharalioğlu, G., Bond, M., Sala-Newby, G. B., Hindmarch, C. C. T. & Newby, A. C., 8 Feb 2017, In : Frontiers in Immunology. 8, FEB, p. 1-18 18 p., 92.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
9 Citations (Scopus)
252 Downloads (Pure)
2016

The Hippo pathway mediates inhibition of vascular smooth muscle cell proliferation by cAMP

Kimura-Wozniak, T., Duggirala, A., Smith, M. C., White, S. J., Sala-Newby, G., Newby, A. C. & Bond, M., Jan 2016, In : Journal of Molecular and Cellular Cardiology. 90, p. 1-10 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
39 Citations (Scopus)
401 Downloads (Pure)

Zoledronate upregulates MMP-9 and -13 in rat vascular smooth muscle cells by inducing oxidative stress

Arun, M. Z., Reel, B., Sala-Newby, G. B., Bond, M., Tsaousi, A., Maskell, P. & Newby, A. C., 18 Apr 2016, In : Drug Design, Development and Therapy. 2016, 10, p. 1453-1460 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
10 Citations (Scopus)
275 Downloads (Pure)
2015

cAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1

Duggirala, A., Kimura, T. E., Sala-Newby, G. B., Johnson, J. L., Wu, Y-J., Newby, A. C. & Bond, M., Feb 2015, In : Journal of Molecular and Cellular Cardiology. 79, p. 157-168 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
6 Citations (Scopus)
256 Downloads (Pure)
2014

Inhibition of Egr1 expression underlies the anti-mitogenic effects of cAMP in vascular smooth muscle cells

Kimura, T. E., Duggirala, A., Hindmarch, C. C. T., Hewer, R. C., Cui, M-Z., Newby, A. C. & Bond, M., Jul 2014, In : Journal of Molecular and Cellular Cardiology. 72, p. 9-19 11 p.

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)
2011

Adhesion-dependent Skp2 transcription requires selenocysteine tRNA gene transcription-activating factor (STAF)

Ivette, H-N., Graciela B, S-N., Andras, P., Gary R, K., Newby, AC. & Bond, M., 2011, In : Biochemical Journal. 436, p. 133-143

Research output: Contribution to journalArticle (Academic Journal)

15 Citations (Scopus)

PKA and Epac synergistically inhibit smooth muscle cell proliferation

Hewer, RC., Sala-Newby, GB., Wu, YJ., Newby, AC. & Bond, M., Jan 2011, In : Journal of Molecular and Cellular Cardiology. 50, 1, p. 87 - 98 12 p.

Research output: Contribution to journalArticle (Academic Journal)

69 Citations (Scopus)

Proliferation unleashed: the role of Skp2 in vascular smooth muscle cell proliferation

Bond, M. & Wu, Y-J., Jan 2011, In : Frontiers in Bioscience. 1, 16, p. 1517 - 1535 19 p.

Research output: Contribution to journalArticle (Academic Journal)

12 Citations (Scopus)
2009

S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo

Wu, Y-J., Sala-Newby, GB., Shu, KT., Yeh, HI., Nakayama, K., Nakayama, K., Newby, AC. & Bond, M., Nov 2009, In : Journal of Vascular Surgery. 50, 5, p. 1135 - 1142 8 p.

Research output: Contribution to journalArticle (Academic Journal)

33 Citations (Scopus)
2008

Acute inhibition of superoxide formation and Rac(1) activation by nitric oxide and iloprost in human vascular smooth muscle cells in response to the thromboxane A(2) analogue, U46619

Muzaffar, S., Shukla, N., Bond, M., Sala-Newby, GB., Angelini, G., Newby, AC. & Jeremy, JY., Apr 2008, In : Prostaglandins Leukot Essent Fatty Acids. 78, p. 247 - 255 9 p.

Research output: Contribution to journalArticle (Academic Journal)

22 Citations (Scopus)

Exogenous Hydrogen Sulfide Inhibits Superoxide Formation, NOX-1 Expression and Rac(1) Activity in Human Vascular Smooth Muscle Cells

Muzaffar, S., Shukla, N., Bond, M., Newby, AC., Angelini, G., Sparatore, A., Del Soldato, P. & Jeremy, JY., May 2008, In : Journal of Vascular Research. 7;45(6), p. 521 - 528 8 p.

Research output: Contribution to journalArticle (Academic Journal)

93 Citations (Scopus)

Rho GTPase, Rac1, regulates Skp2 levels, vascular smooth muscle cell proliferation, and intima formation in vitro and in vivo

Bond, M., Wu, Y-J., Sala-Newby, GB. & Newby, AC., 2008, In : Cardiovascular Research. 80, 2, p. 290 - 298 9 p.

Research output: Contribution to journalArticle (Academic Journal)

44 Citations (Scopus)

Superoxide from NADPH oxidase upregulates type 5 phosphodiesterase in human vascular smooth muscle cells: inhibition with iloprost and NONOate

Muzaffar, S., Shukla, N., Bond, M., Sala-Newby, GB., Newby, AC., Angelini, G. & Jeremy, JY., Jul 2008, In : British Journal of Pharmacology. 155, p. 847 - 856 10 p.

Research output: Contribution to journalArticle (Academic Journal)

34 Citations (Scopus)
2006

Altered S-Phase Kinase-Associated Protein-2 Levels Are a Major Mediator of Cyclic Nucleotide-Induced Inhibition of Vascular Smooth Muscle Cell Proliferation

Wu, Y-J., Bond, M., Sala-Newby, GB. & Newby, AC., May 2006, In : Circulation Research. 98 (9), p. 1141 - 1150 10 p.

Research output: Contribution to journalArticle (Academic Journal)

61 Citations (Scopus)

Biphasic effect of p21Cip1 on smooth muscle cell proliferation: Role of PI 3-kinase and Skp2-mediated degradation

Bond, M., Sala-Newby, GB., Wu, Y-J. & Newby, AC., Jan 2006, In : Cardiovascular Research. 69 (1), p. 198 - 206 9 p.

Research output: Contribution to journalArticle (Academic Journal)

34 Citations (Scopus)
2005

Regulation of vascular smooth muscle cell proliferation, migration and death by heparan sulfate 6-O-endosulfatase 1

Sala-Newby, GB., George, SJ., Bond, M., Dhoot, GK. & Newby, AC., Nov 2005, In : FEBS Letters. 579 (28), p. 6493 - 6498 6 p.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)
2004

Focal Adhesion Kinase (FAK)-dependent Regulation of S-phase Kinase-associated Protein-2 (Skp-2) Stability: a novel mechanism regulating smooth muscle cell proliferation

Bond, M., Sala-Newby, GB. & Newby, AC., 3 Sep 2004, In : Journal of Biological Chemistry. 279 (36), p. 37304 - 37310 7 p.

Research output: Contribution to journalArticle (Academic Journal)

56 Citations (Scopus)