Research output per year
Research output per year
Research output
- 29 results
Search results
-
2024
A de novo designed coiled coil-based switch regulates the microtubule motor kinesin-1
Cross, J. A. A., Dawson, W. M., Shukla, S. R., Weijman, J. F. M. S., Mantell, J. M., Dodding, M. P. & Woolfson, D. N., Jul 2024, In: Nature Chemical Biology. 20, 7, p. 916-923 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
CryoET reveals actin filaments within platelet microtubules
Tsuji, C., Bradshaw, M., Allen, M. F., Jackson, M. L., Mantell, J. M., Borucu, U., Poole, A. W., Verkade, P., Hers, I., Paul, D. M. & Dodding, M. P., 16 Jul 2024, In: Nature Communications. 15, 1, 8 p., 5967 .Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Rescue of mitochondrial import failure by intercellular organellar transfer
Needs, H. I., Glover, E., Pereira, G. C., Witt, A., Hübner, W., Dodding, M. P., Henley, J. M. & Collinson, I., 2 Feb 2024, In: Nature Communications. 15, 1, 17 p., 988.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access2 Citations (Scopus) -
2023
Allosteric regulation of a molecular motor through de novo protein design
Cross, J. A. A., Dawson, W. M., Shukla, S. R., Weijman, J. F. M. S., Mantell, J. M., Dodding, M. P. & Woolfson, D. N., 17 Oct 2023, In: bioRxiv.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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2022
De novo designed peptides for cellular delivery and subcellular localisation
Rhys, G. G., Cross, J. A., Dawson, W. M., Thompson, H. F., Shanmugaratnam, S., Savery, N. J., Dodding, M. P., Höcker, B. & Woolfson, D. N., 1 Sept 2022, In: Nature Chemical Biology. 18, 9, p. 999-1004 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile16 Citations (Scopus)259 Downloads (Pure) -
Molecular architecture of the autoinhibited kinesin-1 lambda particle
Weijman, J. F. M. S., Yadav Kadapalakere, S., Surridge, K. J., Cross, J. A. A., Mantell, J. M., Woolfson, D. N., Berger-Schaffitzel, C. H. & Dodding, M. P., 16 Sept 2022, In: Science Advances.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access8 Citations (Scopus) -
2021
Fragment-linking peptide design yields a high-affinity ligand for microtubule-based transport
Cross, J. A., Chegkazi, M. S., Steiner, R. A., Woolfson, D. N. & Dodding, M. P., 16 Sept 2021, In: Cell Chemical Biology. 28, 9, p. 1347-1355.e5 15 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile6 Citations (Scopus)84 Downloads (Pure) -
Kinesin-1 captures RNA cargo in its adaptable coils
Cross, J. A. A., Woolfson, D. N. & Dodding, M. P., 1 Jul 2021, In: Genes and Development. 35, 13-14, p. 937-939 3 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile6 Citations (Scopus)55 Downloads (Pure) -
Molecular mechanism for kinesin-1 direct membrane recognition
Antón, Z., Weijman, J. F., Williams, C., Moody, E. R. R., Mantell, J., Yip, Y. Y., Cross, J. A., Williams, T. A., Steiner, R. A., Crump, M., Woolfson, D. N. & Dodding, M. P., 28 Jul 2021, In: Science Advances. 7, 31, 15 p., eabg6636.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile6 Citations (Scopus)182 Downloads (Pure) -
2020
In situ cryo-electron tomography reveals filamentous actin within the microtubule lumen
Paul, D. M., Mantell, J. M., Borucu, U., Coombs, J., Surridge, K. J., Squire, J. M., Verkade, P. & Dodding, M. P., 1 Jun 2020, In: Journal of Cell Biology. 219, 9, 14 p., e201911154.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile25 Citations (Scopus)143 Downloads (Pure) -
2018
Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors
Pernigo, S., Chegkazi, M. S., Yip, Y. Y., Treacy, C., Glorani, G., Hansen, K., Politis, A., Bui, S., Dodding, M. P. & Steiner, R. A., 16 Oct 2018, In: eLife. 7, e38362.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile16 Citations (Scopus)282 Downloads (Pure) -
2017
A small-molecule activator of kinesin-1 drives remodeling of the microtubule network
Randall, T. S., Yip, Y. Y., Wallock-Richards, D. J., Pfisterer, K., Sanger, A., Ficek, W., Steiner, R. A., Beavil, A. J., Parsons, M. & Dodding, M. P., 26 Dec 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 52, p. 13738-13743 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile34 Citations (Scopus)382 Downloads (Pure) -
SKIP controls lysosome positioning using a composite kinesin-1 heavy and light chain-binding domain
Sanger, A., Yip, Y. Y., Randall, T. S., Pernigo, S., Steiner, R. A. & Dodding, M. P., May 2017, In: Journal of Cell Science. 130, 9, p. 1637-1651 15 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile25 Citations (Scopus)355 Downloads (Pure) -
2016
Folliculin - A tumor suppressor at the intersection of metabolic signaling and membrane traffic
Dodding, M. P., 29 Jun 2016, In: Small GTPases. 8, 2, p. 100-105 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile6 Citations (Scopus)327 Downloads (Pure) -
Folliculin directs the formation of a Rab34-RILP complex to control the nutrient-dependent dynamic distribution of lysosomes
Starling, G. P., Yip, Y. Y., Sanger, A., Morton, P. E., Eden, E. R. & Dodding, M. P., 1 Jun 2016, In: EMBO Reports. 17, 6, p. 823-841 19 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile74 Citations (Scopus)351 Downloads (Pure) -
The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1
Twelvetrees, A. E., Pernigo, S., Sanger, A., Guedes-Dias, P., Schiavo, G., Steiner, R. A., Dodding, M. P. & Holzbaur, E. L. F., 1 Jun 2016, In: Neuron. 90, 5, p. 1000-1015 16 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile81 Citations (Scopus)314 Downloads (Pure) -
The light chains of kinesin-1 are autoinhibited
Yip, Y. Y., Pernigo, S., Sanger, A., Xu, M., Parsons, M., Steiner, R. A. & Dodding, M. P., Mar 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 9, p. 2418-2423 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile40 Citations (Scopus)290 Downloads (Pure) -
2013
Structural basis for kinesin-1:cargo recognition
Pernigo, S., Lamprecht, A., Steiner, R. A. & Dodding, M. P., 19 Apr 2013, In: Science. 340, 6130, p. 356-9 4 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
74 Citations (Scopus) -
Vaccinia virus F11 promotes viral spread by acting as a PDZ-containing scaffolding protein to bind myosin-9A and inhibit RhoA signaling
Handa, Y., Durkin, C. H., Dodding, M. P. & Way, M., 17 Jul 2013, In: Cell Host & Microbe. 14, 1, p. 51-62 12 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
41 Citations (Scopus) -
2012
Clathrin potentiates vaccinia-induced actin polymerization to facilitate viral spread
Humphries, A. C., Dodding, M. P., Barry, D. J., Collinson, L. M., Durkin, C. H. & Way, M., 13 Sept 2012, In: Cell Host & Microbe. 12, 3, p. 346-59 14 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
43 Citations (Scopus) -
2011
A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome
Dodding, M. P., Mitter, R., Humphries, A. C. & Way, M., 16 Nov 2011, In: EMBO Journal. 30, 22, p. 4523-38 16 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
74 Citations (Scopus) -
2009
An E2-F12 complex is required for intracellular enveloped virus morphogenesis during vaccinia infection
Dodding, M. P., Newsome, T. P., Collinson, L. M., Edwards, C. & Way, M., May 2009, In: Cellular Microbiology. 11, 5, p. 808-24 17 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
35 Citations (Scopus) -
F11-mediated inhibition of RhoA signalling enhances the spread of vaccinia virus in vitro and in vivo in an intranasal mouse model of infection
Cordeiro, J. V., Guerra, S., Arakawa, Y., Dodding, M. P., Esteban, M. & Way, M., 30 Dec 2009, In: PLoS ONE. 4, 12, p. e8506Research output: Contribution to journal › Article (Academic Journal) › peer-review
51 Citations (Scopus) -
Nck- and N-WASP-dependent actin-based motility is conserved in divergent vertebrate poxviruses
Dodding, M. P. & Way, M., 17 Dec 2009, In: Cell Host & Microbe. 6, 6, p. 536-50 15 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
44 Citations (Scopus) -
Vaccinia-induced epidermal growth factor receptor-MEK signalling and the anti-apoptotic protein F1L synergize to suppress cell death during infection
Postigo, A., Martin, M. C., Dodding, M. P. & Way, M., Aug 2009, In: Cellular Microbiology. 11, 8, p. 1208-18 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
32 Citations (Scopus) -
2008
Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation
Mortuza, G. B., Dodding, M. P., Goldstone, D. C., Haire, L. F., Stoye, J. P. & Taylor, I. A., 7 Mar 2008, In: Journal of Molecular Biology. 376, 5, p. 1493-508 16 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
47 Citations (Scopus) -
2007
TRIM5 alpha cytoplasmic bodies are highly dynamic structures
Campbell, E. M., Dodding, M. P., Yap, M. W., Wu, X., Gallois-Montbrun, S., Malim, M. H., Stoye, J. P. & Hope, T. J., Jun 2007, In: Molecular Biology of the Cell. 18, 6, p. 2102-11 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
58 Citations (Scopus) -
2006
Trim-cyclophilin A fusion proteins can restrict human immunodeficiency virus type 1 infection at two distinct phases in the viral life cycle
Yap, M. W., Dodding, M. P. & Stoye, J. P., Apr 2006, In: Journal of Virology. 80, 8, p. 4061-7 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
67 Citations (Scopus) -
2005
Capsid processing requirements for abrogation of Fv1 and Ref1 restriction
Dodding, M. P., Bock, M., Yap, M. W. & Stoye, J. P., Aug 2005, In: Journal of Virology. 79, 16, p. 10571-7 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
41 Citations (Scopus)