Control of beta-Branching in Kalimantacin Biosynthesis: Application of Direct Observe 13C NMR to Polyketide Programming.

Walker, P., Williams, C., Weir, A., Wang, L., Crosby, J., Race, P., Simpson, T., Willis, C. & Crump, M., 28 Aug 2019, In : Angewandte Chemie. 58, 36, p. 12446-12450 5 p.

Research output: Contribution to journal › Article

Maternal transmission of an Igf2r domain 11: IGF2 binding mutant allele (Igf2r ^I1565A) results in partial lethality, overgrowth and intestinal adenoma progression

Hughes, J., Surakhy, M., Can, S., Ducker, M., Davies, N., Szele, F., Bühnemann, C., Carter, E., Trikin, R., Crump, M. P., Frago, S. & Hassan, A. B., 6 Aug 2019, In : Scientific Reports. 9, 1, 16 p., 11388.

Research output: Contribution to journal › Article

Stabilizing and Understanding a Miniprotein by Rational Redesign

Porter Goff, K., Nicol, D., Williams, C., Crump, M., Zieleniewski, F., Samphire, J., Baker, E. & Woolfson, D., 16 Jul 2019, In : Biochemistry. 58, 28, p. 3060-3064 5 p.

Research output: Contribution to journal › Article

The Aminotriazole Antagonist Cmpd-1 Stabilises a Novel Inactive State of the Adenosine 2A Receptor

Landin, E., Lovera, S., de Fabritiis, G., Kelm, S., Mercier, J., McMillan, D., Sessions, R., Taylor, R. J., Sands, Z., Joedicke, L. & Crump, M., 8 Jul 2019, In : Angewandte Chemie - International Edition. 58, 28, p. 9399-9403 5 p.

Research output: Contribution to journal › Article

Anti-proliferative and anti-migratory effects of a novel YAP-TEAD interaction inhibitor identified using in silico molecular docking

Smith, S., Sessions, R., Shoemark, D., Williams, C., Ebrahimighaei, R., McNeill, M., Crump, M., McKay, T. R., Harris, G., Newby, A. & Bond, M., 14 Feb 2019, In : Journal of Medicinal Chemistry. 62, 3, p. 1291-1305 15 p.

Research output: Contribution to journal › Article

Defining the genes for the final steps in biosynthesis of the complex polyketide antibiotic mupirocin by Pseudomonas fluorescens NCIMB10586

Connolly, J. A., Wilson, A., Macioszek, M., Song, Z., Wang, L., Mohammad, H. H., Yadav, M., di Martino, M., Miller, C. E., Hothersall, J., Haines, A. S., Stephens, E. R., Crump, M. P., Willis, C. L., Simpson, T. J., Winn, P. J. & Thomas, C. M., 7 Feb 2019, In : Scientific Reports. 9, 9 p., 1542.

Research output: Contribution to journal › Article

A biomimetic receptor for glucose

Tromans, R. A., Carter, T. S., Chabanne, L., Crump, M. P., Li, H., Matlock, J. V., Orchard, M. G. & Davis, A. P., Jan 2019, In : Nature Chemistry. 11, 1, p. 52-56 5 p.

Research output: Contribution to journal › Article

The molecular basis of protein toxin HicA– dependent binding of the protein antitoxin HicB to DNA

Winter, A. J., Williams, C., Isupov, M. N., Crocker, H., Gromova, M., Marsh, P., Wilkinson, O. J., Dillingham, M. S., Harmer, N. J., Titball, R. W. & Crump, M. P., 14 Dec 2018, In : Journal of Biological Chemistry. 293, 50, p. 19429-19440 12 p.

Research output: Contribution to journal › Article

A Rieske oxygenase/epoxide hydrolase-catalysed reaction cascade creates oxygen heterocycles in mupirocin biosynthesis

Wang, L., Parnell, A., Williams, C., Bakar, N. A., Challand, M. R., van der Kamp, M. W., Simpson, T. J., Race, P. R., Crump, M. P. & Willis, C. L., Dec 2018, In : Nature Catalysis. 1, 12, p. 968-976 9 p.

Research output: Contribution to journal › Article

The de novo design of a biocompatible and functional integral membrane protein using minimal sequence complexity

Lalaurie, C. J., Dufour, V., Meletiou, A., Ratcliffe, S., Harland, A., Wilson, O., Vamasiri, C., Shoemark, D. K., Williams, C., Arthur, C. J., Sessions, R. B., Crump, M. P., Anderson, J. L. R. & Curnow, P., 1 Oct 2018, In : Scientific Reports. 8, 12 p., 14564.

Research output: Contribution to journal › Article